NO20013039D0 - Apparat og fremgangsmåte for fremstilling av krystallinske partikler - Google Patents

Apparat og fremgangsmåte for fremstilling av krystallinske partikler

Info

Publication number
NO20013039D0
NO20013039D0 NO20013039A NO20013039A NO20013039D0 NO 20013039 D0 NO20013039 D0 NO 20013039D0 NO 20013039 A NO20013039 A NO 20013039A NO 20013039 A NO20013039 A NO 20013039A NO 20013039 D0 NO20013039 D0 NO 20013039D0
Authority
NO
Norway
Prior art keywords
preparation
crystalline particles
crystalline
particles
Prior art date
Application number
NO20013039A
Other languages
English (en)
Other versions
NO20013039L (no
Inventor
Robert William Lancaster
Hardev Singh
Andrew Lewis Theophilus
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20013039D0 publication Critical patent/NO20013039D0/no
Publication of NO20013039L publication Critical patent/NO20013039L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0059—General arrangements of crystallisation plant, e.g. flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/411—Emulsifying using electrical or magnetic fields, heat or vibrations
    • B01F23/4111—Emulsifying using electrical or magnetic fields, heat or vibrations using vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/85—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with a vibrating element inside the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/452—Magnetic mixers; Mixers with magnetically driven stirrers using independent floating stirring elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
    • B01J19/10—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor employing sonic or ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nozzles (AREA)
NO20013039A 1998-12-24 2001-06-19 Apparat og fremgangsmate for fremstilling av krystallinske partikler NO20013039L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9828721.2A GB9828721D0 (en) 1998-12-24 1998-12-24 Novel apparatus and process
PCT/GB1999/004368 WO2000038811A1 (en) 1998-12-24 1999-12-22 Apparatus and process for preparing crystalline particles

Publications (2)

Publication Number Publication Date
NO20013039D0 true NO20013039D0 (no) 2001-06-19
NO20013039L NO20013039L (no) 2001-08-22

Family

ID=10845091

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013039A NO20013039L (no) 1998-12-24 2001-06-19 Apparat og fremgangsmate for fremstilling av krystallinske partikler

Country Status (19)

Country Link
US (1) US6482438B1 (no)
EP (1) EP1144065A1 (no)
JP (1) JP3588050B2 (no)
KR (1) KR20010099933A (no)
CN (1) CN1335787A (no)
AU (1) AU759880B2 (no)
BR (1) BR9916587A (no)
CA (1) CA2356897A1 (no)
CZ (1) CZ20012331A3 (no)
GB (1) GB9828721D0 (no)
HK (1) HK1038709A1 (no)
HU (1) HUP0104855A3 (no)
IL (1) IL143811A (no)
NO (1) NO20013039L (no)
NZ (1) NZ512400A (no)
PL (1) PL349345A1 (no)
TR (1) TR200101845T2 (no)
WO (1) WO2000038811A1 (no)
ZA (1) ZA200105070B (no)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8123130B2 (en) 1998-04-17 2012-02-28 Remote Inc. Remote ordering device
US7090831B1 (en) 1999-04-14 2006-08-15 Smithkline Beecham Corporation Pharmaceutical aerosol formulation
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016002D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
AP1422A (en) 2000-08-05 2005-06-05 Glaxo Group Ltd 6.Alpha.,9.alpha.-difluoro-17.alpha.-'(2-furanylcarboxyl)oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent.
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
FI20002215A0 (fi) * 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
CN1302007C (zh) 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
DE60210622T2 (de) * 2001-05-05 2007-04-05 Accentus Plc Bildung kleiner Kristalle
DE10137017A1 (de) 2001-07-30 2003-02-20 Basf Ag Kristallisationsverfahren zur Einstellung kleiner Partikel
ATE336231T1 (de) * 2001-08-29 2006-09-15 Dow Global Technologies Inc Verfahren zur herstellung kristalliner arzneimittelteilchen durch ausfällung
GB0125604D0 (en) * 2001-10-25 2001-12-19 Glaxo Group Ltd Novel process
GB0201400D0 (en) 2002-01-22 2002-03-13 Glaxo Group Ltd Novel apparatus and process
KR20050006201A (ko) * 2002-04-29 2005-01-15 브리스톨-마이어스 스큅 컴퍼니 아토마이징을 이용하는 결정화 시스템
GB0219815D0 (en) * 2002-08-24 2002-10-02 Accentus Plc Preparation of small crystals
GB0212626D0 (en) * 2002-05-31 2002-07-10 Accentus Plc Production of crystalline ingredients
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0216700D0 (en) * 2002-07-18 2002-08-28 Astrazeneca Ab Process
CA2502502C (en) * 2002-10-17 2013-06-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for the manufacture of powders of inhalable medicaments
US20040197275A1 (en) 2002-10-17 2004-10-07 Ecole Polytechnique Federale De Lausanne Process for the manufacture of powders of inhalable medicaments
GB0302673D0 (en) 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
US7638138B2 (en) 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
SI1610878T1 (sl) * 2003-02-21 2015-02-27 University Of Bath Postopek za proizvodnjo delcev
CN100404545C (zh) * 2003-03-27 2008-07-23 尼科梅德有限责任公司 具有规定粒径的结晶环缩松的制备方法
AU2003220808B2 (en) 2003-03-27 2008-08-21 Bioactis Limited Powder medicine applicator for nasal cavity
MY143936A (en) * 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
SE0302029D0 (sv) * 2003-07-07 2003-07-07 Astrazeneca Ab Novel process
ITMI20032054A1 (it) 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
JP2005177746A (ja) * 2003-11-28 2005-07-07 Mitsubishi Chemicals Corp 有機化合物微粒子の製造方法
WO2005051511A1 (ja) * 2003-11-28 2005-06-09 Mitsubishi Chemical Corporation 有機化合物微粒子の製造方法
US8673360B2 (en) 2004-08-10 2014-03-18 Shin Nippon Biomedical Laboratories, Ltd. Compositions that enable rapid-acting and highly absorptive intranasal administration
EP1949891A1 (en) * 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
ATE404186T1 (de) * 2004-10-12 2008-08-15 Generics Uk Ltd Verfahren zur herstellung von suspensionsaerosolformulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden
US7314516B2 (en) * 2004-12-29 2008-01-01 Five Star Technologies, Inc. Hydrodynamic cavitation crystallization device and process
NZ556709A (en) 2005-02-10 2009-09-25 Glaxo Group Ltd Process for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
WO2006096906A1 (en) * 2005-03-18 2006-09-21 Nanomaterials Technology Pte Ltd Inhalable drug
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
EP1868577A4 (en) 2005-04-15 2009-12-09 Reddys Lab Inc Dr Lacidipine PARTICLE
DE102005053862A1 (de) * 2005-11-04 2007-05-10 Pharmasol Gmbh Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel
FR2897267A1 (fr) * 2006-02-16 2007-08-17 Flamel Technologies Sa Formes pharmaceutiques multimicroparticulaires pour administration per os
GB0610090D0 (en) * 2006-05-20 2006-06-28 Price Robert Particulate drug compositions and their uses
AU2013202835B2 (en) * 2006-06-14 2015-11-12 Generics [Uk] Limited Process for the preparation of S-fluoromethyl-6,9-difluoro-11-hydroxy-16-methyl-17-propionyloxy-3-oxo-androsta-1, 4-diene-17-carbothioate and intermediates
US7811381B2 (en) * 2006-06-14 2010-10-12 Sirkar Kamalesh K Antisolvent crystallization in porous hollow fiber devices and methods of use thereof
PT2044099E (pt) * 2006-06-14 2012-06-06 Generics Uk Ltd Processo de preparação s-fluorometil-6,9-difluoro-11- hidroxi-16-metil-17-propioniloxi-3-oxo-androsta-l,4- dieno-17-carbotioato e seus intermediários
EP2116264B1 (en) 2006-12-26 2017-09-27 Shin Nippon Biomedical Laboratories, Ltd. Preparation for transnasal application
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) * 2007-06-18 2007-07-25 Prosonix Ltd Process
JP2010111592A (ja) * 2008-11-04 2010-05-20 Aska Pharmaceutical Co Ltd プロピオン酸フルチカゾンを含む局所投与剤
GB0900080D0 (en) * 2009-01-06 2009-02-11 Prosonix Ltd An apparatus and process for producing crystals
DE102009008478A1 (de) * 2009-02-11 2010-08-19 PHAST Gesellschaft für pharmazeutische Qualitätsstandards mbH Vorrichtung und Verfahren zur Herstellung pharmazeutisch hochfeiner Partikel sowie zur Beschichtung solcher Partikel in Mikroreaktoren
WO2010131486A1 (en) 2009-05-15 2010-11-18 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
BR112012011336A2 (pt) 2009-10-22 2018-10-16 Api Genesis Llc Composições compreendendo flavonoides, seu método de preparação, adesivo para aplicação de flavonoide, métodos de produção de flavonoide hidratado,métodos de preparação de formulação tópica, e uso de flavonoide
AU2011232103B2 (en) 2010-03-22 2013-10-24 Instillo Gmbh Method and device for producing microparticles or nanoparticles
CN101862633B (zh) * 2010-07-10 2012-07-11 浙江卫信生物药业有限公司 全自动无菌恒温连续流体制剂超声波匀化处理装置
MX340839B (es) 2010-12-30 2016-07-27 Yava Tech Inc Particulas de compuestos de metal de transicion y metodos de produccion.
EP2500072A1 (en) 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
JP2014520848A (ja) * 2011-07-08 2014-08-25 ファイザー・リミテッド １型プロピオン酸フルチカゾンの調製のための方法
CA2872845C (en) * 2012-05-08 2021-11-09 Aciex Therapeutics, Inc. Preparation of nanocrystals of fluticasone propionate
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
DE102012221219B4 (de) * 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9452930B2 (en) * 2013-11-04 2016-09-27 New Jersey Institute Of Technology System and method for continuous polymer coating of particles
CN103977593B (zh) * 2014-05-19 2017-01-04 中国工程物理研究院化工材料研究所 制备纳米共晶含能材料的方法及装置
CN105012237B (zh) * 2015-08-10 2018-09-11 重庆华邦制药有限公司 糠酸氟替卡松鼻喷雾剂及其制备方法
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN109012260B (zh) * 2018-09-06 2020-10-02 董旭 一种便于配比的***物混合器
US20210369667A1 (en) 2019-03-29 2021-12-02 Vizuri Health Sciences Consumer Healthcare, Inc. Compositions and methods for the prevention and treatment of radiation dermatitis, eczema, burns, wounds and certain cancers

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL67349C (no) * 1946-01-16
DE1262240B (de) 1964-11-14 1968-03-07 Helmut Pelzer Dipl Chem Dr Verfahren zur Herstellung feinster Teilchen kristallisierbarer Verbindungen
DE2504347C3 (de) * 1975-02-03 1978-10-05 Dso, Pharmachim, Sofia Verfahren zur Herstellung von reinem Tetracyclinhydrochlorid
US3979269A (en) 1975-02-25 1976-09-07 DSO "Pharmachim Method for obtaining tetracyclinehydrochloride
WO1990003782A2 (en) * 1988-10-05 1990-04-19 The Upjohn Company Finely divided solid crystalline powders via precipitation into an anti-solvent
JPH02164712A (ja) 1988-12-17 1990-06-25 Tosoh Corp 重炭酸ナトリウムの製造方法
GB9005275D0 (en) 1990-03-09 1990-05-02 Atomic Energy Authority Uk Crystallization monitor
JPH0497908A (ja) 1990-08-10 1992-03-30 Lion Corp ゼオライトの製造方法
AU5171293A (en) 1992-10-14 1994-05-09 Regents Of The University Of Colorado, The Ion-pairing of drugs for improved efficacy and delivery
GB9307225D0 (en) 1993-04-03 1993-05-26 Atomic Energy Authority Uk Processing vessel
US5471001A (en) * 1994-12-15 1995-11-28 E. I. Du Pont De Nemours And Company Crystallization of adipic acid
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
US5905003A (en) 1995-06-26 1999-05-18 Energy Conversion Devices, Inc. Beta to gamma phase cycleable electrochemically active nickel hydroxide material
GB9624615D0 (en) 1996-11-26 1997-01-15 Zeneca Ltd Chrystallisation process
DE69841972D1 (de) * 1997-02-05 2010-12-09 Merck Sharp & Dohme Verfahren zur kristallisation eines reverstranskriptase-inhibitors, bei welchem ein anti-lösungsmittel benutzt wird
GB9826175D0 (en) 1998-11-28 1999-01-20 Smithkline Beecham Plc Novel process
GB9826242D0 (en) 1998-11-30 1999-01-20 Smithkline Beecham Plc Novel process
ES2251965T3 (es) 1999-01-29 2006-05-16 Bristol-Myers Squibb Company Aparato y procedimiento de cristalizacion por ultrasonidos con chorros en colision.

Also Published As

Publication number Publication date
NO20013039L (no) 2001-08-22
EP1144065A1 (en) 2001-10-17
GB9828721D0 (en) 1999-02-17
KR20010099933A (ko) 2001-11-09
CA2356897A1 (en) 2000-07-06
AU759880B2 (en) 2003-05-01
NZ512400A (en) 2003-02-28
JP2002533205A (ja) 2002-10-08
IL143811A0 (en) 2002-04-21
BR9916587A (pt) 2001-09-25
JP3588050B2 (ja) 2004-11-10
CZ20012331A3 (cs) 2002-03-13
AU1877100A (en) 2000-07-31
ZA200105070B (en) 2002-09-20
CN1335787A (zh) 2002-02-13
WO2000038811A1 (en) 2000-07-06
HUP0104855A3 (en) 2005-12-28
PL349345A1 (en) 2002-07-15
US6482438B1 (en) 2002-11-19
HUP0104855A2 (hu) 2002-04-29
IL143811A (en) 2005-06-19
TR200101845T2 (tr) 2001-10-22
HK1038709A1 (zh) 2002-03-28

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