NO175871B - - Google Patents

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Publication number: NO175871B
Authority: NO; Norway
Prior art keywords: yeast; dna; fragment; promoter; gene
Prior art date: 1985-08-29

Application number

NO863458A

Other languages

English (en)

Norwegian (no)

Other versions

NO863458L (no

NO175871C (no

NO863458D0 (no

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-29

Filing date

1986-08-28

Publication date

1994-09-12

1986-08-28 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1986-08-28 Publication of NO863458D0 publication Critical patent/NO863458D0/no

1987-03-02 Publication of NO863458L publication Critical patent/NO863458L/no

1994-09-12 Publication of NO175871B publication Critical patent/NO175871B/no

1994-12-21 Publication of NO175871C publication Critical patent/NO175871C/no

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Mycology (AREA)
Toxicology (AREA)
Diabetes (AREA)
Tropical Medicine & Parasitology (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Plant Pathology (AREA)
Endocrinology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Alcoholic Beverages (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Graft Or Block Polymers (AREA)
Led Devices (AREA)
Gyroscopes (AREA)
Enzymes And Modification Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)

NO863458A 1985-08-29 1986-08-28 Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær NO175871C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB858521496A GB8521496D0 (en)	1985-08-29	1985-08-29	Repressible yeast promoters

Publications (4)

Publication Number	Publication Date
NO863458D0 NO863458D0 (no)	1986-08-28
NO863458L NO863458L (no)	1987-03-02
NO175871B true NO175871B (fr)	1994-09-12
NO175871C NO175871C (no)	1994-12-21

Family

ID=10584428

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO863458A NO175871C (no)	1985-08-29	1986-08-28	Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær

Country Status (22)

Country	Link
US (1)	US5436136A (fr)
EP (1)	EP0213593B1 (fr)
JP (1)	JPH07110233B2 (fr)
AT (1)	ATE62510T1 (fr)
AU (1)	AU599329B2 (fr)
CA (1)	CA1318616C (fr)
DD (2)	DD254212A5 (fr)
DE (1)	DE3678647D1 (fr)
DK (1)	DK175093B1 (fr)
ES (3)	ES2001618A6 (fr)
FI (1)	FI91280C (fr)
GB (1)	GB8521496D0 (fr)
GR (1)	GR862209B (fr)
HU (1)	HU211207B (fr)
IE (1)	IE58844B1 (fr)
IL (1)	IL79837A (fr)
NO (1)	NO175871C (fr)
NZ (1)	NZ217388A (fr)
PH (1)	PH24715A (fr)
PT (1)	PT83273B (fr)
SU (1)	SU1630616A3 (fr)
ZA (1)	ZA866535B (fr)

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EP0245479B1 (fr) *	1985-11-13	1993-02-17	Xoma Corporation	Promoteur de kinase de phosphoglycerate raccourci
MY101203A (en) *	1985-12-12	1991-08-17	Ucp Gen Pharma Ag	Production of thrombin iinhibitors.
GB8530631D0 (en)	1985-12-12	1986-01-22	Ciba Geigy Ag	Thrombin inhibitors
GB8620926D0 (en) *	1986-08-29	1986-10-08	Delta Biotechnology Ltd	Yeast promoter
GB8907110D0 (en) *	1988-05-04	1989-05-10	Ciba Geigy Ag	Improvements in the production of polypeptides
NO177065C (no) *	1988-09-26	1995-07-12	Labofina Sa	Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
WO1992004363A1 (fr) *	1990-09-04	1992-03-19	The Salk Institute Biotechnology/Industrial Associates, Inc.	Production du facteur-1 de croissance similaire a l'insuline dans des cellules de levure methylotrophique
US5612198A (en) *	1990-09-04	1997-03-18	The Salk Institute	Production of insulin-like growth factor-1 in methylotrophic yeast cells
ATE220105T1 (de) *	1991-04-01	2002-07-15	Merck & Co Inc	Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
US5674728A (en) *	1993-11-03	1997-10-07	Novartis Corporation	Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) *	1994-05-25	1996-07-09	Kirin Brewery Co Ltd	キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
CA2266543C (fr) *	1996-09-24	2003-12-09	Cadus Pharmaceutical Corporation	Procedes et compositions pour identifier des modulateurs de recepteur
US6265186B1 (en)	1997-04-11	2001-07-24	Dsm N.V.	Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en)	1999-12-10	2005-05-10	The Salk Institute	Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) *	2001-01-25	2011-08-30	Evolva Sa	Concatemers of differentially expressed multiple genes
US9476082B2 (en)	2010-05-20	2016-10-25	Evolva Sa	Method of producing isoprenoid compounds in yeast
CN116018350A (zh)	2020-04-20	2023-04-25	韦斯塔隆公司	用于有害生物防治的蛋白水解稳定的U1-漏斗网蛛毒素-Ta1b变体多肽
JP2023524083A (ja)	2020-05-01	2023-06-08	ヴェスタロン・コーポレーション	殺虫剤の組み合わせ
CA3215602A1 (fr)	2021-04-01	2022-10-06	Vestaron Corporation	Polypeptides mutants av3 destines a la lutte antiparasitaire
WO2023122805A1 (fr)	2021-12-20	2023-06-29	Vestaron Corporation	Procédé de pression de sélection par sorbitol
WO2023225555A1 (fr)	2022-05-18	2023-11-23	Vestaron Corporation	Variants peptidiques d'actx pesticides
WO2023245100A1 (fr)	2022-06-17	2023-12-21	Vestaron Corporation	Peptides variants de ncr13 antimicrobiens
WO2024026406A2 (fr)	2022-07-29	2024-02-01	Vestaron Corporation	Peptides actx de nouvelle génération

