NO165148C - Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av tricykliske aminosyrer. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av tricykliske aminosyrer.

Info

Publication number: NO165148C
Authority: NO; Norway
Prior art keywords: preparation; amino acids; active derivatives; therapeutic active; analogy procedure
Prior art date: 1982-11-13

Application number

NO834128A

Other languages

English (en)

Other versions

NO165148B (no

NO834128L (no

Inventor

Hansjoerg Urbach

Rainer Hennig

Reinhard Becker

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-13

Filing date

1983-11-11

Publication date

1991-01-09

1983-11-11 Application filed by Hoechst Ag filed Critical Hoechst Ag

1984-05-14 Publication of NO834128L publication Critical patent/NO834128L/no

1990-09-24 Publication of NO165148B publication Critical patent/NO165148B/no

1991-01-09 Publication of NO165148C publication Critical patent/NO165148C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO834128A 1982-11-13 1983-11-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av tricykliske aminosyrer. NO165148C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19823242151 DE3242151A1 (de)	1982-11-13	1982-11-13	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

Publications (3)

Publication Number	Publication Date
NO834128L NO834128L (no)	1984-05-14
NO165148B NO165148B (no)	1990-09-24
NO165148C true NO165148C (no)	1991-01-09

Family

ID=6178144

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO834128A NO165148C (no)	1982-11-13	1983-11-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av tricykliske aminosyrer.

Country Status (22)

Country	Link
US (2)	US4558065A (no)
EP (1)	EP0109020B1 (no)
JP (1)	JPS59101463A (no)
KR (1)	KR910000255B1 (no)
AR (2)	AR241474A1 (no)
AT (1)	ATE29889T1 (no)
AU (2)	AU565264B2 (no)
CA (1)	CA1246554A (no)
DE (2)	DE3242151A1 (no)
DK (1)	DK160983C (no)
ES (3)	ES527182A0 (no)
FI (1)	FI79116C (no)
GR (1)	GR78734B (no)
HU (1)	HU188978B (no)
IE (1)	IE56230B1 (no)
IL (1)	IL70207A (no)
MA (1)	MA19951A1 (no)
NO (1)	NO165148C (no)
NZ (1)	NZ206236A (no)
PH (1)	PH19675A (no)
PT (1)	PT77652B (no)
ZA (1)	ZA838378B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3226768A1 (de) *	1981-11-05	1983-05-26	Hoechst Ag, 6230 Frankfurt	Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) *	1981-12-29	1991-02-14	Hoechst Ag	New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
DE3242151A1 (de) *	1982-11-13	1984-05-17	Hoechst Ag, 6230 Frankfurt	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US5175306A (en) *	1983-01-31	1992-12-29	Hoechst Aktiengesellschaft	Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3303344A1 (de)	1983-02-02	1984-08-02	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3333455A1 (de) *	1983-09-16	1985-04-11	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) *	1984-04-12	1997-11-04	Hoechst Aktiengesellschaft	Method of treating cardiac insufficiency
DE3413710A1 (de) *	1984-04-12	1985-10-24	Hoechst Ag, 6230 Frankfurt	Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) *	1984-08-28	1986-03-06	Hoechst Ag, 6230 Frankfurt	Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US4678802A (en) *	1985-07-09	1987-07-07	Pfizer Inc.	1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
US5231080A (en) *	1985-10-15	1993-07-27	Hoechst Aktiengesellschaft	Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) *	1986-03-27	1993-07-27	Hoechst Aktiengesellschaft	Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) *	1986-10-02	1988-04-14	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) *	1986-11-21	1988-06-01	Hoechst Ag	Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) *	1987-07-03	1989-01-12	Hoechst Ag	Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) *	1988-04-22	1991-01-28	Hoechst Ag	Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DD284030A5 (de)	1988-11-24	1990-10-31	Hoechst Ag,De	Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
LT3872B (en)	1993-12-06	1996-04-25	Hoechst Ag	Novel peptides and pharmaceutical compositions containing them
FR2746394B1 (fr)	1996-03-20	1998-05-29	Roussel Uclaf	Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
ES2171768T3 (es)	1996-03-20	2002-09-16	Hoechst Ag	Inhibidores de la resorcion osea y antagonistas de receptores de vitronectina.
DE19653647A1 (de)	1996-12-20	1998-06-25	Hoechst Ag	Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de)	1997-09-18	1999-03-25	Hoechst Marion Roussel De Gmbh	Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) *	1997-09-23	1999-03-25	Hoechst Marion Roussel De Gmbh	Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de)	1997-11-19	1999-05-20	Hoechst Marion Roussel De Gmbh	Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de)	1998-05-14	1999-11-18	Hoechst Marion Roussel De Gmbh	Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
CA2521364A1 (en) *	2003-04-15	2004-10-28	Warner-Lambert Company Llc	[c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
CA2522195A1 (en) *	2003-04-15	2004-10-28	Warner-Lambert Company Llc	[b]-fused bicyclic proline derivatives and their use for treating arthritic conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4060626A (en) *	1972-01-26	1977-11-29	Boehringer Mannheim G.M.B.H.	Indole-carboxylic carbon compounds and pharmaceutical compositions containing them
FR2491469A1 (fr) *	1980-10-02	1982-04-09	Science Union & Cie	Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3118191A1 (de) *	1981-05-08	1982-11-25	Hoechst Ag, 6000 Frankfurt	Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
EP0050800B2 (en) *	1980-10-23	1995-06-07	Schering Corporation	Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4431645A (en) *	1982-03-08	1984-02-14	Schering Corporation	Antihypertensive agents
US4431644A (en) *	1982-03-08	1984-02-14	Schering Corporation	Antihypertensive agents
EP0088350B1 (en) *	1982-03-08	1985-02-20	Schering Corporation	Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
DE3242151A1 (de) *	1982-11-13	1984-05-17	Hoechst Ag, 6230 Frankfurt	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

