MXPA02000481A - Cosmetic compositions. - Google Patents

Abstract

According to the present invention there is provided a cosmetic composition comprising: (a) at least one quaternary ammonium agent; and (b) at least one sunscreen active. The compositions of the present invention give sun protection benefits with low tackiness or stickiness. Moreover, the compositions of the present invention can give good skin care benefits with low levels of negatives such as greasiness, stickiness or tack.

Description

COSMETIC COMPOSITIONS TECHNICAL FIELD The present invention relates to 5 cosmetic compositions. In particular, the present invention relates to cosmetic compositions that provide good moisturization, hydration, a pleasant feeling on the skin and the benefits of softness and / or smoothness of the skin while protecting against deterioration caused by ultraviolet radiation on the skin.

BACKGROUND OF THE INVENTION The skin is formed by several layers of cells, 15 which coat and protect the fibrous proteins of keratin and collagen that form the skeleton of its structure. It is known that the outermost of these layers, referred to as the corneal layer (stratum corneum), is composed of 25 nm protein packages surrounded by 20 layers of 8 nm thickness. Anionic surfactants and organic solvents typically penetrate the corneal layer membrane (stratum corneum) and, by means of delipidation (for example the separation of lipids from the stratum corneum), destroy their integrity. 25 This destruction of the surface topography of the skin Pl 39 I faith »" it leads to a rough sensation and can, eventually, allow the surfactant or solvent to interact with the keratin, creating an irritation. Many people expose their skin to this type of mistreatment day by day. In addition, the skin can also be deteriorated by environmental factors such as exposure to cold air or wind, mechanical abrasion, immersion in water, etc. However, the most common way of skin deterioration due to environmental factors is related to exposure to radiation 10 ultraviolet, specifically to the radiation that emanates from the sun. Accordingly, there is a need for a way to mitigate or lessen the deterioration of the skin. Previously, compositions intended to assist the stratum corneum have been formulated for 15 to maintain its water barrier and retention functions in an optimal performance, despite the harmful interactions to which the skin could be exposed in washing, work and recreation. The desirable properties of these compositions are that they have characteristics of a 20 pleasant feeling on the skin, water retention, wetting, absorption and / or that can be rubbed. The compositions of the prior art have attempted to confer these properties through the use of one or more 'skin care agents'. For example, a way to 25 grant a high moisture to the skin is to incorporate Pl 39 i-y1 1? liiÁ-, í-t í líií rl -, t? i? gáÍl ^? ?? ^? u ^^^^^^^^^^^^^ U¡ tí tttßlM ^^? ÉU ^^^ ?? humectant materials similar to polyhydric alcohol such as glycerin, in the composition. Dermatological compositions with high levels of polyhydric alcohols and, therefore, high levels of wetting, however, are frequently perceived by the consumer as unpleasant because this class of compositions can give the feeling of being sticky when applied to the skin . Another way of providing desirable benefits to the skin is to incorporate emollient materials such as, for example, esters of polyolcarboxylic acids in the skin care compositions. However, this class of compositions may have negative effects in terms of skin sensation (for example, they often produce a very greasy feeling on the skin) as well as poor ability to rub, poor absorption and residue-leaving characteristics. It has been found that there is a direct relationship between the amount of skin care agent and the effectiveness of the composition with respect to providing benefits to the skin. However, it is also the case that the higher the level of agent for skin care, the greater the risk of associated negative effects. Consequently, to date, it has been necessary to make a balance of the benefits provided by the compositions comprising levels Pl 39 .,.,.,.,,,,,,,.,.,.,.,.,.,.,.,.,.,. of the agents for the care of the skin with respect to the negative effects associated with high levels of this class of agents. Therefore, there remains a need for compositions containing high levels of skin care agents and, consequently, providing high levels of moisturization and hydration as well as providing the benefits of an excellent skin feel, softness and smoothness in the skin, but showing low levels of associated negative effects such as greasy sensation, sticky feeling or adhesiveness. Quaternary ammonium agents are known with respect to their use in cosmetic compositions. See, for example, WO-A-99/27904, OA-96/32089 and EP-A-789, 076. Also, US-A-5, 804, 205 which discloses compositions for dermatological care claimed for provide a high degree of wetting without leaving "adhesive" or "sticky" residues. The compositions contain quaternary ammonium compounds having two alkyl groups of 16-22 carbon atoms, humectants and non-irritating hydrophobic microspheres having an average particle size of less than 50 μm. It is claimed that the hydrophobic polymer microspheres significantly reduce the "sticky feel" associated with high levels of humectants. The compositions of US- Pl 39 ^ ?? i ?? i ^, ** »^. ^. ..... ......

A-5,804,205 may also contain low levels of emollients such as petrolatum or mineral oil. The materials that provide protection against deterioration caused by solar radiation are also well known for use in cosmetic compositions. See, for example, EP-A992455, EP-A-953336, O-A-97/29735 and US-A-5989529, all of which disclose compositions with sunscreen. However, compositions of the prior art can often produce a sensation 10 sticky when applied and it is known to be difficult to achieve a uniform application of the active ingredient of the sunscreen. It has now been found, unexpectedly, that the compositions comprising 15 minus a quaternary ammonium agent and an active sunscreen ingredient can provide a smooth and uniform application of the active ingredient of the sunscreen with low levels of associated negative effects. In addition, the present compositions may include high levels 20 of skin care agents to provide benefits such as a pleasant feeling on the skin, smoothness and smoothness of the skin, but showing low levels of negative effects such as greasy feeling, sticky feeling or stickiness. 25 Trying not to be limited by theory, you P1439 ^ thinks that the quaternary ammonium agents of the present invention can be vesicular to the active ingredients of the sunscreen and conduct their deposition on the skin, thereby ensuring that they are applied more evenly on the skin without the adhesiveness / tacky feel generally associated with these compositions. Furthermore, it is thought that the quaternary ammonium agents of the present invention can emulsify the emollients, which ensures that the emollient is applied in a more efficient manner. 10 uniform on the skin and that the greasy / adhesive / sticky feel is minimized. The quaternary ammonium agents help reduce the loss of sunscreen and / or moisturizers / emollients from the skin due to environmental factors such as water or abrasion. On the other hand, 15 thinks that the quaternary ammonium agents alone administer skin care benefits such as good wetting, pleasant skin feeling, softness of the skin.

SUMMARY OF THE INVENTION According to the present invention, there is provided a cosmetic composition comprising: (a) at least one quaternary ammonium agent; and 25 (b) at least one active ingredient of a P1439 ÍM ttá, * A ~ * St? & > . , M .. »* F -,.,. - .....» ...., ..._... 1 || 1 ^ m sunscreen. The compositions of the present invention provide the benefits of sun protection with low tack or sticky feel. On the other hand, the compositions of the present invention may provide benefits for good skin care with low levels of negative effects such as greasiness, stickiness or stickiness.

DETAILED DESCRIPTION OF THE INVENTION The compositions of the present invention comprise at least one quaternary ammonium agent and at least one active ingredient of a sunscreen. These elements will be described in more detail below. The present compositions can be used for any suitable purpose. In particular, the present compositions are suitable for topical application on the skin. In particular, the skin care compositions can be in the form of creams, lotions, gels and the like. Preferably, the cosmetic compositions of this invention are in the form of an oil-in-water emulsion with one or more oil phases in a continuous aqueous phase, each oil phase comprising a single oily component or P1439 a mixture of oily components in a miscible or homogeneous form but different oil phases containing different materials or combinations of materials from each. The compositions of the present invention preferably comprise several vesicles. Preferably, the vesicles comprise quaternary ammonium compounds together with an active sunscreen ingredient. Preferably, the compositions of the present invention comprise less than 10%, preferably less than 5%, more preferably less than 3%, even more preferably 0% by weight, of an anionic surfactant. The compositions of the present invention are preferably formulated such that they have a product viscosity of at least about 1,000 mPa.s and preferably within the range of about 1,000 to about 300,000 mPa.s, with greater preference of about 2,500 to about 250,000 mPa. s and especially from about 5,000 to about 200,000 mPa. s (26.8 ° C, pure, Brookfield DV-II + Spindle CP52 / CP41).

Quaternary ammonium agent The compositions of the present invention should comprise at least one quaternary ammonium agent.

Pl439 Any quaternary ammonium agent suitable for use in cosmetic compositions can be used in this invention. As the term "quaternary ammonium agent" is used, it means a compound or mixture of compounds having a quaternary nitrogen atom substituted with one or more, preferably two, fractions containing six or more carbon atoms. of quaternary ammonium which are used in this invention are selected from those having a quaternary nitrogen substituted with two fractions, wherein each fraction comprises ten or more, preferably 12 or more, carbon atoms.The highly preferred quaternary ammonium agents which used in this invention are selected from those that have the ability to form vesicles in polar solvents, detected by means of microscopic analysis (polarized light microscope at x60 magnification using a Nikon Eclipse E800 microscope) .As used in this invention , the term "vesicle" means one or more bilayers arranged in a closed geometry, g Generally spherical, the bilayer comprises a quaternary ammonium agent as described below. Preferably, the present compositions comprise at least 0.01%, more preferably at least 0.1%, even more preferably at least 1%, P1439 .. M ^ .J-J ^ .- still more preferably at least 3%, by weight, of quaternary ammonium agent. Preferably the quaternary ammonium agents that are used in this invention are selected from the group comprising: (a) quaternary ammonium compounds according to the general formula (I): (l) wherein Ri and R2 are each alkyl groups (C? -C4) or hydroxyalkyl groups (C? -C4) or hydrogen. Ri and R3 are each alkyl groups or alkenyl groups with about 8 to about 22 carbon atoms. X "is a salt-forming anion compatible with quaternary ammonium compounds and other adjunct ingredients.The preferred quaternary ammonium compounds of this class are quaternized amines having the general formula (I), wherein Ri and R2 are methyl or hydroxyethyl, and R3 and R4 are alkyl or alkenyl chains P1439 - > »-_- > - > ^^^^^^^ A ^ j linear or branched comprising at least 11 atoms, preferably at least 15 carbon atoms, (b) quaternary ammonium compounds according to the general formula (II) or (III): (R5) 4- m N + -f (CH2) n Q R6) m X "(ll) (R5) 4- N + - (CH2) n- - wherein each R 5 unit is independently selected from the group consisting of hydrogen, straight or branched chain (C? -C6) alkyl, hydroxyalkyl (C? -C6) straight or branched chain and mixtures thereof , preferably methyl and hydroxyethyl; each R6 unit is independently a linear or branched (C11-C22) alkyl, straight or branched (Cn-C22) alkenyl, and mixtures thereof; X "is an anion that is compatible with the active ingredients for skin care and with the adjunct ingredients; m is a number from 1 to 4, preferably 2; n is a number from 1 to 4, preferably 2 and Q is a carbonyl unit selected from the group consisting of: P1439 i - «. Jti -.-? - -iiJ, ia > , Aat-. My fa * O -O- C- -CO- -O-C-O- O R7 10 -C-N-, and wherein R7 is hydrogen, (C? -C4) alkyl, hydroxyalkyl (Cx-15 C4) and mixtures thereof. In the above example of the quaternary ammonium compound, the -QR6 unit contains a fatty acyl unit, which is typically derived from a triglyceride source. The source of triglycerides is derived from 20 Sebum preference, partially hydrogenated tallow, lard P1439 ..tií.y.? .........-...-, -. - »" * - ----- 'pork, partially hydrogenated lard, vegetable oils and / or partially hydrogenated vegetable oils such as, for example, canola oil, safflower oil, peanut oil, rape seed oil , sunflower oil, corn oil, soybean oil, resin oil, rice bran oil, etc. and mixtures of these oils.The counterion, X "of the above compounds, can be any compatible anion, preferably the anion of a strong acid, for example, chloride, bromide, methylisulfate, ethylsulfate, sulfate, nitrate and the like, more preferably chloride or methylisulfate. The anion can also, but less preferred, carry a double charge, in which case X "represents half a group.The preferred quaternary ammonium compounds of the present invention are diester and / or quaternary ammonium diamide (DEQA) compounds, the diesters and diamides having general formula (II), wherein the carbonyl group Q is selected from: - C - or -. and P1439 Sebum and canola and palm oils are convenient and inexpensive sources of fatty acyl units suitable for use in the present invention as R6 units. The counterion X "can be chloride, bromide, methylisulfate, formate, sulfate, nitrate