NO20065907L - Nye tetrahydropyridotiofener - Google Patents

Nye tetrahydropyridotiofener

Info

Publication number
NO20065907L
NO20065907L NO20065907A NO20065907A NO20065907L NO 20065907 L NO20065907 L NO 20065907L NO 20065907 A NO20065907 A NO 20065907A NO 20065907 A NO20065907 A NO 20065907A NO 20065907 L NO20065907 L NO 20065907L
Authority
NO
Norway
Prior art keywords
tetrahydropyridothiophenes
new
compounds
proliferative
description
Prior art date
Application number
NO20065907A
Other languages
English (en)
Inventor
Thomas Beckers
Mathias Schmidt
Klaus Pekari
Thomas Bar
Bjorn Bartels
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of NO20065907L publication Critical patent/NO20065907L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Forbindelser med en bestemt formel I, hvor Ra og Rb har betydningene indikert i beskrivelsen, er nye effektive forbindelser med antiproliferativ og/eller apoptoseinduserende aktivitet
NO20065907A 2004-05-28 2006-12-19 Nye tetrahydropyridotiofener NO20065907L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04102413 2004-05-28
EP04104193 2004-09-01
PCT/EP2005/052384 WO2005118071A2 (en) 2004-05-28 2005-05-25 Tetrahydropyridothiophenes

Publications (1)

Publication Number Publication Date
NO20065907L true NO20065907L (no) 2006-12-19

Family

ID=35045196

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20065907A NO20065907L (no) 2004-05-28 2006-12-19 Nye tetrahydropyridotiofener

Country Status (25)

Country Link
US (2) US7723523B2 (no)
EP (1) EP1753512B1 (no)
JP (1) JP4881297B2 (no)
KR (1) KR20070037578A (no)
CN (1) CN1988934B (no)
AT (1) ATE400319T1 (no)
AU (1) AU2005249718B2 (no)
BR (1) BRPI0511461A (no)
CA (1) CA2567648A1 (no)
CY (1) CY1108399T1 (no)
DE (1) DE602005008050D1 (no)
DK (1) DK1753512T3 (no)
EA (1) EA012280B1 (no)
ES (1) ES2309765T3 (no)
HK (1) HK1106171A1 (no)
HR (1) HRP20080499T3 (no)
IL (1) IL178727A (no)
MX (1) MXPA06013383A (no)
NO (1) NO20065907L (no)
NZ (1) NZ550513A (no)
PL (1) PL1753512T3 (no)
PT (1) PT1753512E (no)
RS (1) RS50613B (no)
SI (1) SI1753512T1 (no)
WO (1) WO2005118071A2 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL1753512T3 (pl) 2004-05-28 2009-03-31 4Sc Ag Tetrahydropirydotiofeny
ES2308504T3 (es) 2004-06-04 2008-12-01 4Sc Ag Tetrahidropiridotiofenos para su utilizacion en el tratamiento del cancer.
US7714134B2 (en) 2004-06-11 2010-05-11 4Sc Ag Compounds and use of tetrahydropyridothiophenes
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
AU2006251167A1 (en) 2005-05-25 2006-11-30 4Sc Ag Tetrahydropyridothiophenes for use in the treatment of cancer
US20100285149A1 (en) * 2006-08-16 2010-11-11 Klaus Pekari Novel tetrahydropyridothiophenes
JP2010500396A (ja) * 2006-08-16 2010-01-07 ４エスツェー アクチェンゲゼルシャフト テトラヒドロベンゾチオフェン誘導体
TWI492759B (zh) 2008-03-05 2015-07-21 Otsuka Pharma Co Ltd 膽甾烷醇衍生物之併用用途
TW201005466A (en) * 2008-07-24 2010-02-01 Advanced Analog Technology Inc Low dropout regulator
EP2350093B1 (de) * 2008-10-24 2012-10-03 Grünenthal GmbH Substituierte 4,5,6,7-tetrahydrothienopyridine als kcnq2/3 modulatoren zur behandlung von schmerz, epilepsie und harninkontinenz
SI2404608T1 (sl) * 2009-03-04 2015-06-30 Otsuka Pharmaceutical Co., Ltd. Holestanolni derivat za kombinirano uporabo
CN104478850A (zh) * 2014-12-08 2015-04-01 上海应用技术学院 一种2-氨基噻吩-3甲酰胺的衍生物的制备方法

