MXPA03004347A - Nuevos derivados de imidazol, metodo de produccion y uso de los mismos. - Google Patents
Nuevos derivados de imidazol, metodo de produccion y uso de los mismos.Info
- Publication number
- MXPA03004347A MXPA03004347A MXPA03004347A MXPA03004347A MXPA03004347A MX PA03004347 A MXPA03004347 A MX PA03004347A MX PA03004347 A MXPA03004347 A MX PA03004347A MX PA03004347 A MXPA03004347 A MX PA03004347A MX PA03004347 A MXPA03004347 A MX PA03004347A
- Authority
- MX
- Mexico
- Prior art keywords
- compound
- production method
- imidazole derivatives
- novel imidazole
- mixture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invencion proporciona un compuesto que tiene una actividad inhibidora sobre la esteroide C17,20-liasa, y util para el tratamiento y la profilaxis de un tumor, tal como prostatismo, cancer mamario y similares, y un metodo para separar eficientemente un compuesto opticamente activo de este compuesto de una mezcla de isomeros opticos del mismo, un compuesto de la formula:(Ver formula),en donde cada simbolo es como se definio en la especificacion, una sal del mismo o un profarmaco del mismo, y un metodo para obtener un compuesto opticamente activo separando opticamente una mezcla de isomeros opticos mediante el uso de un agente de separacion, tal como acido tartranilico y similares.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000351780 | 2000-11-17 | ||
| JP2001247618 | 2001-08-17 | ||
| JP2001336880 | 2001-11-01 | ||
| PCT/JP2001/010002 WO2002040484A2 (en) | 2000-11-17 | 2001-11-16 | Novel imidazole derivatives, production method thereof and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03004347A true MXPA03004347A (es) | 2004-05-04 |
Family
ID=27345219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03004347A MXPA03004347A (es) | 2000-11-17 | 2001-11-16 | Nuevos derivados de imidazol, metodo de produccion y uso de los mismos. |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7141598B2 (es) |
| EP (2) | EP1334106B1 (es) |
| JP (2) | JP3753971B2 (es) |
| KR (3) | KR100809899B1 (es) |
| CN (3) | CN100572363C (es) |
| AR (1) | AR034854A1 (es) |
| AT (2) | ATE327237T1 (es) |
| AU (3) | AU1429602A (es) |
| BR (1) | BR0115306B1 (es) |
| CA (1) | CA2429133C (es) |
| CY (1) | CY1105423T1 (es) |
| DE (1) | DE60119963T2 (es) |
| DK (1) | DK1334106T3 (es) |
| ES (1) | ES2260303T3 (es) |
| HK (1) | HK1056168A1 (es) |
| HU (1) | HU229408B1 (es) |
| IL (2) | IL155624A0 (es) |
| MX (1) | MXPA03004347A (es) |
| MY (1) | MY134929A (es) |
| NO (1) | NO326366B1 (es) |
| NZ (1) | NZ526387A (es) |
| PE (1) | PE20020596A1 (es) |
| PL (1) | PL204934B1 (es) |
| PT (1) | PT1334106E (es) |
| SI (1) | SI1334106T1 (es) |
| TW (1) | TWI306099B (es) |
| WO (1) | WO2002040484A2 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2275411A3 (en) * | 2002-01-10 | 2011-02-23 | Takeda Pharmaceutical Company Limited | Reformatsky Reagent in Stable Form and Process for Producing the Same |
| JP4745616B2 (ja) * | 2003-02-26 | 2011-08-10 | 武田薬品工業株式会社 | 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾール誘導体の安定化方法 |
| WO2004075890A1 (ja) * | 2003-02-26 | 2004-09-10 | Takeda Pharmaceutical Company | 安定化されたイミダゾール誘導体含有医薬組成物、イミダゾ－ル誘導体の安定化方法 |
| JP4837895B2 (ja) * | 2003-03-17 | 2011-12-14 | 武田薬品工業株式会社 | 放出制御組成物 |
| CA2519211A1 (en) * | 2003-03-17 | 2004-09-30 | Takeda Pharmaceutical Company Limited | Release control compositions |
| US7282507B2 (en) * | 2004-05-03 | 2007-10-16 | Janssen Pharmaceutica N.V. | Indole derivatives as selective androgen receptor modulators (SARMS) |
| AR049125A1 (es) * | 2004-05-28 | 2006-06-28 | Speedel Experimenta Ag | Heterociclos biciclicos nitrogenados inhibidores de la aromatasa. |
| EP1854463A4 (en) * | 2005-03-03 | 2011-03-23 | Takeda Pharmaceutical | COMPOSITION WITH CONTROLLED RELEASE |
| GT200600381A (es) | 2005-08-25 | 2007-03-28 | Compuestos organicos | |
| AR056888A1 (es) | 2005-12-09 | 2007-10-31 | Speedel Experimenta Ag | Derivados de heterociclil imidazol |
| EP1991223B1 (en) * | 2006-02-10 | 2010-07-14 | Janssen Pharmaceutica, N.V. | Novel imidazolopyrazole derivatives useful as selective androgen receptor modulators |
| TW200804284A (en) * | 2006-03-31 | 2008-01-16 | Speedel Experimenta Ag | Process for preparing 6,7-dihydro-5H-imidazo[1,5-a]pyridin-8-one |
| KR20100088144A (ko) * | 2007-10-29 | 2010-08-06 | 다케다 야쿠힌 고교 가부시키가이샤 | 공지된 암 치료법에 대해 난치성인 암의 예방 또는 치료에 사용하기 위한 피롤로 [1,2-ｃ] 이미다졸 유도체 |
| JOP20190231A1 (ar) * | 2009-01-15 | 2017-06-16 | Incyte Corp | طرق لاصلاح مثبطات انزيم jak و المركبات الوسيطة المتعلقة به |
| AR083916A1 (es) * | 2010-11-18 | 2013-04-10 | Takeda Pharmaceutical | Metodo para tratar el cancer de mama y cancer de ovarios |
| US20150157609A1 (en) | 2011-04-01 | 2015-06-11 | Takeda Pharmaceutical Company Limited | Solid preparation |
| WO2012173280A1 (en) * | 2011-06-15 | 2012-12-20 | Takeda Pharmaceutical Company Limited | Production method of imidazole derivatives |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728645A (en) * | 1982-12-21 | 1988-03-01 | Ciba-Geigy Corporation | Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors |
| NZ221729A (en) | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| ZA882717B (en) | 1987-04-22 | 1988-10-17 | Merrell Dow Pharmaceuticals Inc. | 17beta-(cyclopropylamino)-androst-5-eb-3beta-ol and related compounds useful as c17-20 lyase inhibitors |
| US5057521A (en) * | 1988-10-26 | 1991-10-15 | Ciba-Geigy Corporation | Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism |
| US4966898A (en) | 1989-08-15 | 1990-10-30 | Merrell Dow Pharmaceuticals Inc. | 4-substituted 17β-(cyclopropylamino)androst-5-en-3β-ol and related compounds useful as C17-20 lyase inhibitors |
| JPH06507355A (ja) | 1991-03-01 | 1994-08-25 | エレクトロスタティック テクノロジー インコーポレーテッド | 回路板用薄層板等を製造するための粉体コーティング法 |
| CA2127689A1 (en) * | 1992-01-27 | 1993-08-05 | Marcel A. C. Janssen | Pyrroloimidazolyl and imidazopyridinyl substituted 1h-benzimidazole derivatives as aromatase inhibitors |
| US5457102A (en) | 1994-07-07 | 1995-10-10 | Janssen Pharmaceutica, N.V. | Pyrroloimidazolyl and imidazopyridinyl substituted 1H-benzimidazole derivatives |
| NZ249911A (en) | 1992-03-31 | 1996-06-25 | British Tech Group | 17-(3-pyridyl) substituted steroids and use in pharmaceutical compositions |
| GB9310635D0 (en) | 1993-05-21 | 1993-07-07 | Glaxo Group Ltd | Chemical compounds |
| NZ273681A (en) | 1993-09-30 | 1996-09-25 | Yamanouchi Pharma Co Ltd | Fluoroenylmethylazole derivatives (including tricyclic ring systems where the middle ring is heterosubstituted) |
| WO1996014090A1 (en) | 1994-11-07 | 1996-05-17 | Janssen Pharmaceutica N.V. | Compositions comprising carbazoles and cyclodextrins |
| WO1997000257A1 (fr) | 1995-06-14 | 1997-01-03 | Yamanouchi Pharmaceutical Co., Ltd. | Derives d'imidazole fusionnes et composition medicinale les contenant |
