NO20073370L - Kombinasjoner som innbefatter epotiloner og proteintyrosinkinaseinhibitorer og farmasoytiske anvendelser derav - Google Patents

Kombinasjoner som innbefatter epotiloner og proteintyrosinkinaseinhibitorer og farmasoytiske anvendelser derav

Info

Publication number
NO20073370L
NO20073370L NO20073370A NO20073370A NO20073370L NO 20073370 L NO20073370 L NO 20073370L NO 20073370 A NO20073370 A NO 20073370A NO 20073370 A NO20073370 A NO 20073370A NO 20073370 L NO20073370 L NO 20073370L
Authority
NO
Norway
Prior art keywords
tyrosine kinase
protein tyrosine
kinase inhibitors
pharmaceutical applications
combinations including
Prior art date
Application number
NO20073370A
Other languages
English (en)
Inventor
Paul M J Mcsheehy
Jerry Min-Jian Huang
Anandhi Ranganathan Johri
Ronald Richard Linnartz
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36118322&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20073370(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20073370L publication Critical patent/NO20073370L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Abstract

Oppfinnelsen vedrører en kombinasjon som omfatter: (a) et epotilon; og (b) en proteintyrosinkinaseinhibitor; og eventuelt (c) et rapamycinderivat; for samtidig, separat eller sekvensiell bruk, i særdeleshet for progresjonsforsinkelse eller behandling av en proliferativ sykdom, spesielt kreft.
NO20073370A 2004-11-30 2007-06-29 Kombinasjoner som innbefatter epotiloner og proteintyrosinkinaseinhibitorer og farmasoytiske anvendelser derav NO20073370L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63183704P 2004-11-30 2004-11-30
PCT/US2005/042975 WO2006060331A1 (en) 2004-11-30 2005-11-28 Combinations comprising epothilones and protein tyrosine kinase inhibitors and pharmaceutical uses thereof

Publications (1)

Publication Number Publication Date
NO20073370L true NO20073370L (no) 2007-06-29

Family

ID=36118322

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073370A NO20073370L (no) 2004-11-30 2007-06-29 Kombinasjoner som innbefatter epotiloner og proteintyrosinkinaseinhibitorer og farmasoytiske anvendelser derav

Country Status (29)

