NO1999017I1 - Repaglinid - Google Patents

Repaglinid

Info

Publication number
NO1999017I1
NO1999017I1 NO1999017C NO1999017C NO1999017I1 NO 1999017 I1 NO1999017 I1 NO 1999017I1 NO 1999017 C NO1999017 C NO 1999017C NO 1999017 C NO1999017 C NO 1999017C NO 1999017 I1 NO1999017 I1 NO 1999017I1
Authority
NO
Norway
Prior art keywords
repaglinide
Prior art date
Application number
NO1999017C
Other languages
English (en)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36781542&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO1999017(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CA002111851A external-priority patent/CA2111851C/en
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO1999017I1 publication Critical patent/NO1999017I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO1999017C 1991-06-21 1999-07-20 Repaglinid NO1999017I1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP1991/001147 WO1993000337A1 (de) 1991-06-21 1991-06-21 (s)(+)-2-äthoxy-4-[n-[1-(2-piperidino-phenyl)-3-methyl-1-butyl]aminocarbonylmethyl]-benzoesäure
SG1996002715A SG43036A1 (en) 1991-06-21 1991-06-21 (S) (+) -2-ethoxy-4-[N-[1-(2-piperidino-phenyl)-3-methyl- 1-buthyl]aminocarbony methyl] - benzoic a cid
CA002111851A CA2111851C (en) 1991-06-21 1991-06-21 (s)(+)-2-ethoxy-4-[n-{1-(2-piperidino-phenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid
CN91104984A CN1048722C (zh) 1991-06-21 1991-07-22 (s)(+)-2-乙氧基-4-[n-[1-(2-哌啶子基-苯基)-3-甲基-1-丁基]氨基羰基甲基]苯甲酸,含该化合物的药物组合物及其制备方法

Publications (1)

Publication Number Publication Date
NO1999017I1 true NO1999017I1 (no) 1999-07-20

Family

ID=36781542

Family Applications (2)

Application Number Title Priority Date Filing Date
NO934726A NO303687B1 (no) 1991-06-21 1993-12-20 Analogifremgangsmåte for fremstilling av den terapeutisk aktive forbindelse (S)(+)-2-etoksy-4-[N-[1-(2-piperidino-fenyl)-3-metyl-1-butyl]aminokarbonylmetyl]-benzosyre
NO1999017C NO1999017I1 (no) 1991-06-21 1999-07-20 Repaglinid

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO934726A NO303687B1 (no) 1991-06-21 1993-12-20 Analogifremgangsmåte for fremstilling av den terapeutisk aktive forbindelse (S)(+)-2-etoksy-4-[N-[1-(2-piperidino-fenyl)-3-metyl-1-butyl]aminokarbonylmetyl]-benzosyre

Country Status (8)

