NO167511B - ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED TIENO (3,4-D) IMIDAZOLD DERIVATIVES. - Google Patents
ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED TIENO (3,4-D) IMIDAZOLD DERIVATIVES. Download PDFInfo
- Publication number
- NO167511B NO167511B NO883610A NO883610A NO167511B NO 167511 B NO167511 B NO 167511B NO 883610 A NO883610 A NO 883610A NO 883610 A NO883610 A NO 883610A NO 167511 B NO167511 B NO 167511B
- Authority
- NO
- Norway
- Prior art keywords
- partition
- wall
- housing
- valve
- partition wall
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000005192 partition Methods 0.000 claims description 29
- 230000002093 peripheral effect Effects 0.000 claims description 9
- 239000012528 membrane Substances 0.000 claims description 8
- 239000013013 elastic material Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Description
Avsteng n i ngsventi I. Shut off n i ngventi I.
Oppfinnelsen vedrører en avstengningsventil, hvor huset er utstyrt med et mellomstykke, som danner en skillevegg mellom husets innstrøm-nings- og utstrømningsside, og som ved sin omkrets går over i en omkretsvegg, som på begge sider av skilleveggen er utstyrt med gjennom-strømningsslisser og omsluttes av en hylseformet membran, som med begge ender er festet i huset, og hvor det på membranens utside er anordnet et kammer, hvor det kan tilføres et trykkmedium, som for eksempel kjent fra østerriksk pa-tentskrift nr. 184 012. The invention relates to a shut-off valve, where the housing is equipped with an intermediate piece, which forms a partition wall between the inflow and outflow side of the housing, and which at its circumference merges into a peripheral wall, which on both sides of the partition wall is equipped with flow-through slots and is enclosed by a sleeve-shaped membrane, which is attached to the housing at both ends, and where a chamber is arranged on the outside of the membrane, where a pressure medium can be supplied, as for example known from Austrian patent document no. 184 012.
Ved slike kjente avstengningsventiler danner mellomstykkets omkretsvegg, som forløper på begge sider av skilleveggen, ett stykke med skilleveggen. På innsiden av omkretsveggen fore-ligger aksiale ribber, og gjennomstrømningsslis-sene strekker seg helt frem til disse ribber. Ved denne anordning utformes slissene ved fjernelse av mellomstykkets materiale frem til ribbene, men anordningen har den ulempe at den krever forholdsvis komplisert bearbeidelse og at man ikke kan oppnå godt avrundete kanter på slissene, særlig på innsiden av mellomstykkets omkretsvegg. In the case of such known shut-off valves, the peripheral wall of the intermediate piece, which extends on both sides of the partition wall, forms one piece with the partition wall. On the inside of the peripheral wall, there are axial ribs, and the flow slots extend all the way to these ribs. With this device, the slots are formed by removing the intermediate piece's material up to the ribs, but the device has the disadvantage that it requires relatively complicated processing and that you cannot achieve well-rounded edges on the slots, especially on the inside of the intermediate piece's peripheral wall.
Oppfinnelsen har til hensikt å forbedre disse kjente avstengningsventiler. Ifølge oppfinnelsen består mellomstykkets omkretsvegg i det minste på den ene siden av skilleveggen av aksialt for-løpende staver, som med sine ender på den ene siden er ført inn i en ring av elastisk materiale anordnet på skilleveggens omkrets, og som med sine andre ender er avstøttet mot husets nærliggende kortvegg. Idet stavene overhodet ikke krever bearbeidelse, er mellomstykkenes frem-stilling meget enkel. Dessuten oppnåes den for-del at mellomstykkets passasje kan endres valg-fritt ved tilføyelse eller fjernelse av staver. Idet stavene kan ha rundt tverrsnitt, vil slissene mellom stavene ikke få skarpe kanter, slik at strøm-ningsforholdene ved slissene blir meget gunstige. Stavenes materiale kan være metall eller et kjemisk varig kunststoff. The invention aims to improve these known shut-off valves. According to the invention, the peripheral wall of the intermediate piece consists, at least on one side of the partition wall, of axially extending rods, which with their ends on one side are led into a ring of elastic material arranged on the perimeter of the partition wall, and which with their other ends are propped up against the nearby short wall of the house. As the rods do not require processing at all, the manufacture of the intermediate pieces is very simple. In addition, the advantage is achieved that the intermediate piece's passage can be changed as desired by adding or removing rods. Since the rods can have a round cross-section, the slots between the rods will not have sharp edges, so that the flow conditions at the slots will be very favorable. The rod's material can be metal or a chemically durable plastic.
