NO20062758L - Polycykliske midler for behandling av respiratorisk syncytial virus infeksjoner - Google Patents

Polycykliske midler for behandling av respiratorisk syncytial virus infeksjoner

Info

Publication number
NO20062758L
NO20062758L NO20062758A NO20062758A NO20062758L NO 20062758 L NO20062758 L NO 20062758L NO 20062758 A NO20062758 A NO 20062758A NO 20062758 A NO20062758 A NO 20062758A NO 20062758 L NO20062758 L NO 20062758L
Authority
NO
Norway
Prior art keywords
treatment
respiratory syncytial
syncytial virus
virus infections
agents
Prior art date
Application number
NO20062758A
Other languages
English (en)
Inventor
John Lambert
Silas Bond
Vanessa Anne Sanford
Chin Yu Lim
Jeffrey Peter Mitchell
Alistair George Draffan
Roland Henry Nearn
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2003907196A external-priority patent/AU2003907196A0/en
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of NO20062758L publication Critical patent/NO20062758L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/424Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Forbindelser med formel (I) og anvendelse av dem ved behandling av infeksjoner som involverer virus av Pneumovirinae-subfamilien (RSV) er beskrevet. I formelen kan ring A være fenyl, pyridyl etc., B-C kan være CH2-CH2 etc., R1 kan være fenyl og substituerte former derav, R2 kan være forskjellige substituenter.
NO20062758A 2003-12-24 2006-06-13 Polycykliske midler for behandling av respiratorisk syncytial virus infeksjoner NO20062758L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003907196A AU2003907196A0 (en) 2003-12-24 Polycyclic agents for the treatment of respiratory syncytial virus infections
PCT/AU2004/001830 WO2005061513A1 (en) 2003-12-24 2004-12-24 Polycyclic agents for the treatment of respiratory syncytial virus infections

Publications (1)

Publication Number Publication Date
NO20062758L true NO20062758L (no) 2006-07-17

Family

ID=34705575

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062758A NO20062758L (no) 2003-12-24 2006-06-13 Polycykliske midler for behandling av respiratorisk syncytial virus infeksjoner

Country Status (17)

