NO20080440L - Non-steroidal progesterone receptor modulators - Google Patents
Non-steroidal progesterone receptor modulatorsInfo
- Publication number
- NO20080440L NO20080440L NO20080440A NO20080440A NO20080440L NO 20080440 L NO20080440 L NO 20080440L NO 20080440 A NO20080440 A NO 20080440A NO 20080440 A NO20080440 A NO 20080440A NO 20080440 L NO20080440 L NO 20080440L
- Authority
- NO
- Norway
- Prior art keywords
- receptor modulators
- progesterone receptor
- therapy
- prophylaxis
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse vedrører ikke-steroide progesteronreseptormodulatorer med generell formel (I), en fremgangsmåte for deres fremstilling, anvendelsen av progesteronreseptormodulatorene for fremstilling av medikamenter og farmasøytiske preparater som omfatter disse forbindelsene. Forbindelsene ifølge oppfinnelsen er passende for terapien og profylaksen av gynekologiske forstyrrelser slik som endometriose, leiomyomer i livmoren, feilaktig blødning og dysmenoré og til terapien og profylaksen av hormonavhengige tumorer og til anvendelse for kvinnelig fertilitetskontroll og til hormonerstatningsterapi.The present invention relates to non-steroidal progesterone receptor modulators of general formula (I), a process for their preparation, the use of the progesterone receptor modulators for the preparation of drugs and pharmaceutical compositions comprising these compounds. The compounds of the invention are suitable for the therapy and prophylaxis of gynecological disorders such as endometriosis, uterine leiomyomas, erroneous bleeding and dysmenorrhea, and for the therapy and prophylaxis of hormone dependent tumors and for use in female fertility control and hormone replacement therapy.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005030292A DE102005030292A1 (en) | 2005-06-24 | 2005-06-24 | Nonsteroidal progesterone receptor modulators |
| PCT/EP2006/006531 WO2006136461A2 (en) | 2005-06-24 | 2006-06-22 | Non-steroidal progesterone receptor modulators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20080440L true NO20080440L (en) | 2008-03-25 |
Family
ID=37199176
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20080440A NO20080440L (en) | 2005-06-24 | 2008-01-23 | Non-steroidal progesterone receptor modulators |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1902049A2 (en) |
| JP (1) | JP2008543910A (en) |
| KR (1) | KR20080030622A (en) |
| CN (1) | CN101248066A (en) |
| AR (1) | AR054519A1 (en) |
| AU (1) | AU2006261048A1 (en) |
| BR (1) | BRPI0611903A2 (en) |
| CA (1) | CA2611897A1 (en) |
| CR (1) | CR9598A (en) |
| DE (1) | DE102005030292A1 (en) |
| DO (1) | DOP2006000148A (en) |
| EA (1) | EA200702524A1 (en) |
| EC (1) | ECSP078044A (en) |
| GT (1) | GT200600271A (en) |
| IL (1) | IL188021A0 (en) |
| MX (1) | MX2008000072A (en) |
| NO (1) | NO20080440L (en) |
| PE (1) | PE20070125A1 (en) |
| TW (1) | TW200740778A (en) |
| UY (1) | UY29624A1 (en) |
| WO (1) | WO2006136461A2 (en) |
| ZA (1) | ZA200800690B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY30805A1 (en) * | 2006-12-21 | 2008-07-31 | Bayer Schering Pharma Ag | NON-STEROID MODULATORS OF PROGESTERONE RECEPTORS |
| DE102007032800A1 (en) * | 2007-07-10 | 2009-01-15 | Bayer Schering Pharma Aktiengesellschaft | Nonsteroidal progesterone receptor modulators |
| DE102007058747A1 (en) * | 2007-12-05 | 2009-06-10 | Bayer Schering Pharma Aktiengesellschaft | Nonsteroidal progesterone receptor modulators |