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GB2125047B (en) *	1982-08-09	1986-02-19	Ciba Geigy Ag	Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) *	1982-08-13	1988-09-22	Zymogenetics Inc.	Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) *	1983-02-22	1989-10-24	Chiron Corporation	Eukaryotic regulatable transcription
NZ207926A (en) *	1983-04-25	1988-04-29	Genentech Inc	Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
ATE78293T1 (de) *	1983-05-27	1992-08-15	Texas A & M Univ Sys	Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
GB8314961D0 (en) *	1983-05-31	1983-07-06	Kingsman A J	Dna sequence
DD229151A5 (de) *	1983-11-21	1985-10-30	Ciba Geigy Ag	Verfahren zur herstellung von gewebeplasminogenaktivatoren
EP0164556B1 (fr) *	1984-05-11	1994-03-02	Chiron Corporation	Transcription augmentée dans les levures par usage d'une construction hybride de la région du promoteur
EP0164566A3 (fr) *	1984-05-11	1986-10-29	LGA Gastechnik GmbH	Dispositif de sécurité pour réservoirs de gaz liquéfié
US4895800A (en) *	1985-11-26	1990-01-23	Phillips Petroleum Company	Yeast production of hepatitis B surface antigen

1985
- 1985-08-29 GB GB858521496A patent/GB8521496D0/en active Pending
1986
- 1986-08-25 FI FI863430A patent/FI91280C/fi not_active IP Right Cessation
- 1986-08-25 IL IL79837A patent/IL79837A/xx not_active IP Right Cessation
- 1986-08-26 DE DE8686111820T patent/DE3678647D1/de not_active Expired - Lifetime
- 1986-08-26 AT AT86111820T patent/ATE62510T1/de not_active IP Right Cessation
- 1986-08-26 EP EP86111820A patent/EP0213593B1/fr not_active Expired - Lifetime
- 1986-08-27 GR GR862209A patent/GR862209B/el unknown
- 1986-08-27 DD DD29389486A patent/DD254212A5/de not_active IP Right Cessation
- 1986-08-27 DD DD31325586A patent/DD267739A5/de unknown
- 1986-08-27 CA CA000516879A patent/CA1318616C/fr not_active Expired - Lifetime
- 1986-08-28 ZA ZA866535A patent/ZA866535B/xx unknown
- 1986-08-28 IE IE230786A patent/IE58844B1/en not_active IP Right Cessation
- 1986-08-28 HU HU863720A patent/HU211207B/hu unknown
- 1986-08-28 NZ NZ217388A patent/NZ217388A/xx unknown
- 1986-08-28 DK DK198604096A patent/DK175093B1/da not_active IP Right Cessation
- 1986-08-28 PT PT83273A patent/PT83273B/pt unknown
- 1986-08-28 AU AU62032/86A patent/AU599329B2/en not_active Expired
- 1986-08-28 PH PH34192A patent/PH24715A/en unknown
- 1986-08-28 NO NO863458A patent/NO175871C/no not_active IP Right Cessation
- 1986-08-28 SU SU864028035A patent/SU1630616A3/ru active
- 1986-08-29 JP JP61201924A patent/JPH07110233B2/ja not_active Expired - Lifetime
- 1986-08-29 ES ES8601490A patent/ES2001618A6/es not_active Expired
1988
- 1988-03-16 ES ES8800794A patent/ES2006382A6/es not_active Expired
- 1988-03-16 ES ES8800795A patent/ES2006383A6/es not_active Expired
