NO20060554L - Fremgangsmate for fremstilling av C1-C15-fragmenter av epotiloner og derivater derav - Google Patents

Fremgangsmate for fremstilling av C1-C15-fragmenter av epotiloner og derivater derav

Info

Publication number
NO20060554L
NO20060554L NO20060554A NO20060554A NO20060554L NO 20060554 L NO20060554 L NO 20060554L NO 20060554 A NO20060554 A NO 20060554A NO 20060554 A NO20060554 A NO 20060554A NO 20060554 L NO20060554 L NO 20060554L
Authority
NO
Norway
Prior art keywords
fragments
epothilones
derivatives
fragment
preparing
Prior art date
Application number
NO20060554A
Other languages
English (en)
Norwegian (no)
Inventor
Ulrich Klar
Werner Skuballa
Wolfgang Schwede
Bernd Buchmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20060554L publication Critical patent/NO20060554L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/04—Saturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/17—Saturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
NO20060554A 2003-07-03 2006-02-02 Fremgangsmate for fremstilling av C1-C15-fragmenter av epotiloner og derivater derav NO20060554L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10331004A DE10331004A1 (de) 2003-07-03 2003-07-03 Verfahren für die Herstellung von C1-C15-Fragmenten von Epothilonen und deren Derivaten
PCT/EP2004/006685 WO2005003071A1 (de) 2003-07-03 2004-06-19 Verfahren für die herstellung von c1-c15-fragmenten von epothilonen und deren derivaten

Publications (1)

Publication Number Publication Date
NO20060554L true NO20060554L (no) 2006-04-03

Family

ID=33559999

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060554A NO20060554L (no) 2003-07-03 2006-02-02 Fremgangsmate for fremstilling av C1-C15-fragmenter av epotiloner og derivater derav

Country Status (17)

Country Link
US (1) US20070142675A1 (ja)
EP (1) EP1641734A1 (ja)
JP (1) JP2009513498A (ja)
KR (1) KR20060030102A (ja)
CN (2) CN101293819A (ja)
AU (1) AU2004254200A1 (ja)
BR (1) BRPI0412179A (ja)
CA (1) CA2531078A1 (ja)
CR (1) CR8128A (ja)
DE (1) DE10331004A1 (ja)
EA (1) EA200600149A1 (ja)
EC (1) ECSP066344A (ja)
IL (1) IL172936A0 (ja)
MX (1) MXPA06000172A (ja)
NO (1) NO20060554L (ja)
RS (1) RS20050973A (ja)
WO (1) WO2005003071A1 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8026081B2 (en) 2006-03-28 2011-09-27 Sumitomo Chemical Company, Limited Method of producing optically active (S)-7-hydroxy-6-methylheptan-2-one and precursor thereof
CN101519404B (zh) * 2008-02-29 2016-01-20 唐莉 15环噻酮衍生物及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5969145A (en) * 1996-08-30 1999-10-19 Novartis Ag Process for the production of epothilones and intermediate products within the process
US6204388B1 (en) * 1996-12-03 2001-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
DE69734362T2 (de) * 1996-12-03 2006-07-20 Sloan-Kettering Institute For Cancer Research Synthese von epothilonen, zwischenprodukte dazu, analoga und verwendungen davon
AU9340998A (en) * 1997-08-09 1999-03-01 Schering Aktiengesellschaft New epothilone derivatives, method for producing same and their pharmaceutical use
US7125893B1 (en) * 1999-04-30 2006-10-24 Schering Ag 6-alkenyl-, 6-alkinyl- and 6-epoxy-epothilone derivatives, process for their production, and their use in pharmaceutical preparations
US6518421B1 (en) * 2000-03-20 2003-02-11 Bristol-Myers Squibb Company Process for the preparation of epothilone analogs
US6593115B2 (en) * 2000-03-24 2003-07-15 Bristol-Myers Squibb Co. Preparation of epothilone intermediates
US6933385B2 (en) * 2001-08-03 2005-08-23 Schering Ag Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use
WO2003022844A2 (en) * 2001-09-06 2003-03-20 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones intermediates thereto and analogues thereof
DE10164592A1 (de) * 2001-12-21 2003-07-03 Schering Ag C1-C6-Epothilon-Fragmente und Verfahren für die Herstellung von C1-C6-Fragmenten von Epothilonen und deren Derivaten
EP1340498A1 (en) * 2002-03-01 2003-09-03 Schering Aktiengesellschaft Use of epothilones in the treatment of brain diseases associated with proliferative processes

Also Published As

Publication number Publication date
JP2009513498A (ja) 2009-04-02
MXPA06000172A (es) 2006-04-27
CR8128A (es) 2006-05-29
BRPI0412179A (pt) 2006-08-22
KR20060030102A (ko) 2006-04-07
DE10331004A1 (de) 2005-02-24
AU2004254200A1 (en) 2005-01-13
WO2005003071A1 (de) 2005-01-13
EA200600149A1 (ru) 2006-08-25
EP1641734A1 (de) 2006-04-05
IL172936A0 (en) 2006-06-11
ECSP066344A (es) 2006-08-30
RS20050973A (en) 2007-09-21
CN1816514A (zh) 2006-08-09
CN101293819A (zh) 2008-10-29
US20070142675A1 (en) 2007-06-21
CA2531078A1 (en) 2005-01-13
CN100480225C (zh) 2009-04-22

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application