1982
- 1982-11-13 DE DE19823242151 patent/DE3242151A1/de not_active Withdrawn
1983
- 1983-11-07 AT AT83111079T patent/ATE29889T1/de not_active IP Right Cessation
- 1983-11-07 EP EP83111079A patent/EP0109020B1/de not_active Expired
- 1983-11-07 DE DE8383111079T patent/DE3373818D1/de not_active Expired
- 1983-11-08 HU HU833828A patent/HU188978B/hu not_active IP Right Cessation
- 1983-11-10 US US06/550,531 patent/US4558065A/en not_active Expired - Lifetime
- 1983-11-10 FI FI834131A patent/FI79116C/fi not_active IP Right Cessation
- 1983-11-10 ZA ZA838378A patent/ZA838378B/xx unknown
- 1983-11-11 PT PT77652A patent/PT77652B/pt not_active IP Right Cessation
- 1983-11-11 IE IE2633/83A patent/IE56230B1/en not_active IP Right Cessation
- 1983-11-11 IL IL70207A patent/IL70207A/xx not_active IP Right Cessation
- 1983-11-11 DK DK516583A patent/DK160983C/da active
- 1983-11-11 PH PH29818A patent/PH19675A/en unknown
- 1983-11-11 NZ NZ206236A patent/NZ206236A/en unknown
- 1983-11-11 ES ES527182A patent/ES527182A0/es active Granted
- 1983-11-11 MA MA20172A patent/MA19951A1/fr unknown
- 1983-11-11 AR AR83294785A patent/AR241474A1/es active
- 1983-11-11 NO NO834128A patent/NO165148C/no not_active IP Right Cessation
- 1983-11-11 GR GR72949A patent/GR78734B/el unknown
- 1983-11-11 AU AU21197/83A patent/AU565264B2/en not_active Ceased
- 1983-11-11 JP JP58211141A patent/JPS59101463A/ja active Granted
- 1983-11-11 KR KR1019830005346A patent/KR910000255B1/ko not_active IP Right Cessation
- 1983-11-14 CA CA000441040A patent/CA1246554A/en not_active Expired
1984
- 1984-01-20 ES ES529030A patent/ES529030A0/es active Granted
- 1984-01-20 ES ES529037A patent/ES529037A0/es active Granted
1985
- 1985-05-17 AR AR85300427A patent/AR243506A1/es active
- 1985-09-06 US US06/773,077 patent/US4614805A/en not_active Expired - Lifetime
1987
- 1987-02-06 AU AU68597/87A patent/AU584273B2/en not_active Ceased

