MXPA06014187A - Procedimiento para carbonilar derivados de fenilalquilo por medio de monoxido de carbono. - Google Patents
Procedimiento para carbonilar derivados de fenilalquilo por medio de monoxido de carbono.Info
- Publication number
- MXPA06014187A MXPA06014187A MXPA06014187A MXPA06014187A MXPA06014187A MX PA06014187 A MXPA06014187 A MX PA06014187A MX PA06014187 A MXPA06014187 A MX PA06014187A MX PA06014187 A MXPA06014187 A MX PA06014187A MX PA06014187 A MXPA06014187 A MX PA06014187A
- Authority
- MX
- Mexico
- Prior art keywords
- carbon monoxide
- carbonylating
- formula
- alkyl
- phenylalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/10—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide
- C07C51/12—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction with carbon monoxide on an oxygen-containing group in organic compounds, e.g. alcohols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/687—Unsaturated compounds containing a keto groups being part of a ring containing halogen
- C07C49/697—Unsaturated compounds containing a keto groups being part of a ring containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
La invencion se refiere a un metodo para preparar derivados de acido fenilalquilcarboxilico de la formula general (1) (1) R3 en la que Rl y R2, iguales o diferentes, representan cada uno independientemente alquilo(C1-C4), Z es un atomo de hidrogeno o -(CH2)- CH3 en el que n desde O a 9 y R3 es -C(O)-alquil(C1-C4) en el que el alquilo esta sin sustituir o monosustituido por CI o Br, o -C(O)-cicloalquil(C3-C6), en el que el compuesto de la formula (II) Rl R4 (II) en la que X es CI, Br o -OH y R4 es como se define para el radical R2 o, junto con X, en un doble enlace C=C se hace reaccionar con monoxido de carbono en presencia de acido sulfurico concentrado, fluoruro de hidrogeno o de superacidos, y posteriormente se anade agua o un alcohol de la formula CH3- (CH2)-OH en la que n = desde O a 9.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004031849A DE102004031849A1 (de) | 2004-06-30 | 2004-06-30 | Verfahren zur Carbonylierung von Phenylalkylderivaten mit Kohlenmonoxid |
PCT/EP2005/006414 WO2006002762A2 (de) | 2004-06-30 | 2005-06-15 | Verfahren zur carbonylierung von phenylalkylderivaten mit kohlenmonoxid |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA06014187A true MXPA06014187A (es) | 2007-05-23 |
Family
ID=35219528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA06014187A MXPA06014187A (es) | 2004-06-30 | 2005-06-15 | Procedimiento para carbonilar derivados de fenilalquilo por medio de monoxido de carbono. |
Country Status (23)
Country | Link |
---|---|
US (2) | US20070161814A1 (es) |
EP (1) | EP1776330B1 (es) |
JP (1) | JP4934028B2 (es) |
KR (1) | KR101228860B1 (es) |
CN (2) | CN101570476B (es) |
AR (1) | AR049948A1 (es) |
AT (1) | ATE479648T1 (es) |
AU (1) | AU2005259632B2 (es) |
BR (1) | BRPI0512650A (es) |
CA (1) | CA2572124C (es) |
CY (1) | CY1110955T1 (es) |
DE (2) | DE102004031849A1 (es) |
DK (1) | DK1776330T3 (es) |
ES (1) | ES2348666T3 (es) |
HK (1) | HK1101071A1 (es) |
IL (1) | IL180330A (es) |
MX (1) | MXPA06014187A (es) |
PL (1) | PL1776330T3 (es) |