| JP2011519916A (en) * | 2008-07-02 | 2011-07-14 | ファーマコステック カンパニー リミテッド | Method for producing amide derivative |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19856475A1 (en) * | 1998-11-27 | 2000-05-31 | Schering Ag | Nonsteroidal anti-inflammatories |
| EP1344776A1 (en) * | 2002-03-11 | 2003-09-17 | Schering Aktiengesellschaft | 5- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -phtalide and 6- 2-hydroxy-3-[1-(3-trifluoromethylphenyl)-cyclopropyl]-propionylamino -4-methyl-2,3-benzoxazin-1-one derivatives with progesterone receptor modulating activity for use in fertility control, hormone replacement therapy and the treatment of gynecological disorders |
| BRPI0412231A (en) * | 2003-07-01 | 2006-08-22 | Schering Ag | heterocyclically substituted pentanol derivatives, processes for their preparation and application as inflammation inhibitors |
-
2005
- 2005-06-24 DE DE102005030292A patent/DE102005030292A1/en not_active Ceased
-
2006
- 2006-06-22 AU AU2006261048A patent/AU2006261048A1/en not_active Abandoned
- 2006-06-22 CN CNA2006800308707A patent/CN101248066A/en active Pending
- 2006-06-22 EP EP06762404A patent/EP1902049A2/en not_active Withdrawn
- 2006-06-22 EA EA200702524A patent/EA200702524A1/en unknown
- 2006-06-22 JP JP2008517444A patent/JP2008543910A/en active Pending
- 2006-06-22 CA CA002611897A patent/CA2611897A1/en not_active Abandoned
- 2006-06-22 KR KR1020087001793A patent/KR20080030622A/en not_active Application Discontinuation
- 2006-06-22 WO PCT/EP2006/006531 patent/WO2006136461A2/en active Application Filing
- 2006-06-22 MX MX2008000072A patent/MX2008000072A/en not_active Application Discontinuation
- 2006-06-22 BR BRPI0611903-4A patent/BRPI0611903A2/en not_active Application Discontinuation
- 2006-06-23 TW TW095122742A patent/TW200740778A/en unknown
- 2006-06-26 UY UY29624A patent/UY29624A1/en not_active Application Discontinuation
- 2006-06-26 DO DO2006000148A patent/DOP2006000148A/en unknown
- 2006-06-26 PE PE2006000733A patent/PE20070125A1/en not_active Application Discontinuation
- 2006-06-27 AR ARP060102750A patent/AR054519A1/en unknown
- 2006-06-28 GT GT200600271A patent/GT200600271A/en unknown
-
2007
- 2007-12-10 IL IL188021A patent/IL188021A0/en unknown
- 2007-12-17 CR CR9598A patent/CR9598A/en not_active Application Discontinuation
- 2007-12-21 EC EC2007008044A patent/ECSP078044A/en unknown
-
2008
- 2008-01-23 NO NO20080440A patent/NO20080440L/en not_active Application Discontinuation
- 2008-01-23 ZA ZA200800690A patent/ZA200800690B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CR9598A (en) | 2008-04-09 |
| EP1902049A2 (en) | 2008-03-26 |
| PE20070125A1 (en) | 2007-02-14 |
| KR20080030622A (en) | 2008-04-04 |
| EA200702524A1 (en) | 2008-06-30 |
| BRPI0611903A2 (en) | 2010-10-05 |
| TW200740778A (en) | 2007-11-01 |
| CN101248066A (en) | 2008-08-20 |
| JP2008543910A (en) | 2008-12-04 |
| MX2008000072A (en) | 2008-03-24 |
| GT200600271A (en) | 2007-02-05 |
| ECSP078044A (en) | 2008-01-23 |
| WO2006136461A2 (en) | 2006-12-28 |
| WO2006136461A3 (en) | 2007-03-15 |
| DE102005030292A1 (en) | 2007-01-11 |
| DOP2006000148A (en) | 2007-07-15 |
| UY29624A1 (en) | 2007-01-31 |
| CA2611897A1 (en) | 2006-12-28 |
| IL188021A0 (en) | 2008-03-20 |
| ZA200800690B (en) | 2009-09-30 |
| AU2006261048A1 (en) | 2006-12-28 |
| AR054519A1 (en) | 2007-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |