MXPA02012039A - Composiciones en polvo. - Google Patents

Composiciones en polvo.

Info

Publication number
MXPA02012039A
MXPA02012039A MXPA02012039A MXPA02012039A MXPA02012039A MX PA02012039 A MXPA02012039 A MX PA02012039A MX PA02012039 A MXPA02012039 A MX PA02012039A MX PA02012039 A MXPA02012039 A MX PA02012039A MX PA02012039 A MXPA02012039 A MX PA02012039A
Authority
MX
Mexico
Prior art keywords
drying
powder
compositions
prepared
spray
Prior art date
Application number
MXPA02012039A
Other languages
English (en)
Inventor
Steven Joseph Prestrelski
Original Assignee
Powderject Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Powderject Vaccines Inc filed Critical Powderject Vaccines Inc
Publication of MXPA02012039A publication Critical patent/MXPA02012039A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Se describe in polvo de flujo libre formador de gel adecuado para su uso como una vacuna que se prepara por secado por rociado o secado por congelacion y rociado de una suspension acuosa que contiene un antígeno absorbido en un adyuvante de una sal de aluminio o una sal de calcio, un sacárido, un aminodcido o una sal del mismo, y una substancia coloidal. El polvo para los propositos de vacuna, tambidn se prepara por secado por congelacion y rociado de una suspension acuosa de tal adyuvante que tiene un antígeno absorbido en él. Se describen también los procesos para la formacion de estas composiciones en polvo, así como los métodos de uso de las composiciones en un procedimiento de vacunacion.
MXPA02012039A 2000-06-08 2001-06-08 Composiciones en polvo. MXPA02012039A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59077700A 2000-06-08 2000-06-08
US21058100P 2000-06-08 2000-06-08
PCT/US2001/018494 WO2001093829A2 (en) 2000-06-08 2001-06-08 Powder compositions

Publications (1)

Publication Number Publication Date
MXPA02012039A true MXPA02012039A (es) 2003-06-06

Family

ID=26905296

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012039A MXPA02012039A (es) 2000-06-08 2001-06-08 Composiciones en polvo.

Country Status (11)

Country Link
EP (1) EP1289494A2 (es)
JP (1) JP2003535119A (es)
KR (1) KR20030020294A (es)
CN (1) CN1438874A (es)
AU (1) AU2001275371B9 (es)
BR (1) BR0111494A (es)
CA (1) CA2412197A1 (es)
IL (1) IL153241A0 (es)
MX (1) MXPA02012039A (es)
NZ (2) NZ523103A (es)
WO (1) WO2001093829A2 (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1399131A2 (en) 2001-06-08 2004-03-24 Powderject Vaccines, Inc. Spray freeze-dried compositions
EP1458362A4 (en) * 2001-11-19 2006-01-18 Becton Dickinson Co PHARMACEUTICAL COMPOSITIONS IN PARTICLE FORM
US7923029B2 (en) 2002-04-11 2011-04-12 Medimmune Llc Spray freeze dry of compositions for pulmonary administration
DE10339197A1 (de) * 2003-08-22 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität
TW200626177A (en) * 2004-09-28 2006-08-01 Alza Corp Method and formulation for stabilizing alum-adsorbed vaccines
JP5349043B2 (ja) * 2005-06-27 2013-11-20 アプライド シン フィルムズ，インコーポレイティッド 燐酸アルミニウム系マイクロスフェア
EP1933867A1 (en) 2005-10-04 2008-06-25 Alk-Abello A/S Solid vaccine formulation
CA2628084A1 (en) * 2005-11-01 2007-05-10 Novartis Ag Compositions with antigens adsorbed to calcium phosphate
WO2008079464A2 (en) * 2006-09-08 2008-07-03 Becton, Dickinson And Company Stable powder formulations of alum-adsorbed vaccines
CA2702340C (en) 2006-10-12 2014-12-16 The University Of Queensland Compositions and methods for modulating immune responses
EP2829282B1 (en) * 2007-03-22 2017-10-25 The Regents of The University of Colorado, A Body Corporate Method of preparing an immunologically-active adjuvant-bound dried vaccine composition
EP2182922A4 (en) * 2007-07-26 2010-07-28 Sanofi Pasteur Ltd ANTIGEN-ADJUVANS COMPOSITIONS AND METHOD
CN101959527B (zh) 2008-03-05 2016-04-20 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法
CA2738621C (en) 2008-10-02 2017-01-31 Pharmathene Inc. Anthrax vaccine formulation and uses thereof
GB2490644A (en) 2010-03-31 2012-11-07 Stabilitech Ltd Excipients for stabilising viral particles, polypeptides or biological material
KR101819250B1 (ko) 2010-03-31 2018-01-16 스타빌리테크 리미티드 알룸 아쥬반트 및 알룸 아쥬반트를 포함하는 백신의 보존방법
ES2543795T3 (es) 2010-03-31 2015-08-21 Stabilitech Ltd. Estabilización de partículas virales
CN103328499A (zh) 2010-11-01 2013-09-25 悉尼科技大学 免疫调节剂及其用途
KR102023207B1 (ko) 2010-12-02 2019-11-25 온콜리틱스 바이오테크 인코포레이티드 동결건조 바이러스 제형
EA201390810A1 (ru) 2010-12-02 2013-09-30 Онколитикс Байотек Инк. Жидкие вирусные составы
CN102133396B (zh) * 2011-03-16 2013-10-16 中国人民解放军第三〇二医院 一种疫苗注射剂及其制备方法
GB201117233D0 (en) 2011-10-05 2011-11-16 Stabilitech Ltd Stabilisation of polypeptides
BR112014020930A2 (pt) * 2012-03-05 2017-06-27 De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport método para produzir uma formulação seca de um agente biofármaco, e, formulação de um agente biofármaco
KR101441539B1 (ko) * 2013-04-01 2014-09-18 재단법인 유타 인하 디디에스 및 신의료기술개발 공동연구소 흡습성이 개선된 접착제 조성물 및 이의 제조방법
CN103641886B (zh) * 2013-11-26 2015-07-29 精晶药业股份有限公司 一种丙谷二肽的精制方法
GB201406569D0 (en) 2014-04-11 2014-05-28 Stabilitech Ltd Vaccine compositions
GB2562241B (en) 2017-05-08 2022-04-06 Stabilitech Biopharma Ltd Vaccine compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2505657A1 (fr) * 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation
HU188847B (en) * 1983-02-22 1986-05-28 Human Oltoanyagtermeloe Es Kutato Intezet,Hu Process for producing liophylized combined vaccines
JPS6013718A (ja) * 1983-07-05 1985-01-24 Chemo Sero Therapeut Res Inst Ｂ型肝炎ワクチン
EP0676088A1 (en) * 1992-12-28 1995-10-11 YU, Shih-Chiang Non-volatile semiconductor memory cell
NZ259285A (en) * 1993-01-08 1996-07-26 Csl Ltd Vaccine preparations in stable particulate form comprising an immunogen absorbed to an aluminium salt adjuvant or biodegradable polymer matrix
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5902565A (en) * 1993-12-24 1999-05-11 Csl Limited Spray dried vaccine preparation comprising aluminium adsorbed immunogens
RU2096042C1 (ru) * 1996-11-06 1997-11-20 Виктор Иванович Ситьков Способ получения поливалентной вакцины против лептоспироза животных
WO1999027961A1 (en) * 1997-12-02 1999-06-10 Powderject Vaccines, Inc. Transdermal delivery of particulate vaccine compositions

Also Published As

Publication number Publication date
BR0111494A (pt) 2004-01-13
EP1289494A2 (en) 2003-03-12
CA2412197A1 (en) 2001-12-13
WO2001093829A2 (en) 2001-12-13
AU2001275371B2 (en) 2006-12-21
NZ552576A (en) 2008-06-30
AU7537101A (en) 2001-12-17
KR20030020294A (ko) 2003-03-08
JP2003535119A (ja) 2003-11-25
WO2001093829A3 (en) 2002-06-13
CN1438874A (zh) 2003-08-27
NZ523103A (en) 2005-08-26
AU2001275371B9 (en) 2007-06-07
IL153241A0 (en) 2003-07-06

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