NO20015599L - Hjelpemidler eller preventive midler for sykdom assosiert med kjemokiner - Google Patents
Hjelpemidler eller preventive midler for sykdom assosiert med kjemokinerInfo
- Publication number
- NO20015599L NO20015599L NO20015599A NO20015599A NO20015599L NO 20015599 L NO20015599 L NO 20015599L NO 20015599 A NO20015599 A NO 20015599A NO 20015599 A NO20015599 A NO 20015599A NO 20015599 L NO20015599 L NO 20015599L
- Authority
- NO
- Norway
- Prior art keywords
- chemokines
- remedies
- preventive agents
- illness associated
- prophylactics
- Prior art date
Links
- 102000019034 Chemokines Human genes 0.000 title abstract 3
- 108010012236 Chemokines Proteins 0.000 title abstract 3
- 230000003449 preventive effect Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000000069 prophylactic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 abstract 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 abstract 1
- 101710151805 Mitochondrial intermediate peptidase 1 Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 cyclic amine Chemical class 0.000 abstract 1
- 201000008383 nephritis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/12—Nitrogen atoms not forming part of a nitro radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
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- A61K31/423—Oxazoles condensed with carbocyclic rings
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- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17585699 | 1999-05-18 | ||
JP25146499 | 1999-09-06 | ||
PCT/JP2000/003203 WO2000069432A1 (fr) | 1999-05-18 | 2000-05-18 | Moyens de traitement et de prevention contre les maladies associees a des chimiokines |
Publications (2)
Publication Number | Publication Date |
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NO20015599D0 NO20015599D0 (no) | 2001-11-16 |
NO20015599L true NO20015599L (no) | 2001-11-16 |
Family
ID=26496987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20015599A NO20015599L (no) | 1999-05-18 | 2001-11-16 | Hjelpemidler eller preventive midler for sykdom assosiert med kjemokiner |
Country Status (13)
Country | Link |
---|---|
US (1) | US7390830B1 (ko) |
EP (1) | EP1179341B1 (ko) |
KR (1) | KR100673340B1 (ko) |
CN (1) | CN1240699C (ko) |
AT (1) | ATE308985T1 (ko) |
AU (1) | AU779954B2 (ko) |
CA (1) | CA2373942A1 (ko) |
DE (1) | DE60023878T2 (ko) |
DK (1) | DK1179341T3 (ko) |
ES (1) | ES2250132T3 (ko) |
NO (1) | NO20015599L (ko) |
NZ (1) | NZ515374A (ko) |
WO (1) | WO2000069432A1 (ko) |
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CA2524534C (en) * | 2003-05-15 | 2012-12-11 | Sek Chung Fung | Methods and compositions for the prevention and treatment of sepsis |
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EP1524265A1 (en) * | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Prolinamide derivatives as sodium and/or calcium channel blockers or selective MAO-B inhibitors |
BRPI0417605B8 (pt) | 2003-12-18 | 2021-05-25 | Incyte Corp | n-[2-((3s)-3-{[4-hidróxi-4-(5-pirimidin-2- ilpiridin-2-il)ciclohexil]amino}-pirrolidin-1-il)-2- oxoetil]-3-(trifluor-metil)benzamida, ou um sal farmaceuticamente aceitável do mesmo e composição que o compreende. |
GB0401334D0 (en) * | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
US7884112B2 (en) | 2004-03-08 | 2011-02-08 | Stuart Edward Bradley | Pyrrolopyridine-2-carboxylic acid hydrazides |
JP2007537264A (ja) | 2004-05-11 | 2007-12-20 | インサイト コーポレイション | ケモカインレセプタのモジュレータとしての3−(4−ヘテロアリールシクロヘキシルアミノ)シクロペンタンカルボキサミド |
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MXPA06014262A (es) * | 2004-06-14 | 2007-03-12 | Teijin Pharma Ltd | Metodo para la produccion de derivado de acetamidopirrolidina y compuesto intermedio del mismo. |
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PT1942108E (pt) | 2005-10-28 | 2013-10-24 | Ono Pharmaceutical Co | Composto com um grupo básico e a sua utilização |
