ES529037A0 - Procedimiento para preparar nuevos derivados de aminoacidos triciclicos - Google Patents

Procedimiento para preparar nuevos derivados de aminoacidos triciclicos

Info

Publication number: ES529037A0
Authority: ES; Spain
Prior art keywords: procedure; amino acid; acid derivatives; preparing new; new tricyclic
Prior art date: 1982-11-13
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES529037A

Other languages

English (en)

Other versions

ES8500230A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hoechst AG

Original Assignee

Hoechst AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-13

Filing date

1984-01-20

Publication date

1984-10-01

1984-01-20 Application filed by Hoechst AG filed Critical Hoechst AG

1984-10-01 Publication of ES529037A0 publication Critical patent/ES529037A0/es

1984-10-01 Publication of ES8500230A1 publication Critical patent/ES8500230A1/es

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

ES529037A 1982-11-13 1984-01-20 Procedimiento para preparar nuevos derivados de aminoacidos triciclicos Expired ES8500230A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19823242151 DE3242151A1 (de)	1982-11-13	1982-11-13	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

Publications (2)

Publication Number	Publication Date
ES529037A0 true ES529037A0 (es)	1984-10-01
ES8500230A1 ES8500230A1 (es)	1984-10-01

Family

ID=6178144

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
ES527182A Granted ES527182A0 (es)	1982-11-13	1983-11-11	Procedimiento para preparar nuevos derivados de aminoacidos triciclicos
ES529030A Granted ES529030A0 (es)	1982-11-13	1984-01-20	Procedimiento para preparar derivados de aminoacidos triciclicos
ES529037A Expired ES8500230A1 (es)	1982-11-13	1984-01-20	Procedimiento para preparar nuevos derivados de aminoacidos triciclicos

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
ES527182A Granted ES527182A0 (es)	1982-11-13	1983-11-11	Procedimiento para preparar nuevos derivados de aminoacidos triciclicos
ES529030A Granted ES529030A0 (es)	1982-11-13	1984-01-20	Procedimiento para preparar derivados de aminoacidos triciclicos

Country Status (22)

Country	Link
US (2)	US4558065A (es)
EP (1)	EP0109020B1 (es)
JP (1)	JPS59101463A (es)
KR (1)	KR910000255B1 (es)
AR (2)	AR241474A1 (es)
AT (1)	ATE29889T1 (es)
AU (2)	AU565264B2 (es)
CA (1)	CA1246554A (es)
DE (2)	DE3242151A1 (es)
DK (1)	DK160983C (es)
ES (3)	ES527182A0 (es)
FI (1)	FI79116C (es)
GR (1)	GR78734B (es)
HU (1)	HU188978B (es)
IE (1)	IE56230B1 (es)
IL (1)	IL70207A (es)
MA (1)	MA19951A1 (es)
NO (1)	NO165148C (es)
NZ (1)	NZ206236A (es)
PH (1)	PH19675A (es)
PT (1)	PT77652B (es)
ZA (1)	ZA838378B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3226768A1 (de) *	1981-11-05	1983-05-26	Hoechst Ag, 6230 Frankfurt	Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
IE55867B1 (en) *	1981-12-29	1991-02-14	Hoechst Ag	New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
DE3242151A1 (de) *	1982-11-13	1984-05-17	Hoechst Ag, 6230 Frankfurt	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
US5175306A (en) *	1983-01-31	1992-12-29	Hoechst Aktiengesellschaft	Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
DE3303344A1 (de)	1983-02-02	1984-08-02	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
DE3333455A1 (de) *	1983-09-16	1985-04-11	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung n-alkylierter dipeptide und deren estern
US5684016A (en) *	1984-04-12	1997-11-04	Hoechst Aktiengesellschaft	Method of treating cardiac insufficiency
DE3413710A1 (de) *	1984-04-12	1985-10-24	Hoechst Ag, 6230 Frankfurt	Verfahren zur behandlung der herzinsuffizienz
DE3431541A1 (de) *	1984-08-28	1986-03-06	Hoechst Ag, 6230 Frankfurt	Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US4678802A (en) *	1985-07-09	1987-07-07	Pfizer Inc.	1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
US5231080A (en) *	1985-10-15	1993-07-27	Hoechst Aktiengesellschaft	Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
US5231084A (en) *	1986-03-27	1993-07-27	Hoechst Aktiengesellschaft	Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) *	1986-10-02	1988-04-14	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) *	1986-11-21	1988-06-01	Hoechst Ag	Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) *	1987-07-03	1989-01-12	Hoechst Ag	Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) *	1988-04-22	1991-01-28	Hoechst Ag	Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DD284030A5 (de)	1988-11-24	1990-10-31	Hoechst Ag,De	Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
LT3872B (en)	1993-12-06	1996-04-25	Hoechst Ag	Novel peptides and pharmaceutical compositions containing them
FR2746394B1 (fr)	1996-03-20	1998-05-29	Roussel Uclaf	Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
PT796855E (pt)	1996-03-20	2002-07-31	Hoechst Ag	Inibicao da reabsorcao nos ossos e antagonistas de vitronectina
DE19653647A1 (de)	1996-12-20	1998-06-25	Hoechst Ag	Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de)	1997-09-18	1999-03-25	Hoechst Marion Roussel De Gmbh	Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) *	1997-09-23	1999-03-25	Hoechst Marion Roussel De Gmbh	Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de)	1997-11-19	1999-05-20	Hoechst Marion Roussel De Gmbh	Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
DE19821483A1 (de)	1998-05-14	1999-11-18	Hoechst Marion Roussel De Gmbh	Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
WO2004092134A1 (en) *	2003-04-15	2004-10-28	Warner-Lambert Company Llc	[c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
MXPA05011168A (es) *	2003-04-15	2005-12-14	Warner Lambert Co	Derivados de prolina biciclicos [b]-condensados y sus usos para tratar afecciones artriticas.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4060626A (en) *	1972-01-26	1977-11-29	Boehringer Mannheim G.M.B.H.	Indole-carboxylic carbon compounds and pharmaceutical compositions containing them
FR2491469A1 (fr) *	1980-10-02	1982-04-09	Science Union & Cie	Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3118191A1 (de) *	1981-05-08	1982-11-25	Hoechst Ag, 6000 Frankfurt	Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
EP0050800B2 (en) *	1980-10-23	1995-06-07	Schering Corporation	Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4431644A (en) *	1982-03-08	1984-02-14	Schering Corporation	Antihypertensive agents
DE3360065D1 (en) *	1982-03-08	1985-03-28	Schering Corp	Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
US4431645A (en) *	1982-03-08	1984-02-14	Schering Corporation	Antihypertensive agents
DE3242151A1 (de) *	1982-11-13	1984-05-17	Hoechst Ag, 6230 Frankfurt	Neue derivate tricyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung, sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung

1982
- 1982-11-13 DE DE19823242151 patent/DE3242151A1/de not_active Withdrawn
1983
- 1983-11-07 EP EP83111079A patent/EP0109020B1/de not_active Expired
- 1983-11-07 AT AT83111079T patent/ATE29889T1/de not_active IP Right Cessation
- 1983-11-07 DE DE8383111079T patent/DE3373818D1/de not_active Expired
- 1983-11-08 HU HU833828A patent/HU188978B/hu not_active IP Right Cessation
- 1983-11-10 ZA ZA838378A patent/ZA838378B/xx unknown
- 1983-11-10 US US06/550,531 patent/US4558065A/en not_active Expired - Lifetime
- 1983-11-10 FI FI834131A patent/FI79116C/fi not_active IP Right Cessation
- 1983-11-11 JP JP58211141A patent/JPS59101463A/ja active Granted
- 1983-11-11 IE IE2633/83A patent/IE56230B1/en not_active IP Right Cessation
- 1983-11-11 AU AU21197/83A patent/AU565264B2/en not_active Ceased
- 1983-11-11 PT PT77652A patent/PT77652B/pt not_active IP Right Cessation
- 1983-11-11 IL IL70207A patent/IL70207A/xx not_active IP Right Cessation
- 1983-11-11 PH PH29818A patent/PH19675A/en unknown
- 1983-11-11 ES ES527182A patent/ES527182A0/es active Granted
- 1983-11-11 GR GR72949A patent/GR78734B/el unknown
- 1983-11-11 DK DK516583A patent/DK160983C/da active
- 1983-11-11 NO NO834128A patent/NO165148C/no not_active IP Right Cessation
- 1983-11-11 NZ NZ206236A patent/NZ206236A/en unknown
- 1983-11-11 MA MA20172A patent/MA19951A1/fr unknown
- 1983-11-11 AR AR83294785A patent/AR241474A1/es active
- 1983-11-11 KR KR1019830005346A patent/KR910000255B1/ko not_active IP Right Cessation
- 1983-11-14 CA CA000441040A patent/CA1246554A/en not_active Expired
1984
- 1984-01-20 ES ES529030A patent/ES529030A0/es active Granted
- 1984-01-20 ES ES529037A patent/ES8500230A1/es not_active Expired
1985
- 1985-05-17 AR AR85300427A patent/AR243506A1/es active
- 1985-09-06 US US06/773,077 patent/US4614805A/en not_active Expired - Lifetime
1987
- 1987-02-06 AU AU68597/87A patent/AU584273B2/en not_active Ceased

Also Published As

Publication number	Publication date
IL70207A (en)	1988-12-30
NZ206236A (en)	1988-03-30
IL70207A0 (en)	1984-02-29
JPS59101463A (ja)	1984-06-12
EP0109020A2 (de)	1984-05-23
DK516583A (da)	1984-05-14
EP0109020B1 (de)	1987-09-23
ES8406438A1 (es)	1984-08-01
ES8500229A1 (es)	1984-10-01
KR910000255B1 (ko)	1991-01-23
PH19675A (en)	1986-06-09
DK516583D0 (da)	1983-11-11
DK160983C (da)	1991-10-28
AU2119783A (en)	1984-05-17
IE56230B1 (en)	1991-05-22
NO834128L (no)	1984-05-14
HU188978B (en)	1986-05-28
DE3242151A1 (de)	1984-05-17
ZA838378B (en)	1984-06-27
ATE29889T1 (de)	1987-10-15
JPH0472839B2 (es)	1992-11-19
US4614805A (en)	1986-09-30
IE832633L (en)	1984-05-13
CA1246554A (en)	1988-12-13
AU565264B2 (en)	1987-09-10
FI79116B (fi)	1989-07-31
AU6859787A (en)	1987-05-07
AR243506A1 (es)	1993-08-31
AU584273B2 (en)	1989-05-18
PT77652B (de)	1986-04-17
PT77652A (de)	1983-12-01
NO165148B (no)	1990-09-24
FI834131A (fi)	1984-05-14
MA19951A1 (fr)	1984-07-01
ES527182A0 (es)	1984-08-01
US4558065A (en)	1985-12-10
ES529030A0 (es)	1984-10-01
FI79116C (fi)	1989-11-10
AR241474A1 (es)	1992-07-31
DE3373818D1 (en)	1987-10-29
NO165148C (no)	1991-01-09
EP0109020A3 (en)	1985-07-17
DK160983B (da)	1991-05-13
FI834131A0 (fi)	1983-11-10
ES8500230A1 (es)	1984-10-01
KR840006623A (ko)	1984-12-01
GR78734B (es)	1984-10-02

Publication	Publication Date	Title
ES529037A0 (es)	1984-10-01	Procedimiento para preparar nuevos derivados de aminoacidos triciclicos
ES532765A0 (es)	1985-01-16	Procedimiento para preparar derivados de 3-bencilidenalcanfor
MX156053A (es)	1988-06-22	Procedimiento para preparar derivados de 1-fenil-2-piperidino-propanol
ES504955A0 (es)	1982-08-16	Procedimiento para la preparacion de derivados de aminoacidos
MX7199E (es)	1987-12-23	Procedimiento para preparar derivados de 3-cetodelta-4,9,19-nor-esteroides
ES521041A0 (es)	1984-01-01	Procedimiento para la preparacion de nuevos derivados de aminoacidos biciclicos.
ES535527A0 (es)	1985-07-16	Procedimiento para preparar derivados de piperazina
ES520802A0 (es)	1986-05-16	Procedimiento para la preparacion de nuevos derivados de aminoacidos biciclicos.
MX161088A (es)	1990-07-25	Procedimiento para preparar derivados de 1-metil-5-p-tolilpirrol-2-acetamida
ES529035A0 (es)	1985-04-16	Procedimiento para preparar derivados de aminoacidos
MX156348A (es)	1988-08-09	Procedimiento para la preparacion de derivados de acidos omega-aminocanoicos
ES523938A0 (es)	1984-11-01	Procedimiento para preparar n-fosfonometilglicina
ES539313A0 (es)	1986-04-01	Procedimiento para preparar derivados de n-fenilpirazol
MX157788A (es)	1988-12-15	Procedimiento para preparar derivados de oxima
ES522786A0 (es)	1985-02-01	Procedimiento para preparar derivados de piperacina.
ES524830A0 (es)	1985-01-16	Procedimiento para preparar derivados de xantina
ES527164A0 (es)	1985-05-01	Procedimiento para preparar derivados de 2-piperacinil-quinazolina
ES521847A0 (es)	1984-08-01	Procedimiento para preparar derivados de pleuromutilina
ES525714A0 (es)	1986-04-01	Procedimiento para preparar acidos fenoxialcanoicos
ES525085A0 (es)	1985-01-16	Procedimiento para preparar n-alil-olalquil-tionocarbamatos
ES525235A0 (es)	1985-01-16	Procedimiento para preparar n-fosfonometilglicina
ES523937A0 (es)	1984-11-01	Procedimiento para preparar derivados de bencimidazol
ES555389A0 (es)	1987-07-01	Procedimiento para preparar derivados de aminoacidos
ES529074A0 (es)	1985-05-16	Procedimiento para preparar derivados de quinazolina
MX162511A (es)	1991-05-15	Procedimiento para preparar derivados de tetrahidronaftaleno