NO20013560L - Polymorphs of telmisartan, methods of preparation thereof and use thereof for the manufacture of a drug - Google Patents

Polymorphs of telmisartan, methods of preparation thereof and use thereof for the manufacture of a drug

Info

Publication number
NO20013560L
NO20013560L NO20013560A NO20013560A NO20013560L NO 20013560 L NO20013560 L NO 20013560L NO 20013560 A NO20013560 A NO 20013560A NO 20013560 A NO20013560 A NO 20013560A NO 20013560 L NO20013560 L NO 20013560L
Authority
NO
Norway
Prior art keywords
telmisartan
polymorphs
drug
manufacture
preparation
Prior art date
Application number
NO20013560A
Other languages
Norwegian (no)
Other versions
NO319823B1 (en
NO20013560D0 (en
Inventor
Heinric Schneider
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO20013560D0 publication Critical patent/NO20013560D0/en
Publication of NO20013560L publication Critical patent/NO20013560L/en
Publication of NO319823B1 publication Critical patent/NO319823B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/20—Two benzimidazolyl-2 radicals linked together directly or via a hydrocarbon or substituted hydrocarbon radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
NO20013560A 1999-01-19 2001-07-18 Polymorphs of telmisartan, processes for their preparation and their use for the preparation of a drug NO319823B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19901921A DE19901921C2 (en) 1999-01-19 1999-01-19 Polymorphs of telmisartan, process for their preparation and their use in the manufacture of a medicament
PCT/EP2000/000065 WO2000043370A1 (en) 1999-01-19 2000-01-07 Telmisartan polymorphs, methods for producing same and their use in the preparation of a medicament

Publications (3)

Publication Number Publication Date
NO20013560D0 NO20013560D0 (en) 2001-07-18
NO20013560L true NO20013560L (en) 2001-09-18
NO319823B1 NO319823B1 (en) 2005-09-19

Family

ID=7894715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013560A NO319823B1 (en) 1999-01-19 2001-07-18 Polymorphs of telmisartan, processes for their preparation and their use for the preparation of a drug

Country Status (36)

Country Link
EP (1) EP1144386B1 (en)
JP (1) JP4700813B2 (en)
KR (1) KR100658959B1 (en)
CN (1) CN1144790C (en)
AR (1) AR035475A1 (en)
AT (1) ATE252564T1 (en)
AU (1) AU765081B2 (en)
BG (1) BG65027B1 (en)
BR (1) BR0007584A (en)
CA (1) CA2352436C (en)
CO (1) CO5150238A1 (en)
CZ (1) CZ297412B6 (en)
DE (2) DE19901921C2 (en)
DK (1) DK1144386T3 (en)
EA (1) EA003065B1 (en)
EE (1) EE04344B1 (en)
ES (1) ES2208265T3 (en)
HK (1) HK1041485B (en)
HR (1) HRP20010514B1 (en)
HU (1) HU227401B1 (en)
IL (2) IL143634A0 (en)
MY (1) MY122755A (en)
NO (1) NO319823B1 (en)
NZ (1) NZ513528A (en)
PE (1) PE20001362A1 (en)
PL (1) PL211829B1 (en)
PT (1) PT1144386E (en)
RS (1) RS50044B (en)
SA (1) SA99200838B1 (en)
SK (1) SK285429B6 (en)
TR (1) TR200102074T2 (en)
TW (1) TWI280241B (en)
UA (1) UA56358C2 (en)
UY (1) UY25980A1 (en)
WO (1) WO2000043370A1 (en)
ZA (1) ZA200104771B (en)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10153737A1 (en) * 2001-10-31 2003-05-28 Boehringer Ingelheim Pharma Crystalline sodium salt of telmisartan, process for its preparation and its use for the manufacture of a medicament
US6737432B2 (en) 2001-10-31 2004-05-18 Boehringer Ingelheim Pharma Kg Crystalline form of telmisartan sodium
CZ303145B6 (en) 2002-01-16 2012-05-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for preparing bilayer pharmaceutical tablet containing telmisartan and hydrochlorothiazide
DE10314702A1 (en) 2003-03-31 2004-10-21 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for the preparation of telmisartan
GB2414019A (en) * 2004-05-11 2005-11-16 Cipla Ltd One-step preparation of telmisartan by condensation and hydrolysis
WO2006044648A1 (en) 2004-10-15 2006-04-27 Teva Pharmaceutical Industries Ltd. Process for preparing telmisartan
WO2006044754A2 (en) 2004-10-18 2006-04-27 Dr. Reddy's Laboratories Ltd. Process for preparing telmisartan
US8637078B2 (en) 2005-11-24 2014-01-28 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and diuretic
EP1908469A1 (en) 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
DE102008059206A1 (en) 2008-11-27 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Pharmaceutical dosage form containing nifedipine or nisoldipine and an angiotensin II antagonist and / or a diuretic
BRPI1013037A2 (en) 2009-05-20 2019-09-24 Boehringer Ingelheim Ipharmaceuticals Inc "telmisartan oral pharmaceutical solution"
EP2443094B1 (en) 2009-06-19 2013-03-20 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of telmisartan
EP2277866A1 (en) 2009-06-22 2011-01-26 Inke, S.A. Process for preparing telmisartan
WO2011002423A2 (en) 2009-07-02 2011-01-06 Mahmut Bilgic Solubility enhancing pharmaceutical composition
EP2448575A2 (en) 2009-07-02 2012-05-09 Bilgic Mahmut Pharmaceutical composition increasing solubility and stability
WO2012055941A1 (en) 2010-10-27 2012-05-03 Krka,Tovarna Zdravil, D. D., Novo Mesto Multilayer pharmaceutical composition comprising telmisartan and amlodipine
ITMI20102416A1 (en) * 2010-12-27 2012-06-28 Chemelectiva S R L INTERMEDIATE FOR THE PREPARATION OF AN ACTIVE PRINCIPLE AND PROCESS FOR ITS PREPARATION
EP2612658A1 (en) 2012-01-05 2013-07-10 Laboratorios Lesvi, S.L. Pharmaceutical compositions of 4'-[(1,4'dimethyl-2'-propyl[2,6'-bi-1h-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid and is 6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
JP6147546B2 (en) * 2013-04-10 2017-06-14 株式会社トクヤマ Method for producing telmisartan A-type crystals with reduced acetic acid
EP2979691A1 (en) 2014-07-30 2016-02-03 Boehringer Ingelheim International GmbH Oral disintegrating tablet
JP6275596B2 (en) * 2014-09-03 2018-02-07 株式会社トクヤマ Method for producing ammonium salt of telmisartan
JP5871294B1 (en) 2015-02-27 2016-03-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Immediate release oral tablets
KR20170001921A (en) 2015-06-26 2017-01-05 대원제약주식회사 A pharmaceutical composition comprising telmisartan with increased stability and a preparation method thereof
KR20170012703A (en) 2015-07-22 2017-02-03 대원제약주식회사 A pharmaceutical composition comprising telmisartan and a preparation method thereof
EP3463309B1 (en) 2016-05-30 2020-06-17 Boehringer Ingelheim International GmbH Fixed dose combination of telmisartan, hydrochlorothiazide and amlodipine
KR102044223B1 (en) * 2016-09-12 2019-11-13 성균관대학교산학협력단 Solid dispersions comprising Telmisartan and the preparation method thereof
CN106749036B (en) * 2016-12-21 2019-06-21 山东大学 A kind of unformed Telmisartan-pimelic acid eutectic and its preparation method and application
CN106749037B (en) * 2016-12-21 2019-06-21 山东大学 A kind of unformed Telmisartan-glutaric acid eutectic and its preparation method and application
US10905676B2 (en) 2017-07-07 2021-02-02 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II receptor antagonist for the prevention or treatment of systemic diseases in cats
CN109851562A (en) * 2019-01-30 2019-06-07 浙江省食品药品检验研究院 A kind of Telmisartan crystal and preparation method thereof
EP4373474A1 (en) 2021-07-22 2024-05-29 KRKA, D.D., Novo Mesto Bilayer tablet comprising telmisartan and indapamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9210098B (en) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoles, drugs with this compounds, and process for their preparation
US5139114A (en) * 1991-03-18 1992-08-18 Abex Corporation Visible brake block wear indicator

Also Published As

Publication number Publication date
SA99200838B1 (en) 2006-03-06
HUP0105148A2 (en) 2002-07-29
ZA200104771B (en) 2002-12-02
HUP0105148A3 (en) 2003-01-28
HU227401B1 (en) 2011-05-30
AR035475A1 (en) 2004-06-02
EP1144386B1 (en) 2003-10-22
IL143634A0 (en) 2002-04-21
HRP20010514B1 (en) 2010-01-31
HRP20010514A2 (en) 2002-08-31
ES2208265T3 (en) 2004-06-16
CZ297412B6 (en) 2006-12-13
NZ513528A (en) 2003-08-29
EA200100730A1 (en) 2002-02-28
EE04344B1 (en) 2004-08-16
BG65027B1 (en) 2006-12-29
DE19901921A1 (en) 2000-08-03
SK285429B6 (en) 2007-01-04
NO319823B1 (en) 2005-09-19
DE19901921C2 (en) 2001-01-04
KR100658959B1 (en) 2006-12-19
JP2002535315A (en) 2002-10-22
CA2352436A1 (en) 2000-07-27
DK1144386T3 (en) 2004-01-12
PL349425A1 (en) 2002-07-29
YU51101A (en) 2004-05-12
IL143634A (en) 2006-10-05
EP1144386A1 (en) 2001-10-17
AU765081B2 (en) 2003-09-11
CN1144790C (en) 2004-04-07
BG105654A (en) 2002-01-31
MY122755A (en) 2006-05-31
WO2000043370A1 (en) 2000-07-27
PE20001362A1 (en) 2000-12-15
HK1041485A1 (en) 2002-07-12
DE50004150D1 (en) 2003-11-27
CO5150238A1 (en) 2002-04-29
RS50044B (en) 2008-11-28
NO20013560D0 (en) 2001-07-18
PT1144386E (en) 2004-03-31
CA2352436C (en) 2010-03-23
CZ20012634A3 (en) 2001-10-17
JP4700813B2 (en) 2011-06-15
UY25980A1 (en) 2001-08-27
AU2288100A (en) 2000-08-07
EA003065B1 (en) 2002-12-26
TWI280241B (en) 2007-05-01
UA56358C2 (en) 2003-05-15
HK1041485B (en) 2004-10-08
SK10202001A3 (en) 2001-12-03
BR0007584A (en) 2001-11-06
EE200100375A (en) 2002-10-15
KR20010101552A (en) 2001-11-14
ATE252564T1 (en) 2003-11-15
PL211829B1 (en) 2012-06-29
CN1336920A (en) 2002-02-20
TR200102074T2 (en) 2001-12-21

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Legal Events

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MM1K Lapsed by not paying the annual fees