and mixtures thereof In fact, the anion X" is only present as a counter-ion of the positively charged quaternary ammonium compounds. The scope of the present invention is not supposed to be limited to any particular anion. As used in this invention, when the diester is specified, it will include the monoester and triester which are generally present as a result of the manufacturing process. (c) quaternary ammonium compounds according to the general formula (IV) or (V): P1439 (iv) (V) wherein R9 is a group of an aliphatic acyclic hydrocarbon C? 5-C2? and Ri0 is an alkyl or alkylene (C? -C6). These ammonium compounds, which have a pKa value of no greater than about 4, have the ability to generate a cationic charge in itself when dispersed in an aqueous solution, provided that the pH of the final composition is not higher than approximately 6. (d) quaternary ammonium compounds according to the general formula (VI) or (VII): P1439 Li. wherein R9 and Ri0 are as specified above in this invention and R1X is selected from the groups alkyl and hydroxyalkyl (C? -C4). The counterion X "can be chloride, bromide, methylisulfate, formate, sulfate, nitrate and mixtures thereof In fact, the anion X" is only present as a counter-ion of the positively charged quaternary ammonium compounds. The scope of the present invention is not supposed to be limited to any particular anion. (e) quaternary ammonium compounds according to the general formula (VIII) or (IX): P1439 - - - • • * '* i - * - * • -. (VIII (IX) wherein, n is a number from 1 to 6, R9 is selected from C6-C2 aliphatic acyclic hydrocarbon groups? Y ? it is selected from alkyl and hydroxyalkyl groups (C? -C4). These ammonium compounds (VIII), which have a pKa value of no greater than about 4, have the ability to generate a cationic charge in itself when dispersed in an aqueous solution, provided that the pH of the final composition does not is greater than about 6. The counter ion X "(IX) can be chloride, bromide, methylisulfate, formate, sulfate, nitrate and mixtures thereof In fact, the anion X" is only found P1439 -.1 .--- S -t-l-á-jU-Hi .- .. _, _ «« _ .. present as a counter-ion of the quaternary ammonium compounds positively charged. The scope of the present invention is not supposed to be limited to any particular anion. (f) dicuaternary ammonium compounds according to the general formula (X), (XI), (XII) or (XIII): 2X (X) (XI) (XII P1439 t-l-- -i. Í? & '?? L * - * "-" - •' --- »---. - -to"-*. ----- ^ i'l * i 2X (XIII) wherein R5, R6, Q, n & X "are as defined above in this invention when referring to general formula (II) and (III), Ri3 is selected from alkylene groups (C? -C6), preferably an ethylene group, z is a number from 0 to 4. (g) mixtures of the above quaternary ammonium compounds The preferred quaternary ammonium agents that are used in the present invention are those described in section (b) shown above in this invention. the diester and / or quaternary ammonium diamide compounds (DEQA) according to the general formula (II) shown above in this invention.The preferred diesters which are used in this invention are those according to the general formula (II), wherein R5, R6 and X " P1439 they are as defined above in this invention and Q is: -O- c- Preferred diamides to be used in this invention are those according to the general formula (II), wherein R5, R6 and X "are as defined above in this invention and Q is: H O I II -N-C- Preferred examples of suitable quaternary ammonium compounds which are used in the compositions of the present invention are N, N-di (canolyl-oxy-ethyl) -N, N-dimethyl ammonium chloride, N, N-di (canolyl-oxy) ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methylisulfate, N, N- di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium chloride and mixtures thereof same. In particular, N, N-di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methylisulfate is preferred for use in this invention. Although quaternary ammonium compounds are derived from fatty acyl groups "canolyl" are preferred, P1439 / "- < ^ 21 other suitable examples of quaternary ammonium compounds are derived from fatty acyl groups, wherein the term "canolyl" of the above examples is replaced by the terms "seboyl, cocoyl, palmyl, lauryl, oleyl, ricinoleyl, stearyl, palmityl" which correspond to the triglyceride source from which the fatty acyl units are derived. These alternative sources of fatty acyl can comprise chains either completely saturated or, preferably, at least partially unsaturated.

