NO20060464L - Use of CXCL6 chemokine in the prevention or repair of cartilage defects - Google Patents

Use of CXCL6 chemokine in the prevention or repair of cartilage defects

Info

Publication number
NO20060464L
NO20060464L NO20060464A NO20060464A NO20060464L NO 20060464 L NO20060464 L NO 20060464L NO 20060464 A NO20060464 A NO 20060464A NO 20060464 A NO20060464 A NO 20060464A NO 20060464 L NO20060464 L NO 20060464L
Authority
NO
Norway
Prior art keywords
repair
cxcl6
prevention
cartilage
cartilage defects
Prior art date
Application number
NO20060464A
Other languages
English (en)
Other versions
NO338152B1 (no
Inventor
Frank Luyten
Cosimo De Bari
Accio Francesco Dell
Original Assignee
Tigenix Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34135345&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20060464(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tigenix Nv filed Critical Tigenix Nv
Publication of NO20060464L publication Critical patent/NO20060464L/no
Publication of NO338152B1 publication Critical patent/NO338152B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Det beskrives ekspresjon av CXCL6 av celler som er i stand til å danne stabil brusk. Videre beskrives bruken av disse celler og av CXCL6 for å fremme brusk-(og underliggende ben-)dannelse, for eksempel ved reparasjon av bruskdefekter eller osteokondrale defekter. Oppfinnelsen beskriver videre bruken av kjemokiner ved modulering av progenitorcelledifferensiering.
NO20060464A 2003-08-12 2006-01-30 Anvendelsen av CXCL6 kjemokin ved prevensjon eller reparasjon av bruskdefekter NO338152B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49451603P 2003-08-12 2003-08-12
PCT/BE2004/000117 WO2005014026A2 (en) 2003-08-12 2004-08-12 Use of cxcl6 chemokine in the prevention or repair of cartilage defects

Publications (2)

Publication Number Publication Date
NO20060464L true NO20060464L (no) 2006-04-20
NO338152B1 NO338152B1 (no) 2016-08-01

Family

ID=34135345

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060464A NO338152B1 (no) 2003-08-12 2006-01-30 Anvendelsen av CXCL6 kjemokin ved prevensjon eller reparasjon av bruskdefekter

Country Status (16)

