MXPA03009209A - Formulaciones de 3,7-diazabiciclo-[3.3.1] como compuestos anti-arritmicos. - Google Patents
Formulaciones de 3,7-diazabiciclo-[3.3.1] como compuestos anti-arritmicos.Info
- Publication number
- MXPA03009209A MXPA03009209A MXPA03009209A MXPA03009209A MXPA03009209A MX PA03009209 A MXPA03009209 A MX PA03009209A MX PA03009209 A MXPA03009209 A MX PA03009209A MX PA03009209 A MXPA03009209 A MX PA03009209A MX PA03009209 A MXPA03009209 A MX PA03009209A
- Authority
- MX
- Mexico
- Prior art keywords
- arrythmic
- diazabicyclo
- formulations
- compounds
- arrythmic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0101329A SE0101329D0 (sv) | 2001-04-12 | 2001-04-12 | Pharmaceutical formulation |
PCT/SE2002/000726 WO2002083689A1 (en) | 2001-04-12 | 2002-04-12 | 3,7-diazabicyclo [3.3.1] formulations as anti-arrythmic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03009209A true MXPA03009209A (es) | 2004-01-29 |
Family
ID=20283785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03009209A MXPA03009209A (es) | 2001-04-12 | 2002-04-12 | Formulaciones de 3,7-diazabiciclo-[3.3.1] como compuestos anti-arritmicos. |
Country Status (26)
Country | Link |
---|---|
US (1) | US20050037067A1 (es) |
EP (1) | EP1389212B1 (es) |
JP (1) | JP2005500262A (es) |
KR (1) | KR20030088498A (es) |
CN (1) | CN1514839A (es) |
AR (1) | AR035806A1 (es) |
AT (1) | ATE332902T1 (es) |
BG (1) | BG108234A (es) |
BR (1) | BR0208828A (es) |
CA (1) | CA2443473A1 (es) |
CZ (1) | CZ20032774A3 (es) |
DE (1) | DE60213084T2 (es) |
EE (1) | EE200300495A (es) |
HU (1) | HUP0303486A3 (es) |
IL (1) | IL158033A0 (es) |
IS (1) | IS6989A (es) |
MX (1) | MXPA03009209A (es) |
NO (1) | NO20034529L (es) |
NZ (1) | NZ528561A (es) |
PL (1) | PL366629A1 (es) |
RU (1) | RU2003129230A (es) |
SE (1) | SE0101329D0 (es) |
SK (1) | SK12562003A3 (es) |
TW (1) | TWI257391B (es) |
WO (1) | WO2002083689A1 (es) |
ZA (1) | ZA200307756B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI259836B (en) * | 2001-04-12 | 2006-08-11 | Astrazeneca Ab | Modified release formulation suitable for antiarrhythmic compounds |
US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
GB0523810D0 (en) * | 2005-11-23 | 2006-01-04 | Astrazeneca Ab | Pharmaceutical compositions |
EA015682B1 (ru) * | 2005-12-20 | 2011-10-31 | Лек Фармасьютиклз Д.Д. | Фармацевтическая композиция |
US20080085303A1 (en) * | 2006-10-10 | 2008-04-10 | Penwest Pharmaceuticals Co. | Robust sustained release formulations of oxymorphone and methods of use thereof |
CA2644179C (en) * | 2007-11-21 | 2018-09-25 | Pharmascience Inc. | Novel pharmaceutical composition comprising a disintegration matrix |
DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
US9408835B2 (en) * | 2013-03-29 | 2016-08-09 | Astellas Pharma Inc. | Pharmaceutical composition for oral administration |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3732094A1 (de) * | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
DE4402933A1 (de) * | 1994-02-01 | 1995-08-03 | Kali Chemie Pharma Gmbh | Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
RU2254333C2 (ru) * | 1999-04-09 | 2005-06-20 | Астразенека Аб | Производные адамантана, способ их получения, фармацевтическая композиция на их основе и способы лечения |
SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
US6500457B1 (en) * | 2000-08-14 | 2002-12-31 | Peirce Management, Llc | Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent |
-
2001
- 2001-04-12 SE SE0101329A patent/SE0101329D0/xx unknown
-
2002
- 2002-04-01 TW TW091106495A patent/TWI257391B/zh not_active IP Right Cessation
- 2002-04-02 AR ARP020101187A patent/AR035806A1/es not_active Application Discontinuation
- 2002-04-12 AT AT02723011T patent/ATE332902T1/de not_active IP Right Cessation
- 2002-04-12 EE EEP200300495A patent/EE200300495A/xx unknown
- 2002-04-12 RU RU2003129230/15A patent/RU2003129230A/ru not_active Application Discontinuation
- 2002-04-12 US US10/474,584 patent/US20050037067A1/en not_active Abandoned
- 2002-04-12 MX MXPA03009209A patent/MXPA03009209A/es not_active Application Discontinuation
- 2002-04-12 EP EP02723011A patent/EP1389212B1/en not_active Expired - Lifetime
- 2002-04-12 JP JP2002581444A patent/JP2005500262A/ja not_active Withdrawn
- 2002-04-12 IL IL15803302A patent/IL158033A0/xx unknown
- 2002-04-12 DE DE60213084T patent/DE60213084T2/de not_active Expired - Fee Related
- 2002-04-12 SK SK1256-2003A patent/SK12562003A3/sk unknown
- 2002-04-12 KR KR10-2003-7013299A patent/KR20030088498A/ko not_active Application Discontinuation
- 2002-04-12 CA CA002443473A patent/CA2443473A1/en not_active Abandoned
- 2002-04-12 BR BR0208828-2A patent/BR0208828A/pt not_active IP Right Cessation
- 2002-04-12 CN CNA028116364A patent/CN1514839A/zh active Pending
- 2002-04-12 NZ NZ528561A patent/NZ528561A/en unknown
- 2002-04-12 CZ CZ20032774A patent/CZ20032774A3/cs unknown
- 2002-04-12 HU HU0303486A patent/HUP0303486A3/hu unknown
- 2002-04-12 WO PCT/SE2002/000726 patent/WO2002083689A1/en not_active Application Discontinuation
- 2002-04-12 PL PL02366629A patent/PL366629A1/xx not_active Application Discontinuation
-
2003
- 2003-10-03 ZA ZA200307756A patent/ZA200307756B/en unknown
- 2003-10-06 BG BG108234A patent/BG108234A/bg unknown
- 2003-10-09 NO NO20034529A patent/NO20034529L/no not_active Application Discontinuation
- 2003-10-10 IS IS6989A patent/IS6989A/is unknown
Also Published As
Publication number | Publication date |
---|---|
IL158033A0 (en) | 2004-03-28 |
HUP0303486A3 (en) | 2005-04-28 |
CN1514839A (zh) | 2004-07-21 |
AR035806A1 (es) | 2004-07-14 |
DE60213084T2 (de) | 2007-01-11 |
PL366629A1 (en) | 2005-02-07 |
CA2443473A1 (en) | 2002-10-24 |
NO20034529L (no) | 2003-12-08 |
EE200300495A (et) | 2003-12-15 |
TWI257391B (en) | 2006-07-01 |
RU2003129230A (ru) | 2005-04-10 |
HUP0303486A2 (hu) | 2004-01-28 |
CZ20032774A3 (cs) | 2004-01-14 |
NO20034529D0 (no) | 2003-10-09 |
SE0101329D0 (sv) | 2001-04-12 |
NZ528561A (en) | 2005-03-24 |
BG108234A (bg) | 2005-04-30 |
BR0208828A (pt) | 2004-03-09 |
US20050037067A1 (en) | 2005-02-17 |
KR20030088498A (ko) | 2003-11-19 |
EP1389212B1 (en) | 2006-07-12 |
EP1389212A1 (en) | 2004-02-18 |
SK12562003A3 (sk) | 2004-03-02 |
ATE332902T1 (de) | 2006-08-15 |
ZA200307756B (en) | 2005-01-03 |
DE60213084D1 (de) | 2006-08-24 |
WO2002083689A1 (en) | 2002-10-24 |
JP2005500262A (ja) | 2005-01-06 |
IS6989A (is) | 2003-10-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |