NO20055565L - Anvendelse av derivater av 2,4-dihydro-[1,2,4]triazol-3-thion som inhibitorer av enzymet myeloperoksidase (MPO) - Google Patents

Anvendelse av derivater av 2,4-dihydro-[1,2,4]triazol-3-thion som inhibitorer av enzymet myeloperoksidase (MPO)

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Publication number
NO20055565L
NO20055565L NO20055565A NO20055565A NO20055565L NO 20055565 L NO20055565 L NO 20055565L NO 20055565 A NO20055565 A NO 20055565A NO 20055565 A NO20055565 A NO 20055565A NO 20055565 L NO20055565 L NO 20055565L
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Prior art keywords
mpo
inhibitors
thione
triazol
dihydro
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NO20055565A
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English (en)
Other versions
NO20055565D0 (no
Inventor
Anna-Karin Tiden
Mats Svensson
Dominika Turek
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Astrazeneca Ab
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Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20055565D0 publication Critical patent/NO20055565D0/no
Publication of NO20055565L publication Critical patent/NO20055565L/no

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Abstract

Det er beskrevet anvendelsen av en forbindelse med formel (I) hvor X, Y, W og Q er som definert i beskrivelsen, og farmasøytisk akseptable salter derav, ved fremstilling av et medikament for behandling eller forebygging av sykdommer eller tilstander hvor inhibering av enzymet myeloperoksidase (MPO) er fordelaktig. Visse nye forbindelser med formel (I) og farmasøytisk akseptable salter derav er beskrevet, sammen med fremgangsmåter for deres fremstilling. Forbindelsene med formel (I) er MPO-inhibitorer og er derfor spesielt anvendelige ved behandling eller forebygging av neuroinflammatoriske lidelser.
NO20055565A 2003-04-25 2005-11-24 Anvendelse av derivater av 2,4-dihydro-[1,2,4]triazol-3-thion som inhibitorer av enzymet myeloperoksidase (MPO) NO20055565L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0301232A SE0301232D0 (sv) 2003-04-25 2003-04-25 Novel use
PCT/SE2004/000618 WO2004096781A1 (en) 2003-04-25 2004-04-22 Use of derivatives of 2, 4-dihydro-[1,2,4]triazole-3-thione as inhibitors o fteh enzyme myeloperoxidase (mpo)

Publications (2)

Publication Number Publication Date
NO20055565D0 NO20055565D0 (no) 2005-11-24
NO20055565L true NO20055565L (no) 2006-01-25

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ID=20291142

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NO20055565A NO20055565L (no) 2003-04-25 2005-11-24 Anvendelse av derivater av 2,4-dihydro-[1,2,4]triazol-3-thion som inhibitorer av enzymet myeloperoksidase (MPO)

Country Status (13)

Country Link
US (1) US20070093483A1 (no)
EP (1) EP1620410A1 (no)
JP (1) JP2006524686A (no)
KR (1) KR20060006064A (no)
CN (1) CN1780822A (no)
AU (1) AU2004234320A1 (no)
BR (1) BRPI0409498A (no)
CA (1) CA2523020A1 (no)
MX (1) MXPA05011207A (no)
NO (1) NO20055565L (no)
SE (1) SE0301232D0 (no)
WO (1) WO2004096781A1 (no)
ZA (1) ZA200508623B (no)

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KR20200083843A (ko) 2018-12-31 2020-07-09 공주대학교 산학협력단 4-(2-플루오로페닐)-3-(3-메톡시벤질)-1h-1,2,4-트리아졸-5(4h)-온 및 이의 퇴행성 뇌질환 및 대사성 질환 치료제로서의 용도
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JP2006522744A (ja) * 2003-04-11 2006-10-05 ノボ　ノルディスク　アクティーゼルスカブ グルココルチコイド受容体アゴニスト療法に伴う副作用を最小化するための、１１β−ヒドロキシステロイドデヒドロゲナーゼ１型阻害剤およびグルココルチコイド受容体アゴニストを使用する併用療法

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CN1780822A (zh) 2006-05-31
JP2006524686A (ja) 2006-11-02
EP1620410A1 (en) 2006-02-01
NO20055565D0 (no) 2005-11-24
WO2004096781A1 (en) 2004-11-11
BRPI0409498A (pt) 2006-05-02
AU2004234320A1 (en) 2004-11-11
US20070093483A1 (en) 2007-04-26
MXPA05011207A (es) 2005-12-14
KR20060006064A (ko) 2006-01-18
SE0301232D0 (sv) 2003-04-25
ZA200508623B (en) 2007-07-25

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