1991
- 1991-12-20 US US07/811,898 patent/US5436136A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SU1630616A3 (ru)	1991-02-23
AU599329B2 (en)	1990-07-19
IE862307L (en)	1987-02-28
JPS6251995A (ja)	1987-03-06
DE3678647D1 (en)	1991-05-16
ES2006382A6 (es)	1989-04-16
IL79837A (en)	1992-06-21
ZA866535B (en)	1987-04-29
US5436136A (en)	1995-07-25
FI863430A0 (fi)	1986-08-25
IL79837A0 (en)	1986-11-30
FI91280B (fi)	1994-02-28
PH24715A (en)	1990-10-01
DK409686D0 (da)	1986-08-28
DD267739A5 (de)	1989-05-10
NO863458L (no)	1987-03-02
CA1318616C (fr)	1993-06-01
EP0213593B1 (fr)	1991-04-10
FI863430A (fi)	1987-03-01
GR862209B (en)	1986-12-31
ATE62510T1 (de)	1991-04-15
ES2001618A6 (es)	1988-06-01
JPH07110233B2 (ja)	1995-11-29
DK175093B1 (da)	2004-05-24
NO175871C (no)	1994-12-21
PT83273B (pt)	1989-05-12
DD254212A5 (de)	1988-02-17
DK409686A (da)	1987-03-01
IE58844B1 (en)	1993-11-17
NZ217388A (en)	1989-02-24
FI91280C (fi)	1994-06-10
NO863458D0 (no)	1986-08-28
AU6203286A (en)	1987-03-05
GB8521496D0 (en)	1985-10-02
HU211207B (en)	1995-11-28
PT83273A (en)	1986-09-01
ES2006383A6 (es)	1989-04-16
HUT42525A (en)	1987-07-28
EP0213593A1 (fr)	1987-03-11

Legal Events

Date	Code	Title	Description
2006-10-09	MK1K	Patent expired

Publication	Publication Date	Title
NO175871B (fr)	1994-09-12
EP0100561B1 (fr)	1989-05-31	Vecteurs hybrides de levure et leur utilisation pour la production des polypeptides
US5102789A (en)	1992-04-07	Production of epideramal growth factor in pichia pastoris yeast cells
EP0123544A2 (fr)	1984-10-31	Procédé d'expression de protéines hétérologues dans les levures, vecteurs d'expression et micro-organismes du genre levure à cet effet
EP0088632B1 (fr)	1993-06-16	Expression, traitement et excrétion de protéine hétérologue par des levures
Chang et al.	1986	Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides
CZ284251B6 (cs)	1998-10-14	Způsob výroby heterologního proteinu v transformované buňce
JPH07503368A (ja)	1995-04-13	新規な生物活性ポリペプチド類，ならびにそれらの製造および含有薬学組成物
FI94773B (fi)	1995-07-14	Menetelmä trombiini-inhibiittorien tuottamiseksi
JPS6236183A (ja)	1987-02-17	サツカロミセス・セレビシエからのポリペプチドの発現および分泌
CN113423836A (zh)	2021-09-21	重组宿主细胞中碳源调节的蛋白的产生
US5939287A (en)	1999-08-17	Method for production of proteins in yeast
US7198919B1 (en)	2007-04-03	Use of alpha factor sequences in yeast expression systems
NO179046B (no)	1996-04-15	Fremgangsmåte for fremstilling av biologisk aktivt human enkelt kjede urokinase-type plasminogenaktivator
EP0264118B1 (fr)	1993-08-04	Méthode de préparation de protéines
Goodey et al.	1987	Expression and secretion of foreign polypeptides in yeast
KR940011534B1 (ko)	1994-12-20	억제성 효모 프로모터의 제조방법
PH26266A (en)	1992-04-01	Yeast hybrid vectors and their use for the production of polypeptides