| CA2281598A1 (en) | 1997-02-21 | 1998-08-27 | Tetsuya Aono | Fused ring compounds, process for producing the same and use thereof |
| DK1028110T3 (da) | 1997-10-02 | 2004-07-19 | Daiichi Seiyaku Co | Hidtil ukendte dihydronaphthalenforbindelser og fremgangsmåde til fremstilling deraf |
| ATE293102T1 (de) | 1998-04-23 | 2005-04-15 | Takeda Pharmaceutical | Naphthalene derivate ,ihre herstellung und verwendung |
| PE20010781A1 (es) * | 1999-10-22 | 2001-08-08 | Takeda Chemical Industries Ltd | Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion |
-
2001
- 2001-11-16 CN CNB2005100640723A patent/CN100572363C/zh not_active Expired - Fee Related
- 2001-11-16 MX MXPA03004347A patent/MXPA03004347A/es active IP Right Grant
- 2001-11-16 IL IL15562401A patent/IL155624A0/xx active IP Right Grant
- 2001-11-16 KR KR1020057018247A patent/KR100809899B1/ko active IP Right Grant
- 2001-11-16 US US10/416,986 patent/US7141598B2/en not_active Expired - Lifetime
- 2001-11-16 WO PCT/JP2001/010002 patent/WO2002040484A2/en active IP Right Grant
- 2001-11-16 DK DK01982800T patent/DK1334106T3/da active
- 2001-11-16 CA CA002429133A patent/CA2429133C/en not_active Expired - Fee Related
- 2001-11-16 ES ES01982800T patent/ES2260303T3/es not_active Expired - Lifetime
- 2001-11-16 DE DE60119963T patent/DE60119963T2/de not_active Expired - Lifetime
- 2001-11-16 PE PE2001001147A patent/PE20020596A1/es active IP Right Grant
- 2001-11-16 PT PT01982800T patent/PT1334106E/pt unknown
- 2001-11-16 MY MYPI20015279A patent/MY134929A/en unknown
- 2001-11-16 KR KR1020037006727A patent/KR100725442B1/ko active IP Right Grant
- 2001-11-16 PL PL362766A patent/PL204934B1/pl unknown
- 2001-11-16 EP EP01982800A patent/EP1334106B1/en not_active Expired - Lifetime
- 2001-11-16 HU HU0400549A patent/HU229408B1/hu not_active IP Right Cessation
- 2001-11-16 BR BRPI0115306-4B1A patent/BR0115306B1/pt not_active IP Right Cessation
- 2001-11-16 AU AU1429602A patent/AU1429602A/xx active Pending
- 2001-11-16 AR ARP010105365A patent/AR034854A1/es active IP Right Grant
- 2001-11-16 AU AU2002214296A patent/AU2002214296C1/en not_active Ceased
- 2001-11-16 JP JP2001351035A patent/JP3753971B2/ja not_active Expired - Fee Related
- 2001-11-16 EP EP05077705.1A patent/EP1681290B9/en not_active Expired - Lifetime
- 2001-11-16 CN CNB018190251A patent/CN1329394C/zh not_active Expired - Fee Related
- 2001-11-16 AT AT01982800T patent/ATE327237T1/de active
- 2001-11-16 NZ NZ526387A patent/NZ526387A/en not_active IP Right Cessation
- 2001-11-16 AT AT05077705T patent/ATE533768T1/de active
- 2001-11-16 SI SI200130590T patent/SI1334106T1/sl unknown
- 2001-11-16 CN CNA200610100666XA patent/CN1900079A/zh active Pending
- 2001-11-16 TW TW090128440A patent/TWI306099B/zh not_active IP Right Cessation
- 2001-11-16 KR KR1020077025704A patent/KR20080002929A/ko not_active Application Discontinuation
-
2003
- 2003-04-28 IL IL155624A patent/IL155624A/en not_active IP Right Cessation
- 2003-05-16 NO NO20032234A patent/NO326366B1/no not_active IP Right Cessation
- 2003-11-17 HK HK03108376A patent/HK1056168A1/xx not_active IP Right Cessation
-
2005
- 2005-08-31 JP JP2005252651A patent/JP4427496B2/ja not_active Expired - Fee Related
- 2005-10-18 AU AU2005225035A patent/AU2005225035B2/en not_active Ceased
-
2006
- 2006-06-26 CY CY20061100867T patent/CY1105423T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Change of company name or juridical status | ||
| FG | Grant or registration |