NO20005508D0 - Adenosin-A3-reseptormodulatorer - Google Patents

Adenosin-A3-reseptormodulatorer

Info

Publication number
NO20005508D0
NO20005508D0 NO20005508A NO20005508A NO20005508D0 NO 20005508 D0 NO20005508 D0 NO 20005508D0 NO 20005508 A NO20005508 A NO 20005508A NO 20005508 A NO20005508 A NO 20005508A NO 20005508 D0 NO20005508 D0 NO 20005508D0
Authority
NO
Norway
Prior art keywords
adenosine
receptor modulators
modulators
receptor
Prior art date
Application number
NO20005508A
Other languages
English (en)
Other versions
NO20005508L (no
NO318078B1 (no
Inventor
Pier Giovanni Baraldi
Pier Andrea Borea
Original Assignee
Medco Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medco Res Inc filed Critical Medco Res Inc
Publication of NO20005508D0 publication Critical patent/NO20005508D0/no
Publication of NO20005508L publication Critical patent/NO20005508L/no
Publication of NO318078B1 publication Critical patent/NO318078B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/001Preparation for luminescence or biological staining
    • A61K49/0013Luminescence
    • A61K49/0017Fluorescence in vivo
    • A61K49/0019Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO20005508A 1998-09-16 2000-11-01 Adenosin-A3-reseptormodulatorer,deres anvendelse for fremstilling av preparater for a bestemme naervaer av tumorceller med hoy konsentrasjon av adenosin-A3-reseptor NO318078B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/154,435 US6448253B1 (en) 1998-09-16 1998-09-16 Adenosine A3 receptor modulators
US09/379,300 US6407236B1 (en) 1998-09-16 1999-08-23 Adenosine A3 receptor modulators
PCT/US1999/021103 WO2000015231A1 (en) 1998-09-16 1999-09-15 Adenosine a3 receptor modulators

Publications (3)

Publication Number Publication Date
NO20005508D0 true NO20005508D0 (no) 2000-11-01
NO20005508L NO20005508L (no) 2001-03-15
NO318078B1 NO318078B1 (no) 2005-01-31

Family

ID=22551355

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005508A NO318078B1 (no) 1998-09-16 2000-11-01 Adenosin-A3-reseptormodulatorer,deres anvendelse for fremstilling av preparater for a bestemme naervaer av tumorceller med hoy konsentrasjon av adenosin-A3-reseptor

Country Status (28)

Country Link
US (2) US6448253B1 (no)
JP (1) JP2002524519A (no)
KR (1) KR100448555B1 (no)
CN (1) CN1154494C (no)
AT (2) AT414240B (no)
AU (1) AU749211B2 (no)
BR (1) BR9913766A (no)
CA (1) CA2332007C (no)
CH (1) CH692132A5 (no)
DE (1) DE19983530T1 (no)
DK (1) DK200100432A (no)
ES (1) ES2204262B1 (no)
FI (1) FI116624B (no)
GB (1) GB2353527B (no)
HK (1) HK1035671A1 (no)
HU (1) HUP0102589A3 (no)
ID (1) ID28100A (no)
IL (1) IL156851A (no)
LU (1) LU90687B1 (no)
NO (1) NO318078B1 (no)
NZ (1) NZ509149A (no)
RO (1) RO121030B1 (no)
RU (1) RU2250904C2 (no)
SE (1) SE522578C2 (no)
TR (1) TR200003461T2 (no)
WO (1) WO2000015231A1 (no)
YU (1) YU83600A (no)
ZA (1) ZA200101626B (no)

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JP4284182B2 (ja) * 2001-11-30 2009-06-24 シェーリング コーポレイション アデノシンA2aレセプターアンタゴニスト
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US9227979B2 (en) * 2012-01-25 2016-01-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Fluorescent antagonists of the A3 adenosine receptor
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Also Published As

Publication number Publication date
ES2204262B1 (es) 2005-03-01
ATA904399A (de) 2006-01-15
HUP0102589A3 (en) 2002-01-28
NZ509149A (en) 2003-08-29
FI116624B (fi) 2006-01-13
SE0003984L (sv) 2000-12-22
LU90687B1 (en) 2000-12-19
KR20010089154A (ko) 2001-09-29
AU6248299A (en) 2000-04-03
AT503591A2 (de) 2007-11-15
HK1035671A1 (en) 2001-12-07
IL156851A (en) 2006-08-20
RU2250904C2 (ru) 2005-04-27
GB2353527B (en) 2004-02-25
NO20005508L (no) 2001-03-15
CN1303289A (zh) 2001-07-11
CA2332007A1 (en) 2000-03-23
ES2204262A1 (es) 2004-04-16
GB2353527A (en) 2001-02-28
DE19983530T1 (de) 2001-11-08
CN1154494C (zh) 2004-06-23
GB0027879D0 (en) 2000-12-27
WO2000015231A1 (en) 2000-03-23
WO2000015231A9 (en) 2000-08-17
ZA200101626B (en) 2001-12-13
AU749211B2 (en) 2002-06-20
TR200003461T2 (tr) 2001-06-21
JP2002524519A (ja) 2002-08-06
KR100448555B1 (ko) 2004-09-13
RO121030B1 (ro) 2006-11-30
US6407236B1 (en) 2002-06-18
HUP0102589A2 (hu) 2001-11-28
ID28100A (id) 2001-05-03
NO318078B1 (no) 2005-01-31
CA2332007C (en) 2007-08-07
SE522578C2 (sv) 2004-02-17
DK200100432A (da) 2001-03-14
FI20002367A (fi) 2001-01-19
WO2000015231A8 (en) 2000-06-15
CH692132A5 (de) 2002-02-28
US6448253B1 (en) 2002-09-10
SE0003984D0 (sv) 2000-11-01
YU83600A (sh) 2003-12-31
AT414240B (de) 2006-10-15
BR9913766A (pt) 2001-06-05

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