Sunscreen A second essential element of the compositions of the present invention is that they comprise at least one 15 active ingredient of sunscreen. These sunscreen active ingredients include both organic compounds and their salts, as well as inorganic particle materials. Without being limited by theory, it is thought that sunscreen agents provide protection against 20 ultraviolet radiation by means of one or more of the following mechanisms including absorption, screen and reflection of ultraviolet radiation. Non-limiting examples of these sunscreen agents are described in U.S. Pat. No. 25 5,087,445, for Haffey et al., Filed on 11 P1439 February 1992; U.S. Patent No. 5,073,372, to Turner et al., Filed December 17, 1991; U.S. Patent No. 5,073,371, to Turner et al. Filed December 17, 1991; U.S. Patent No. 5,160,731, to Sabatelli et al., Filed on November 3, 1992; U.S. Patent No. 5,138,089, to Sabatelli, filed on August 11, 1992; U.S. Patent No. 5,041,282, to Sabatelli, filed August 20, 1991; U.S. Patent No. 4,999,186, to Sabatelli et al., Filed March 12, 1991; U.S. Patent No. 4,937,370, to Sabatelli, filed June 26, 1990; and Segarin et al., in Chapter VIII, pages 189 et seq., of Cosmetics Science and Technology. Preferred sunscreen agents include those selected from the group consisting of 2-ethylhexyl p-methoxycinnamate, octyl salicylate, octocrylene, oxybenzone, 2-ethylhexyl N, N-dimethyl aminobenzoate, p-aminobenzoic acid, 2-ethylhexyl acid, -phenyl-benzimidazole-5-sulfonic acid, homomenthyl salicylate, DEA p-methoxycinnamate, 4,4'-methoxy-t-butyl dibenzoylmethane, 4-isopropyl dibenzoylmethane, 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor, ester of 4-N, N- acid P1439 ¿Á ¿i &.É1 * & .lt., - »• ------- ----- Ua -------------- dimethylaminobenzoic acid with 2,4-dihydroxybenzophenone, 4-N acid ester, N-dimethylaminobenzoic acid with 2-hydroxy-4- (2-hydroxyethoxy) benzophenone, 4-N, N-dimethylaminobenzoic acid ester with 4-hydroxydobenzoyl-methane, 4-N, N-dimethylaminobenzoic acid ester with 4- (2- hydroxyethoxy) dibenzoylmethane, 4-N, N-di (2-ethylhexyl) -aminobenzoic acid ester with 2,4-dihydroxybenzophenone, 4-N, N-di (2-ethylhexyl) aminobenzoic acid ester with 2-hydroxy-4 - (2-hydroxyethoxy) benzophenone, benzophenone ester, 4-N, N-di (2-ethylhexyl) aminobenzoic acid ester with 4-hydroxy dibenzoylmethane, 4-N, N-di (2-ethylhexyl) aminobenzoic acid ester with 4- (2-hydroxyethoxy) dibenzoylmethane, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 2,4-dihydroxybenzophenone, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 2 -hydroxy-4- (2-hydroxyethoxy) benzophenone, 4-N, N- (2-ethylhexyl) methyl ester aminobenzoic acid with 4-hydroxy dibenzoylmethane, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 4- (2-hydroxyethoxy) dibenzoylmethane, titanium dioxide, zinc oxide, iron oxide and mixtures thereof. More preferably, sunscreen agents selected from the group consisting of N, N-dimethyl-p-aminobenzoate 2-ethylhexyl, p-methoxycinnamate 2-ethylhexyl, octocrylene, octyl salicylate are used in the compositions described in this invention. , P1439 homomenthyl salicylate, p-aminobenzoic acid, oxybenzone, 2-phenylbenzimidazole-5-sulfonic acid, DEA p-methoxycinnamate, 4,4'-methoxy-t-butyldibenzoyl methane, 4-isopropyl dibenzoyl methane, 3- (4-methylbenzylidene) ) camphor, 3-benzylidene camphor, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 4- (2-hydroxyethoxy) dibenzoyl methane, titanium dioxide, zinc oxide, iron oxide and mixtures thereof . The exact amounts of sunscreen that can be used will vary depending on the chosen sunscreen and the desired Sun Protection Factor (SPF) that you want to achieve. FPS is a commonly used measure of the sun protection of a sunscreen against erythema. See Federal Register, Vol. 43, No. 166, pp. 38206-38269, August 25, 1978. However, preferably the compositions of the present invention comprise from 0.01% to 20%, more preferably from 0.1% to 10% by weight, of active ingredient of sunscreen.

