TW349096B - Benzothiophene compounds, intermediates, compositions, and methods - Google Patents

Benzothiophene compounds, intermediates, compositions, and methods

Info

Publication number
TW349096B
TW349096B TW085102240A TW85102240A TW349096B TW 349096 B TW349096 B TW 349096B TW 085102240 A TW085102240 A TW 085102240A TW 85102240 A TW85102240 A TW 85102240A TW 349096 B TW349096 B TW 349096B
Authority
TW
Taiwan
Prior art keywords
alkyl
intermediates
compositions
methods
benzothiophene compounds
Prior art date
Application number
TW085102240A
Other languages
Chinese (zh)
Inventor
Alan David Palkowitz
Kenneth Jeff Thrasher
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/396,401 external-priority patent/US5510357A/en
Priority claimed from US08/554,223 external-priority patent/US5856340A/en
Priority claimed from US08/552,679 external-priority patent/US5856339A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of TW349096B publication Critical patent/TW349096B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of the formula I (I) in which R1 is -H, -OH, -O(C1-C4-alkyl), -OCOC6H5, or -OSO2(C2-C6-alkyl); R2 is -H, -OH, -O(C1-C4-alkyl), -OCOC6H5, -OCO(C1-C6-alkyl), -OSO2(C2-C6-alkyl) or halogen; R3 is 1-peperidinyl, 1-pyrrolidinyl, 4-morpholino, dimethylamino, diethylamino, diisopropylamino, or 1-hexamethyleneimino; n is 2 or 3; andZ is -O- or -S-; or a pharmaceutically acceptable salt thereof.
TW085102240A 1995-02-28 1996-02-27 Benzothiophene compounds, intermediates, compositions, and methods TW349096B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/396,401 US5510357A (en) 1995-02-28 1995-02-28 Benzothiophene compounds as anti-estrogenic agents
US08/554,223 US5856340A (en) 1995-02-28 1995-11-03 Method of treating estrogen dependent cancers
US08/552,679 US5856339A (en) 1995-02-28 1995-11-03 Benzothiophene compounds, intermediates, compositions, and methods
US08/552,636 US5723474A (en) 1995-02-28 1995-11-03 Benzothiophene compounds, intermediates, compositions, and methods

Publications (1)

Publication Number Publication Date
TW349096B true TW349096B (en) 1999-01-01

Family

ID=57939794

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085102240A TW349096B (en) 1995-02-28 1996-02-27 Benzothiophene compounds, intermediates, compositions, and methods

Country Status (1)

Country Link
TW (1) TW349096B (en)

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Legal Events

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MM4A Annulment or lapse of patent due to non-payment of fees