NO2005011I2 - Frovatriptan - Google Patents

Frovatriptan

Info

Publication number
NO2005011I2
NO2005011I2 NO2005011C NO2005011C NO2005011I2 NO 2005011 I2 NO2005011 I2 NO 2005011I2 NO 2005011 C NO2005011 C NO 2005011C NO 2005011 C NO2005011 C NO 2005011C NO 2005011 I2 NO2005011 I2 NO 2005011I2
Authority
NO
Norway
Prior art keywords
frovatriptan
Prior art date
Application number
NO2005011C
Other languages
English (en)
Other versions
NO2005011I1 (no
Original Assignee
Vernalis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10697363&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2005011(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vernalis Ltd filed Critical Vernalis Ltd
Publication of NO2005011I1 publication Critical patent/NO2005011I1/no
Publication of NO2005011I2 publication Critical patent/NO2005011I2/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO2005011C 1991-06-26 2005-05-03 Frovatriptan NO2005011I2 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919113802A GB9113802D0 (en) 1991-06-26 1991-06-26 Medicaments
PCT/GB1992/001082 WO1993000086A1 (en) 1991-06-26 1992-06-17 Use of tetrahydrocarbazone derivatives as 5ht1 receptor agonists
US08/167,846 US5464864A (en) 1991-06-26 1992-06-17 Use of tetrahydrocarbazone derivatives as 5HT1 receptor agonists

Publications (2)

Publication Number Publication Date
NO2005011I1 NO2005011I1 (no) 2005-05-18
NO2005011I2 true NO2005011I2 (no) 2008-02-11

Family

ID=10697363

Family Applications (2)

Application Number Title Priority Date Filing Date
NO934759A NO304774B1 (no) 1991-06-26 1993-12-23 Tetrahydrokarbazolderivater, farmas÷ytiske blandinger inneholdende slike og anvendelse av disse derivater
NO2005011C NO2005011I2 (no) 1991-06-26 2005-05-03 Frovatriptan

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO934759A NO304774B1 (no) 1991-06-26 1993-12-23 Tetrahydrokarbazolderivater, farmas÷ytiske blandinger inneholdende slike og anvendelse av disse derivater

Country Status (35)