Also Published As

Publication number	Publication date
ES8500230A1 (es)	1984-10-01
CA1246554A (en)	1988-12-13
ZA838378B (en)	1984-06-27
PT77652B (de)	1986-04-17
ATE29889T1 (de)	1987-10-15
FI79116B (fi)	1989-07-31
FI834131A0 (fi)	1983-11-10
GR78734B (no)	1984-10-02
EP0109020A2 (de)	1984-05-23
PH19675A (en)	1986-06-09
IL70207A (en)	1988-12-30
DK516583A (da)	1984-05-14
DK516583D0 (da)	1983-11-11
NZ206236A (en)	1988-03-30
IL70207A0 (en)	1984-02-29
AR241474A1 (es)	1992-07-31
EP0109020A3 (en)	1985-07-17
US4558065A (en)	1985-12-10
DK160983C (da)	1991-10-28
DE3242151A1 (de)	1984-05-17
ES8406438A1 (es)	1984-08-01
IE56230B1 (en)	1991-05-22
MA19951A1 (fr)	1984-07-01
AU6859787A (en)	1987-05-07
ES529037A0 (es)	1984-10-01
FI79116C (fi)	1989-11-10
EP0109020B1 (de)	1987-09-23
KR840006623A (ko)	1984-12-01
AR243506A1 (es)	1993-08-31
JPH0472839B2 (no)	1992-11-19
ES8500229A1 (es)	1984-10-01
NO165148B (no)	1990-09-24
DK160983B (da)	1991-05-13
NO834128L (no)	1984-05-14
IE832633L (en)	1984-05-13
KR910000255B1 (ko)	1991-01-23
AU2119783A (en)	1984-05-17
JPS59101463A (ja)	1984-06-12
AU565264B2 (en)	1987-09-10
US4614805A (en)	1986-09-30
ES529030A0 (es)	1984-10-01
FI834131A (fi)	1984-05-14
PT77652A (de)	1983-12-01
ES527182A0 (es)	1984-08-01
HU188978B (en)	1986-05-28
AU584273B2 (en)	1989-05-18
DE3373818D1 (en)	1987-10-29

Legal Events

Date	Code	Title	Description
2002-07-08	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN MAY 2002

Publication	Publication Date	Title
NO165148C (no)	1991-01-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av tricykliske aminosyrer.
NO156786C (no)	1987-11-25	Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av bicykliske aminosyrer.
NO163406C (no)	1990-05-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazokinolinonderivater.
NO162764C (no)	1990-02-14	Analogifremgangsmaate for fremstilling av terapeutisk aktive indolinderivater.
NO862477D0 (no)	1986-06-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-arylimidazol-derivater.
NO832431L (no)	1984-01-06	Fremgangsmaate for fremstilling av terapeutisk aktive karbostyril-derivater.
NO165239C (no)	1991-01-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzyl-aminoalkyl-pyrrolidinon-derivater.
NO162856C (no)	1990-02-28	Analogifremgangsmaate til fremstilling av nye terapeutisk aktive bisykliske aminosyrer.
NO165192C (no)	1991-01-09	Analogifremgangsmaate for fremstilling av terapeutisk aktive glyserolderivater.
NO831610L (no)	1983-11-09	Fremgangsmaate for fremstilling av terapeutisk aktive oxicamderivater.
NO161562C (no)	1989-08-30	Analogifremgangsmaate for fremstilling av terapeutisk aktive ergolinderivater.
NO161676C (no)	1989-09-13	Analogifremgangsm te til fremstilling av terapeutisk aktive mitosanderivater.
NO840212L (no)	1984-07-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyre-derivater
NO870049L (no)	1987-07-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO161559C (no)	1989-08-30	Analogifremgangsmaate til fremstilling av terapeutisk aktive triazolderivater.
NO164897C (no)	1990-11-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive oxazolidinonderivater.
NO164982C (no)	1990-12-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater.
NO158941C (no)	1988-11-16	Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-piperidino-kinazolinderivater.
NO160079C (no)	1989-03-08	Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-derivater.
NO158739C (no)	1988-10-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-piperazinopyrimidinderivater.
NO160511C (no)	1989-04-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive fenyl-cyklo-butanderivater.
NO830900L (no)	1983-09-19	Fremgangsmaate for fremstilling av terapeutisk aktive tricykliske derivater.
NO168478C (no)	1992-02-26	Analogifremgangsmaate for fremstilling av terapeutisk aktive vinylthioacetamido-oxacefalosporinderivater.
NO164895C (no)	1990-11-28	Analogifremgangsmaate for fremstilling av terapeutisk aktive dikloranilinderivater.
NO167802C (no)	1991-12-11	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepinderivater.