NO20020683D0 - Arylmetylkarbonylaminotiazolderivater og deres anvendelse som antitumormidler - Google Patents
Arylmetylkarbonylaminotiazolderivater og deres anvendelse som antitumormidlerInfo
- Publication number
- NO20020683D0 NO20020683D0 NO20020683A NO20020683A NO20020683D0 NO 20020683 D0 NO20020683 D0 NO 20020683D0 NO 20020683 A NO20020683 A NO 20020683A NO 20020683 A NO20020683 A NO 20020683A NO 20020683 D0 NO20020683 D0 NO 20020683D0
- Authority
- NO
- Norway
- Prior art keywords
- arylmethylcarbonylaminothiazole
- derivatives
- antitumor agents
- antitumor
- agents
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/372,832 US6114365A (en) | 1999-08-12 | 1999-08-12 | Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents |
PCT/IB2000/001423 WO2001014353A1 (en) | 1999-08-12 | 2000-08-11 | Arylmethyl-carbonylamino-thiazole derivatives and their use as antitumor agents |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20020683D0 true NO20020683D0 (no) | 2002-02-11 |
NO20020683L NO20020683L (no) | 2002-04-10 |
NO323576B1 NO323576B1 (no) | 2007-06-11 |
Family
ID=23469806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20020683A NO323576B1 (no) | 1999-08-12 | 2002-02-11 | Arylmetyl karbonylamino tiazolderivater og deres anvendelse for fremstilling av anttumormidler, fremgangsmate for fremstilling av disse forbindelsene og farmasoytisk preparat inneholdende forbindelsene. |
Country Status (36)
Country | Link |
---|---|
US (3) | US6114365A (no) |
EP (1) | EP1204649B1 (no) |
JP (1) | JP4864260B2 (no) |
KR (2) | KR100773709B1 (no) |
CN (1) | CN100410245C (no) |
AP (1) | AP1853A (no) |
AT (1) | ATE375987T1 (no) |
AU (1) | AU782882B2 (no) |
BG (1) | BG65484B1 (no) |
BR (1) | BR0013281A (no) |
CA (1) | CA2381097C (no) |
CY (1) | CY1107108T1 (no) |
CZ (1) | CZ303138B6 (no) |
DE (1) | DE60036803T2 (no) |
DK (1) | DK1204649T3 (no) |
EA (1) | EA005375B1 (no) |
EE (1) | EE04939B1 (no) |
ES (1) | ES2295056T3 (no) |
GE (1) | GEP20053475B (no) |
HK (1) | HK1054233B (no) |
HR (1) | HRP20020127B1 (no) |
HU (1) | HUP0202492A3 (no) |
IL (2) | IL147924A0 (no) |
IS (1) | IS2594B (no) |
MA (1) | MA25433A1 (no) |
MX (1) | MXPA02001508A (no) |
NO (1) | NO323576B1 (no) |
NZ (1) | NZ517236A (no) |
OA (1) | OA12047A (no) |
PT (1) | PT1204649E (no) |
RS (1) | RS50300B (no) |
SI (1) | SI1204649T1 (no) |
SK (1) | SK287373B6 (no) |
UA (1) | UA72538C2 (no) |
WO (1) | WO2001014353A1 (no) |
ZA (1) | ZA200201117B (no) |
Families Citing this family (66)
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US20020150921A1 (en) * | 1996-02-09 | 2002-10-17 | Francis Barany | Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays |
US6407103B2 (en) | 1998-04-21 | 2002-06-18 | Bristol-Myers Squibb Pharma Company | Indeno [1,2-c] pyrazol-4-ones and their uses |
US6610846B1 (en) * | 1999-03-29 | 2003-08-26 | Hoffman-La Roche Inc. | Heteroaromatic glucokinase activators |
US6320050B1 (en) * | 1999-03-29 | 2001-11-20 | Hoffmann-La Roche Inc. | Heteroaromatic glucokinase activators |
WO2000062778A1 (en) | 1999-04-15 | 2000-10-26 | Bristol-Myers Squibb Co. | Cyclic protein tyrosine kinase inhibitors |
US7125875B2 (en) * | 1999-04-15 | 2006-10-24 | Bristol-Myers Squibb Company | Cyclic protein tyrosine kinase inhibitors |
US6114365A (en) * | 1999-08-12 | 2000-09-05 | Pharmacia & Upjohn S.P.A. | Arylmethyl-carbonylamino-thiazole derivatives, process for their preparation, and their use as antitumor agents |
AU775373B2 (en) | 1999-10-01 | 2004-07-29 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
