NO20030649D0 - Complexes Containing Polar Radical Perfluoroalkyl, Methods of Preparation and Use thereof - Google Patents

Complexes Containing Polar Radical Perfluoroalkyl, Methods of Preparation and Use thereof

Info

Publication number
NO20030649D0
NO20030649D0 NO20030649A NO20030649A NO20030649D0 NO 20030649 D0 NO20030649 D0 NO 20030649D0 NO 20030649 A NO20030649 A NO 20030649A NO 20030649 A NO20030649 A NO 20030649A NO 20030649 D0 NO20030649 D0 NO 20030649D0
Authority
NO
Norway
Prior art keywords
preparation
methods
complexes containing
containing polar
polar radical
Prior art date
Application number
NO20030649A
Other languages
Norwegian (no)
Other versions
NO20030649L (en
Inventor
Johannes Platzek
Peter Mareski
Ulrich Niedballa
Bernd Raduechel
Hanns-Joachim Weinmann
Bernd Misselwitz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20030649D0 publication Critical patent/NO20030649D0/en
Publication of NO20030649L publication Critical patent/NO20030649L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F19/00—Metal compounds according to more than one of main groups C07F1/00 - C07F17/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/103—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being acyclic, e.g. DTPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds
    • A61K49/101—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals
    • A61K49/106—Organic compounds the carrier being a complex-forming compound able to form MRI-active complexes with paramagnetic metals the complex-forming compound being cyclic, e.g. DOTA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20030649A 2000-08-11 2003-02-10 Complexes Containing Polar Radical Perfluoroalkyl, Methods of Preparation and Use thereof NO20030649L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10040858A DE10040858C2 (en) 2000-08-11 2000-08-11 Perfluoroalkyl-containing complexes with polar residues, process for their preparation and their use
PCT/EP2001/008500 WO2002013875A2 (en) 2000-08-11 2001-07-23 Complexes containing perfluoroalkyl with polar radicals, method for the production and use thereof

Publications (2)

Publication Number Publication Date
NO20030649D0 true NO20030649D0 (en) 2003-02-10
NO20030649L NO20030649L (en) 2003-04-11

Family

ID=7653176

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030649A NO20030649L (en) 2000-08-11 2003-02-10 Complexes Containing Polar Radical Perfluoroalkyl, Methods of Preparation and Use thereof

Country Status (30)

Country Link
EP (1) EP1307237B9 (en)
JP (1) JP2004506026A (en)
KR (2) KR20030022381A (en)
CN (1) CN1468113A (en)
AR (1) AR035342A1 (en)
AT (1) ATE359093T1 (en)
AU (2) AU7977701A (en)
BG (1) BG107541A (en)
BR (1) BR0113187A (en)
CA (1) CA2419259A1 (en)
CZ (1) CZ2003341A3 (en)
DE (2) DE10040858C2 (en)
DK (1) DK1307237T3 (en)
EE (1) EE200300060A (en)
ES (1) ES2284671T3 (en)
HR (1) HRP20030171A2 (en)
HU (1) HUP0300769A3 (en)
IL (1) IL154329A0 (en)
MX (1) MXPA03001286A (en)
NO (1) NO20030649L (en)
NZ (1) NZ524080A (en)
PL (1) PL365367A1 (en)
PT (1) PT1307237E (en)
RU (1) RU2289579C2 (en)
SK (1) SK286239B6 (en)
UA (1) UA74004C2 (en)
UY (1) UY26873A1 (en)
WO (1) WO2002013875A2 (en)
YU (1) YU10503A (en)
ZA (1) ZA200301947B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7344704B2 (en) 2002-07-10 2008-03-18 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
DE10231799B4 (en) * 2002-07-10 2006-10-05 Schering Ag Use of perfluoroalkyl-containing metal complexes as contrast agents in MR imaging for the presentation of intravascular thrombi
DE102005033903B4 (en) * 2005-07-15 2007-08-09 Bayer Schering Pharma Ag Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them
DE102005033902B3 (en) * 2005-07-15 2007-04-05 Schering Ag Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them
WO2007009637A2 (en) * 2005-07-15 2007-01-25 Bayer Schering Pharma Aktiengesellschaft Complexes containing perfluoroalkyl, their use as contrast media for nmr, x-ray and radio diagnosis and radiotherapy
DE102006049821A1 (en) 2006-10-18 2008-04-24 Bayer Schering Pharma Aktiengesellschaft New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues
DE102007015598A1 (en) * 2007-03-29 2008-10-02 Heinrich-Heine-Universität Düsseldorf Use of fluorochemical compounds for diagnostic purposes using imaging techniques
EP3101012A1 (en) 2015-06-04 2016-12-07 Bayer Pharma Aktiengesellschaft New gadolinium chelate compounds for use in magnetic resonance imaging
KR102464647B1 (en) 2016-11-28 2022-11-08 바이엘 파마 악티엔게젤샤프트 High Relaxation Gadolinium Chelate Compounds for Use in Magnetic Resonance Imaging
RU2681319C1 (en) * 2017-10-27 2019-03-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский экономический университет имени Г.В. Плеханова" (ФГБОУ ВО "РЭУ им. Г.В. Плеханова") Ultra-fibrous biopolymer material with bactericidal effect
BR112021007707A2 (en) 2018-11-23 2021-07-27 Bayer Aktiengesellschaft formulation of contrast media and its preparation process