Optional Ingredients The compositions of the present invention may contain a variety of optional components suitable for administering the present compositions in a more cosmetically or aesthetically acceptable form, or provide additional benefits to the treatment. This P1439 class of conventional optional ingredients are well known to those who dominate the technical field. These include any cosmetically acceptable ingredient, such as, for example, those ingredients found in the CTFA International Cosmetic Ingredient Dictionary and Handbook, the edition, edited by Wenninger and McEwen, (The Cosmetic, Toiletry, and Fragrance Association, Inc., Washington , D. C, 1997). Some non-limiting examples of this class of optional ingredients are provided below.

Skin Care Agents It is highly preferred that the compositions of the present invention comprise a skin care agent. As used in this invention, the term "skin care agent" means any compound or mixture of compounds that, for example, provides hydration, protection, pleasant skin feel, benefits of softness and / or smoothness of the skin. skin. Preferred skin care agents that are used in the present invention are humectants, emollients and mixtures thereof. Preferably, the compositions of the present invention comprise humectants and emollients. Preferably, the compositions of the present P1439 ? Á? -? SS: ñ. ^ Á fes-fc- -. ll "l & & t < t & 2 & amp; & amp; & & & & invention comprise at least 1% by weight of the skin care agent. More preferably, the present compositions comprise from 2% to 70%, preferably 5% to 60%, even more preferably 10% to 55%, by weight of skin care agent.