PT (1) | PT1776330E (es) |
SI (1) | SI1776330T1 (es) |
TW (1) | TW200621699A (es) |
UY (1) | UY28992A1 (es) |
WO (1) | WO2006002762A2 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2968658B1 (fr) | 2010-12-13 | 2013-04-26 | Aet Group | Procede continu de carbonylation d'alcools, et notamment de phenylalcools |
CN104557671B (zh) * | 2013-10-10 | 2018-04-13 | 池州东升药业有限公司 | 一种非索非那定及中间体的合成方法 |
JP6466477B2 (ja) | 2014-06-10 | 2019-02-06 | アイジーエム レシンス イタリア ソチエタ レスポンサビリタ リミタータ | フェニルインダン光開始剤の製法 |
CN109704941A (zh) * | 2019-01-24 | 2019-05-03 | 淄博润源化工有限公司 | 3,4-二甲基苯甲醛的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2634294A (en) * | 1950-04-08 | 1953-04-07 | Monsanto Chemicals | Preparation of aromatic keto alcohols |
DE69431954T2 (de) * | 1993-06-25 | 2003-11-06 | Merrell Pharmaceuticals Inc., Cincinnati | Neue zwischenprodukte für die herstellung von antihistaminschen 4-diphenylmethyl/diphenylmethoxypiperidin-derivaten |
US6531597B2 (en) * | 2001-02-13 | 2003-03-11 | Hoffmann-La Roche Inc. | Process for preparation of 2-phenyl acetic acid derivatives |
JP2004521942A (ja) | 2001-06-25 | 2004-07-22 | オーロビンド ファーマ リミテッド | 高純度医薬中間体である4−(シクロプロピルカルボニル)−α,α−ジメチルフェニル酢酸の製造方法 |
-
2004
- 2004-06-30 DE DE102004031849A patent/DE102004031849A1/de not_active Withdrawn
-
2005
- 2005-06-15 CN CN2009102035964A patent/CN101570476B/zh not_active Expired - Fee Related
- 2005-06-15 DK DK05760701.2T patent/DK1776330T3/da active
- 2005-06-15 WO PCT/EP2005/006414 patent/WO2006002762A2/de not_active Application Discontinuation
- 2005-06-15 BR BRPI0512650-9A patent/BRPI0512650A/pt not_active Application Discontinuation
- 2005-06-15 MX MXPA06014187A patent/MXPA06014187A/es active IP Right Grant
- 2005-06-15 PL PL05760701T patent/PL1776330T3/pl unknown
- 2005-06-15 JP JP2007518483A patent/JP4934028B2/ja not_active Expired - Fee Related
- 2005-06-15 CA CA2572124A patent/CA2572124C/en not_active Expired - Fee Related
- 2005-06-15 PT PT05760701T patent/PT1776330E/pt unknown
- 2005-06-15 CN CN2005800220180A patent/CN1976888B/zh not_active Expired - Fee Related
- 2005-06-15 KR KR1020067027663A patent/KR101228860B1/ko not_active IP Right Cessation
- 2005-06-15 AT AT05760701T patent/ATE479648T1/de active
- 2005-06-15 SI SI200531170T patent/SI1776330T1/sl unknown
- 2005-06-15 ES ES05760701T patent/ES2348666T3/es active Active
- 2005-06-15 EP EP05760701A patent/EP1776330B1/de not_active Not-in-force
- 2005-06-15 DE DE502005010183T patent/DE502005010183D1/de active Active
- 2005-06-15 AU AU2005259632A patent/AU2005259632B2/en not_active Ceased
- 2005-06-28 TW TW094121517A patent/TW200621699A/zh unknown
- 2005-06-28 AR ARP050102661A patent/AR049948A1/es unknown
- 2005-06-30 UY UY28992A patent/UY28992A1/es unknown
-
2006
- 2006-12-19 US US11/612,971 patent/US20070161814A1/en not_active Abandoned
- 2006-12-26 IL IL180330A patent/IL180330A/en not_active IP Right Cessation
-
2007
- 2007-08-13 HK HK07108733.8A patent/HK1101071A1/xx not_active IP Right Cessation
-
2009
- 2009-07-24 US US12/508,798 patent/US8269033B2/en not_active Expired - Fee Related
-
2010
- 2010-11-25 CY CY20101101078T patent/CY1110955T1/el unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant or registration |