Country Link
US (2) US8598193B2 (no)
EP (2) EP2287167A1 (no)
JP (2) JP5384793B2 (no)
KR (1) KR20060127909A (no)
CN (2) CN101723949B (no)
AT (1) ATE496920T1 (no)
BR (1) BRPI0418127A (no)
CA (1) CA2551178C (no)
DE (1) DE602004031258D1 (no)
ES (1) ES2360222T3 (no)
HK (1) HK1088607A1 (no)
IL (1) IL176155A0 (no)
NO (1) NO20062758L (no)
NZ (1) NZ551468A (no)
RU (1) RU2422444C2 (no)
WO (1) WO2005061513A1 (no)
ZA (1) ZA200604528B (no)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0418127A (pt) 2003-12-24 2007-04-27 Biota Scient Management uso de um composto, seus sais, e derivados farmaceuticamente aceitáveis dos mesmos, método para o tratamento de infecções envolvendo vìrus da sub-famìlia pneumovirinae, formulação farmacêutica, métodos para tratar mamìferos infectados e para prevenir a infecção de mamìferos com vìrus da sub-famìlia pneumovirinae, composto, seus sais, e derivados farmaceuticamente aceitáveis dos mesmos, composto e a forma n-óxido e sal piridìnio do mesmo, e, método de separação de enantiÈmeros de um composto
AU2006329007A1 (en) * 2005-12-20 2007-06-28 Novartis Ag Nicotinic acid derivatives as modulators of metabotropic glutamate receptors
CN101506203B (zh) 2006-08-24 2013-10-16 诺瓦提斯公司 治疗代谢病、心血管病和其他病症的作为硬脂酰辅酶a脱饱和酶(scd)抑制剂的2-(吡嗪-2-基)-噻唑和2-(1h-吡唑-3-基)-噻唑衍生物及相关化合物
US8236835B2 (en) 2006-09-22 2012-08-07 Novartis Ag Heterocyclic inhibitors of stearoyl-CoA desaturase
TWI423972B (zh) * 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
CN101595105B (zh) 2006-12-20 2013-01-23 诺瓦提斯公司 作为scd抑制剂的2-取代的5元杂环化合物
TWI508968B (zh) 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物
PE20130395A1 (es) 2010-06-24 2013-04-10 Gilead Sciences Inc Pirazolo[1,5-a]pirimidinas para tratamiento antiviral
AU2015200638B2 (en) * 2010-06-24 2016-11-10 Gilead Sciences, Inc. Pyrazolo [1, 5 -a] pyrimidines as antiviral agents
US8796303B2 (en) 2010-11-26 2014-08-05 Biota Scientific Management Pty Ltd. Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections
US8871756B2 (en) * 2011-08-11 2014-10-28 Hoffmann-La Roche Inc. Compounds for the treatment and prophylaxis of Respiratory Syncytial Virus disease
BR112014008783A2 (pt) * 2011-10-11 2017-04-25 Hoffmann La Roche compostos para o tratamento e profilaxia da doença causada por vírus sincicial respiratório
CN103748098B (zh) * 2011-10-11 2016-06-29 弗·哈夫曼-拉罗切有限公司 用于治疗或预防呼吸道合胞病毒疾病的化合物
GB201119538D0 (en) 2011-11-10 2011-12-21 Viral Ltd Pharmaceutical compounds
ES2647486T3 (es) 2011-12-22 2017-12-21 Gilead Sciences, Inc. Pirazolo[1,5-a]pirimidinas como agentes antivirales
AU2013249280B2 (en) 2012-04-17 2017-10-12 Gilead Sciences, Inc. Compounds and methods for antiviral treatment
CN104311559A (zh) * 2014-09-12 2015-01-28 中山大学 一类光学纯手性环状n,n-缩醛的合成方法
US10118890B2 (en) 2014-10-10 2018-11-06 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration
WO2016133888A1 (en) * 2015-02-16 2016-08-25 Biota Pharmaceuticals, Inc. Compounds for treating respiratory syncytial virus infections
JO3637B1 (ar) 2015-04-28 2020-08-27 Janssen Sciences Ireland Uc مركبات بيرازولو- وترايازولو- بيريميدين مضادة للفيروسات rsv
CN107635999B (zh) 2015-05-20 2020-09-25 豪夫迈·罗氏有限公司 用于治疗脊髓性肌萎缩的化合物
WO2017009316A1 (en) 2015-07-16 2017-01-19 F. Hoffmann-La Roche Ag Crystalline forms of n-[(3-amino-3-oxetanyl)methyl]-2-(2,3-dihydro-1,1 -dioxido-1,4-benzothiazepin-4(5 h)-yl)-6-methyl-4-quinazolinamine for the treatment of respiratory syncytial virus (rsv) infections
EP3373972B1 (en) 2015-11-12 2024-03-20 F. Hoffmann-La Roche AG Compositions for treating spinal muscular atrophy
WO2017100726A1 (en) 2015-12-10 2017-06-15 Ptc Therapeutics, Inc. Methods for treatng huntington's disease
CN108137579B (zh) 2015-12-10 2022-01-07 豪夫迈·罗氏有限公司 桥连哌啶衍生物
CN109641042B (zh) * 2016-05-10 2023-06-09 乔治亚州立大学研究基金会股份有限公司 用于治疗rsv的杂环衍生物
CA3066224A1 (en) 2017-06-05 2018-12-13 Ptc Therapeutics Inc. Compounds for treating huntington's disease
MX2019014719A (es) 2017-06-14 2020-08-03 Virometix Ag Peptidos ciclicos para proteccion contra el virus sincitial respiratorio.
EP3645121A4 (en) 2017-06-28 2021-03-17 PTC Therapeutics, Inc. HUNTINGTON'S DISEASE TREATMENT METHODS
EP3644996B1 (en) 2017-06-28 2023-07-26 PTC Therapeutics, Inc. Methods for treating huntington's disease
TW201932470A (zh) 2017-11-29 2019-08-16 愛爾蘭商健生科學愛爾蘭無限公司 具有抗rsv活性之吡唑并嘧啶
MX2020008061A (es) 2018-01-31 2020-09-09 Janssen Sciences Ireland Unlimited Co Pirazolopirimidinas sustituidas con cicloalquilo que tienen actividad contra vrs.
US11760701B2 (en) 2018-02-27 2023-09-19 The Research Foundation For The State University Of New Yrok Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same
US20210009590A1 (en) 2018-03-27 2021-01-14 Ptc Therapeutics, Inc. Compounds for treating huntington's disease
CA3095277A1 (en) 2018-04-23 2019-10-31 Janssen Sciences Ireland Unlimited Company Heteroaromatic compounds having activity against rsv
EP3814357B1 (en) 2018-06-27 2024-05-01 PTC Therapeutics, Inc. Heterocyclic and heteroaryl compounds for treating huntington's disease
EP3814360A1 (en) 2018-06-27 2021-05-05 PTC Therapeutics, Inc. Heteroaryl compounds for treating huntington's disease
CN108997354B (zh) * 2018-08-08 2021-12-31 青岛大学附属医院 二氢嘧啶并异吲哚酮类化合物及其乳膏剂和在治疗高尿酸血症中的用途

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1058529A (en) 1910-12-24 1913-04-08 Harry T Hickey Car-door.
NL137586C (no) 1963-04-11
US3507863A (en) * 1963-12-18 1970-04-21 Sandoz Ag Isoindolones and method for preparing same
NL126596C (no) 1964-02-11
CH480350A (de) * 1965-09-21 1969-10-31 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
NL129866C (no) 1965-09-21
US3379733A (en) * 1965-12-07 1968-04-23 Sandoz Ag N-(omega-aminoalkyl)isoindoles and method for preparing same
CH481124A (de) 1966-09-21 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
DE1670041A1 (de) 1967-03-14 1972-03-02 American Home Prod Isoindole und Isoindoline
CH482697A (de) 1967-03-17 1969-12-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3935218A (en) * 1968-09-05 1976-01-27 American Home Products Corporation Imidazolinyl phenyl carbonyl compounds acid addition salts and related compounds
US3885037A (en) * 1968-09-05 1975-05-20 American Home Prod Method of producing anorexia using imidazolinyl phenyl carbonyl compounds, their acid addition salts and related compounds
US3657221A (en) * 1969-02-19 1972-04-18 American Home Prod Process for preparing 9b-substituted-1 - sulfonyl - 1 2 3 9b - tetrahydro-5h-imidazo(2 1-a)isoindol-5-ones
GB1322339A (en) 1970-03-10 1973-07-04 American Home Prod Imidazoline derivatives
US3624101A (en) * 1970-03-10 1971-11-30 American Home Prod 2,3-DIHYDRO-5-ARYL-5H-BENZ{8 f{9 IMIDAZO{8 2,1-a{9 ISOINDOL-5-OLS
US3770766A (en) * 1970-03-10 1973-11-06 American Home Prod 2-(2-amino-2,2-dialkylamino-3-hydroxy-3-phenyl-1h-benz(f)isoindole-1-ones
US3966955A (en) * 1974-08-07 1976-06-29 American Home Products Corporation Anti-ulcer therapy
US4056536A (en) * 1976-06-29 1977-11-01 Merck & Co., Inc. Pyrrolo[2,1-b][3]benzazepines
US4258529A (en) * 1978-07-21 1981-03-31 Phillips Petroleum Company Method of sealing a container
US4701208A (en) * 1983-08-02 1987-10-20 American Cyanamid Company Dihydroimidazopyrrolopyridine, quinoline, thieno- and furo[2,3-b]pyridine, dihydrothieno- and furo[2,3-b]-pyridine, thieno- and furo[3,2-b]pyridine and dihydrothieno- and furo[3,2-b]pyridine herbicides and method for preparation thereof
DE3520390A1 (de) * 1984-07-07 1986-02-06 Bayer Ag, 5090 Leverkusen Imidazo-pyrrolo-pyridin-derivate
EP0183993A3 (de) 1984-11-16 1987-12-09 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft 2H-Imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine und deren Verwendung als Unkrautbekämpfungsmittel
EP0195745B1 (de) * 1985-03-12 1990-09-12 Ciba-Geigy Ag Heterocyclisch kondensierte Pyridin-Verbindungen als Herbizide
DE3534948A1 (de) * 1985-10-01 1987-04-09 Bayer Ag Fungizide und wachstumsregulatorische mittel
US4717414A (en) * 1986-08-08 1988-01-05 Ppg Industries, Inc. Herbicidally active imidazopyrrolo-pyridine (or benzene) derivatives
DE3634952A1 (de) 1986-10-14 1988-04-21 Bayer Ag Imidazo-pyrrolo-pyridin-derivate
EP0475908A1 (de) * 1990-09-14 1992-03-18 Ciba-Geigy Ag Chromogene Lactamverbindungen und ihre Herstellung und Verwendung
DE4103177A1 (de) 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Thiazolo-(2,3-a)isoindol-derivate und diese enthaltende arzneimittel
EP0682523A1 (de) * 1991-02-28 1995-11-22 Roche Diagnostics GmbH Verwendung von trizyklischen isoindolinonen als antivirale arzneimittel und neue, optisch aktive isoindolinone
DE4108395A1 (de) * 1991-03-15 1993-01-28 Boehringer Mannheim Gmbh Verwendung von oxazolo-(2,3-a)isoindol-und imidazo(2,1-a)-isoindol-derivaten als antivirale arzneimittel sowie neue oxazolo(2,3-a)isoindol-derivaten
DE4129779A1 (de) * 1991-09-07 1993-03-11 Boehringer Mannheim Gmbh Neue tricyclische thiazol- und oxazol-derivate und diese enthaltende arzneimittel
ATE316089T1 (de) 1999-08-25 2006-02-15 Banyu Pharma Co Ltd Isoindolderivate
US6489338B2 (en) 2000-06-13 2002-12-03 Bristol-Myers Squibb Company Imidazopyridine and imidazopyrimidine antiviral agents
US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
AU2002223275A1 (en) 2000-11-22 2002-06-03 Biota Scientific Management Pty Ltd A method of expression and agents identified thereby
WO2002066479A1 (fr) * 2001-02-23 2002-08-29 Banyu Pharmaceutical Co.,Ltd. Derives de l'isoindole
JP2002310962A (ja) * 2001-04-19 2002-10-23 Hitachi Ltd 画像分類方法並びに観察方法及びその装置
AUPR878401A0 (en) 2001-11-09 2001-12-06 Biota Holdings Ltd Methods for identifying or screening anti-viral agents
BRPI0418127A (pt) 2003-12-24 2007-04-27 Biota Scient Management uso de um composto, seus sais, e derivados farmaceuticamente aceitáveis dos mesmos, método para o tratamento de infecções envolvendo vìrus da sub-famìlia pneumovirinae, formulação farmacêutica, métodos para tratar mamìferos infectados e para prevenir a infecção de mamìferos com vìrus da sub-famìlia pneumovirinae, composto, seus sais, e derivados farmaceuticamente aceitáveis dos mesmos, composto e a forma n-óxido e sal piridìnio do mesmo, e, método de separação de enantiÈmeros de um composto
DK3372281T3 (da) 2005-04-28 2021-09-27 Viiv Healthcare Co Polycyklisk carbamoylpyridon-derivat med HIV-integrase-hæmmende aktivitet
TWI423972B (zh) 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑

Also Published As

Publication number Publication date
ES2360222T3 (es) 2011-06-02
CA2551178A1 (en) 2005-07-07
ATE496920T1 (de) 2011-02-15
DE602004031258D1 (de) 2011-03-10
RU2006126663A (ru) 2008-01-27
US20070287700A1 (en) 2007-12-13
CN101723949B (zh) 2013-10-23
US8598193B2 (en) 2013-12-03
KR20060127909A (ko) 2006-12-13
RU2422444C2 (ru) 2011-06-27
CA2551178C (en) 2012-11-06
HK1088607A1 (en) 2006-11-10
JP5536842B2 (ja) 2014-07-02
JP2007516983A (ja) 2007-06-28
BRPI0418127A (pt) 2007-04-27
EP1697377A1 (en) 2006-09-06
EP1697377A4 (en) 2008-03-19
NZ551468A (en) 2010-05-28
CN100582109C (zh) 2010-01-20
EP2287167A1 (en) 2011-02-23
EP1697377B1 (en) 2011-01-26
CN1898247A (zh) 2007-01-17
IL176155A0 (en) 2006-10-05
ZA200604528B (en) 2007-06-27
WO2005061513A1 (en) 2005-07-07
CN101723949A (zh) 2010-06-09
JP2012246318A (ja) 2012-12-13
JP5384793B2 (ja) 2014-01-08
US20140051689A1 (en) 2014-02-20

Similar Documents

Publication Publication Date Title
NO20062758L (no) Polycykliske midler for behandling av respiratorisk syncytial virus infeksjoner
AP1753A (en) Thiophene derivatives as antiviral agents for flavvivirus infection
CY1112254T1 (el) Αρυλικοι φωσφοραμιδικοι εστερες νουκλεοζιτων και οι χρησεις τους ως αντι-ιικοι παραγοντες για την αντιμετωπιση του ιου της ηπατιτιδας c
DE602005023015D1 (de) Indolderivate als viruzide
CY1109183T1 (el) Συντηγμενες ετεροκυκλικες ενωσεις και χρηση αυτων ως αναστολεας hcv πολυμερασης
RS54260B1 (en) AMINODIHYDROTIAZINE DERIVATIVES AS BACE INHIBITORS FOR ALZHEIMER DISEASE TREATMENT
MX2007004979A (es) Derivados de indol tetraciclicos como agentes antiviricos.
BRPI0409938A (pt) derivados de azetidinacarboxamida e seu uso em terapia
DE60208364D1 (de) Chinolinderivate mit einer azolylgruppe und chinazolinderivate
ATE506354T1 (de) Substituierte arylcyclopropylacetamide als glucokinaseaktivatoren
AR056327A1 (es) Compuestos de nucleosidos para el tratamiento de infecciones virales
WO2006027628A3 (en) Naphthalimide derivatives as antiviral agents
CY1107008T1 (el) Παραγωγο βενζιμιδαζολης και χρηση ως ανταγωνιστου υποδοχεα aii
PE20090630A1 (es) Derivados de indol 2-carboxi sustituidos y metodos para su utilizacion
ATE523498T1 (de) Hiv-inhibierende 2-(4- cyanophenylamino)pyrimidinderivate
ECSP099506A (es) Derivados de 2-quinolinona y 2 quinoxalinona y su utilización como agentes anti bacterianos
NO20042010L (no) 4-imidazolin-2-on forbindelser
EA200700322A1 (ru) Оксазолидиноны, содержащие оксиндолы, в качестве антибактериальных агентов
WO2007092558A3 (en) Sulfonamide derivatives to treat infection with hepatitis c virus
ATE504583T1 (de) 4-imidazolin-2-onverbindungen
EA200401077A1 (ru) 2-оксазоламины и их применение в качестве антагонистов рецептора 5-ht2b
NO20075505L (no) 7-fluor-1,3-dihydro-indol-2-on oksazolidinoner som antibakterielle forbindelser
EA200701895A1 (ru) Оксиндол-оксазолидинон в качестве антибактериального агента
DK1406607T3 (da) Anvendelse af en klasse antivirale forbindelser til at fremstille et stof til at behandle eller forhindre en virusinfektion i luftvejene
TH83065B (th) อนุพันธ์เตตตระไซคลิค อินโดลที่เป็นสารต้านไวรัส

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application