MXPA02012911A - Compuestos de rutenio (ii) para el uso en terapia del cancer. - Google Patents

Compuestos de rutenio (ii) para el uso en terapia del cancer.

Info

Publication number
MXPA02012911A
MXPA02012911A MXPA02012911A MXPA02012911A MXPA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A MX PA02012911 A MXPA02012911 A MX PA02012911A
Authority
MX
Mexico
Prior art keywords
cancer
compounds
ruthenium
therapy
saturated
Prior art date
Application number
MXPA02012911A
Other languages
English (en)
Inventor
Haimei Chen
Original Assignee
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Glasgow filed Critical Univ Glasgow
Publication of MXPA02012911A publication Critical patent/MXPA02012911A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0046—Ruthenium compounds

Abstract

Los compuestos que se pueden usar en el tratamiento y/o prevencion de cancer, los cuales tienen la formula (I); en donde R1 y R2 junto con el anillo al cual estan unidos representan un grupo carbociclico o heterociclico saturado o insaturado.
MXPA02012911A 2000-06-30 2001-06-26 Compuestos de rutenio (ii) para el uso en terapia del cancer. MXPA02012911A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0016052.3A GB0016052D0 (en) 2000-06-30 2000-06-30 Ruthenium (II) compounds
PCT/GB2001/002824 WO2002002572A1 (en) 2000-06-30 2001-06-26 Ruthenium (ii) compounds for use in the therapy of cancer

Publications (1)

Publication Number Publication Date
MXPA02012911A true MXPA02012911A (es) 2004-07-30

Family

ID=9894730

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012911A MXPA02012911A (es) 2000-06-30 2001-06-26 Compuestos de rutenio (ii) para el uso en terapia del cancer.

Country Status (14)

Country Link
US (1) US6936634B2 (es)
EP (1) EP1294732B1 (es)
JP (1) JP2004502696A (es)
AT (1) ATE273985T1 (es)
AU (1) AU2001267687A1 (es)
BR (1) BR0112122A (es)
CA (1) CA2414446A1 (es)
DE (1) DE60105028T2 (es)
DK (1) DK1294732T3 (es)
ES (1) ES2227225T3 (es)
GB (1) GB0016052D0 (es)
MX (1) MXPA02012911A (es)
PT (1) PT1294732E (es)
WO (1) WO2002002572A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1224192B1 (en) * 1999-10-27 2005-08-31 The University Court, The University Of Edinburgh Half-sandwich ruthenium (ii) compounds comprising nitrogen containing ligands for treatment of cancer
WO2003049760A1 (en) * 2001-12-07 2003-06-19 Intermune, Inc. Compositions and method for treating hepatitis virus infection
GB0215526D0 (en) * 2002-07-05 2002-08-14 Univ Edinburgh Anticancer compounds
MXPA05011653A (es) 2003-04-30 2006-06-27 Univ Edinburgh Complejos de rutenio (ii) para el tratamiento de tumores.
GB0418643D0 (en) * 2004-08-20 2004-09-22 Univ Edinburgh Ruthenium (II) compounds
GB0604602D0 (en) * 2006-03-07 2006-04-19 Univ Edinburgh Ruthenium (II) compounds
GB0610062D0 (en) * 2006-05-19 2006-06-28 Univ Edinburgh Ruthenium (ll) compounds
CN101851256B (zh) * 2010-04-30 2013-01-09 广东药学院 一种以柔性碳链联接的钌(ⅱ)卟啉配合物及其制备方法和应用
CN101863925B (zh) * 2010-05-21 2012-08-29 广东药学院 一种芳基钌(ⅱ)配合物及其制备方法和应用
US9751081B2 (en) 2014-12-01 2017-09-05 Clemson University Self-regenerating antioxidant catalysts and methods of using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980472A (en) 1983-06-23 1990-12-25 American Cyanamid Company Method of making (3-amino-1H-pyrazol-4-yl) (aryl)methanones
AU570826B2 (en) 1984-07-24 1988-03-24 Asta-Pharma Aktiengesellschaft Ruthenium compounds having a tumor inhibiting activity
EP0188585A1 (de) 1984-07-24 1986-07-30 Byk Gulden Lomberg Chemische Fabrik GmbH Tumorhemmend wirkende rutheniumverbindungen
US4980473A (en) * 1985-01-18 1990-12-25 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and chiral metal complexes as Z-specific anti-tumor agents
US4699978A (en) 1985-01-18 1987-10-13 The Trustees Of Columbia University In The City Of New York Site-specific chiral ruthenium (II) and cobalt (III) antitumor agents
US5225556A (en) 1985-01-18 1993-07-06 The Trustees Of Columbia University In The City Of New York Chemical probes for left-handed DNA and for A-DNA; chiral metal complexes as Z-specific antitumor agents and as double strand cleavers
AU4017695A (en) 1994-10-28 1996-05-23 Procept, Inc. Ruthenium complexes and their use as immunosuppressive agents
JPH11209314A (ja) 1997-09-30 1999-08-03 Takasago Internatl Corp シクロオクタジエン類の製造方法
JP3488103B2 (ja) * 1998-11-12 2004-01-19 高砂香料工業株式会社 ４−メチル−５−ヘキセン−１−アールを含有する香料組成物
GB0028025D0 (en) 2000-11-17 2001-01-03 Univ York Compounds

Also Published As

Publication number Publication date
EP1294732B1 (en) 2004-08-18
US20040029852A1 (en) 2004-02-12
US6936634B2 (en) 2005-08-30
PT1294732E (pt) 2004-12-31
CA2414446A1 (en) 2002-01-10
WO2002002572A1 (en) 2002-01-10
AU2001267687A1 (en) 2002-01-14
DE60105028D1 (de) 2004-09-23
GB0016052D0 (en) 2000-08-23
BR0112122A (pt) 2003-05-13
EP1294732A1 (en) 2003-03-26
DK1294732T3 (da) 2004-12-06
ES2227225T3 (es) 2005-04-01
JP2004502696A (ja) 2004-01-29
DE60105028T2 (de) 2005-08-18
ATE273985T1 (de) 2004-09-15

Similar Documents

Publication Publication Date Title
MY138059A (en) Use of ikb-kinase inhibitors in pain therapy
ES2170252T3 (es) Tetrahidroimidazopiridoindoldionas como inhibidores de cgmp especifico pde.
ATE461217T1 (de) Glp-1-verbindungen
BG108269A (en) Pyrazolopyrimidines as therapeutic agents
DK1365808T3 (da) Sammensætninger til antitumorbehandling indeholdende ecteinascidin 743
ZA200500908B (en) Ruthenium anticancer complexes
MXPA03002911A (es) Compuestos quimicos.
MXPA02012076A (es) Compuestos quimicos.
MY138883A (en) Use of asiatic acid for treatment of cencer
MXPA02012659A (es) Derivados de pirazindiona condensados.
HK1076812A1 (en) Cyanoguanidine prodrugs
MXPA06000701A (es) Compuestos de sulfonildihidrobencimidazolona como ligandos de 5-hidroxitriptamina-6.
MXPA02012911A (es) Compuestos de rutenio (ii) para el uso en terapia del cancer.
IL150125A0 (en) Novel compounds
IL135825A0 (en) Use of mirtazapine for treating sleep apneas
AR020563A1 (es) Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion
NZ528164A (en) Use of flumazenil to produce a medicament for the treatment of ***e dependency
GB0027705D0 (en) Novel compounds
TW200504051A (en) Novel acridine derivatives and their use as medicaments
PT1303520E (pt) Compostos terapêuticos e métodos
MXPA02012472A (es) Compuestos quimicos.
MX2008001548A (es) Compuestos antitumorales.
SI1003554T1 (en) Proton pump inhibitor in therapeutic combination with antibacterial substances
RS52038B (en) USE OF 7-BUTOXYIMINOMETHYLAMPTOTECIN FOR THE TREATMENT OF NON-PLASMA NEOPLASMS
SI1358182T1 (en) Diazocine derivates and their use as tryptase inhibitors

Legal Events

Date Code Title Description
FG Grant or registration