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JPS5498337A (en) * 1978-01-06 1979-08-03 Dai Ichi Seiyaku Co Ltd Anticarcinogenic and/or antimetastatic agent
DD272078A1 (de) 1986-04-15 1989-09-27 Dresden Arzneimittel Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten
DE4039734A1 (de) * 1990-12-13 1992-06-17 Basf Ag Substituierte 2-aminothiophene enthaltende herbizide mittel
GB9310700D0 (en) 1993-05-24 1993-07-07 Zeneca Ltd Novel composition
JP3074640B2 (ja) * 1995-12-22 2000-08-07 インターナショナル・ビジネス・マシーンズ・コーポレ−ション 液晶表示装置の駆動方法
GB9614718D0 (en) * 1996-07-12 1996-09-04 Bayer Ag 3-ureido-pyridofurans and -pyridothiophenes
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
AU2713599A (en) * 1998-03-12 1999-09-27 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
WO2000014090A1 (en) 1998-09-02 2000-03-16 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine derivatives
GB0114185D0 (en) 2001-06-12 2001-08-01 Protherics Molecular Design Lt Compounds
US7015328B2 (en) 2001-05-16 2006-03-21 Cytovia, Inc. Substituted coumarins and quinolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
US20040171603A1 (en) * 2001-05-18 2004-09-02 Janos Pato Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor
US20030232994A1 (en) * 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
MXPA04009283A (es) 2002-03-27 2005-01-25 Altana Pharma Ag Nuevos derivados de alcoxipiridina.
JP4103425B2 (ja) * 2002-03-28 2008-06-18 セイコーエプソン株式会社 電気光学装置、電子機器及び投射型表示装置
AU2003224054A1 (en) 2002-04-09 2003-10-20 Axxima Pharmaceuticals Ag 4,5,6,7-tretrahydrobenzo(b) thiophene derivatives and methods for medical intervention against mycrobacterial infections
US7012100B1 (en) 2002-06-04 2006-03-14 Avolix Pharmaceuticals, Inc. Cell migration inhibiting compositions and methods and compositions for treating cancer
CA2498399A1 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
JP2006503034A (ja) 2002-09-12 2006-01-26 メルク　エンド　カムパニー　インコーポレーテッド 置換二環式チオフェン誘導体、そのような化合物を含有する組成物、及び使用方法
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US7745630B2 (en) * 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
PL1753512T3 (pl) 2004-05-28 2009-03-31 4Sc Ag Tetrahydropirydotiofeny
ES2308504T3 (es) 2004-06-04 2008-12-01 4Sc Ag Tetrahidropiridotiofenos para su utilizacion en el tratamiento del cancer.
US7714134B2 (en) 2004-06-11 2010-05-11 4Sc Ag Compounds and use of tetrahydropyridothiophenes
SE0401970D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Novel compounds
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
AU2006212179A1 (en) 2005-02-11 2006-08-17 4Sc Ag Tetrahydropyridothiophenes as antripoliferative agents for the treatment of cancer
AU2006251167A1 (en) 2005-05-25 2006-11-30 4Sc Ag Tetrahydropyridothiophenes for use in the treatment of cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
JP2010500396A (ja) 2006-08-16 2010-01-07 ４エスツェー アクチェンゲゼルシャフト テトラヒドロベンゾチオフェン誘導体

Also Published As

Publication number Publication date
PL1753512T3 (pl) 2009-03-31
KR20070037578A (ko) 2007-04-05
CA2567648A1 (en) 2005-12-15
AU2005249718B2 (en) 2011-01-27
EP1753512A2 (en) 2007-02-21
HK1106171A1 (en) 2008-03-07
CY1108399T1 (el) 2014-02-12
PT1753512E (pt) 2008-10-14
DK1753512T3 (da) 2008-11-17
CN1988934A (zh) 2007-06-27
EP1753512B1 (en) 2008-07-09
DE602005008050D1 (de) 2008-08-21
AU2005249718A1 (en) 2005-12-15
BRPI0511461A (pt) 2007-12-26
SI1753512T1 (sl) 2008-12-31
ES2309765T3 (es) 2008-12-16
US7723523B2 (en) 2010-05-25
WO2005118071A2 (en) 2005-12-15
HRP20080499T3 (en) 2008-11-30
ATE400319T1 (de) 2008-07-15
US7803945B2 (en) 2010-09-28
EA200602157A1 (ru) 2007-06-29
IL178727A (en) 2010-12-30
IL178727A0 (en) 2007-02-11
JP2008500993A (ja) 2008-01-17
EA012280B1 (ru) 2009-08-28
JP4881297B2 (ja) 2012-02-22
US20070244112A1 (en) 2007-10-18
NZ550513A (en) 2009-10-30
RS50613B (sr) 2010-06-30
MXPA06013383A (es) 2007-01-23
WO2005118071A3 (en) 2006-06-01
US20090270378A1 (en) 2009-10-29
CN1988934B (zh) 2011-01-05

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Legal Events

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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application