Country Link
EP (1) EP0589874B1 (no)
JP (1) JP2921982B2 (no)
CN (1) CN1048722C (no)
AU (1) AU660930B2 (no)
FI (1) FI106027B (no)
NO (2) NO303687B1 (no)
SG (1) SG43036A1 (no)
WO (1) WO1993000337A1 (no)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE201139T1 (de) 1997-06-13 2001-06-15 Novo Nordisk As Neue dosierung für diabetes type 2
IN192862B (no) * 1999-11-16 2004-05-22 Ranbaxy Lab Ltd
AR033390A1 (es) 2000-08-22 2003-12-17 Novartis Ag Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
US20040102477A1 (en) * 2002-08-23 2004-05-27 Dr. Reddy's Laboratories Limited Polymorphic forms of (S)-Repaglinide and the processes for preparation thereof
US7915421B2 (en) 2003-05-14 2011-03-29 Cilag Ltd. Method for preparing phenyl acetic acid derivatives
AU2003237595A1 (en) * 2003-05-26 2004-12-13 Biocon Limited Process for the preparation of s(+)-2-ethoxy-4-(n-{1-(2-piperidinophelyl)-3-methyl-1- butyl} aminocarbonylmethyl)benzoic acid derivatives
WO2005021524A1 (en) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Process for the preparation of amorphous form of repaglinide
CN1305863C (zh) * 2004-12-27 2007-03-21 浙江大学 (s)－异丙基－(2－哌啶)苯基－甲基胺的合成方法
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
FR2898894B1 (fr) * 2006-03-24 2008-06-06 Genfit Sa Composes derives de n-(phenethyl)benzamide substitues, preparation et utilisations
US7763607B2 (en) * 2006-04-27 2010-07-27 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators
BRPI0718420A2 (pt) * 2006-10-20 2013-11-12 Cpd Llc Método de restabelecimento do efeito da incretina
US8101769B2 (en) 2007-02-15 2012-01-24 Actavis Group Ptc Ehf Process for preparing ethyl (S)-2-ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of Repaglinide
US20100197732A1 (en) * 2007-06-06 2010-08-05 Actavis Group Ptc Ehf Repaglinide Substantially Free of Dimer Impurity
EP2019097A1 (en) 2007-07-25 2009-01-28 Aurobindo Pharma Limited Process for preparing (alphaS)-alpha-(2-methylpropyl)-2-(1-piperidinyl)benzenemethanamine
DE102008046995B4 (de) * 2008-09-12 2010-08-26 Stada Arzneimittel Ag 2-Ethoxy-benzoesäurederivat
EP2177221A1 (en) 2008-10-20 2010-04-21 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of substantially optically pure Repaglinide and precursors thereof
JP5654572B2 (ja) 2009-05-15 2015-01-14 ノバルティス アーゲー アルドステロンシンターゼ阻害剤としてのベンズオキサゾロン誘導体
MA33358B1 (fr) 2009-05-15 2012-06-01 Novartis Ag Arylpyridine en tant qu'inhibiteurs de l'aldostérone synthase
ES2602826T3 (es) 2009-05-28 2017-02-22 Novartis Ag Derivados aminobutíricos sustituidos como inhibidores de neprilisina
MA33364B1 (fr) 2009-05-28 2012-06-01 Novartis Ag Dérivés aminobutyriques substitués en tant qu'inhibiteurs de néprilysine
US8519134B2 (en) 2009-11-17 2013-08-27 Novartis Ag Aryl-pyridine derivatives as aldosterone synthase inhibitors
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
EP2507234B1 (en) 2009-11-30 2014-03-12 Novartis AG Imidazole derivatives as aldosterone synthase inhibitors
EP2364977A1 (en) 2010-01-26 2011-09-14 Reuter Chemische Apparatebau KG Process for the enantiomeric enrichment of 3-methyl-1-(2-piperidinophenyl)-1-butylamine
US8877815B2 (en) 2010-11-16 2014-11-04 Novartis Ag Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
US8673974B2 (en) 2010-11-16 2014-03-18 Novartis Ag Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
CN102267959B (zh) * 2011-07-06 2013-05-01 海南锦瑞制药股份有限公司 一种瑞格列奈晶体、其制备方法及含有该晶体的固体口服制剂
CN103012319B (zh) * 2011-09-20 2015-06-10 浙江九洲药业股份有限公司 瑞格列奈中间体的合成工艺改进
CN102584743A (zh) * 2011-12-28 2012-07-18 中国药科大学 对二甲氨基吡啶瑞格列奈共晶
UY35144A (es) 2012-11-20 2014-06-30 Novartis Ag Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
AP2015008621A0 (en) 2013-02-14 2015-07-31 Novartis Ag Substituted bisphenyl butanoic nep 'neutral endopeptidase' inhibitors
UY35670A (es) 2013-07-25 2015-02-27 Novartis Ag Polipéptidos cíclicos para el tratamiento de insuficiencia cardíaca
JP2016527249A (ja) 2013-07-25 2016-09-08 ノバルティス アーゲー 合成アペリンポリペプチドのバイオコンジュゲート
ES2787223T3 (es) 2014-11-07 2020-10-15 Univ Minnesota Sales y composiciones útiles para tratar enfermedades
KR20170103970A (ko) 2015-01-23 2017-09-13 노파르티스 아게 개선된 반감기를 갖는 합성 아펠린 지방산 접합체
WO2018034627A1 (en) 2016-08-18 2018-02-22 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Pharmaceutical composition of antidiabetic tablet
UY38072A (es) 2018-02-07 2019-10-01 Novartis Ag Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3347565A1 (de) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI935724A (fi) 1993-12-20
CN1048722C (zh) 2000-01-26
JPH06508816A (ja) 1994-10-06
NO934726D0 (no) 1993-12-20
SG43036A1 (en) 1997-10-17
FI106027B (fi) 2000-11-15
NO303687B1 (no) 1998-08-17
NO934726L (no) 1993-12-20
WO1993000337A1 (de) 1993-01-07
AU8078191A (en) 1993-01-25
EP0589874A1 (de) 1994-04-06
EP0589874B1 (de) 1999-09-08
AU660930B2 (en) 1995-07-13
FI935724A0 (fi) 1993-12-20
CN1068820A (zh) 1993-02-10
JP2921982B2 (ja) 1999-07-19

Similar Documents

Publication Publication Date Title
NO1999017I1 (no) Repaglinid
FI925387A0 (fi) Soekarrangemang i centralsystem foer cellulaer mobiltelefoni
FI930855A0 (fi) Tillaempningarnas modularitet i datakommunikationscentraler
FI933855A0 (fi) Kontinuerlig blandningsmaskin uppdelad i sektioner
FI932245A (fi) Faskombinationsfoerfarande och -anordning foer anvaendning i en flerantennmottagare
FI924733A (fi) Envaegsspruta
FI922965A (fi) Atomiseringsdysa
FI913599A (fi) Traodloes koppling foer en telemetrisk mottagare
FI933697A0 (fi) 3-piperidinylmetylkarboxylatsubstituerade indoler
FI921435A (fi) Skydd foer saenkpump i svaora foerhaollanden
FI922759A (fi) Loesningsmedelskompositioner foer anvaendning i tryckkaensligt kopieringspapper
FI923724A (fi) Monterings- och distansanordning foer braenslestavarna i en kokvattenreaktor
FI925206A (fi) Rengoerningsprodukt i vaetskeform
FI935507A (fi) Foerbaettring i en lyftbommekanism
FI935566A (fi) Insertionsmutationer i mycobakterier
FI924750A (fi) Zirkoniumbaserad legering foer komponenter i kaernreaktorer
FI922180A (fi) Tuggummi innehaollande tuggummibas i en valsningsblandning
FI924842A (fi) Laogfetthaltig vispbar icke-mejeri-graedde
FI922362A (fi) Bromstrumma
FI920998A (fi) Skaermad hytt i modulkonstruktion
FI932142A (fi) Stenborrkrona
FI925827A (fi) Tvaerbindbar polymerisk komposition
FI924078A (fi) Borrnings- och borrstaongsanordning
FI912432A (fi) Matningsanordning
FI922779A (fi) Bestrykningsbett