MXPA03009576A - Nuevos compuestos de imidazolina, un proceso para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Nuevos compuestos de imidazolina, un proceso para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
MXPA03009576A
MXPA03009576A MXPA03009576A MXPA03009576A MXPA03009576A MX PA03009576 A MXPA03009576 A MX PA03009576A MX PA03009576 A MXPA03009576 A MX PA03009576A MX PA03009576 A MXPA03009576 A MX PA03009576A MX PA03009576 A MXPA03009576 A MX PA03009576A
Authority
MX
Mexico
Prior art keywords
imidazoline
preparation
pharmaceutical compositions
compositions containing
novel derivatives
Prior art date
Application number
MXPA03009576A
Other languages
English (en)
Inventor
Rault Sylvain
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of MXPA03009576A publication Critical patent/MXPA03009576A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invencion describe compuestos de formula (I):(ver formula) en donde: ¦ R1 representa un grupo heteroarilo opcionalmente substituido, ¦ R2 representa un grupo cicloalquilo opcionalmente substituido, ¦R3 representa un atomo de hidrogeno o un grupo alquilo, y R4 y R5 son como se definieron en la descripcion, los enantiomeros, diastereoisomeros y tautomeros de los mismos, y tambien las sales de adicion de los mismos con un acido o base farmaceuticamente aceptable. Medicamentos.
MXPA03009576A 2002-10-23 2003-10-20 Nuevos compuestos de imidazolina, un proceso para su preparacion y composiciones farmaceuticas que los contienen. MXPA03009576A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0213194A FR2846328B1 (fr) 2002-10-23 2002-10-23 Nouveaux derives de l'imidazoline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
MXPA03009576A true MXPA03009576A (es) 2004-04-29

Family

ID=29763935

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA03009576A MXPA03009576A (es) 2002-10-23 2003-10-20 Nuevos compuestos de imidazolina, un proceso para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (25)

Country Link
US (2) US6875788B2 (es)
EP (1) EP1413579B1 (es)
JP (1) JP2004143167A (es)
KR (1) KR100642844B1 (es)
CN (1) CN1234694C (es)
AR (1) AR041688A1 (es)
AT (1) ATE288432T1 (es)
AU (1) AU2003257606A1 (es)
BR (1) BR0304634A (es)
CA (1) CA2445817A1 (es)
DE (1) DE60300307T2 (es)
DK (1) DK1413579T3 (es)
EA (1) EA006197B1 (es)
ES (1) ES2236672T3 (es)
FR (1) FR2846328B1 (es)
HK (1) HK1063320A1 (es)
MA (1) MA27013A1 (es)
MX (1) MXPA03009576A (es)
NO (1) NO20034722L (es)
NZ (1) NZ529084A (es)
PL (1) PL363022A1 (es)
PT (1) PT1413579E (es)
SG (2) SG127755A1 (es)
SI (1) SI1413579T1 (es)
ZA (1) ZA200308265B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115595135B (zh) * 2021-07-08 2023-09-01 中国石油化工股份有限公司 环烷基咪唑啉在用于抑制天然气水合物形成的应用及含有其的组合物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT295520B (de) * 1968-02-09 1972-01-10 Scherico Ltd Verfahren zur Herstellung neuer cyclischer Amidine und ihrer Salze
US3932431A (en) * 1970-06-24 1976-01-13 Schering Corporation Certain 2-[α(2-pyridyl)-benzyl] imidazolines and derivatives thereof
US4081544A (en) * 1975-12-04 1978-03-28 Schering Corporation Certain 2-(alpha(2-pyridyl)-benzyl)imidazolines and derivatives thereof
IE61028B1 (en) * 1987-10-19 1994-09-07 Beecham Group Plc Imidazole derivatives, process for their preparation and their use as alpha 2-adreno-receptor antagonists
GB8916150D0 (en) * 1989-07-14 1989-08-31 Beecham Group Plc Novel compounds
GB9123857D0 (en) * 1991-11-09 1992-01-02 Smithkline Beecham Plc Novel compounds
CA2085844A1 (en) * 1991-12-27 1993-06-28 Nobuyuki Hamanaka Fused benzeneoxyacetic acid derivatives
JP3416141B2 (ja) * 1994-02-04 2003-06-16 アイシー・ワン・インコーポレイテッド 奨励クレジットの割当て及び割戻し方法及び装置
CA2180891C (en) * 1995-07-12 2010-01-12 Junichi Rekimoto Notification of updates in a three-dimensional virtual reality space sharing system
US5937391A (en) * 1996-07-11 1999-08-10 Fujitsu Limited Point-service system in online shopping mall
US5926179A (en) * 1996-09-30 1999-07-20 Sony Corporation Three-dimensional virtual reality space display processing apparatus, a three-dimensional virtual reality space display processing method, and an information providing medium
US5866579A (en) * 1997-04-11 1999-02-02 Synaptic Pharmaceutical Corporation Imidazole and imidazoline derivatives and uses thereof
US20050203835A1 (en) * 1998-01-30 2005-09-15 Eli Nhaissi Internet billing
GB2351081A (en) * 1999-06-18 2000-12-20 Lilly Forschung Gmbh Pharmaceutically active imidazoline compounds and analogues thereof
US7037194B2 (en) * 2000-03-23 2006-05-02 Atlantic City Coin & Slot Service Company, Inc. Method and device for playing a game
US6672961B1 (en) * 2000-03-16 2004-01-06 Sony Computer Entertainment America Inc. Computer system and method of displaying images
US7383223B1 (en) * 2000-09-20 2008-06-03 Cashedge, Inc. Method and apparatus for managing multiple accounts
WO2003049742A1 (en) * 2001-12-11 2003-06-19 Boehringer Ingelheim Pharmaceuticals, Inc. Method for administering birb 796 bs
US20050235008A1 (en) * 2002-08-01 2005-10-20 Walt Camping Apparatus and method for collateral recovery
US20050177492A1 (en) * 2002-08-01 2005-08-11 Walt Camping Apparatus and method for asset tracking and recovery
US20050137904A1 (en) * 2003-10-14 2005-06-23 Kathleen Lane System and method for monitoring secured liens
US7882023B2 (en) * 2004-06-23 2011-02-01 Paul Parrish Method and system for managing collateral or property risk in a secured loan or lease portfolio
US7055740B1 (en) * 2004-12-06 2006-06-06 Target Brands, Inc. Stored-value card adapted to be read by an electronic device

Also Published As

Publication number Publication date
DE60300307T2 (de) 2006-01-19
CA2445817A1 (fr) 2004-04-23
EA006197B1 (ru) 2005-10-27
ATE288432T1 (de) 2005-02-15
EA200301045A3 (ru) 2004-08-26
JP2004143167A (ja) 2004-05-20
DE60300307D1 (de) 2005-03-10
SG127755A1 (en) 2006-12-29
FR2846328A1 (fr) 2004-04-30
US20050143440A1 (en) 2005-06-30
AR041688A1 (es) 2005-05-26
NZ529084A (en) 2005-04-29
KR20040036590A (ko) 2004-04-30
NO20034722L (no) 2004-04-26
AU2003257606A1 (en) 2004-05-13
KR100642844B1 (ko) 2006-11-10
PL363022A1 (en) 2004-05-04
ES2236672T3 (es) 2005-07-16
NO20034722D0 (no) 2003-10-22
BR0304634A (pt) 2004-06-01
SI1413579T1 (en) 2005-06-30
CN1496982A (zh) 2004-05-19
PT1413579E (pt) 2005-05-31
EP1413579A1 (fr) 2004-04-28
MA27013A1 (fr) 2004-12-20
US20040087638A1 (en) 2004-05-06
DK1413579T3 (da) 2005-05-09
EP1413579B1 (fr) 2005-02-02
EA200301045A2 (ru) 2004-04-29
ZA200308265B (en) 2004-07-09
SG113482A1 (en) 2005-08-29
HK1063320A1 (en) 2004-12-24
FR2846328B1 (fr) 2004-12-10
US6875788B2 (en) 2005-04-05
CN1234694C (zh) 2006-01-04

Similar Documents

Publication Publication Date Title
TNSN05160A1 (en) Novel fluoroglycoside heterocyclic derivatives, pharmaceutical products containing said compounds and the use thereof
NZ536734A (en) Spiroindolinepiperidine derivatives
RS20050394A (en) Novel aromatic fluoroglycoside derivatives, pharmaceutical products containing said compounds and the use thereof
MY138452A (en) Novel process for synthesizing and a novel crystal form of agomelatine as well as pharmaceutical preparations containing these
SE0104140D0 (sv) Novel Compounds
EP1775289A4 (en) NEW IMIDAZOLIDINE DERIVATIVES
TW200637869A (en) The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
MXPA05011597A (es) Derivados de aminopropanol como moduladores del receptor 1-fosfato de esfingosina.
UA83814C2 (ru) Производные фосфонооксихиназолина и их фармацевтическое применение
CA2425560A1 (en) Anticholinergics, processes for preparing them and their use as pharmaceutical compositions
NO20054329L (no) Adamantanderivater, fremgangsmater for deres fremstilling og farmasoytiske sammensetninger som innbefatter slike
DE602004008895D1 (en) Dpp-iv-hemmer
IL173810A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same
WO2004048340A8 (en) Sinomenine and sinomenine compounds, synthesis and use
TW200503998A (en) Phenyl compounds
IL176171A0 (en) N-aryl piperidine substituted biphenylcarboxamides
TW200702330A (en) 3,4,5-Substituted piperidines
MXPA05013348A (es) Derivados de amino-propanol como moduladores del receptor de esfingosina-1-fosfato.
TW200616636A (en) Novel compounds
TW200635917A (en) Novel compounds
TW200605888A (en) Novel compounds
JO2409B1 (en) Second-phenyl carboxy amides are useful as lipid-lowering agents
TW200740781A (en) Novel compounds
JO2390B1 (en) Diphenylcarboxamides act as lipid-lowering agents
IL173895A0 (en) Imidazopyridine derivatives and pharmaceutical compositions containing the same