Country Link
US (2) US5464864A (no)
EP (1) EP0591280B1 (no)
JP (1) JP3261502B2 (no)
KR (1) KR100251571B1 (no)
CN (1) CN1034072C (no)
AP (1) AP344A (no)
AT (1) ATE170746T1 (no)
BR (2) BR9206237A (no)
CA (1) CA2113726C (no)
CZ (3) CZ282061B6 (no)
DE (2) DE69226953T2 (no)
DK (1) DK0591280T3 (no)
FI (1) FI103967B1 (no)
GB (1) GB9113802D0 (no)
HK (1) HK1014669A1 (no)
HU (1) HU218907B (no)
IE (1) IE922062A1 (no)
IL (4) IL117105A (no)
LU (1) LU90939I2 (no)
MA (1) MA22563A1 (no)
MX (1) MX9203444A (no)
NL (1) NL300103I2 (no)
NO (2) NO304774B1 (no)
NZ (1) NZ243288A (no)
PL (3) PL169392B1 (no)
PT (1) PT100620B (no)
RU (1) RU2137474C1 (no)
SA (1) SA92130141B1 (no)
SG (1) SG47877A1 (no)
SI (1) SI9200125B (no)
SK (3) SK280905B6 (no)
TW (1) TW214544B (no)
UA (1) UA41254C2 (no)
WO (1) WO1993000086A1 (no)
ZA (1) ZA924658B (no)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9226566D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
GB9226530D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
US5616603A (en) * 1995-05-26 1997-04-01 Smithkline Beecham Plc Enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5618948A (en) * 1995-05-26 1997-04-08 Smithkline Beecham P.L.C. Process for preparing an enantiomer of a carbazole derivative
ES2151993T3 (es) * 1995-06-23 2001-01-16 Lilly Co Eli 1,2,3,4-tetrahidro-9h-carbazoles 6-sustituidos y 10h-ciclohepta(7,6-b)indoles 7-sustituidos.
US5917054A (en) * 1995-07-18 1999-06-29 Smithkline Beecham P.L.C. Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists
US5708187A (en) * 1996-06-27 1998-01-13 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
US5891885A (en) * 1996-10-09 1999-04-06 Algos Pharmaceutical Corporation Method for treating migraine
GB9723061D0 (en) * 1997-10-31 1998-01-07 Vanguard Medica Ltd Medicaments
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6066092A (en) * 1997-11-06 2000-05-23 Cady; Roger K. Preemptive prophylaxis of migraine device and method
GB9808069D0 (en) * 1998-04-16 1998-06-17 Vanguard Medica Ltd Novel processes
GB9817911D0 (en) * 1998-08-17 1998-10-14 Vanguard Medica Ltd New use
US6685951B2 (en) 2001-07-05 2004-02-03 R. T. Alamo Ventures I, Inc. Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US20030198669A1 (en) * 2001-07-05 2003-10-23 R.T. Alamo Ventures I, Llc Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
US20030017175A1 (en) * 2001-07-05 2003-01-23 R.T. Alamo Ventures I, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
DK1537113T5 (da) 2002-06-21 2011-01-10 Suven Life Sciences Ltd Arylalkylindoler med serotoninreceptoraffinitet anvendelige som terapeutiske midler, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
CA2490254C (en) 2002-06-21 2011-11-01 Suven Life Sciences Limited Novel tetracyclic arylsulfonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
NZ572186A (en) 2002-11-28 2010-02-26 Suven Life Sciences Ltd N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them
BRPI0315958B8 (pt) 2002-11-28 2021-05-25 Suven Life Sciences Ltd composto, composição farmacêutica, processo para a preparação de um composto, novos intermediários e uso do composto
PT1581538E (pt) 2002-12-18 2007-05-31 Suven Life Sciences Ltd Indolos tetracíclicos substituidos na posição 3 que possuem afinidade pelo receptor de serotonina.
KR101411820B1 (ko) * 2006-08-07 2014-06-24 액테리온 파마슈티칼 리미티드 (3-아미노-1,2,3,4-테트라하이드로-9ｈ-카르바졸-9-일)-아세트산 유도체
JP2010522135A (ja) 2006-10-09 2010-07-01 チャールストン ラボラトリーズ，インコーポレイテッド 医薬組成物
EP2120875B1 (en) 2007-02-11 2018-07-11 Map Pharmaceuticals Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
US20090069399A1 (en) * 2007-09-12 2009-03-12 Protia, Llc Deuterium-enriched frovatriptan
JP5714910B2 (ja) 2008-01-09 2015-05-07 チャールストン ラボラトリーズ，インコーポレイテッド 薬学的組成物
WO2010073253A1 (en) * 2008-12-22 2010-07-01 Natco Pharma Limited Method for preparing an optically active frovatriptan
CA2767576C (en) 2009-07-08 2020-03-10 Charleston Laboratories Inc. Pharmaceutical compositions comprising an antiemetic and an opioid analgesic
US9204906B2 (en) 2009-10-22 2015-12-08 Nuvasive, Inc. Posterior cervical fusion system and techniques
US10098674B2 (en) 2009-10-22 2018-10-16 Nuvasive, Inc. System and method for posterior cervical fusion
WO2013016223A2 (en) 2011-07-22 2013-01-31 The University Of Chicago Treatments for migraine and related disorders
CA2895816C (en) 2012-12-21 2021-02-23 Map Pharmaceuticals, Inc. 8'-hydroxy-dihydroergotamine compounds and compositions
EP2816030A1 (en) 2013-06-20 2014-12-24 Duke Chem, S. A. Process for the preparation of frovatriptan and its enantiomer
GB201312768D0 (en) 2013-07-17 2013-08-28 Ge Healthcare Ltd Work-up procedure
US10179109B2 (en) 2016-03-04 2019-01-15 Charleston Laboratories, Inc. Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates
EP3766483A1 (en) 2019-07-19 2021-01-20 BioPharma Synergies, S. L. Orodispersible powder composition comprising a triptan

