NO137694C - Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner

Info

Publication number
NO137694C
NO137694C NO2518/73A NO251873A NO137694C NO 137694 C NO137694 C NO 137694C NO 2518/73 A NO2518/73 A NO 2518/73A NO 251873 A NO251873 A NO 251873A NO 137694 C NO137694 C NO 137694C
Authority
NO
Norway
Prior art keywords
benzomorphans
preparation
therapeutically active
analogical procedure
analogical
Prior art date
Application number
NO2518/73A
Other languages
English (en)
Norwegian (no)
Other versions
NO137694B (no
Inventor
Herbert Merz
Adolf Langbein
Klaus Stockhaus
Helmut Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NO137694B publication Critical patent/NO137694B/no
Publication of NO137694C publication Critical patent/NO137694C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Steroid Compounds (AREA)
NO2518/73A 1972-06-19 1973-06-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner NO137694C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2229695A DE2229695A1 (de) 1972-06-19 1972-06-19 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
NO137694B NO137694B (no) 1977-12-27
NO137694C true NO137694C (no) 1978-04-05

Family

ID=5848060

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2518/73A NO137694C (no) 1972-06-19 1973-06-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner

Country Status (13)

Country Link
US (1) US3931194A (de)
JP (1) JPS5711908B2 (de)
AT (6) AT328627B (de)
BE (1) BE801079A (de)
CH (9) CH583228A5 (de)
DE (1) DE2229695A1 (de)
DK (1) DK136904C (de)
ES (8) ES416037A1 (de)
FR (1) FR2189056B1 (de)
GB (1) GB1433817A (de)
NL (1) NL7308483A (de)
NO (1) NO137694C (de)
SE (1) SE405121B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
JPS63177704A (ja) * 1987-01-16 1988-07-21 松山株式会社 農作業機連結装置
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) * 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (de) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclische harnstoffe als inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
ATE531696T1 (de) * 2008-02-12 2011-11-15 Boehringer Ingelheim Int Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
WO2009102460A2 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2291370B1 (de) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
WO2009134400A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
EP2288596B1 (de) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Alizyklische carboxylsäurederivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung
CA2730499A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1281227A (fr) * 1958-09-22 1962-01-12 Smith Kline French Lab Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane
BE582575A (de) * 1958-09-22
CS166804B2 (de) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
SE392895B (sv) * 1971-08-24 1977-04-25 Sumitomo Chemical Co Forfarande for framstellning av bensomorfanderivat och deras salter

Also Published As

Publication number Publication date
AT329199B (de) 1976-04-26
CH582698A5 (de) 1976-12-15
CH583231A5 (de) 1976-12-31
ES431516A1 (es) 1976-11-16
AU5704673A (en) 1974-12-19
ES431515A1 (es) 1976-11-01
BE801079A (fr) 1973-12-18
NO137694B (no) 1977-12-27
AT329200B (de) 1976-04-26
ES431511A1 (es) 1976-11-01
ES431512A1 (es) 1976-11-01
CH583229A5 (de) 1976-12-31
ES431510A1 (es) 1976-11-01
CH582697A5 (de) 1976-12-15
AT328628B (de) 1976-03-25
CH583227A5 (de) 1976-12-31
SE405121B (sv) 1978-11-20
CH583228A5 (de) 1976-12-31
ATA489774A (de) 1975-06-15
DE2229695A1 (de) 1974-01-31
US3931194A (en) 1976-01-06
AT325218B (de) 1975-10-10
DK136904B (da) 1977-12-12
GB1433817A (en) 1976-04-28
JPS4961170A (de) 1974-06-13
ATA489874A (de) 1975-07-15
ES431513A1 (es) 1976-11-01
FR2189056B1 (de) 1976-10-22
ATA490074A (de) 1975-06-15
DK136904C (da) 1978-06-26
NL7308483A (de) 1973-12-21
FR2189056A1 (de) 1974-01-25
AT328627B (de) 1976-03-25
ES431514A1 (es) 1976-11-01
JPS5711908B2 (de) 1982-03-08
ES416037A1 (es) 1976-02-16
ATA489974A (de) 1975-07-15
CH589648A5 (de) 1977-07-15
AT328629B (de) 1976-03-25
CH589649A5 (de) 1977-07-15
ATA489474A (de) 1975-06-15
CH583230A5 (de) 1976-12-31

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