NO20022656D0 - Caspaseinhibitorer og anvendelse derav - Google Patents
Caspaseinhibitorer og anvendelse deravInfo
- Publication number
- NO20022656D0 NO20022656D0 NO20022656A NO20022656A NO20022656D0 NO 20022656 D0 NO20022656 D0 NO 20022656D0 NO 20022656 A NO20022656 A NO 20022656A NO 20022656 A NO20022656 A NO 20022656A NO 20022656 D0 NO20022656 D0 NO 20022656D0
- Authority
- NO
- Norway
- Prior art keywords
- caspase inhibitors
- caspase
- inhibitors
- Prior art date
Links
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- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
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Applications Claiming Priority (2)
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US16981299P | 1999-12-08 | 1999-12-08 | |
PCT/US2000/033260 WO2001042216A2 (en) | 1999-12-08 | 2000-12-08 | Caspase inhibitors and uses thereof |
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NO20022656D0 true NO20022656D0 (no) | 2002-06-05 |
NO20022656L NO20022656L (no) | 2002-08-06 |
NO324776B1 NO324776B1 (no) | 2007-12-10 |
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NO20022656A NO324776B1 (no) | 1999-12-08 | 2002-06-05 | Okso-2H-pyridin-, okso-2H-kinolin- og okso-1H-isokinolinderivater, deres fremstilling, farmasoytiske sammensetninger inneholdende dem og deres anvendelse |
NO20074773A NO20074773L (no) | 1999-12-08 | 2007-09-19 | Caspaseinhibitorer og anvendelse derav |
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NO20074773A NO20074773L (no) | 1999-12-08 | 2007-09-19 | Caspaseinhibitorer og anvendelse derav |
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US (4) | US7517987B2 (no) |
EP (4) | EP2308845A3 (no) |
JP (3) | JP5021131B2 (no) |
KR (3) | KR100904697B1 (no) |
CN (2) | CN100415718C (no) |
AP (1) | AP2002002535A0 (no) |
AR (1) | AR026748A1 (no) |
AU (3) | AU2428301A (no) |
BR (1) | BR0016282A (no) |
CA (2) | CA2733434A1 (no) |
CO (1) | CO5261609A1 (no) |
CZ (1) | CZ20021970A3 (no) |
EA (1) | EA200200645A1 (no) |
HU (1) | HUP0300782A3 (no) |
IL (1) | IL150077A0 (no) |
IS (1) | IS6411A (no) |
MX (1) | MXPA02005779A (no) |
NO (2) | NO324776B1 (no) |
NZ (2) | NZ519424A (no) |
PL (1) | PL356066A1 (no) |
SK (1) | SK8072002A3 (no) |
TW (1) | TWI275586B (no) |
WO (1) | WO2001042216A2 (no) |
ZA (1) | ZA200204390B (no) |
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EP2091947A2 (en) * | 2006-12-20 | 2009-08-26 | Takeda San Diego, Inc. | Glucokinase activators |
WO2008116107A2 (en) | 2007-03-21 | 2008-09-25 | Takeda San Diego, Inc. | Piperazine derivatives as glucokinase activators |
SG191591A1 (en) | 2008-05-21 | 2013-07-31 | New World Lab Inc | Selective caspase inhibitors and uses thereof |
US8518942B2 (en) * | 2008-08-06 | 2013-08-27 | Buck Institute For Research On Aging | Caspase inhibitors and uses thereof |
EP2344481B9 (en) * | 2008-09-23 | 2014-12-31 | Georgetown University | Viral and fungal inhibitors |
AU2009298888A1 (en) * | 2008-09-23 | 2010-04-08 | Georgetown University | 1,2-benzisothiazolinone and isoindolinone derivatives |
WO2010133000A1 (en) | 2009-05-21 | 2010-11-25 | New World Laboratories Inc. | Selective caspase inhibitors and uses thereof |
WO2010138585A1 (en) * | 2009-05-29 | 2010-12-02 | Merck Sharp & Dohme Corp. | Pyrimidinones as pde10 inhibitors |
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US9365612B2 (en) | 2010-01-29 | 2016-06-14 | United States Of America As Represented By The Secretary, Department Of Health And Human Services | Caspase inhibitors |
US20140309172A1 (en) | 2010-11-05 | 2014-10-16 | Dagmar Ringe | Ice inhibiting compounds and uses thereof |
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US9956260B1 (en) | 2011-07-22 | 2018-05-01 | The J. David Gladstone Institutes | Treatment of HIV-1 infection and AIDS |
CA2845551C (en) | 2011-08-16 | 2020-06-09 | Georgetown University | Methods of treating bacterial infections with 1,2-benzisothiazolinone and isoindolinone derivatives |
AU2014205043B2 (en) | 2013-01-14 | 2018-10-04 | Deuterx, Llc | 3-(5-substituted-4-oxoquinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives |
WO2014152833A1 (en) | 2013-03-14 | 2014-09-25 | Deuterx, Llc | 3-(substituted-4-oxo-quinazolin-3(4h)-yl)-3-deutero-piperidine-2,6-dione derivatives |
WO2014160592A2 (en) * | 2013-03-27 | 2014-10-02 | Merck Sharp & Dohme Corp. | FACTOR XIa INHIBITORS |
US9809603B1 (en) | 2015-08-18 | 2017-11-07 | Deuterx, Llc | Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4H)-yl-piperidinonyl conjugates and methods of treating medical disorders using same |
US11434212B2 (en) | 2017-01-23 | 2022-09-06 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Bicyclic compound as a caspase inhibitor |
CN106749045B (zh) * | 2017-03-03 | 2020-02-14 | 上海交通大学 | 一种d-氨基酸氧化酶抑制剂及其制法和应用 |
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EP4117642A4 (en) * | 2020-03-13 | 2024-05-15 | Univ Columbia | GPX4 COMPOUNDS AND COMPOSITIONS AND METHODS OF TREATMENT USING THEM |
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AR026748A1 (es) * | 1999-12-08 | 2003-02-26 | Vertex Pharma | Un compuesto inhibidor de caspasas, una composicion farmaceutica que lo comprende, un metodo para la sintesis del mismo y un compuesto intermediario paradicha sintesis |
AU2003211052A1 (en) * | 2002-02-11 | 2003-09-04 | Vertex Pharmaceuticals Incorporated | Phospholipids as caspase inhibitor prodrugs |
US7960398B2 (en) * | 2002-04-19 | 2011-06-14 | Vertex Pharmaceuticals Incorporated | Regulation of TNF-alpha |
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- 2000-12-07 CO CO00093694A patent/CO5261609A1/es not_active Application Discontinuation
- 2000-12-08 EP EP10196405A patent/EP2308845A3/en not_active Withdrawn
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- 2000-12-08 CN CNB008182558A patent/CN100415718C/zh not_active Expired - Fee Related
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- 2000-12-08 KR KR1020027007337A patent/KR100904697B1/ko not_active IP Right Cessation
- 2000-12-08 IL IL15007700A patent/IL150077A0/xx unknown
- 2000-12-08 SK SK807-2002A patent/SK8072002A3/sk not_active Application Discontinuation
- 2000-12-08 EP EP10196409A patent/EP2308846A3/en not_active Withdrawn
- 2000-12-08 WO PCT/US2000/033260 patent/WO2001042216A2/en active IP Right Grant
- 2000-12-08 CN CNA2008101443995A patent/CN101348455A/zh active Pending
- 2000-12-08 EP EP10196401A patent/EP2308844A3/en not_active Withdrawn
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- 2000-12-08 JP JP2001543517A patent/JP5021131B2/ja not_active Expired - Fee Related
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- 2000-12-08 BR BR0016282-5A patent/BR0016282A/pt not_active Application Discontinuation
- 2000-12-08 EA EA200200645A patent/EA200200645A1/ru unknown
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2002
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- 2002-06-05 NO NO20022656A patent/NO324776B1/no not_active IP Right Cessation
- 2002-06-06 IS IS6411A patent/IS6411A/is unknown
- 2002-06-10 US US10/166,437 patent/US7517987B2/en not_active Expired - Fee Related
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2006
- 2006-10-10 AU AU2006225317A patent/AU2006225317A1/en not_active Abandoned
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2007
- 2007-09-19 NO NO20074773A patent/NO20074773L/no not_active Application Discontinuation
- 2007-12-05 JP JP2007315252A patent/JP2008101019A/ja not_active Withdrawn
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2008
- 2008-02-18 KR KR1020087003852A patent/KR100910195B1/ko not_active IP Right Cessation
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2009
- 2009-01-26 US US12/359,749 patent/US7906650B2/en not_active Expired - Fee Related
- 2009-03-12 KR KR1020097005203A patent/KR100919654B1/ko not_active IP Right Cessation
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2010
- 2010-05-21 AU AU2010202075A patent/AU2010202075B2/en not_active Ceased
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2011
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- 2011-10-25 JP JP2011234386A patent/JP2012021032A/ja not_active Withdrawn
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