Humectant A highly preferred optional ingredient for the compositions of the present invention is the humectant. As used in this invention, the term "humectant" means a substance that provides the skin with the benefits of water retention. Preferably, the compositions of the present invention comprise at least 1%, more preferably at least 5%, still more preferably at least 10%, still more preferably at least 20%, by weight of humectant . Any suitable humectant to be used in cosmetic compositions can be used in this invention. Non-limiting examples of suitable humectants which are used in the present invention are described in 098/22085, 098/18444 and 097/01326. Preferably, the humectants that are used in this invention are selected from the group consisting of, but not limited to; amino acids and derivatives P1439 thereof such as proline and arginine aspartate, 1,3-butylene glycol, propylene glycol and water and extract of codium tomentosu, amino acids or collagen peptides, creatinine, diglycerol, biosaccharide gum-1, glucamine salts, acid salts glucuronic, salts of glutamic acid, glycerin ethers of polyethylene glycol (for example, glycereth 20), glycerin, glycerol monopropoxylate, glycogen, hexylene glycol, honey and extracts or derivatives thereof, hydrogenated starch hydrolysates, hydrolysed mucopolysaccharides, inositol, amino acids of keratin, urea, LAREX A-200 (commercially available from Larex), glycosaminoglycans, methoxy PEG 10, methyl gluceth-10 and -20 (both commercially available from Amerchol, located in Edison, NJ), methyl glucose, 3-methyl- 1,3-butanediol, salts of N-acetyl glucosamine, polyethylene glycol and derivatives thereof (such as for example PEG 15 butanediol, PEG 4, PEG 5 pentaerythritol, PEG 6, PEG 8, PEG 9), pentaerit itol, 1,2-pentanediol, PPG-1 glyceryl ether, PPG-9, 2-pyrrolidone-5-carboxylic acid and its salts such as glyceryl pea, sucrose isomerate, SEACARE (commercially available in Secma), sericin, amino acids of silk, sodium acetylhyaluronate, sodium hyaluronate, sodium polyaspartate, sodium polyglutamate, sorbeth 20, sorbeth 6, sugar and sugar alcohols and derivatives thereof such as glucose, mannose P1439 b? l * .J.á. < . - .- | mÜH --- - * - * • --- * -. "» .. ,, .. _ "_. --.-- "... -.- i» - »-. -Y--*,". Í.1..I-. and polyglycerol sorbitol, trehalose, triglycerol, trimethylolpropane, tris (hydroxymethyl) amino methane salts and yeast extract and mixtures thereof. More preferably, the humectants used in this invention are selected from the group consisting of glycerin, urea, butylene glycol, polyethylene glycol and derivatives thereof, or mixtures thereof. Even more preferably, the humectants that are used in this invention are selected from the group consisting of glycerin, urea and mixtures thereof, especially glycerin.

Emollients Another highly preferred optional ingredient of the compositions of the present invention is the emollient.

Emollients tend to lubricate the skin, increase the softness and flexibility of the skin, prevent or alleviate the dryness of the skin, and / or protect the skin. A wide variety of suitable emollients are known and can be used in this invention. Sagarin, Cosmetics, Science and Technology, 2nd Edition, Vol. l, pp. 32-43 (1972) contains numerous examples of suitable materials that are used as emollients. Preferably, the compositions of the present invention comprise more than 1%, more preferably at least 5%, even with greater P1439 L - Í.LÍ preference for at least 10%, by weight, of emollient. Preferably, the emollients used in this invention are selected from the group consisting of: i) Linear or branched hydrocarbon chains with from about 7 to about 40 carbon atoms, such as, for example, dodecane, squalane, petrolatum, cholesterol and derivatives thereof, hydrogenated polyisobutylene, isohexadecane and the C7-C40 isoparaffins, which are branched C7-C40 hydrocarbons, ii) C? -C30 alcohol esters of C? -C30 carboxylic acids and C2-C30 dicarboxylic acids, for example isononyl isononanoate, isopropyl myristate, myristyl propionate, isopropyl stearate, behenyl behenate, dioctyl maleate, isopropyl adipate and diisopropyl dilinoleate. iii) mono, di and triglycerides of C?-C 30 carboxylic acids and the ethoxylated derivatives thereof. Suitable polyethylene glycol derivatives of glycerides include PEG-20 glycerides of almonds, PEG-60 glycerides of almonds, PEG-11 glycerides of avocado, PEG-6 capric / caprylic glycerides, PEG-20 corn glycerides, PEG-60 corn glycerides. , glycerides PEG-60 evening primrose oil, glyceryl cocoate PEG- P1439 -j .6 a ¡_ .. X & > .. £ .... sm .. * - cf .j? * -,, .- te «-, ^. Ftl 7, glyceryl cocoate PEG-30, glyceryl cocoate PEG-40, glyceryl cocoate PEG- 78, glyceryl cocoate PEG-80, glyceryl dioleate PEG-12, glyceryl isostearate PEG-15, glyceryl isostearate PEG-20, glyceryl isostearate PEG-30, PEG-75 glycerides of cocoa butter, PEG-20 glycerides of hydrogenated palm oil, PEG-70 mango glycerides, PEG-13 mink glycerides, PEG-75 glycerides of fruit butter from Shorea Robusta, PEG-10 olive glycerides, glycerides PEG-12 palm nut, PEG-45 palm nut glycerides, PEG-8 glyceryl laurate and PEG-30 glyceryl laurate. Mixtures of polyethylene glycol glyceride derivatives can also be used in this invention. iv) alkylene glycol esters of C -C 30 carboxylic acids, for example mono and di-esters of ethylene glycol and mono- and di-esters of propylene glycol of C? -C30 carboxylic acids, for example ethylene glycol distearate. v) Organopolysiloxane oils. The organopolysiloxane oil can be volatile, non-volatile or a mixture of volatile and non-volatile silicones. The term "non-volatile", as used in this context, refers to those silicones that are P1439 liquids under ambient conditions and having an ignition point (under conditions of a pressure atmosphere) of or greater than about 100 ° C. The term "volatile", as used in this context refers to all other silicone oils. Suitable organopolysiloxanes can be selected from a wide variety of silicones that reach a wide range of volatilities and viscosities. Non-volatile polysiloxanes are preferred. Suitable silicones are disclosed in U.S. Patent No. 5,069,897, filed December 3, 1991. Preferred organopolysiloxanes which are used in this invention are selected from the group consisting of polyalkylsiloxanes, dimethicones with alkyl substitution, dimethiconols, polyalkylaryl siloxanes and mixtures thereof. More preferred for use in this invention are polyalkylsiloxanes and cyclomethicones. Preferred among the polyalkylsiloxanes are the dimethicones. Vegetable oils and hydrogenated vegetable oils.