Country Link
US (2) US7485310B2 (no)
EP (1) EP1653994B1 (no)
JP (1) JP4920412B2 (no)
AT (1) ATE449608T1 (no)
AU (1) AU2004262451B2 (no)
CA (1) CA2533124C (no)
DE (1) DE602004024312D1 (no)
DK (1) DK1653994T3 (no)
ES (1) ES2337469T3 (no)
HK (1) HK1085656A1 (no)
IL (1) IL173544A (no)
NO (1) NO338152B1 (no)
NZ (1) NZ545702A (no)
PL (1) PL1653994T3 (no)
RU (1) RU2363491C2 (no)
WO (1) WO2005014026A2 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067123B2 (en) 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US20050222687A1 (en) * 2004-04-02 2005-10-06 Gordana Vunjak-Novakovic Cartilage implant assembly and method for implantation
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20090291112A1 (en) * 2003-05-16 2009-11-26 Truncale Katherine G Allograft osteochondral plug combined with cartilage particle mixture
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
US20090319045A1 (en) * 2004-10-12 2009-12-24 Truncale Katherine G Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US7815926B2 (en) 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
EP1926459B1 (en) 2005-09-19 2015-01-07 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
US8435551B2 (en) 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
EP2224884A2 (en) * 2007-12-05 2010-09-08 Musculoskeletal Transplant Foundation Cancellous bone implant for cartilage repair
CN102300880B (zh) 2008-09-22 2013-06-19 阿尔卡里奥斯有限责任公司 用作药物的羧基烷基环糊精多硫酸酯
GB0820492D0 (en) 2008-11-07 2008-12-17 Sportcell Cell compositions and uses thereof
EP2459224B1 (en) * 2009-07-27 2016-06-01 Baxalta GmbH Blood coagulation protein conjugates
CN102666840A (zh) * 2009-10-23 2012-09-12 Rnl生物技术株式会社 诱导脂肪源性成体干细胞迁移的方法
US8687070B2 (en) 2009-12-22 2014-04-01 Apple Inc. Image capture device having tilt and/or perspective correction
WO2014151459A1 (en) 2013-03-15 2014-09-25 W. L. Gore & Associates, Inc. Aqueous delivery system for low surface energy structures
CA2902226A1 (en) * 2013-03-29 2014-10-02 Merrimack Pharmaceuticals, Inc. Compositions and methods for treating osteolytic bone disorders
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CN116904520B (zh) * 2023-09-13 2024-01-09 中国人民解放军军事科学院军事医学研究院 制备重组软骨祖细胞的方法及获得的重组软骨祖细胞与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413511B1 (en) 1990-12-20 2002-07-02 University Of Pittsburgh Of The Commonwealth System Of Higher Education Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide
EP0804486B1 (en) * 1992-11-27 2008-10-01 Laboratoires Serono SA Granulocyte chemotactic protein
US5723331A (en) * 1994-05-05 1998-03-03 Genzyme Corporation Methods and compositions for the repair of articular cartilage defects in mammals
GB9502022D0 (en) 1995-02-02 1995-03-22 Abuljadayel Ilham M S A method for preparing lymphohaematopoietic progenitor cells
US6410268B1 (en) * 1996-03-18 2002-06-25 Human Genome Sciences, Inc. Polynucleotides encoding chemokine alpha-3
DE19814405C2 (de) * 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US6515001B2 (en) * 2001-03-05 2003-02-04 Chemokine Therapeutic Corporation IL-8 receptor ligands-drugs for inflammatory and autoimmune diseases
US20030224345A1 (en) * 2001-08-24 2003-12-04 Advanced Cell Technology Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy
EP1312614A1 (en) * 2001-11-16 2003-05-21 GenOdyssee Polynucleotides and polypeptides of the GCP-2 gene
JP2003199816A (ja) * 2002-01-10 2003-07-15 Takehisa Matsuda 軟骨組織再生用補助材、軟骨組織再生用キット及び軟骨組織再生方法
KR100855520B1 (ko) * 2002-07-26 2008-09-02 아지노모토 가부시키가이샤 신규 펩타이드 신타제 유전자
JP4950659B2 (ja) * 2003-06-27 2012-06-13 エチコン、インコーポレイテッド 胎盤組織から由来最多分娩後細胞、及びそれらを作成し使用する方法。

Also Published As

Publication number Publication date
EP1653994A2 (en) 2006-05-10
IL173544A (en) 2013-12-31
ES2337469T3 (es) 2010-04-26
US20060246031A1 (en) 2006-11-02
RU2363491C2 (ru) 2009-08-10
JP4920412B2 (ja) 2012-04-18
WO2005014026A2 (en) 2005-02-17
IL173544A0 (en) 2006-07-05
RU2006107536A (ru) 2006-08-10
NZ545702A (en) 2008-08-29
CA2533124C (en) 2014-01-28
WO2005014026A3 (en) 2005-03-17
DE602004024312D1 (de) 2010-01-07
US20090117652A1 (en) 2009-05-07
AU2004262451B2 (en) 2009-11-26
CA2533124A1 (en) 2005-02-17
JP2007501807A (ja) 2007-02-01
ATE449608T1 (de) 2009-12-15
AU2004262451A1 (en) 2005-02-17
US7842502B2 (en) 2010-11-30
EP1653994B1 (en) 2009-11-25
DK1653994T3 (da) 2010-03-15
PL1653994T3 (pl) 2010-05-31
HK1085656A1 (en) 2006-09-01
US7485310B2 (en) 2009-02-03
NO338152B1 (no) 2016-08-01

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