NO153689C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner.

Info

Publication number
NO153689C
NO153689C NO774524A NO774524A NO153689C NO 153689 C NO153689 C NO 153689C NO 774524 A NO774524 A NO 774524A NO 774524 A NO774524 A NO 774524A NO 153689 C NO153689 C NO 153689C
Authority
NO
Norway
Prior art keywords
prostaglandines
preparation
therapeutically active
analogy procedure
active bicyclic
Prior art date
Application number
NO774524A
Other languages
English (en)
Norwegian (no)
Other versions
NO774524L (no
NO153689B (no
Inventor
Carmelo Gandolfi
Carlo Passarotti
Alessandro Andreoni
Angelo Fumagalli
Franco Faustini
Roberto Ceserani
Maria Maddalena Usardi
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT3104176A external-priority patent/IT1072541B/it
Priority claimed from IT1928377A external-priority patent/IT1079103B/it
Priority claimed from IT2117177A external-priority patent/IT1085878B/it
Priority claimed from IT2141277A external-priority patent/IT1075678B/it
Priority claimed from IT2186377A external-priority patent/IT1115636B/it
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of NO774524L publication Critical patent/NO774524L/no
Publication of NO153689B publication Critical patent/NO153689B/no
Publication of NO153689C publication Critical patent/NO153689C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO774524A 1976-12-31 1977-12-30 Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner. NO153689C (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT3104176A IT1072541B (it) 1976-12-31 1976-12-31 6(9)-ossido-prostenoici acidi
IT1928377A IT1079103B (it) 1977-01-14 1977-01-14 Derivati del 9-ossido-alo-prostanoico acido
IT2117177A IT1085878B (it) 1977-03-14 1977-03-14 Bicilicli ossiranici 15-cheto-prostenoici acidi
IT2141277A IT1075678B (it) 1977-03-21 1977-03-21 15-idrossi-bicicliche prostaglandine
IT2186377A IT1115636B (it) 1977-03-31 1977-03-31 13,14-deidro-bicicliche prostaglandine

Publications (3)

Publication Number Publication Date
NO774524L NO774524L (no) 1978-07-03
NO153689B NO153689B (no) 1986-01-27
NO153689C true NO153689C (no) 1986-05-07

Family

ID=27517783

Family Applications (1)

Application Number Title Priority Date Filing Date
NO774524A NO153689C (no) 1976-12-31 1977-12-30 Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner.

Country Status (19)

Country Link
US (9) US4297368A (it)
JP (1) JPS5384959A (it)
BE (1) BE862514A (it)
CH (1) CH636096A5 (it)
DE (1) DE2757919A1 (it)
DK (1) DK586077A (it)
FI (1) FI71138C (it)
FR (1) FR2376147A1 (it)
GB (1) GB1599280A (it)
GR (1) GR66057B (it)
HU (1) HU182725B (it)
IL (1) IL53630A0 (it)
KE (1) KE3196A (it)
MY (1) MY8200265A (it)
NL (1) NL7714613A (it)
NO (1) NO153689C (it)
NZ (1) NZ185986A (it)
SE (1) SE437268B (it)
YU (1) YU316677A (it)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1053781B (it) * 1974-09-25 1981-10-10 Erba C S P A Ora Farmitalia Omega nor cicloalcil 13.14 deidro prostaglandine
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
HU182583B (en) * 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
IT1088966B (it) * 1977-11-15 1985-06-10 Erba Carlo Spa 13,14-dideidro-prostaglandine
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2
BE871209R (fr) * 1977-12-05 1979-04-12 Upjohn Co Analogues de 5,6-dihydro-prostacycline et leur preparation
IL58384A0 (en) 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE2947526A1 (de) * 1978-11-29 1980-06-12 Ono Pharmaceutical Co Prostacyclin-analoge
US4237060A (en) 1979-03-23 1980-12-02 Hoffmann-La Roche Inc. Prostacyclin analogs
US4235924A (en) 1979-06-07 1980-11-25 American Cyanamid Company Prostacyclin analogs of the 1 series and related analogs wherein the carboxylic acid function has been replaced
US4273718A (en) * 1979-07-05 1981-06-16 The Upjohn Company 2-Decarboxy-2-hydroxymethyl-9-deoxy-6ε,9αepoxy-16,16-difluoro-19-hydroxy-PGF1
US4321203A (en) * 1979-07-05 1982-03-23 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 compounds
US4328156A (en) * 1979-07-05 1982-05-04 The Upjohn Company 19-Hydroxy-19-methyl-7α-homo-PGI1 compounds
US4301079A (en) * 1979-07-05 1981-11-17 The Upjohn Company 19-Hydroxy-19-methyl-PGI1 compounds
US4474966A (en) * 1980-03-03 1984-10-02 The Upjohn Company 19-Hydroxy-7a-homo-PGI1 and 19-hydroxy-19-methyl-7a-homo-PGI1 compounds
DE3035713A1 (de) * 1980-09-22 1982-04-29 F. Hoffmann-La Roche & Co. AG, 4002 Basel Prostacycline
EP0059307A1 (de) 1981-02-26 1982-09-08 Grünenthal GmbH Verfahren zur Herstellung von 2-Oxabicyclo(3.3.0)octanderivaten und danach erhältliche Produkte
CH656877A5 (de) * 1981-11-27 1986-07-31 Erba Farmitalia Optisch aktive oder racemische prostaglandinderivate.
EP0108451A3 (en) * 1982-11-05 1985-04-10 The Procter & Gamble Company Novel prostaglandin analogues
US4576962A (en) * 1983-10-19 1986-03-18 The Procter & Gamble Company Prostaglandin analogues
US5153174A (en) * 1989-10-30 1992-10-06 Union Carbide Chemicals & Plastics Inc. Polymer mixtures useful in skin care
AU9305898A (en) * 1997-09-09 1999-03-29 Procter & Gamble Company, The A process for making prostaglandin f analogs
WO2004089892A2 (en) * 2003-04-01 2004-10-21 Theravance, Inc. Diarylmethyl and related compounds having beta2 andrenergic receptor agonist and muscarinic receptor antagonist activity
US8614340B2 (en) 2009-07-28 2013-12-24 Ono Pharmaceuticals Co., Ltd. Bicyclic compound and use thereof for medical purposes
JP5907077B2 (ja) 2011-01-27 2016-04-20 小野薬品工業株式会社 二環式化合物およびその医薬用途
JP5835236B2 (ja) 2011-01-27 2015-12-24 小野薬品工業株式会社 二環式化合物およびその医薬用途
WO2018003945A1 (ja) 2016-06-30 2018-01-04 小野薬品工業株式会社 二環式化合物の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
IT1079025B (it) * 1976-05-11 1985-05-08 Wellcome Found Perfezionamento nella preparazione di eteri
GB1583961A (en) * 1976-05-11 1981-02-04 Wellcome Found Prostacyclin and derivatives thereof
MX4813E (es) * 1976-06-01 1982-10-19 Upjohn Co Procedimiento para preparar analogos de prostaglandinas
US4125712A (en) * 1976-06-01 1978-11-14 The Upjohn Company Certain 5,6-dihydro-prostacyclin analogs
US4123441A (en) * 1976-09-22 1978-10-31 The Upjohn Company Enlarged-hetero-ring prostacyclin analogs
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
AU511711B2 (en) * 1976-12-30 1980-09-04 Upjohn Company, The 6-Oxo and 5, 6-Dihalo prostaglandin analogues
HU182583B (en) 1977-03-01 1984-02-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing prostacyclin and analogues thereof
AU524786B2 (en) * 1977-03-07 1982-10-07 The Upjohn Company Prostacyclins
GB2002363B (en) * 1977-08-03 1982-03-24 Upjohn Co Prostacyclin analogues
US4206127A (en) * 1977-11-23 1980-06-03 Miles Laboratories, Inc. 5,6-Dihydro analogues of prostaglandin I2

Also Published As

Publication number Publication date
HU182725B (en) 1984-03-28
KE3196A (en) 1982-04-02
IL53630A0 (en) 1978-03-10
FR2376147B1 (it) 1982-01-08
US4277491A (en) 1981-07-07
NO774524L (no) 1978-07-03
DE2757919A1 (de) 1978-07-13
GR66057B (it) 1981-01-14
NZ185986A (en) 1979-12-11
CH636096A5 (de) 1983-05-13
GB1599280A (en) 1981-09-30
NO153689B (no) 1986-01-27
FI773757A (fi) 1978-07-01
BE862514A (fr) 1978-04-14
MY8200265A (en) 1982-12-31
NL7714613A (nl) 1978-07-04
DK586077A (da) 1978-07-01
US4250188A (en) 1981-02-10
YU316677A (en) 1984-02-29
SE7714948L (sv) 1978-07-01
FI71138B (fi) 1986-08-14
US4271184A (en) 1981-06-02
US4230721A (en) 1980-10-28
FI71138C (fi) 1986-11-24
US4328240A (en) 1982-05-04
US4262016A (en) 1981-04-14
FR2376147A1 (fr) 1978-07-28
JPS5384959A (en) 1978-07-26
SE437268B (sv) 1985-02-18
US4254137A (en) 1981-03-03
US4303670A (en) 1981-12-01
US4297368A (en) 1981-10-27

Similar Documents

Publication Publication Date Title
NO153689C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive bicykliske prostaglandiner.
NO158540C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2-penem-forbindelser.
NO145199C (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive nortropinestere.
NO163691C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive n-acryl-piperazinalkanamider.
NO149586C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive polypeptider
NO160368C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive bicykliske azoforbindelser.
NO149662C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive c-076-forbindelser
NO152841C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive nye 4-aroylimidazol-2-oner.
NO145379C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive n2-arylsulfonyl-l-argininamider.
NO147953C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive antracyklinglukosider
NO151040C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-halogenpyrimid-2-oner
NO147109C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive diazepin-derivater
NO145762C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive antracyklinglykosidiske forbindelser
NO147150C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperidiner.
NO145163C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive antitumorglykosider
NO145620C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive depotsteroidestere.
NO151008C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive nitroforbindelser
NO146777C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 6h-indolo (3,2,1-de)-(1,5)-naftyridinderivater
NO159798C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive cefalosporin-oksyder.
NO147341C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2,9-dioxatricyclo-(4.3.1.03,7)-decaner
NO154088C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive tetrahydrokinoliner.
NO157934C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive antracyklinglykosider.
NO148924C (no) Analogifremgangsmaate ved fremstilling av immunpotensierende peptider.
NO153730C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktivt 10-brom-e-homo-eburnan.
NO153221C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 6-metoksy-alfa-karboksypenicilliner.