MY162518A - Proteasome inhibitors and methods of using the same - Google Patents
Proteasome inhibitors and methods of using the sameInfo
- Publication number
- MY162518A MY162518A MYPI20043299A MYPI20043299A MY162518A MY 162518 A MY162518 A MY 162518A MY PI20043299 A MYPI20043299 A MY PI20043299A MY PI20043299 A MYPI20043299 A MY PI20043299A MY 162518 A MY162518 A MY 162518A
- Authority
- MY
- Malaysia
- Prior art keywords
- methods
- same
- proteasome inhibitors
- compositions
- proteasome activity
- Prior art date
Links
Abstract
THE PRESENT INVENTION PROVIDES BORONIC ACID COMPOUNDS, BRONIC ESTERS, AND COMPOSITIONS THEREOF THAT CAN MODULATE APOPTOSIS SUCH AS BY INHIBITION OF PROTEASOME ACTIVITY. THE COMPOUNDS AND COMPOSITIONS CAN BE USED IN METHODS OF INDUCING APOPTOSIS AND TREATING DISEASES SUCH AS CANCER AND OTHER DISORDERS ASSOCIATED DIRECTLY OF INDIRECTLY WITH PROTEASOME ACTIVITY.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49576403P | 2003-08-14 | 2003-08-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MY162518A true MY162518A (en) | 2017-06-15 |
Family
ID=37426112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI20043299A MY162518A (en) | 2003-08-14 | 2004-08-13 | Proteasome inhibitors and methods of using the same |
Country Status (7)
Country | Link |
---|---|
CN (1) | CN1867572B (en) |
AR (2) | AR045381A1 (en) |
MY (1) | MY162518A (en) |
PE (1) | PE20050360A1 (en) |
TW (1) | TWI345465B (en) |
UA (1) | UA88771C2 (en) |
ZA (1) | ZA200601293B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102961387B (en) * | 2007-08-06 | 2016-04-27 | 米伦纽姆医药公司 | Proteasome inhibitor |
CN105837608B (en) * | 2007-08-06 | 2018-06-08 | 米伦纽姆医药公司 | Proteasome inhibitor and combinations thereof and purposes |
WO2009020448A1 (en) * | 2007-08-06 | 2009-02-12 | Millennium Pharmaceuticals, Inc. | Proteasome inhibitors |
MX349769B (en) * | 2008-06-17 | 2017-08-11 | Millennium Pharm Inc | Boronate ester compounds and pharmaceutical compositions thereof. |
CN101638414B (en) * | 2008-07-30 | 2014-01-08 | 江苏先声药物研究有限公司 | Peptidyl boronic acid, ester compound thereof, preparation method of peptidyl boronic acid and ester compound thereof, and use of peptidyl boronic acid and ester compound thereof |
AR075090A1 (en) * | 2008-09-29 | 2011-03-09 | Millennium Pharm Inc | ACID DERIVATIVES 1-AMINO-2-CYCLLOBUTILETILBORONICO PROTEOSOMA INHIBITORS, USEFUL AS ANTI-BANKER AGENTS, AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM. |
CN101747354B (en) * | 2008-12-04 | 2014-08-13 | 江苏先声药物研究有限公司 | Dipeptide boronic acids consisting of beta amino acids, ester compounds and preparation methods and uses thereof |
CN102725300B (en) * | 2009-12-22 | 2015-03-11 | 赛福伦公司 | Proteasome inhibitors and processes for their preparation, purification and use |
EA029521B1 (en) * | 2010-03-31 | 2018-04-30 | Милленниум Фармасьютикалз, Инк. | Derivatives of 1-amino-2-cyclopropylethylboronic acid |
KR102457840B1 (en) * | 2014-10-01 | 2022-10-21 | 메르크 파텐트 게엠베하 | Boronic acid derivatives |
CN106588965A (en) | 2015-10-15 | 2017-04-26 | 北京大学 | Urea peptidomimetic boric acid compound as well as pharmaceutical composition, preparation method and application thereof |
CN107400142B (en) * | 2016-05-19 | 2019-11-19 | 成都奥璟生物科技有限公司 | A kind of boric acid and boric acid ester compound and its application |
KR102534947B1 (en) * | 2017-01-18 | 2023-05-23 | 프린시피아 바이오파마, 인코퍼레이티드 | immunoproteasome inhibitors |
CN108440583B (en) * | 2017-01-23 | 2020-12-04 | 成都奥璟生物科技有限公司 | Boric acid derivative and its medicinal composition |
CN114437119A (en) * | 2020-10-30 | 2022-05-06 | 苏州开拓药业股份有限公司 | C-Myc protein inhibitor and preparation method and application thereof |
-
2004
- 2004-08-13 CN CN2004800301520A patent/CN1867572B/en active Active
- 2004-08-13 UA UAA200602694A patent/UA88771C2/en unknown
- 2004-08-13 MY MYPI20043299A patent/MY162518A/en unknown
- 2004-08-13 TW TW93124291A patent/TWI345465B/en active
- 2004-08-13 PE PE2004000784A patent/PE20050360A1/en active IP Right Grant
- 2004-08-17 AR ARP040102935 patent/AR045381A1/en not_active Application Discontinuation
-
2006
- 2006-02-13 ZA ZA200601293A patent/ZA200601293B/en unknown
-
2014
- 2014-03-11 AR ARP140100859A patent/AR095249A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW200529810A (en) | 2005-09-16 |
ZA200601293B (en) | 2009-09-30 |
PE20050360A1 (en) | 2005-06-10 |
AR045381A1 (en) | 2005-10-26 |
UA88771C2 (en) | 2009-11-25 |
AR095249A2 (en) | 2015-09-30 |
CN1867572B (en) | 2012-03-28 |
CN1867572A (en) | 2006-11-22 |
TWI345465B (en) | 2011-07-21 |
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