MY162518A - Proteasome inhibitors and methods of using the same - Google Patents

Proteasome inhibitors and methods of using the same

Info

Publication number
MY162518A
MY162518A MYPI20043299A MYPI20043299A MY162518A MY 162518 A MY162518 A MY 162518A MY PI20043299 A MYPI20043299 A MY PI20043299A MY PI20043299 A MYPI20043299 A MY PI20043299A MY 162518 A MY162518 A MY 162518A
Authority
MY
Malaysia
Prior art keywords
methods
same
proteasome inhibitors
compositions
proteasome activity
Prior art date
Application number
MYPI20043299A
Inventor
Bernareggi Alberto
Bernardini Raffaella
De Munari Sergio
G Cassara Paolo
Chatterjee Sankar
Ferretti Edmondo
Iqbal Mohamed
A Messina Mclaughlin Patricia
Menta Ernesto
Oliva Ambrogio
D' Arasmo Germano
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MY162518A publication Critical patent/MY162518A/en

Links

Abstract

THE PRESENT INVENTION PROVIDES BORONIC ACID COMPOUNDS, BRONIC ESTERS, AND COMPOSITIONS THEREOF THAT CAN MODULATE APOPTOSIS SUCH AS BY INHIBITION OF PROTEASOME ACTIVITY. THE COMPOUNDS AND COMPOSITIONS CAN BE USED IN METHODS OF INDUCING APOPTOSIS AND TREATING DISEASES SUCH AS CANCER AND OTHER DISORDERS ASSOCIATED DIRECTLY OF INDIRECTLY WITH PROTEASOME ACTIVITY.
MYPI20043299A 2003-08-14 2004-08-13 Proteasome inhibitors and methods of using the same MY162518A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49576403P 2003-08-14 2003-08-14

Publications (1)

Publication Number Publication Date
MY162518A true MY162518A (en) 2017-06-15

Family

ID=37426112

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20043299A MY162518A (en) 2003-08-14 2004-08-13 Proteasome inhibitors and methods of using the same

Country Status (7)

Country Link
CN (1) CN1867572B (en)
AR (2) AR045381A1 (en)
MY (1) MY162518A (en)
PE (1) PE20050360A1 (en)
TW (1) TWI345465B (en)
UA (1) UA88771C2 (en)
ZA (1) ZA200601293B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102961387B (en) * 2007-08-06 2016-04-27 米伦纽姆医药公司 Proteasome inhibitor
CN105837608B (en) * 2007-08-06 2018-06-08 米伦纽姆医药公司 Proteasome inhibitor and combinations thereof and purposes
WO2009020448A1 (en) * 2007-08-06 2009-02-12 Millennium Pharmaceuticals, Inc. Proteasome inhibitors
MX349769B (en) * 2008-06-17 2017-08-11 Millennium Pharm Inc Boronate ester compounds and pharmaceutical compositions thereof.
CN101638414B (en) * 2008-07-30 2014-01-08 江苏先声药物研究有限公司 Peptidyl boronic acid, ester compound thereof, preparation method of peptidyl boronic acid and ester compound thereof, and use of peptidyl boronic acid and ester compound thereof
AR075090A1 (en) * 2008-09-29 2011-03-09 Millennium Pharm Inc ACID DERIVATIVES 1-AMINO-2-CYCLLOBUTILETILBORONICO PROTEOSOMA INHIBITORS, USEFUL AS ANTI-BANKER AGENTS, AND PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM.
CN101747354B (en) * 2008-12-04 2014-08-13 江苏先声药物研究有限公司 Dipeptide boronic acids consisting of beta amino acids, ester compounds and preparation methods and uses thereof
CN102725300B (en) * 2009-12-22 2015-03-11 赛福伦公司 Proteasome inhibitors and processes for their preparation, purification and use
EA029521B1 (en) * 2010-03-31 2018-04-30 Милленниум Фармасьютикалз, Инк. Derivatives of 1-amino-2-cyclopropylethylboronic acid
KR102457840B1 (en) * 2014-10-01 2022-10-21 메르크 파텐트 게엠베하 Boronic acid derivatives
CN106588965A (en) 2015-10-15 2017-04-26 北京大学 Urea peptidomimetic boric acid compound as well as pharmaceutical composition, preparation method and application thereof
CN107400142B (en) * 2016-05-19 2019-11-19 成都奥璟生物科技有限公司 A kind of boric acid and boric acid ester compound and its application
KR102534947B1 (en) * 2017-01-18 2023-05-23 프린시피아 바이오파마, 인코퍼레이티드 immunoproteasome inhibitors
CN108440583B (en) * 2017-01-23 2020-12-04 成都奥璟生物科技有限公司 Boric acid derivative and its medicinal composition
CN114437119A (en) * 2020-10-30 2022-05-06 苏州开拓药业股份有限公司 C-Myc protein inhibitor and preparation method and application thereof

Also Published As

Publication number Publication date
TW200529810A (en) 2005-09-16
ZA200601293B (en) 2009-09-30
PE20050360A1 (en) 2005-06-10
AR045381A1 (en) 2005-10-26
UA88771C2 (en) 2009-11-25
AR095249A2 (en) 2015-09-30
CN1867572B (en) 2012-03-28
CN1867572A (en) 2006-11-22
TWI345465B (en) 2011-07-21

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