MXPA03003785A - Suspension de una proteina epi-hne, proceso de preparacion de la misma, aerosol en polvo seco derivado de la misma, composiciones farmaceuticas conteniendo dicha suspension o aerosol y sus usos. - Google Patents
Suspension de una proteina epi-hne, proceso de preparacion de la misma, aerosol en polvo seco derivado de la misma, composiciones farmaceuticas conteniendo dicha suspension o aerosol y sus usos.Info
- Publication number
- MXPA03003785A MXPA03003785A MXPA03003785A MXPA03003785A MXPA03003785A MX PA03003785 A MXPA03003785 A MX PA03003785A MX PA03003785 A MXPA03003785 A MX PA03003785A MX PA03003785 A MXPA03003785 A MX PA03003785A MX PA03003785 A MXPA03003785 A MX PA03003785A
- Authority
- MX
- Mexico
- Prior art keywords
- suspension
- aerosol
- dry powder
- epi
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Otolaryngology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invencion concierne a una suspension de particulas cristalizadas de una proteina EPI-hNE, metodos para preparar dicha suspension, un aerosol de polvo seco derivado de dicha suspension, una formulacion farmaceutica inhalable comprendiendo dicha suspension o dicho aerosol de polvo seco, y el uso de dicha formulacion farmaceutica inhalable en el tratamiento de varias condiciones patologicas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00403035A EP1201249A1 (en) | 2000-10-31 | 2000-10-31 | Suspension of EPI-HNE-4, dry powder aerosol derived therefrom, process of preparation thereof, pharmaceutical compositions containing said suspension or aerosol, and their uses |
EP01401731 | 2001-06-28 | ||
PCT/EP2001/012983 WO2002036158A1 (en) | 2000-10-31 | 2001-10-26 | Suspension of an epi-hne protein, process of preparation thereof, dry powder aerosol derived therefrom, pharmaceutical compositions containing said suspension or aerosol, and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA03003785A true MXPA03003785A (es) | 2004-04-20 |
Family
ID=26073607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA03003785A MXPA03003785A (es) | 2000-10-31 | 2001-10-26 | Suspension de una proteina epi-hne, proceso de preparacion de la misma, aerosol en polvo seco derivado de la misma, composiciones farmaceuticas conteniendo dicha suspension o aerosol y sus usos. |
Country Status (16)
Country | Link |
---|---|
US (1) | US6814982B2 (es) |
EP (1) | EP1223972B1 (es) |
JP (1) | JP2004512377A (es) |
KR (1) | KR100826342B1 (es) |
CN (2) | CN1287856C (es) |
AT (1) | ATE245445T1 (es) |
AU (2) | AU1701402A (es) |
BR (1) | BR0115020A (es) |
CA (1) | CA2426992A1 (es) |
DE (1) | DE60100500T2 (es) |
DK (1) | DK1223972T3 (es) |
ES (1) | ES2203601T3 (es) |
HK (1) | HK1048064B (es) |
MX (1) | MXPA03003785A (es) |
PT (1) | PT1223972E (es) |
WO (1) | WO2002036158A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
CA2488558C (en) | 2002-06-07 | 2013-08-20 | Dyax Corp. | Prevention and reduction of blood loss |
US20040265238A1 (en) * | 2003-06-27 | 2004-12-30 | Imtiaz Chaudry | Inhalable formulations for treating pulmonary hypertension and methods of using same |
WO2005021557A2 (en) * | 2003-08-29 | 2005-03-10 | Dyax Corp. | Poly-pegylated protease inhibitors |
US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
EP1830810A4 (en) * | 2004-12-30 | 2011-02-02 | Dobeel Co Ltd | SPRAY-DRYED COMPOSITION WITH PROTEINS OF THE COLLECTIN FAMILY OR VARIATIONS THEREOF AND METHOD OF PREPARATION THEREOF |
CA2696208A1 (en) * | 2007-08-21 | 2009-02-26 | Genzyme Corporation | Treatment with kallikrein inhibitors |
WO2010080833A1 (en) | 2009-01-06 | 2010-07-15 | Dyax Corp. | Treatment of mucositis with kallikrein inhibitors |
SI2521568T1 (sl) | 2010-01-06 | 2019-01-31 | Dyax Corp. | Proteini, ki vežejo plazemski kalikrein |
IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | KALLIKREIN PLASMA BINDING PROTEINS |
BR112016022318A2 (pt) | 2014-03-27 | 2017-10-31 | Dyax Corp | método, composição farmacêutica para uso no tratamento de doenças de retina e uso de um anticorpo |
JP7003354B2 (ja) | 2015-12-11 | 2022-03-04 | 武田薬品工業株式会社 | 遺伝性血管性浮腫の発作を治療するための血漿カリクレイン阻害薬およびその用途 |
CN110141561A (zh) * | 2018-03-29 | 2019-08-20 | 中国人民解放军军事科学院军事医学研究院 | 一种可气溶胶化蛋白干粉吸入剂的制备技术 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5663143A (en) * | 1988-09-02 | 1997-09-02 | Dyax Corp. | Engineered human-derived kunitz domains that inhibit human neutrophil elastase |
US5148381A (en) * | 1991-02-07 | 1992-09-15 | Intel Corporation | One-dimensional interpolation circuit and method based on modification of a parallel multiplier |
ES2124203T3 (es) * | 1991-03-01 | 2004-04-16 | Dyax Corp. | Inhibidores de la elastasa neutrofila humana y la catepsina g humana. |
EP1184393A1 (en) | 2000-09-04 | 2002-03-06 | Debiopharm S.A. | Process for the purification of EPI-HNE proteins |
-
2001
- 2001-10-26 EP EP01992586A patent/EP1223972B1/en not_active Expired - Lifetime
- 2001-10-26 BR BR0115020-0A patent/BR0115020A/pt not_active IP Right Cessation
- 2001-10-26 JP JP2002538967A patent/JP2004512377A/ja active Pending
- 2001-10-26 AU AU1701402A patent/AU1701402A/xx active Pending
- 2001-10-26 AU AU2002217014A patent/AU2002217014B2/en not_active Ceased
- 2001-10-26 MX MXPA03003785A patent/MXPA03003785A/es active IP Right Grant
- 2001-10-26 ES ES01992586T patent/ES2203601T3/es not_active Expired - Lifetime
- 2001-10-26 AT AT01992586T patent/ATE245445T1/de not_active IP Right Cessation
- 2001-10-26 WO PCT/EP2001/012983 patent/WO2002036158A1/en active IP Right Grant
- 2001-10-26 DK DK01992586T patent/DK1223972T3/da active
- 2001-10-26 CN CNB2004100856047A patent/CN1287856C/zh not_active Expired - Fee Related
- 2001-10-26 CN CNB01818118XA patent/CN100396329C/zh not_active Expired - Fee Related
- 2001-10-26 CA CA002426992A patent/CA2426992A1/en not_active Abandoned
- 2001-10-26 KR KR1020037005928A patent/KR100826342B1/ko not_active IP Right Cessation
- 2001-10-26 DE DE60100500T patent/DE60100500T2/de not_active Expired - Lifetime
- 2001-10-26 PT PT01992586T patent/PT1223972E/pt unknown
-
2003
- 2003-01-03 HK HK03100036.3A patent/HK1048064B/zh not_active IP Right Cessation
- 2003-04-17 US US10/417,854 patent/US6814982B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1636595A (zh) | 2005-07-13 |
DE60100500T2 (de) | 2004-04-15 |
WO2002036158A8 (en) | 2004-03-04 |
DK1223972T3 (da) | 2003-11-03 |
CN1287856C (zh) | 2006-12-06 |
ES2203601T3 (es) | 2004-04-16 |
US6814982B2 (en) | 2004-11-09 |
EP1223972A1 (en) | 2002-07-24 |
KR100826342B1 (ko) | 2008-05-02 |
HK1048064B (zh) | 2004-02-13 |
HK1048064A1 (en) | 2003-03-21 |
BR0115020A (pt) | 2003-12-23 |
AU2002217014B2 (en) | 2006-11-02 |
WO2002036158A1 (en) | 2002-05-10 |
ATE245445T1 (de) | 2003-08-15 |
DE60100500D1 (de) | 2003-08-28 |
EP1223972B1 (en) | 2003-07-23 |
CA2426992A1 (en) | 2002-05-10 |
CN1471405A (zh) | 2004-01-28 |
KR20030059809A (ko) | 2003-07-10 |
AU1701402A (en) | 2002-05-15 |
US20040013659A1 (en) | 2004-01-22 |
JP2004512377A (ja) | 2004-04-22 |
PT1223972E (pt) | 2003-11-28 |
CN100396329C (zh) | 2008-06-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |