NL192205B - Process for preparing 7-amino-3- (Z-1-propenyl) -3-cephem-4-carboxylic acid and esters thereof. - Google Patents

Process for preparing 7-amino-3- (Z-1-propenyl) -3-cephem-4-carboxylic acid and esters thereof.

Info

Publication number
NL192205B
NL192205B NL8601011A NL8601011A NL192205B NL 192205 B NL192205 B NL 192205B NL 8601011 A NL8601011 A NL 8601011A NL 8601011 A NL8601011 A NL 8601011A NL 192205 B NL192205 B NL 192205B
Authority
NL
Netherlands
Prior art keywords
cephem
propenyl
esters
amino
preparing
Prior art date
Application number
NL8601011A
Other languages
Dutch (nl)
Other versions
NL8601011A (en
NL192205C (en
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NL8601011A publication Critical patent/NL8601011A/en
Publication of NL192205B publication Critical patent/NL192205B/en
Application granted granted Critical
Publication of NL192205C publication Critical patent/NL192205C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
NL8601011A 1985-04-22 1986-04-21 Process for preparing 7-amino-3- (Z-1-propenyl) -3-cephem-4-carboxylic acid and esters thereof. NL192205C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72587185A 1985-04-22 1985-04-22
US72587185 1985-04-22

Publications (3)

Publication Number Publication Date
NL8601011A NL8601011A (en) 1986-11-17
NL192205B true NL192205B (en) 1996-11-01
NL192205C NL192205C (en) 1997-03-04

Family

ID=24916301

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8601011A NL192205C (en) 1985-04-22 1986-04-21 Process for preparing 7-amino-3- (Z-1-propenyl) -3-cephem-4-carboxylic acid and esters thereof.

Country Status (38)

Country Link
JP (1) JPS61249989A (en)
KR (1) KR860008189A (en)
CN (1) CN1015714B (en)
AR (1) AR242581A1 (en)
AT (1) AT392072B (en)
AU (1) AU589170B2 (en)
BE (1) BE904646A (en)
CA (1) CA1273629A (en)
CH (1) CH671399A5 (en)
CS (1) CS270435B2 (en)
CY (1) CY1571A (en)
DD (1) DD244557A5 (en)
DE (1) DE3613365A1 (en)
DK (1) DK163584C (en)
EG (1) EG18001A (en)
ES (1) ES8800236A1 (en)
FI (1) FI84268C (en)
FR (1) FR2580652B1 (en)
GB (1) GB2173798B (en)
GR (1) GR861065B (en)
HK (1) HK106290A (en)
HU (1) HU195223B (en)
IE (1) IE59014B1 (en)
IT (1) IT1228241B (en)
LU (1) LU86402A1 (en)
MY (1) MY100694A (en)
NL (1) NL192205C (en)
NO (1) NO164659C (en)
NZ (1) NZ215717A (en)
OA (1) OA08245A (en)
PT (1) PT82436B (en)
SE (1) SE500217C2 (en)
SG (1) SG90890G (en)
SU (1) SU1435155A3 (en)
YU (1) YU43697B (en)
ZA (1) ZA862985B (en)
ZM (1) ZM4286A1 (en)
ZW (1) ZW9086A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
US4870168A (en) * 1987-02-26 1989-09-26 Bristol-Myers Company 3-Unsaturated alkyl cephems from 3-triflyl cephems
DE3933934A1 (en) * 1989-10-03 1991-04-11 Bayer Ag METHOD FOR PRODUCING 7-AMINO-3 - ((Z) -1-PROPEN-1-YL) -3-CEPHEM-4-CARBONIC ACID
DE69231815T2 (en) * 1991-03-08 2001-09-27 Biochemie Gmbh Process for the preparation of cephalosporins and intermediates in this process
AT399876B (en) * 1992-02-05 1995-08-25 Biochemie Gmbh Purificn. of 7-amino-3-((z)-1-propen-1-yl)-3 -cephem-4-carboxylic acid - useful in prodn. of broadband antibiotics
KR950700311A (en) * 1992-02-05 1995-01-16 게오르게스 그렐리니, 한스 루돌프하우스 Process for the purification of a 3-cephem-4-carboxylic acid derivatives
JPH07173168A (en) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd Cephem compound, its production and utilization of the compound for production of cephem antibiotic substance
AU2003267733A1 (en) * 2002-10-08 2004-05-04 Ranbaxy Laboratories Limited Process for the preparation of (z)-isomer enriched 7-amino-3-propen-1-yl-3-cephem-4- carboxylic acid
EP1678186A4 (en) * 2003-10-30 2007-04-25 Cj Corp Processes for the preparation of cephem derivatives
JP4046708B2 (en) * 2004-06-04 2008-02-13 明治製菓株式会社 Method for producing 3-alkenylcephem compound
US20080281093A1 (en) 2004-11-01 2008-11-13 Bandi Parthasaradhi Reddy Novel Process For Preparation of Cefprozil Intermediate
CN103183686B (en) * 2011-12-30 2016-06-29 浙江新和成股份有限公司 The preparation method of 7 beta-amino-7 α-methoxyl group-3-cephem compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4110534A (en) * 1970-01-23 1978-08-29 Glaxo Laboratories Limited Process for the preparation of 3-vinyl and substituted vinyl cephalosporins
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4065620A (en) * 1971-06-14 1977-12-27 Eli Lilly And Company 3-(Substituted) vinyl cephalosporins
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
AU566944B2 (en) * 1983-10-07 1987-11-05 Gist-Brocades N.V. Preparation of 3-cephem derivatives

Also Published As

Publication number Publication date
AU589170B2 (en) 1989-10-05
FI84268B (en) 1991-07-31
FI861634A0 (en) 1986-04-17
NL8601011A (en) 1986-11-17
CY1571A (en) 1991-12-20
CH671399A5 (en) 1989-08-31
FR2580652A1 (en) 1986-10-24
JPH0327554B2 (en) 1991-04-16
DK182486A (en) 1986-10-23
CA1273629A (en) 1990-09-04
CN86102630A (en) 1987-02-04
PT82436A (en) 1986-05-01
CN1015714B (en) 1992-03-04
MY100694A (en) 1991-01-17
BE904646A (en) 1986-10-21
ES554215A0 (en) 1987-10-16
ATA106786A (en) 1990-07-15
GB2173798B (en) 1988-11-30
GR861065B (en) 1986-09-01
CS287286A2 (en) 1989-11-14
AU5616886A (en) 1986-11-06
IT1228241B (en) 1991-06-05
YU43697B (en) 1989-10-31
DK182486D0 (en) 1986-04-21
IE59014B1 (en) 1993-12-15
FI861634A (en) 1986-10-23
ZW9086A1 (en) 1986-12-03
SE8601825L (en) 1986-10-23
IT8620162A0 (en) 1986-04-21
ZM4286A1 (en) 1989-03-27
DE3613365A1 (en) 1987-01-02
NO164659C (en) 1990-10-31
DK163584B (en) 1992-03-16
ES8800236A1 (en) 1987-10-16
HU195223B (en) 1988-04-28
GB2173798A (en) 1986-10-22
SE500217C2 (en) 1994-05-09
AT392072B (en) 1991-01-25
NO861430L (en) 1986-10-23
SG90890G (en) 1991-01-18
AR242581A1 (en) 1993-04-30
DD244557A5 (en) 1987-04-08
IE861048L (en) 1986-10-22
KR860008189A (en) 1986-11-12
PT82436B (en) 1988-11-30
DK163584C (en) 1992-08-10
NL192205C (en) 1997-03-04
FR2580652B1 (en) 1989-01-06
SE8601825D0 (en) 1986-04-21
EG18001A (en) 1991-11-30
HK106290A (en) 1990-12-28
NZ215717A (en) 1989-06-28
ZA862985B (en) 1986-12-30
OA08245A (en) 1987-10-30
YU65986A (en) 1987-12-31
HUT41033A (en) 1987-03-30
SU1435155A3 (en) 1988-10-30
CS270435B2 (en) 1990-06-13
NO164659B (en) 1990-07-23
FI84268C (en) 1991-11-11
JPS61249989A (en) 1986-11-07
DE3613365C2 (en) 1989-06-15
LU86402A1 (en) 1986-11-05
GB8609661D0 (en) 1986-05-29

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BB A search report has been drawn up
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Free format text: BRISTOL-MYERS SQUIBB COMPANY

V4 Discontinued because of reaching the maximum lifetime of a patent

Effective date: 20060421