Ved en hensiktsmessig utførelsesform av ventilen ifølge oppfinnelsen er skilleveggen hul og skilleveggens ene sideparti er forbundet med husets ene endestykke, mens skilleveggens annet sideparti er forbundet med husets andre endestykke og skilleveggens elastiske omkretsvegg er fastklemt mellom veggens sidepartier. In a suitable embodiment of the valve according to the invention, the partition wall is hollow and one side part of the partition wall is connected to one end piece of the housing, while the other side part of the partition wall is connected to the other end piece of the housing and the elastic peripheral wall of the partition wall is clamped between the side parts of the wall.
I tegningen er det vist et par utførelses-eksempler av avstengningsventilen ifølge oppfinnelsen. Fig. 1 viser et lengdesnitt av ventilen i lukket stilling. Fig. 2 er et tverrsnitt gjennom samme ventil etter linjen II—II i flg. 1. Fig. 3 og 4 viser hver sitt halve lengdesnitt gjennom en ventil i en modifisert utførelse. The drawing shows a couple of design examples of the shut-off valve according to the invention. Fig. 1 shows a longitudinal section of the valve in the closed position. Fig. 2 is a cross-section through the same valve following the line II—II in Fig. 1. Fig. 3 and 4 each show a half longitudinal section through a valve in a modified design.
Ventilens hus består av to endestykker 1 og et mer eller mindre sylindrisk mellomstykke 2 og disse deler er klemt sammen ved hjelp av klemskruer 3 som er fordelt over husets omkrets. I huset er det anordnet et mellomstykke, som danner en skillevegg mellom husets innstrømnings-og utstrømningsside og som på begge sider har en rund omkretsvegg. Skilleveggen består av to halvdeler 4, som ved den i fig. 1 og 2 viste anordning ved hjelp av ribber 5 er forbundet med hver sitt endestykke 1 av huset. The valve's housing consists of two end pieces 1 and a more or less cylindrical intermediate piece 2 and these parts are clamped together by means of clamping screws 3 which are distributed over the circumference of the housing. An intermediate piece is arranged in the house, which forms a dividing wall between the inflow and outflow side of the house and which has a round peripheral wall on both sides. The partition consists of two halves 4, as in the one in fig. The device shown in 1 and 2 is connected to each end piece 1 of the housing by means of ribs 5.
Skruene 3 tjener dessuten til å klemme fast membranen 7, som for dette formål er utstyrt med flenser 8. Gjennom en eller flere åpninger 9 tilføres et trykkmedium til membranens 7 utside, slik at membranen presses inn. The screws 3 also serve to clamp the membrane 7, which for this purpose is equipped with flanges 8. Through one or more openings 9, a pressure medium is supplied to the outside of the membrane 7, so that the membrane is pressed in.
Ved den utførelsesform som er vist i fig. 1 og 2, omsluttes den av halvdelene 4 dannede skillevegg av en elastisk ring 10, f. eks. av gummi, som med en innoverrettet kant 11 mellom vegghalvdelene 4 også klemmes fast av skruene 3. På begge sideflater av ringen 10 er staver 13 ført inn i utsparinger 12 i ringen og stavenes andre ender er likeledes avstøttet i utsparinger i rin-ger 14 av et elastisk materiale, f. eks. gummi. Ringene 14 er skjøvet på en skulder 15 av husets nærliggende endestykke 1. In the embodiment shown in fig. 1 and 2, the dividing wall formed by the halves 4 is enclosed by an elastic ring 10, e.g. of rubber, which with an inwardly directed edge 11 between the wall halves 4 is also clamped by the screws 3. On both side surfaces of the ring 10, rods 13 are guided into recesses 12 in the ring and the other ends of the rods are likewise supported in recesses in rings 14 of an elastic material, e.g. rubber. The rings 14 are pushed onto a shoulder 15 of the housing's nearby end piece 1.
Ved den utførelsesform som er vist i fig. 3, er stavene på skilleveggens utstrømningsside forbundet med tilsvarende halvdel 4 av skilleveggen. På skilleveggens innstrømningsside er enkelte av stavene 13 avstøttet i skilleveggens elastiske omkretsring 10 og de øvrige staver 13 er også her forbundet med skilleveggens tilsvarende halvdel 4, slik at stavene rager gjennom ringen 10. Mellom skilleveggens halvdeler 4 er det anordnet en tetningsring 16. In the embodiment shown in fig. 3, the rods on the outflow side of the partition are connected to the corresponding half 4 of the partition. On the inflow side of the partition, some of the rods 13 are supported in the elastic circumferential ring 10 of the partition and the other rods 13 are also here connected to the corresponding half 4 of the partition, so that the rods project through the ring 10. A sealing ring 16 is arranged between the halves 4 of the partition.
Ved den anordning som er vist i fig. 4, er skilleveggens halvdeler 4 forsynt med hver sin elastiske omkretsring 10, hvori i det minste enkelte av stavene 13 på begge sider av skilleveggen er avstøttet, mens de øvrige staver 13, som er forbundet med den tilhørende side av skilleveggen, rager gjennom ringen 10. In the device shown in fig. 4, the partition halves 4 are each provided with an elastic circumferential ring 10, in which at least some of the rods 13 on both sides of the partition are supported, while the other rods 13, which are connected to the corresponding side of the partition, project through the ring 10 .
Både ved utførelsesformen som vist i fig. 3 og den som er vist i fig. 4 er det anordnet gjen-nomgående klemskruer 3, som strekker seg langs utsiden av husets mellomstykke 2. Both in the embodiment as shown in fig. 3 and the one shown in fig. 4, clamping screws 3 are arranged throughout, which extend along the outside of the intermediate piece 2 of the housing.
I den stilling som er vist i tegningen, er den midtre del av membranen 7 i anlegg mot den elastiske ringens 10 ytre omkrets, og god tetning sikres således ved mellomstykkets omkrets, når ventilen er lukket. In the position shown in the drawing, the middle part of the membrane 7 is in contact with the outer circumference of the elastic ring 10, and a good seal is thus ensured at the circumference of the intermediate piece, when the valve is closed.
Claims (3)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3727244 | 1987-08-15 | ||
DE3744022 | 1987-12-24 | ||
DE3816996 | 1988-05-19 |
Publications (4)
Publication Number | Publication Date |
---|---|
NO883610D0 NO883610D0 (en) | 1988-08-12 |
NO883610L NO883610L (en) | 1989-02-16 |
NO167511B true NO167511B (en) | 1991-08-05 |
NO167511C NO167511C (en) | 1991-11-13 |
Family
ID=27196347
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO883610A NO167511C (en) | 1987-08-15 | 1988-08-12 | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED TIENO (3,4-D) IMIDAZOLD DERIVATIVES. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0304732A3 (en) |
JP (1) | JPS6470492A (en) |
KR (1) | KR890003772A (en) |
CN (1) | CN1029973C (en) |
CA (1) | CA1268461A (en) |
DE (1) | DE3827276A1 (en) |
DK (1) | DK454588A (en) |
FI (1) | FI89602C (en) |
HU (1) | HU208539B (en) |
IL (1) | IL87428A (en) |
MA (1) | MA21352A1 (en) |
NO (1) | NO167511C (en) |
NZ (1) | NZ225805A (en) |
PT (1) | PT88258B (en) |
TN (1) | TNSN88083A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI885878A (en) * | 1987-12-22 | 1989-06-23 | Hoechst Ag | SUBSTITUTE TIENOIMIDAZOLDERIVAT, FOERFARANDE FOER DERAS FRAMSTAELLNING, DESSA INNEHAOLLANDE PHARMACEUTICAL COMPOSITION OCH DERAS ANVAENDNING SOM INHIBITORER VID AVSOENDRING AV MAGSYRA. |
US5164407A (en) * | 1989-07-03 | 1992-11-17 | Merck & Co., Inc. | Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists |
CN108191745A (en) * | 2018-01-08 | 2018-06-22 | 滁州学院 | The preparation method of 2- methylol -3,4- dimethoxy-pyridines |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8417171D0 (en) * | 1984-07-05 | 1984-08-08 | Beecham Group Plc | Compounds |
FI861772A (en) * | 1985-05-07 | 1986-11-08 | Chemie Linz Ag | THEN THEN (2,3-D) IMIDED INSULATED FOR THE FRAME FRAMEWORK. |
ES2032394T3 (en) * | 1986-02-20 | 1993-02-16 | Hoechst Aktiengesellschaft | PROCEDURE FOR PREPARING SUBSTITUTED TENOIMIDAZOLE DERIVATIVES. |
JP2662754B2 (en) * | 1992-07-20 | 1997-10-15 | 新日本製鐵株式会社 | Backing steel material for tank bottom plate welding and corrosion prevention method for tank bottom plate |
-
1988
- 1988-08-11 DE DE3827276A patent/DE3827276A1/en not_active Withdrawn
- 1988-08-11 TN TNTNSN88083A patent/TNSN88083A1/en unknown
- 1988-08-11 FI FI883738A patent/FI89602C/en not_active IP Right Cessation
- 1988-08-11 EP EP88113055A patent/EP0304732A3/en not_active Withdrawn
- 1988-08-11 MA MA21595A patent/MA21352A1/en unknown
- 1988-08-12 CA CA000574551A patent/CA1268461A/en not_active Expired - Fee Related
- 1988-08-12 DK DK454588A patent/DK454588A/en not_active Application Discontinuation
- 1988-08-12 NZ NZ225805A patent/NZ225805A/en unknown
- 1988-08-12 NO NO883610A patent/NO167511C/en unknown
- 1988-08-12 JP JP63200279A patent/JPS6470492A/en active Pending
- 1988-08-12 IL IL87428A patent/IL87428A/en not_active IP Right Cessation
- 1988-08-12 PT PT88258A patent/PT88258B/en active IP Right Grant
- 1988-08-13 CN CN88106299A patent/CN1029973C/en not_active Expired - Fee Related
- 1988-08-13 KR KR1019880010337A patent/KR890003772A/en not_active Application Discontinuation
- 1988-08-15 HU HU884355A patent/HU208539B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0304732A3 (en) | 1990-06-13 |
DK454588D0 (en) | 1988-08-12 |
HUT50480A (en) | 1990-02-28 |
NO883610D0 (en) | 1988-08-12 |
FI883738A0 (en) | 1988-08-11 |
NZ225805A (en) | 1991-01-29 |
NO883610L (en) | 1989-02-16 |
DE3827276A1 (en) | 1989-03-23 |
HU208539B (en) | 1993-11-29 |
EP0304732A2 (en) | 1989-03-01 |
MA21352A1 (en) | 1989-04-01 |
IL87428A0 (en) | 1989-01-31 |
NO167511C (en) | 1991-11-13 |
CN1029973C (en) | 1995-10-11 |
IL87428A (en) | 1993-01-31 |
CN1032340A (en) | 1989-04-12 |
FI89602C (en) | 1993-10-25 |
FI883738A (en) | 1989-02-16 |
CA1268461A (en) | 1990-05-01 |
FI89602B (en) | 1993-07-15 |
PT88258B (en) | 1995-05-04 |
TNSN88083A1 (en) | 1990-07-10 |
KR890003772A (en) | 1989-04-18 |
PT88258A (en) | 1989-06-30 |
JPS6470492A (en) | 1989-03-15 |
DK454588A (en) | 1989-02-16 |
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