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4317588C2 (en) * 1993-05-24 1998-04-16 Schering Ag Macrocyclic metal complexes containing fluorine, process for their preparation and their use
DE19603033A1 (en) * 1996-01-19 1997-07-24 Schering Ag Perfluoroalkyl-containing metal complexes, processes for their preparation and their use in NMR diagnostics
DE19608278A1 (en) * 1996-02-23 1997-08-28 Schering Ag Pharmaceutical compositions containing perfluoroalkyl-containing metal complexes, and their use in tumor therapy and interventional radiology
DE19729013A1 (en) * 1997-07-03 1999-02-04 Schering Ag Oligomeric, perfluoroalkyl-containing compounds, processes for their preparation and their use in NMR diagnostics
DE19744004C1 (en) * 1997-09-26 1999-07-22 Schering Ag Lipophilic metal complexes for necrosis and infarct imaging

Also Published As

Publication number Publication date
AR035342A1 (en) 2004-05-12
DK1307237T3 (en) 2007-07-02
SK1552003A3 (en) 2003-09-11
DE10040858A1 (en) 2002-03-28
UA74004C2 (en) 2005-10-17
KR20030022381A (en) 2003-03-15
BG107541A (en) 2004-01-30
NO20030649L (en) 2003-04-11
WO2002013875A2 (en) 2002-02-21
CZ2003341A3 (en) 2003-05-14
UY26873A1 (en) 2002-03-22
JP2004506026A (en) 2004-02-26
ATE359093T1 (en) 2007-05-15
EE200300060A (en) 2004-12-15
PT1307237E (en) 2007-07-02
DE50112336D1 (en) 2007-05-24
HUP0300769A2 (en) 2003-09-29
ES2284671T3 (en) 2007-11-16
YU10503A (en) 2006-08-17
CN1468113A (en) 2004-01-14
EP1307237A2 (en) 2003-05-07
EP1307237B9 (en) 2008-01-09
AU2001279777B2 (en) 2006-08-31
WO2002013875A3 (en) 2002-08-22
ZA200301947B (en) 2004-06-25
EP1307237B1 (en) 2007-04-11
DE10040858C2 (en) 2003-12-18
RU2289579C2 (en) 2006-12-20
CA2419259A1 (en) 2002-02-21
BR0113187A (en) 2003-07-01
NZ524080A (en) 2005-10-28
PL365367A1 (en) 2004-12-27
HUP0300769A3 (en) 2009-03-02
MXPA03001286A (en) 2004-04-20
AU7977701A (en) 2002-02-25
HRP20030171A2 (en) 2004-06-30
KR20080027397A (en) 2008-03-26
IL154329A0 (en) 2003-09-17
SK286239B6 (en) 2008-06-06

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