NO20020668L - Ascididium derivatives and their therapeutic uses - Google Patents

Ascididium derivatives and their therapeutic uses

Info

Publication number
NO20020668L
NO20020668L NO20020668A NO20020668A NO20020668L NO 20020668 L NO20020668 L NO 20020668L NO 20020668 A NO20020668 A NO 20020668A NO 20020668 A NO20020668 A NO 20020668A NO 20020668 L NO20020668 L NO 20020668L
Authority
NO
Norway
Prior art keywords
ascididium
derivatives
therapeutic uses
compounds
antitumoral
Prior art date
Application number
NO20020668A
Other languages
Norwegian (no)
Other versions
NO20020668D0 (en
Inventor
Evelyne Delfourne
Francis Darro
Jean Bastide
Robert Kiss
Armand Frydman
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9910490A external-priority patent/FR2797445B1/en
Priority claimed from FR0006652A external-priority patent/FR2809399B1/en
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of NO20020668D0 publication Critical patent/NO20020668D0/en
Publication of NO20020668L publication Critical patent/NO20020668L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems

Abstract

The invention concerns a pharmaceutical composition comprising an efficient amount of a compound selected among the compounds of formulae (I) and (Ia) wherein: R1, R2, R3, R4, R5, R6 and R7 are as defined in Claim 1. Said compounds have interesting cytotoxic properties leading to a therapeutic use as antitumoral medicines.
NO20020668A 1999-08-13 2002-02-11 Ascididium derivatives and their therapeutic uses NO20020668L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9910490A FR2797445B1 (en) 1999-08-13 1999-08-13 ASCIDIDEMINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
FR0006652A FR2809399B1 (en) 2000-05-24 2000-05-24 NEW ASCIDIDEMINE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
PCT/FR2000/002312 WO2001012631A2 (en) 1999-08-13 2000-08-11 Ascididemin derivatives and their therapeutic applications

Publications (2)

Publication Number Publication Date
NO20020668D0 NO20020668D0 (en) 2002-02-11
NO20020668L true NO20020668L (en) 2002-04-15

Family

ID=26212422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020668A NO20020668L (en) 1999-08-13 2002-02-11 Ascididium derivatives and their therapeutic uses

Country Status (20)

Country Link
EP (1) EP1202992B1 (en)
JP (1) JP2003507381A (en)
CN (1) CN1195754C (en)
AT (1) ATE276256T1 (en)
AU (1) AU779932B2 (en)
BR (1) BR0013249A (en)
CA (1) CA2393965A1 (en)
CZ (1) CZ2002528A3 (en)
DE (1) DE60013849T2 (en)
DK (1) DK1202992T3 (en)
ES (1) ES2228602T3 (en)
HU (1) HUP0202767A3 (en)
IL (1) IL147900A0 (en)
MX (1) MXPA02001512A (en)
NO (1) NO20020668L (en)
NZ (1) NZ516896A (en)
PL (1) PL353453A1 (en)
PT (1) PT1202992E (en)
SK (1) SK1662002A3 (en)
WO (1) WO2001012631A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018104194A1 (en) * 2016-12-05 2018-06-14 Merck Patent Gmbh Materials for organic electroluminescent devices

Also Published As

Publication number Publication date
PL353453A1 (en) 2003-11-17
WO2001012631A2 (en) 2001-02-22
NO20020668D0 (en) 2002-02-11
CZ2002528A3 (en) 2002-05-15
NZ516896A (en) 2004-02-27
AU779932B2 (en) 2005-02-17
EP1202992A2 (en) 2002-05-08
MXPA02001512A (en) 2002-07-02
DE60013849D1 (en) 2004-10-21
CN1195754C (en) 2005-04-06
DK1202992T3 (en) 2005-01-24
HUP0202767A2 (en) 2003-01-28
PT1202992E (en) 2004-12-31
CA2393965A1 (en) 2001-02-22
EP1202992B1 (en) 2004-09-15
DE60013849T2 (en) 2005-02-03
AU7012400A (en) 2001-03-13
JP2003507381A (en) 2003-02-25
BR0013249A (en) 2002-04-16
CN1373762A (en) 2002-10-09
ES2228602T3 (en) 2005-04-16
HUP0202767A3 (en) 2003-12-29
WO2001012631A3 (en) 2001-07-19
SK1662002A3 (en) 2002-09-10
IL147900A0 (en) 2002-08-14
ATE276256T1 (en) 2004-10-15

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application