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3642816A (en) * 1967-08-10 1972-02-15 Sterling Drug Inc 3-acetamido-1 2 3 4-tetrahydrocarbazole
US4062864A (en) * 1968-01-24 1977-12-13 Sterling Drug Inc. 3-Hydroxy carbazole derivatives
US3959309A (en) * 1968-01-24 1976-05-25 Sterling Drug Inc. 3-Amido-1,2,3,4-tetrahydrocarbazoles
US3592824A (en) * 1970-03-12 1971-07-13 Miles Lab 3-substituted amino-1,2,3,4-tetrahydrocarbazoles
US4172834A (en) * 1971-08-16 1979-10-30 Sterling Drug Inc. 3-Amino-tetrahydrocarbazoles
BE787537A (fr) * 1971-08-16 1973-02-14 Sterling Drug Inc Tetrahydrocarbazoles
US4257952A (en) * 1977-06-06 1981-03-24 Sterling Drug Inc. 3-Amino-tetrahydrocarbazoles
US4254134A (en) * 1978-03-17 1981-03-03 Endo Laboratories, Inc. Antidepressant 2-amino- and -2-(substituted amino)-cis-hexahydro-carbazoles
EP0115607A1 (de) * 1983-01-04 1984-08-15 MERCK PATENT GmbH Tetrahydrocarbazolderivate

Also Published As

Publication number Publication date
JP3261502B2 (ja) 2002-03-04
AU652842B2 (en) 1994-09-08
RU2137474C1 (ru) 1999-09-20
CN1069726A (zh) 1993-03-10
CA2113726A1 (en) 1993-01-07
CZ150696A3 (en) 1997-06-11
NO934800L (no) 1993-12-23
CN1034072C (zh) 1997-02-19
NL300103I1 (nl) 2002-12-02
TW214544B (no) 1993-10-11
HU218907B (hu) 2000-12-28
KR100251571B1 (ko) 2000-07-01
MX9203444A (es) 1993-12-01
CA2113726C (en) 2008-02-19
NO934800D0 (no) 1993-12-23
FI935842A0 (fi) 1993-12-23
DK0591280T3 (da) 1999-02-15
SK280905B6 (sk) 2000-09-12
CZ282083B6 (cs) 1997-05-14
HUT68961A (en) 1995-08-28
CZ150596A3 (en) 1997-05-14
US5637611A (en) 1997-06-10
IL117105A (en) 1998-01-04
NO2005011I1 (no) 2005-05-18
EP0591280B1 (en) 1998-09-09
EP0591280A1 (en) 1994-04-13
NZ243288A (en) 1994-09-27
FI103967B (fi) 1999-10-29
PL169410B1 (pl) 1996-07-31
CZ282327B6 (cs) 1997-06-11
AP344A (en) 1994-07-05
AU1977592A (en) 1993-01-25
HK1014669A1 (en) 1999-09-30
US5464864A (en) 1995-11-07
CZ286193A3 (en) 1994-07-13
FI935842A (fi) 1993-12-23
IL102322A0 (en) 1993-01-14
SK280906B6 (sk) 2000-09-12
IL117104A (en) 1997-09-30
ATE170746T1 (de) 1998-09-15
BR1100460A (pt) 2000-07-18
IE922062A1 (en) 1992-12-30
DE69226953D1 (de) 1998-10-15
SG47877A1 (en) 1998-04-17
ZA924658B (en) 1993-12-24
IL102322A (en) 1997-09-30
FI103967B1 (fi) 1999-10-29
SK280907B6 (sk) 2000-09-12
SI9200125A (en) 1992-12-31
IL117104A0 (en) 1996-06-18
MA22563A1 (fr) 1992-12-31
IL117105A0 (en) 1996-06-18
NO304774B1 (no) 1999-02-15
JPH06508827A (ja) 1994-10-06
UA41254C2 (uk) 2001-09-17
NL300103I2 (nl) 2003-02-03
SI9200125B (en) 2001-12-31
PL171034B1 (en) 1997-02-28
GB9113802D0 (en) 1991-08-14
PL169392B1 (pl) 1996-07-31
BR9206237A (pt) 1995-04-11
CZ282061B6 (cs) 1997-05-14
DE10299042I2 (de) 2005-02-03
SK131993A3 (en) 1994-06-08
LU90939I2 (fr) 2002-09-24
PT100620B (pt) 1999-01-29
DE10299042I1 (de) 2003-02-20
WO1993000086A1 (en) 1993-01-07
AP9200403A0 (en) 1992-07-31
SA92130141B1 (ar) 2005-12-18
PT100620A (pt) 1993-09-30
DE69226953T2 (de) 1999-05-12

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