ES2407115T3 (es) | 2005-11-18 | 2013-06-11 | Ono Pharmaceutical Co., Ltd. | Compuesto que contiene un grupo básico y uso del mismo |
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EP2042503B1 (en) | 2006-05-16 | 2013-01-30 | Ono Pharmaceutical Co., Ltd. | Compound having acidic group which may be protected, and use thereof |
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JP2010505878A (ja) * | 2006-10-05 | 2010-02-25 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 線維症の処置のためのccr2アンタゴニスト |
WO2009104557A1 (ja) * | 2008-02-21 | 2009-08-27 | 株式会社カネカ | N-(3-ピロリジニル)グリシン誘導体の製造法 |
WO2010129351A1 (en) | 2009-04-28 | 2010-11-11 | Schepens Eye Research Institute | Method to identify and treat age-related macular degeneration |
KR101151415B1 (ko) | 2009-07-10 | 2012-06-01 | 양지화학 주식회사 | Ccr2 길항제로서의 피페라지닐에틸 3-아미노피롤리딘 유도체 |
US11033539B2 (en) * | 2015-11-06 | 2021-06-15 | Neurocrine Biosciences, Inc. | Compounds of formulas (VII), (VIII), (IX), (XI), (XII), (XIII), and (XIV) as muscarinic receptor 4(M4) antagonists for treating neurological diseases |
KR20190015492A (ko) * | 2016-06-08 | 2019-02-13 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 화학적 화합물 |
CN106916168B (zh) * | 2017-03-13 | 2019-08-27 | 牡丹江医学院 | 一种治疗重症胰腺炎的化合物及其制备方法 |
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IL125658A0 (en) | 1997-08-18 | 1999-04-11 | Hoffmann La Roche | Ccr-3 receptor antagonists |
BR9814645A (pt) | 1997-11-18 | 2001-07-31 | Teijin Ltd | Derivados de amina cìclica e seu uso como medicamentos |
DE19837485A1 (de) | 1998-08-12 | 2000-02-17 | Siemens Ag | Verfahren zum Erkennen von Schäden an Schienenfahrzeugen und/oder Gleisen |
CA2351631A1 (en) | 1998-11-20 | 2000-06-02 | F. Hoffmann-La Roche Ag | Piperidine quaternary salts-ccr-3 receptor antagonists |
JP3593037B2 (ja) | 1998-11-20 | 2004-11-24 | エフ.ホフマン−ラ ロシュ アーゲー | ピロリジン誘導体ccr−3受容体アンタゴニスト |
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WO2000069815A1 (en) * | 1999-05-13 | 2000-11-23 | Teijin Limited | Ureido-substituted cyclic amine derivatives and their use as drug |
AU779610B2 (en) | 1999-08-04 | 2005-02-03 | Teijin Limited | Cyclic amine CCR3 antagonists |
US6410566B1 (en) * | 2000-05-16 | 2002-06-25 | Teijin Limited | Cyclic amine derivatives and their use as drugs |
-
2000
- 2000-05-18 DK DK00927808T patent/DK1179341T3/da active
- 2000-05-18 AU AU46147/00A patent/AU779954B2/en not_active Ceased
- 2000-05-18 DE DE60023878T patent/DE60023878T2/de not_active Expired - Fee Related
- 2000-05-18 CN CNB008104905A patent/CN1240699C/zh not_active Expired - Fee Related
- 2000-05-18 AT AT00927808T patent/ATE308985T1/de not_active IP Right Cessation
- 2000-05-18 CA CA002373942A patent/CA2373942A1/en not_active Abandoned
- 2000-05-18 WO PCT/JP2000/003203 patent/WO2000069432A1/ja active Search and Examination
- 2000-05-18 EP EP00927808A patent/EP1179341B1/en not_active Expired - Lifetime
- 2000-05-18 NZ NZ515374A patent/NZ515374A/en unknown
- 2000-05-18 ES ES00927808T patent/ES2250132T3/es not_active Expired - Lifetime
- 2000-05-18 US US09/959,635 patent/US7390830B1/en not_active Expired - Fee Related
- 2000-05-18 KR KR1020017014579A patent/KR100673340B1/ko not_active IP Right Cessation
-
2001
- 2001-11-16 NO NO20015599A patent/NO20015599L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1384743A (zh) | 2002-12-11 |
DE60023878D1 (de) | 2005-12-15 |
KR20020015322A (ko) | 2002-02-27 |
ATE308985T1 (de) | 2005-11-15 |
NO20015599D0 (no) | 2001-11-16 |
EP1179341A1 (en) | 2002-02-13 |
WO2000069432A1 (fr) | 2000-11-23 |
US7390830B1 (en) | 2008-06-24 |
AU779954B2 (en) | 2005-02-24 |
CN1240699C (zh) | 2006-02-08 |
DE60023878T2 (de) | 2006-07-20 |
ES2250132T3 (es) | 2006-04-16 |
KR100673340B1 (ko) | 2007-02-28 |
AU4614700A (en) | 2000-12-05 |
CA2373942A1 (en) | 2000-11-23 |
NZ515374A (en) | 2004-09-24 |
EP1179341B1 (en) | 2005-11-09 |
DK1179341T3 (da) | 2006-03-27 |
EP1179341A4 (en) | 2003-10-29 |
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