MY115721A - Benzothiophene compounds, intermediates, compositionsm, and methods - Google Patents
Benzothiophene compounds, intermediates, compositionsm, and methodsInfo
- Publication number
- MY115721A MY115721A MYPI96000722A MYPI9600722A MY115721A MY 115721 A MY115721 A MY 115721A MY PI96000722 A MYPI96000722 A MY PI96000722A MY PI9600722 A MYPI9600722 A MY PI9600722A MY 115721 A MY115721 A MY 115721A
- Authority
- MY
- Malaysia
- Prior art keywords
- alkyl
- compositionsm
- intermediates
- methods
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
THE PRESENT INVENTION PROVIDES PHARMACEUTICALLY ACTIVE COMPOUNDS OF FORMULA I WHEREIN RL IS -H, -OH, -O(CL-C4 ALKYL), -OCOC6H5, -OCO(CL-C6 ALKYL), OR -OSO2(C2-C6 ALKYL); R2 IS -H, -OH, -O(CL-C4 ALKYL), -OCOC6H5, -OCO(CL-C6 ALKYL), -OSO2(C2-C6 ALKYL), OR HALO; R3 IS 1-PIPERIDINYL, 1-PYR~OLIDINYL, METHYL-1- PYRROLIDINYL, DIMETHYL-1-PYRROLIDINYL, 4-MORPHOLINO, DIMETHYLAMINO, DIETHYLAMINO, DIISOPROPYLAMINO, OR 1- HEX AM ETHYLENE IMINO; N IS 2 OR 3; AND Z IS -O- OR -S-; OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF.FURTHER PROVIDED ARE PHARMACEUTICAL COMPOSITIONS OF COMPOUNDS OF FORMULA I.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/396,401 US5510357A (en) | 1995-02-28 | 1995-02-28 | Benzothiophene compounds as anti-estrogenic agents |
US55276095A | 1995-11-03 | 1995-11-03 | |
US08/552,636 US5723474A (en) | 1995-02-28 | 1995-11-03 | Benzothiophene compounds, intermediates, compositions, and methods |
US08/552,564 US5998441A (en) | 1995-02-28 | 1995-11-03 | Benzothiophene compounds, intermediates, compositions, and methods |
US08/552,890 US5919800A (en) | 1995-02-28 | 1995-11-03 | Benzothiophene compounds, intermediates, compositions, and methods |
US08/552,565 US5977093A (en) | 1995-02-28 | 1995-11-03 | Benzothiophene compounds, intermediates, compositions, and methods |
US08/552,679 US5856339A (en) | 1995-02-28 | 1995-11-03 | Benzothiophene compounds, intermediates, compositions, and methods |
US08/554,223 US5856340A (en) | 1995-02-28 | 1995-11-03 | Method of treating estrogen dependent cancers |
Publications (1)
Publication Number | Publication Date |
---|---|
MY115721A true MY115721A (en) | 2003-08-30 |
Family
ID=27569747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MYPI96000722A MY115721A (en) | 1995-02-28 | 1996-02-28 | Benzothiophene compounds, intermediates, compositionsm, and methods |
Country Status (4)
Country | Link |
---|---|
KR (1) | KR100446895B1 (en) |
MY (1) | MY115721A (en) |
NZ (1) | NZ286079A (en) |
RS (1) | RS49886B (en) |
-
1996
- 1996-02-27 RS YUP-118/96A patent/RS49886B/en unknown
- 1996-02-27 NZ NZ286079A patent/NZ286079A/en not_active IP Right Cessation
- 1996-02-27 KR KR1019960004749A patent/KR100446895B1/en not_active IP Right Cessation
- 1996-02-28 MY MYPI96000722A patent/MY115721A/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR960031454A (en) | 1996-09-17 |
KR100446895B1 (en) | 2006-04-10 |
RS49886B (en) | 2008-08-07 |
NZ286079A (en) | 1997-12-19 |
YU11896A (en) | 1998-12-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9600743A (en) | Compounds, intermediates, compositions, and methods. | |
GEP20084496B (en) | Benzothiophene compound, intermediate, composition, and method | |
YU61595A (en) | New naphthyl compounds, intermediates, processes, compositions and methods for the preparation thereof | |
AR003930A1 (en) | PROCEDURE FOR PREPARING COMPOUNDS OF 2-PHENYL-3-PHENOXY OR PHENYLTIO-BENZOTIOFEN AND PHARMACEUTICALLY ACCEPTABLE SALTS, INTERMEDIATE COMPOUNDS OF EXCLUSIVE APPLICATION IN SUCH PROCEDURE AND METHOD FOR PREPARING INTERMEDIATE COMPOUNDS | |
NZ326132A (en) | Retroviral protease inhibiting compounds | |
HUP0302937A2 (en) | Hmg-coa reductase inhibitors and their use and pharmaceutical compositions containing them | |
AU6724796A (en) | Non-steroidal sulfatase inhibitor compounds and their method of use | |
MX9605156A (en) | Peptidylaldehyde derivative and use thereof. | |
CA2149496A1 (en) | 11,21-bisphenyl-19-norpregnane derivatives | |
AU7517400A (en) | N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent | |
MX9800718A (en) | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives. | |
GB9211172D0 (en) | Compounds | |
MX9800800A (en) | Naphthyl and dihydronaphthyl intermediates, compounds, compositions, and methods. | |
NZ308518A (en) | Antibacterial cephalosporins | |
TW372969B (en) | Pharmaceutical composition for minimizing bone loss | |
MY115721A (en) | Benzothiophene compounds, intermediates, compositionsm, and methods | |
GR3032492T3 (en) | Interleukin-1 inhibitor | |
CA2170479A1 (en) | Benzothiophene compounds, intermediates, compositions, and methods | |
PT832881E (en) | BENZOFLUORENO COMPOUNDS INTERMEDIARY COMPOSITIONS AND METHODS | |
MY113757A (en) | Methods of inhibiting endometrial cancer | |
GB2333293B (en) | Process for the preparation of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide used as anti cancer compounds | |
TW349096B (en) | Benzothiophene compounds, intermediates, compositions, and methods |