NO20053918L - Aminosyrer med affinitet for alfa-2-delta-proteinet. - Google Patents

Aminosyrer med affinitet for alfa-2-delta-proteinet.

Info

Publication number
NO20053918L
NO20053918L NO20053918A NO20053918A NO20053918L NO 20053918 L NO20053918 L NO 20053918L NO 20053918 A NO20053918 A NO 20053918A NO 20053918 A NO20053918 A NO 20053918A NO 20053918 L NO20053918 L NO 20053918L
Authority
NO
Norway
Prior art keywords
amino acids
affinity
alpha
delta protein
compounds
Prior art date
Application number
NO20053918A
Other languages
English (en)
Inventor
David Juergen Wustrow
Andrew John Thorpe
Nancy Sue Barta
Jacob Bradley Schwarz
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28675482&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20053918(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of NO20053918L publication Critical patent/NO20053918L/no
Application filed by Warner Lambert Co filed Critical Warner Lambert Co

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)

Abstract

Det beskrives visse ;5-aminosyrer som binder til a2^-subenheten av en kalsiumkanal. Forbindelsene og deres farmasøytisk akseptable salter finner anvendelse ved behandling av et antall psykiattiske, smerte- og andre hdelser. Forbindelsenes fremstilling og anvendelse beskrives.
NO20053918A 2002-03-28 2005-08-23 Aminosyrer med affinitet for alfa-2-delta-proteinet. NO20053918L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36841302P 2002-03-28 2002-03-28
PCT/IB2003/000976 WO2003082807A2 (en) 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein

Publications (1)

Publication Number Publication Date
NO20053918L true NO20053918L (no) 2004-12-01

Family

ID=28675482

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20044614A NO20044614L (no) 2002-03-28 2004-10-26 Aminosyrer med affinitet for alfa-2-delta-proteinet
NO20053918A NO20053918L (no) 2002-03-28 2005-08-23 Aminosyrer med affinitet for alfa-2-delta-proteinet.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20044614A NO20044614L (no) 2002-03-28 2004-10-26 Aminosyrer med affinitet for alfa-2-delta-proteinet

Country Status (43)

Country Link
US (3) US7064147B2 (no)
EP (2) EP1614675A3 (no)
JP (2) JP3831379B2 (no)
KR (2) KR100630981B1 (no)
CN (2) CN1817854A (no)
AP (1) AP1791A (no)
AR (2) AR039154A1 (no)
AU (1) AU2003208538B2 (no)
BR (1) BR0308814A (no)
CA (1) CA2480872C (no)
CR (1) CR7501A (no)
CU (1) CU23331B7 (no)
CY (1) CY1109304T1 (no)
DE (1) DE60328469D1 (no)
DK (1) DK1492761T3 (no)
EA (2) EA200501497A1 (no)
EC (1) ECSP045319A (no)
ES (1) ES2327910T3 (no)
GE (2) GEP20074123B (no)
GT (2) GT200300072A (no)
HK (1) HK1076627A1 (no)
HR (2) HRP20040891A2 (no)
IL (2) IL164110A0 (no)
IS (2) IS7451A (no)
MA (1) MA27188A1 (no)
MX (1) MXPA04009373A (no)
MY (1) MY131424A (no)
NI (1) NI200300043A (no)
NO (2) NO20044614L (no)
NZ (2) NZ535364A (no)
OA (1) OA12795A (no)
PA (1) PA8570001A1 (no)
PE (1) PE20040349A1 (no)
PL (1) PL209750B1 (no)
PT (1) PT1492761E (no)
RS (2) RS83604A (no)
SI (1) SI1492761T1 (no)
TN (1) TNSN04186A1 (no)
TW (1) TWI225864B (no)
UA (2) UA80116C2 (no)
UY (1) UY27738A1 (no)
WO (1) WO2003082807A2 (no)
ZA (1) ZA200407536B (no)

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DE10129693A1 (de) * 2001-06-22 2003-01-02 Jan Loock Verfahren zur extrakorporalen qualitativen und/oder quantitativen Erfassung neurotoxischer Substanzen im Blutplasma eines Individuums
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US7419981B2 (en) 2002-08-15 2008-09-02 Pfizer Inc. Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
EP1680125A1 (en) * 2003-07-02 2006-07-19 Warner-Lambert Company LLC Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
OA13258A (en) 2003-09-25 2007-01-31 Warner Lambert Co Amino acids with affinity for the alpha2delta-protein.
CN1856301A (zh) * 2003-09-25 2006-11-01 沃尼尔·朗伯有限责任公司 治疗性β－氨基酸
AU2005221401A1 (en) * 2004-03-12 2005-09-22 Warner-Lambert Company Llc C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin
EP1768952A2 (en) * 2004-07-09 2007-04-04 Warner-Lambert Company LLC Preparation of beta-amino acids having affinity for the alpha-2-delta protein
WO2006092692A1 (en) * 2005-03-01 2006-09-08 Pfizer Limited Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
AU2006226046A1 (en) * 2005-03-24 2006-09-28 Pharmacia & Upjohn Company Llc Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein
WO2007052134A1 (en) * 2005-11-04 2007-05-10 Pfizer Limited (2s)-2-aminomethyl-5-ethyl heptanoic acid its pharmaceutical use
JP2009516675A (ja) * 2005-11-17 2009-04-23 ファイザー・リミテッド 疼痛を治療するためのイソシステイン誘導体
US20090069427A1 (en) * 2006-03-06 2009-03-12 Pfizer Inc. Alpha-2-delta ligands for non-restorative sleep
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
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