NO156694C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider.

Info

Publication number: NO156694C
Authority: NO; Norway
Prior art keywords: propadienyl; steroids; preparation; therapeutic active; analogy procedure
Prior art date: 1980-06-27

Application number

NO81812509A

Other languages

English (en)

Other versions

NO812509L (no

NO156694B (no

Inventor

Brian W Metcalf

J O Neal Johnston

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-06-27

Filing date

1981-07-22

Publication date

1987-11-04

1981-07-22 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1981-07-22 Priority to NO81812509A priority Critical patent/NO156694C/no

1983-01-24 Publication of NO812509L publication Critical patent/NO812509L/no

1986-04-29 Priority to NO86861695A priority patent/NO158380C/no

1987-07-27 Publication of NO156694B publication Critical patent/NO156694B/no

1987-11-04 Publication of NO156694C publication Critical patent/NO156694C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO81812509A 1980-06-27 1981-07-22 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider. NO156694C (no)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
NO81812509A NO156694C (no)	1980-06-27	1981-07-22	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider.
NO86861695A NO158380C (no)	1980-06-27	1986-04-29	Nye 10-(1,2-propadienyl)steroider og antikonsepsjonsmidler inneholdende disse.

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/163,453 US4289762A (en)	1980-06-27	1980-06-27	10-(1,2-Propadienyl) steroids as irreversible aromatase inhibitors
NO81812509A NO156694C (no)	1980-06-27	1981-07-22	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider.

Publications (3)

Publication Number	Publication Date
NO812509L NO812509L (no)	1983-01-24
NO156694B NO156694B (no)	1987-07-27
NO156694C true NO156694C (no)	1987-11-04

Family

ID=22590073

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO81812509A NO156694C (no)	1980-06-27	1981-07-22	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 10-(1,2-propadienyl)-steroider.

Country Status (21)

Country	Link
US (1)	US4289762A (no)
JP (1)	JPS5738798A (no)
AT (1)	AT377989B (no)
AU (1)	AU539215B2 (no)
BE (1)	BE889404A (no)
CA (1)	CA1173432A (no)
CH (1)	CH647532A5 (no)
DE (1)	DE3124719C2 (no)
DK (1)	DK163129C (no)
ES (1)	ES8400449A1 (no)
FR (1)	FR2485544A1 (no)
GB (1)	GB2078750B (no)
IE (1)	IE51352B1 (no)
IL (1)	IL63142A0 (no)
IT (1)	IT1171340B (no)
NL (1)	NL8103098A (no)
NO (1)	NO156694C (no)
NZ (1)	NZ197495A (no)
PH (1)	PH16690A (no)
SE (1)	SE448878B (no)
ZA (1)	ZA814219B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100566B1 (en) *	1982-07-14	1986-02-19	Akzo N.V.	Novel 19-thio-androstane derivatives
US4495102A (en) *	1982-09-03	1985-01-22	G. D. Searle & Co.	Aminoalkyl steroids
EP0114033B1 (de) *	1982-12-21	1988-10-12	Ciba-Geigy Ag	Substituierte Azabicycloalkane, ihre Verwendung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verfahren zur Herstellung dieser Verbindungen
DE3323321A1 (de) *	1983-06-24	1985-01-03	Schering AG, 1000 Berlin und 4709 Bergkamen	Prophylaxe und therapie von koronaren herzkrankheiten durch senkung des oestrogenspiegels
US4634694A (en) *	1984-01-14	1987-01-06	Akzo N.V.	Novel Δ4 - and Δ5 -androstene derivatives and pharmaceutical compositions containing these derivatives
GB8531747D0 (en) *	1985-12-24	1986-02-05	Erba Farmitalia	10beta-alkynylestrene derivatives
GB8624251D0 (en) *	1986-10-09	1986-11-12	Erba Farmitalia	"1,2-beta-methylene-4-substituted androstene-3,17 dione derivatives
DE3705990A1 (de) *	1987-02-20	1988-09-01	Schering Ag	1-methyl-15(alpha)-(1-oxyalkyl)-androsta-1,4-dien- 3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3714965A1 (de) *	1987-04-30	1988-11-10	Schering Ag	3-methylen-4-androsten-17-one, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
US4910191A (en) *	1988-06-28	1990-03-20	Merrell Dow Pharmaceuticals Inc.	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
CH683151A5 (de) *	1991-04-24	1994-01-31	Ciba Geigy Ag	Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
DE4435368A1 (de) *	1994-09-22	1996-03-28	Schering Ag	Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
EP1708169A1 (en)	1995-02-01	2006-10-04	Seiko Epson Corporation	Driving circuit and active matrix substrate and liquid crystal display device including it
PL366554A1 (en) *	2001-04-17	2005-02-07	Ares Trading S.A.	Aromatase inhibition to enhance assisted reproduction
DE10141937A1 (de) *	2001-08-28	2003-03-27	Alfred Schmidt	Markierung der Aromatase
EP1854465A1 (en) *	2006-05-12	2007-11-14	Alexander Tobias Teichmann	Use of 4,17 beta-dihydroxyandrost-4-ene-3-one for treating cancers
WO2011127232A2 (en)	2010-04-08	2011-10-13	Emory University	Substituted androst-4-ene diones
EP3666276A1 (en)	2018-12-14	2020-06-17	dcic Biopharmaceutical Limited	Medication against estrogen-receptor beta (erbeta) positive breast tumor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3102127A (en) *	1962-06-12	1963-08-27	Syntex Corp	19-methylene-androstane derivatives
FR1519387A (fr) *	1966-04-20	1968-03-29	Hoffmann La Roche	Procédé pour la préparation de 19-alcényl-stéroïdes
DE2310963A1 (de) *	1972-04-14	1974-09-05	Schering Ag	Methode zur kontrazeption durch verabfolgung von stufenkombinationspraeparaten
CH606101A5 (no) *	1975-01-30	1978-10-13	Ciba Geigy Ag

1980
- 1980-06-27 US US06/163,453 patent/US4289762A/en not_active Expired - Lifetime
1981
- 1981-06-22 IL IL63142A patent/IL63142A0/xx not_active IP Right Cessation
- 1981-06-22 ZA ZA814219A patent/ZA814219B/xx unknown
- 1981-06-22 CA CA000380342A patent/CA1173432A/en not_active Expired
- 1981-06-22 NZ NZ197495A patent/NZ197495A/en unknown
- 1981-06-22 PH PH25799A patent/PH16690A/en unknown
- 1981-06-24 DE DE3124719A patent/DE3124719C2/de not_active Expired - Fee Related
- 1981-06-25 SE SE8103988A patent/SE448878B/sv not_active IP Right Cessation
- 1981-06-25 CH CH4213/81A patent/CH647532A5/de not_active IP Right Cessation
- 1981-06-26 NL NL8103098A patent/NL8103098A/nl not_active Application Discontinuation
- 1981-06-26 IT IT8148781A patent/IT1171340B/it active
- 1981-06-26 DK DK284481A patent/DK163129C/da not_active IP Right Cessation
- 1981-06-26 ES ES503451A patent/ES8400449A1/es not_active Expired
- 1981-06-26 FR FR8112643A patent/FR2485544A1/fr active Granted
- 1981-06-26 IE IE1435/81A patent/IE51352B1/en not_active IP Right Cessation
- 1981-06-26 AT AT0285881A patent/AT377989B/de not_active IP Right Cessation
- 1981-06-26 GB GB8119814A patent/GB2078750B/en not_active Expired
- 1981-06-26 BE BE0/205232A patent/BE889404A/fr not_active IP Right Cessation
- 1981-06-27 JP JP9909781A patent/JPS5738798A/ja active Granted
- 1981-06-30 AU AU72369/81A patent/AU539215B2/en not_active Ceased
- 1981-07-22 NO NO81812509A patent/NO156694C/no unknown

Also Published As

Publication number	Publication date
IE811435L (en)	1981-12-27
AT377989B (de)	1985-05-28
DE3124719A1 (de)	1982-03-18
US4289762A (en)	1981-09-15
DK163129C (da)	1992-06-09
JPS5738798A (en)	1982-03-03
DK284481A (da)	1981-12-28
ATA285881A (de)	1984-10-15
PH16690A (en)	1984-01-06
AU539215B2 (en)	1984-09-13
ZA814219B (en)	1982-07-28
NO812509L (no)	1983-01-24
ES503451A0 (es)	1983-11-01
IT8148781A0 (it)	1981-06-26
SE448878B (sv)	1987-03-23
AU7236981A (en)	1982-01-07
DE3124719C2 (de)	1994-03-03
ES8400449A1 (es)	1983-11-01
CH647532A5 (de)	1985-01-31
GB2078750A (en)	1982-01-13
FR2485544A1 (fr)	1981-12-31
IE51352B1 (en)	1986-12-10
CA1173432A (en)	1984-08-28
GB2078750B (en)	1984-08-22
NL8103098A (nl)	1982-01-18
NO156694B (no)	1987-07-27
IL63142A0 (en)	1981-09-13
DK163129B (da)	1992-01-20
JPH0121158B2 (no)	1989-04-19
SE8103988L (sv)	1981-12-28
BE889404A (fr)	1981-12-28
NZ197495A (en)	1985-01-31
IT1171340B (it)	1987-06-10
FR2485544B1 (no)	1983-12-16

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