Country Link
US (2) US20080139587A1 (no)
EP (1) EP1819331B1 (no)
JP (1) JP2008521826A (no)
KR (1) KR20070088653A (no)
CN (1) CN101065127A (no)
AT (1) ATE445398T1 (no)
AU (1) AU2005312061B2 (no)
BR (1) BRPI0518733A2 (no)
CA (1) CA2584163A1 (no)
CY (1) CY1110559T1 (no)
DE (1) DE602005017181D1 (no)
DK (1) DK1819331T3 (no)
ES (1) ES2333348T3 (no)
HK (1) HK1109059A1 (no)
HR (1) HRP20100012T1 (no)
IL (1) IL183138A (no)
JO (1) JO2596B1 (no)
MA (1) MA29032B1 (no)
MX (1) MX2007006371A (no)
NO (1) NO20073370L (no)
NZ (1) NZ554552A (no)
PL (1) PL1819331T3 (no)
PT (1) PT1819331E (no)
RU (1) RU2423980C2 (no)
SI (1) SI1819331T1 (no)
TN (1) TNSN07212A1 (no)
TW (1) TW200630091A (no)
WO (1) WO2006060331A1 (no)
ZA (1) ZA200703196B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011063421A1 (en) 2009-11-23 2011-05-26 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
US20110178287A1 (en) 2010-01-19 2011-07-21 Cerulean Pharma Inc. Cyclodextrin-based polymers for therapeutic delivery
CA2799202C (en) 2010-05-18 2016-07-05 Cerulean Pharma Inc. Compositions and methods for treatment of autoimmune and other diseases
CN102134246A (zh) * 2011-01-06 2011-07-27 王文怡 一种埃博霉素衍生物及其制备和药物应用
US20130178520A1 (en) 2011-12-23 2013-07-11 Duke University Methods of treatment using arylcyclopropylamine compounds
WO2014025395A1 (en) 2012-08-06 2014-02-13 Duke University Compounds and methods for targeting hsp90
WO2015148714A1 (en) 2014-03-25 2015-10-01 Duke University Heat shock protein 70 (hsp-70) receptor ligands
WO2017184956A1 (en) 2016-04-22 2017-10-26 Duke University Compounds and methods for targeting hsp90
US10207998B2 (en) 2016-09-29 2019-02-19 Duke University Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
US10927083B2 (en) 2016-09-29 2021-02-23 Duke University Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
EP3826988A4 (en) 2018-07-24 2023-03-22 Hygia Pharmaceuticals, LLC COMPOUNDS, DERIVATIVES AND ANALOGS AGAINST CANCER
WO2021233534A1 (en) 2020-05-20 2021-11-25 Pvac Medical Technologies Ltd Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
WO2021185844A1 (en) 2020-03-16 2021-09-23 Pvac Medical Technologies Ltd Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
JP2023536346A (ja) 2020-08-05 2023-08-24 エリプシーズ ファーマ リミテッド シクロデキストリン含有ポリマートポイソメラーゼ阻害剤コンジュゲートおよびｐａｒｐ阻害剤を用いた癌の処置
GB2617409A (en) 2022-04-27 2023-10-11 Cancertain Ltd Method for predicting responsiveness to therapy
WO2024030441A1 (en) 2022-08-02 2024-02-08 National University Corporation Hokkaido University Methods of improving cellular therapy with organelle complexes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2775187B1 (fr) * 1998-02-25 2003-02-21 Novartis Ag Utilisation de l'epothilone b pour la fabrication d'une preparation pharmaceutique antiproliferative et d'une composition comprenant l'epothilone b comme agent antiproliferatif in vivo
ATE369894T1 (de) * 2000-11-22 2007-09-15 Novartis Pharma Gmbh Kombination enthaltend ein mittel zur verminderung von vegf-aktivität und ein mittel zur verminderung von egf-aktivität
PL207197B1 (pl) * 2001-02-27 2010-11-30 Novartis Ag Połączenie obejmujące inhibitor przekazywania sygnału i pochodną epotylonową, kompozycja farmaceutyczna zawierająca to połączenie oraz zastosowanie połączenia
GB0119249D0 (en) * 2001-08-07 2001-10-03 Novartis Ag Organic compounds
NZ552335A (en) * 2001-10-25 2008-11-28 Novartis Ag Combinations comprising a selective COX-2 inhibitor and a microtubule interfering agent
CN1658904A (zh) * 2002-06-10 2005-08-24 诺瓦提斯公司 包含埃坡霉素的组合及其药学用途
US20060094674A1 (en) * 2002-07-05 2006-05-04 Neel Benjamin G Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms

Also Published As

Publication number Publication date
EP1819331A1 (en) 2007-08-22
HK1109059A1 (en) 2008-05-30
PL1819331T3 (pl) 2010-03-31
DK1819331T3 (da) 2010-01-04
TNSN07212A1 (en) 2008-11-21
AU2005312061A1 (en) 2006-06-08
HRP20100012T1 (hr) 2010-02-28
NZ554552A (en) 2011-05-27
MA29032B1 (fr) 2007-11-01
MX2007006371A (es) 2007-06-20
TW200630091A (en) 2006-09-01
AU2005312061B2 (en) 2009-09-03
ZA200703196B (en) 2009-08-26
CY1110559T1 (el) 2015-04-29
IL183138A (en) 2011-03-31
KR20070088653A (ko) 2007-08-29
US20080139587A1 (en) 2008-06-12
US20110190312A1 (en) 2011-08-04
BRPI0518733A2 (pt) 2008-12-02
CN101065127A (zh) 2007-10-31
RU2007124492A (ru) 2009-04-10
ATE445398T1 (de) 2009-10-15
SI1819331T1 (sl) 2010-02-26
WO2006060331A1 (en) 2006-06-08
PT1819331E (pt) 2009-11-30
JP2008521826A (ja) 2008-06-26
EP1819331B1 (en) 2009-10-14
JO2596B1 (en) 2011-02-27
ES2333348T3 (es) 2010-02-19
IL183138A0 (en) 2008-04-13
RU2423980C2 (ru) 2011-07-20
CA2584163A1 (en) 2006-06-08
DE602005017181D1 (de) 2009-11-26

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