NO20075209L - Substituerte aryl 1,4-pyrazinderivater - Google Patents
Substituerte aryl 1,4-pyrazinderivaterInfo
- Publication number
- NO20075209L NO20075209L NO20075209A NO20075209A NO20075209L NO 20075209 L NO20075209 L NO 20075209L NO 20075209 A NO20075209 A NO 20075209A NO 20075209 A NO20075209 A NO 20075209A NO 20075209 L NO20075209 L NO 20075209L
- Authority
- NO
- Norway
- Prior art keywords
- substituted aryl
- pyrazine derivatives
- crf1
- disorders
- diseases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Addiction (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
Abstract
Oppfinnelsen er rettet til forbindelser med formel (I), beskrevet heri, så vel som farmasøytisk akseptable salter derav, som fungerer som CRF1 antagonister og er anvendbare ved behandling av lidelser og sykdommer forbundet med CRF1-reseptorer, inkludert CNS-relaterte lidelser og sykdommer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66291705P | 2005-03-17 | 2005-03-17 | |
PCT/IB2006/000564 WO2006114666A1 (en) | 2005-03-17 | 2006-03-06 | SUBSTITUTED ARYL 1,4-PYRAZlNE DERIVATIVES |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20075209L true NO20075209L (no) | 2007-10-11 |
Family
ID=36617394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20075209A NO20075209L (no) | 2005-03-17 | 2007-10-11 | Substituerte aryl 1,4-pyrazinderivater |
Country Status (26)
Country | Link |
---|---|
US (1) | US20060211710A1 (no) |
EP (1) | EP1871763A1 (no) |
JP (1) | JP2008533124A (no) |
KR (1) | KR20070113294A (no) |
CN (1) | CN101160304A (no) |
AP (1) | AP2007004174A0 (no) |
AR (1) | AR056279A1 (no) |
AU (1) | AU2006238976A1 (no) |
BR (1) | BRPI0606284A2 (no) |
CA (1) | CA2601600C (no) |
CR (1) | CR9436A (no) |
DO (1) | DOP2006000056A (no) |
EA (1) | EA012874B1 (no) |
GT (1) | GT200600116A (no) |
IL (1) | IL185997A0 (no) |
MA (1) | MA29336B1 (no) |
MX (1) | MX2007011423A (no) |
NL (1) | NL1031384C2 (no) |
NO (1) | NO20075209L (no) |
PE (1) | PE20061108A1 (no) |
TN (1) | TNSN07355A1 (no) |
TW (1) | TWI315670B (no) |
UA (1) | UA86873C2 (no) |
UY (1) | UY29418A1 (no) |
WO (1) | WO2006114666A1 (no) |
ZA (1) | ZA200707933B (no) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0525068D0 (en) | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
US8349852B2 (en) | 2009-01-13 | 2013-01-08 | Novartis Ag | Quinazolinone derivatives useful as vanilloid antagonists |
AU2010313392B2 (en) * | 2009-10-30 | 2015-07-09 | Janssen Pharmaceutica Nv | Pyrazines as delta opioid receptor modulators |
AR080055A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de los receptores de crf -1 |
AR080056A1 (es) | 2010-02-01 | 2012-03-07 | Novartis Ag | Derivados de ciclohexil-amida como antagonistas de los receptores de crf |
ES2527849T3 (es) | 2010-02-02 | 2015-01-30 | Novartis Ag | Derivados de ciclohexilamida como antagonistas del receptor de CRF |
JP2022062287A (ja) * | 2019-02-27 | 2022-04-20 | 住友化学株式会社 | ピリジルピラジン化合物の製造方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5880140A (en) * | 1996-04-03 | 1999-03-09 | Merck & Co., Inc. | Biheteroaryl inhibitors of farnesyl-protein transferase |
US5883105A (en) * | 1996-04-03 | 1999-03-16 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5872136A (en) * | 1996-04-03 | 1999-02-16 | Merck & Co., Inc. | Arylheteroaryl inhibitors of farnesyl-protein transferase |
PA8467401A1 (es) * | 1998-02-17 | 2000-09-29 | Pfizer Prod Inc | Procedimiento para tratar la insuficiencia cardiaca |
DE60039059D1 (de) * | 1999-10-07 | 2008-07-10 | Amgen Inc | Triazin-kinase-hemmer |
CO5271670A1 (es) * | 1999-10-29 | 2003-04-30 | Pfizer Prod Inc | Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas |
KR20080021603A (ko) * | 2000-02-16 | 2008-03-07 | 뉴로젠 코포레이션 | 치환된 아릴피라진 |
US6992087B2 (en) * | 2001-11-21 | 2006-01-31 | Pfizer Inc | Substituted aryl 1,4-pyrazine derivatives |
MXPA04004714A (es) * | 2001-11-21 | 2004-08-19 | Upjohn Co | Derivados de aril 1,4-pirazina sustituidos. |
WO2003091225A1 (en) * | 2002-04-26 | 2003-11-06 | Pharmacia & Upjohn Company | Substituted pyrazine derivatives |
WO2004024719A1 (en) * | 2002-09-12 | 2004-03-25 | Pharmacia & Upjohn Company Llc | Substituted 1,4-pyrazine derivatives |
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2006
- 2006-02-27 US US11/363,009 patent/US20060211710A1/en not_active Abandoned
- 2006-03-02 DO DO2006000056A patent/DOP2006000056A/es unknown
- 2006-03-06 KR KR1020077023701A patent/KR20070113294A/ko not_active Application Discontinuation
- 2006-03-06 WO PCT/IB2006/000564 patent/WO2006114666A1/en active Application Filing
- 2006-03-06 CA CA2601600A patent/CA2601600C/en not_active Expired - Fee Related
- 2006-03-06 EP EP06765409A patent/EP1871763A1/en not_active Withdrawn
- 2006-03-06 AP AP2007004174A patent/AP2007004174A0/xx unknown
- 2006-03-06 EA EA200701758A patent/EA012874B1/ru not_active IP Right Cessation
- 2006-03-06 UA UAA200710557A patent/UA86873C2/ru unknown
- 2006-03-06 MX MX2007011423A patent/MX2007011423A/es not_active Application Discontinuation
- 2006-03-06 AU AU2006238976A patent/AU2006238976A1/en not_active Abandoned
- 2006-03-06 JP JP2008501437A patent/JP2008533124A/ja not_active Ceased
- 2006-03-06 BR BRPI0606284-9A patent/BRPI0606284A2/pt not_active IP Right Cessation
- 2006-03-06 CN CNA2006800128070A patent/CN101160304A/zh active Pending
- 2006-03-13 UY UY29418A patent/UY29418A1/es not_active Application Discontinuation
- 2006-03-15 AR ARP060100986A patent/AR056279A1/es unknown
- 2006-03-15 PE PE2006000289A patent/PE20061108A1/es not_active Application Discontinuation
- 2006-03-16 GT GT200600116A patent/GT200600116A/es unknown
- 2006-03-16 TW TW095108969A patent/TWI315670B/zh not_active IP Right Cessation
- 2006-03-16 NL NL1031384A patent/NL1031384C2/nl not_active IP Right Cessation
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2007
- 2007-09-17 ZA ZA200707933A patent/ZA200707933B/xx unknown
- 2007-09-17 IL IL185997A patent/IL185997A0/en unknown
- 2007-09-17 MA MA30226A patent/MA29336B1/fr unknown
- 2007-09-17 TN TNP2007000355A patent/TNSN07355A1/fr unknown
- 2007-10-11 NO NO20075209A patent/NO20075209L/no not_active Application Discontinuation
- 2007-10-12 CR CR9436A patent/CR9436A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
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CR9436A (es) | 2007-11-23 |
ZA200707933B (en) | 2009-08-26 |
IL185997A0 (en) | 2008-01-20 |
EA200701758A1 (ru) | 2008-02-28 |
UA86873C2 (en) | 2009-05-25 |
AU2006238976A1 (en) | 2006-11-02 |
CN101160304A (zh) | 2008-04-09 |
KR20070113294A (ko) | 2007-11-28 |
MX2007011423A (es) | 2007-10-12 |
US20060211710A1 (en) | 2006-09-21 |
NL1031384C2 (nl) | 2007-01-23 |
WO2006114666A1 (en) | 2006-11-02 |
TW200700067A (en) | 2007-01-01 |
AP2007004174A0 (en) | 2007-10-31 |
WO2006114666A8 (en) | 2008-04-03 |
AR056279A1 (es) | 2007-10-03 |
PE20061108A1 (es) | 2006-10-13 |
JP2008533124A (ja) | 2008-08-21 |
EP1871763A1 (en) | 2008-01-02 |
DOP2006000056A (es) | 2006-08-30 |
BRPI0606284A2 (pt) | 2009-06-09 |
GT200600116A (es) | 2006-11-09 |
CA2601600A1 (en) | 2006-11-02 |
TNSN07355A1 (fr) | 2008-12-31 |
EA012874B1 (ru) | 2009-12-30 |
UY29418A1 (es) | 2006-10-31 |
CA2601600C (en) | 2010-09-14 |
MA29336B1 (fr) | 2008-03-03 |
TWI315670B (en) | 2009-10-11 |
NL1031384A1 (nl) | 2006-09-20 |
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