US20040048844A1 (en) * | 1999-10-20 | 2004-03-11 | Bristol-Myers Squibb Pharma Company | Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents |
US6291504B1 (en) | 1999-10-20 | 2001-09-18 | Dupont Pharmaceuticals Company | Acylsemicarbazides and their uses |
AU2002215053A1 (en) * | 2000-11-27 | 2002-06-24 | Pharmacia Italia S.P.A. | Phenylacetamido- pyrazole derivatives and their use as antitumor agents |
US6706718B2 (en) * | 2000-12-01 | 2004-03-16 | Bristol-Myers Squibb Company | 3-(2,4-dimethylthiazol-5-yl)indeno[1,2-c]pyrazol-4-one derivatives and their uses |
US6849631B2 (en) | 2000-12-08 | 2005-02-01 | Bristol Myers Squibb Pharma Company | Semicarbazides and their uses |
WO2002050071A1 (en) * | 2000-12-21 | 2002-06-27 | Bristol-Myers Squibb Company | Thiazolyl inhibitors of tec family tyrosine kinases |
DE60208630T2 (de) * | 2001-05-11 | 2006-08-17 | Pfizer Products Inc., Groton | Thiazolderivate und ihre Verwendung als cdk-Inhibitoren |
EP1724270A3 (en) | 2001-07-19 | 2007-01-03 | Pfizer Italia S.r.l. | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents |
CA2453294A1 (en) * | 2001-07-19 | 2003-01-30 | Paolo Pevarello | Phenylacetamido-thiazole derivatives, process for their preparation and their use as antitumor agents |
ATE440094T1 (de) * | 2001-09-27 | 2009-09-15 | Equispharm Co Ltd | Fumagillolderivate und verfahren zu deren herstellung |
US20030171411A1 (en) * | 2001-12-21 | 2003-09-11 | Kodra Janos Tibor | Amide derivatives as therapeutic agents |
KR101116627B1 (ko) * | 2002-06-27 | 2012-10-09 | 노보 노르디스크 에이/에스 | 치료제로서 아릴 카르보닐 유도체 |
WO2004072070A1 (en) * | 2003-02-12 | 2004-08-26 | Pfizer Inc. | Antiproliferative 2-(sulfo-phenyl)-aminothiazole derivatives |
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US20060229346A1 (en) * | 2003-03-31 | 2006-10-12 | Sucampo Ag | Method for treating vascular hyperpermeable disease |
WO2005014591A1 (en) * | 2003-07-15 | 2005-02-17 | L'oreal | 2-acylamino or 2-sulfonylamino-1, 3-thiazoles as couplers for the oxidation dyeing of keratin fibres |
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AU2003297904A1 (en) * | 2003-12-12 | 2005-07-14 | University Of Maryland, Baltimore | Immunomodulatory compounds that target and inhibit the py+3 binding site of tyrosene kinase p56 lck sh2 domain |
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UA103918C2 (en) * | 2009-03-02 | 2013-12-10 | Айерем Элелси | N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as wnt signaling modulators |
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DE102009043260A1 (de) * | 2009-09-28 | 2011-04-28 | Merck Patent Gmbh | Pyridinyl-imidazolonderivate |
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HU0900798D0 (en) | 2009-12-21 | 2010-03-01 | Vichem Chemie Kutato Kft | 4-phenylamino-pyrimidine derivatives having protein kinase inhibitor activity |
TWI450891B (zh) * | 2010-12-29 | 2014-09-01 | Dev Center Biotechnology | 新穎微管蛋白抑制劑 |
RU2011122942A (ru) | 2011-06-08 | 2012-12-20 | Общество С Ограниченной Ответственностью "Асинэкс Медхим" | Новые ингибиторы киназ |
CN103387551B (zh) * | 2012-05-11 | 2015-05-20 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻唑类化合物及其用途 |
EP2887943B1 (en) | 2012-08-23 | 2017-12-06 | Virostatics Srl | Novel 4,6-disubstituted aminopyrimidine derivatives |
JP6894923B2 (ja) | 2016-04-11 | 2021-06-30 | ジェンフィGenfit | 胆汁うっ滞性及び線維性の疾患の処置方法 |
CN111727042A (zh) | 2017-12-06 | 2020-09-29 | 仁新医药私人有限公司 | 微管蛋白抑制剂 |
WO2019148244A1 (en) * | 2018-02-01 | 2019-08-08 | The University Of Sydney | Anti-cancer compounds |
AU2019287437A1 (en) | 2018-06-12 | 2020-09-10 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
EP3712127A1 (en) | 2019-03-22 | 2020-09-23 | Deutsches Krebsforschungszentrum | Novel inhibitors of histone deacetylase 10 |
JP2022524887A (ja) | 2019-03-22 | 2022-05-10 | ドイチェス クレブスフォルシュングスツェントルム | ヒストンデアセチラーゼ10の新規の阻害剤 |
WO2021162054A1 (ja) * | 2020-02-10 | 2021-08-19 | 学校法人順天堂 | 2型リアノジン受容体活性抑制剤 |
CN115322208B (zh) * | 2021-05-10 | 2023-04-11 | 中国药科大学 | 2-氨基噻唑类衍生物及其制备方法和医药用途 |
WO2023182780A1 (ko) * | 2022-03-22 | 2023-09-28 | 오토텔릭바이오 주식회사 | 티아졸 유도체 화합물 및 이의 용도 |
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-
1999
- 1999-08-12 US US09/372,832 patent/US6114365A/en not_active Expired - Lifetime
-
2000
- 2000-08-11 US US10/048,474 patent/US6784198B1/en not_active Expired - Fee Related
- 2000-08-11 SK SK180-2002A patent/SK287373B6/sk not_active IP Right Cessation
- 2000-08-11 SI SI200030974T patent/SI1204649T1/sl unknown
- 2000-08-11 NZ NZ517236A patent/NZ517236A/en not_active IP Right Cessation
- 2000-08-11 MX MXPA02001508A patent/MXPA02001508A/es active IP Right Grant
- 2000-08-11 IL IL14792400A patent/IL147924A0/xx active IP Right Grant
- 2000-08-11 JP JP2001518441A patent/JP4864260B2/ja not_active Expired - Fee Related
- 2000-08-11 CZ CZ20020486A patent/CZ303138B6/cs not_active IP Right Cessation
- 2000-08-11 PT PT00962760T patent/PT1204649E/pt unknown
- 2000-08-11 AU AU74400/00A patent/AU782882B2/en not_active Ceased
- 2000-08-11 RS YUP-97/02A patent/RS50300B/sr unknown
- 2000-08-11 EA EA200200247A patent/EA005375B1/ru not_active IP Right Cessation
- 2000-08-11 EP EP00962760A patent/EP1204649B1/en not_active Expired - Lifetime
- 2000-08-11 DE DE60036803T patent/DE60036803T2/de not_active Expired - Lifetime
- 2000-08-11 HU HU0202492A patent/HUP0202492A3/hu unknown
- 2000-08-11 AP APAP/P/2002/002441A patent/AP1853A/en active
- 2000-08-11 KR KR1020027001844A patent/KR100773709B1/ko not_active IP Right Cessation
- 2000-08-11 GE GE4757A patent/GEP20053475B/en unknown
- 2000-08-11 BR BR0013281-0A patent/BR0013281A/pt not_active IP Right Cessation
- 2000-08-11 AT AT00962760T patent/ATE375987T1/de active
- 2000-08-11 WO PCT/IB2000/001423 patent/WO2001014353A1/en active IP Right Grant
- 2000-08-11 KR KR1020077014635A patent/KR100827563B1/ko not_active IP Right Cessation
- 2000-08-11 CA CA002381097A patent/CA2381097C/en not_active Expired - Fee Related
- 2000-08-11 OA OA1200200052A patent/OA12047A/en unknown
- 2000-08-11 ES ES00962760T patent/ES2295056T3/es not_active Expired - Lifetime
- 2000-08-11 CN CNB008127336A patent/CN100410245C/zh not_active Expired - Fee Related
- 2000-08-11 DK DK00962760T patent/DK1204649T3/da active
- 2000-08-11 EE EEP200200064A patent/EE04939B1/xx not_active IP Right Cessation
- 2000-11-08 UA UA2002031948A patent/UA72538C2/uk unknown
-
2002
- 2002-01-31 IL IL147924A patent/IL147924A/en not_active IP Right Cessation
- 2002-02-08 ZA ZA200201117A patent/ZA200201117B/en unknown
- 2002-02-11 NO NO20020683A patent/NO323576B1/no not_active IP Right Cessation
- 2002-02-11 IS IS6264A patent/IS2594B/is unknown
- 2002-02-12 HR HR20020127A patent/HRP20020127B1/xx not_active IP Right Cessation
- 2002-03-05 BG BG106481A patent/BG65484B1/bg unknown
- 2002-03-11 MA MA26547A patent/MA25433A1/fr unknown
-
2003
- 2003-09-11 HK HK03106484.7A patent/HK1054233B/zh not_active IP Right Cessation
-
2004
- 2004-07-29 US US10/902,326 patent/US20050004120A1/en not_active Abandoned
-
2007
- 2007-12-20 CY CY20071101629T patent/CY1107108T1/el unknown
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