Examples of vegetable oils and hydrogenated vegetable oils include safflower oil, castor oil, coconut oil, cottonseed oil, - ---- ... % fc. --and ---.- ~ .__ a-fci-iii-ifc_.a-at _. »- .. ^ t _. _ > . . . _. -__. » .. _. -.- &, .- t i. shad oil, palm kernel oil, palm oil, peanut oil, soybean oil, rape seed oil, flaxseed oil, rice bran oil, pine oil, sesame oil, oil 5 sunflower seed, partially and totally hydrogenated oils from the above sources and mixtures thereof, vii) animal fats and oils, for example cod liver oil, lanolin and its derivatives such as acetylated lanolin and isopropyl lanolate. The lanolin oil is preferred, viii) Also useful are the C4-C20 alkyl ethers of polypropylene glycol, propylene glycol esters of C? -C2o carboxylic acid and di-C8-C30 alkyl ethers, examples including PPG-14 butyl ether, PPG-15 stearyl ether, dioctyl ether, dodecyl octyl ether and mixtures thereof, ix) polyol carboxylic acid esters. ix) polyol carboxylic acid esters. 0 x) mixtures of the above. Preferred emollients which are used in the compositions of this invention are selected from the group comprising dodecane, squalane, cholesterol and derivatives thereof, isohexadecane, isononyl isononanoate, petrolatum, lanolin and its derivatives, safflower oil, Pl 39 castor oil, coconut oil, cottonseed oil, palm kernel oil, palm oil, peanut oil, soybean oil, polyol carboxylic acid esters and mixtures thereof. The most preferred emollients that are used in this invention are selected from polyol carboxylic acid esters, petrolatum and mixtures thereof. These esters are derived from a sugar or from a polyol fraction and from one or more carboxylic acid moieties. Depending on the acid constituent and the sugar, these esters can be found in either liquid or solid form at room temperature. Examples of liquid esters include: glucose tetraoleate, the glucose tetraesters of the fatty acids of soybean oil (unsaturated), the tetraesters of mixed fatty acid mannoses of soybean oil, the tetraesters of galactose of oleic acid, the tetraesters of arabinose of linoleic acid, xylose tetralmoleate, galactose pentaoleate, sorbitol tetraoleate, sorbitol hexaesters of unsaturated soybean oil fatty acids, xylitol pentaoleate, sucrose tetraoleate, sucrose pentaolate, sucrose hexaoleate, sucrose hepatoleate, sucrose octaoleate and mixtures thereof. Examples of solid esters include: sorbitol hexaester in which P1439 Fractions of the carboxylic acid ester are palmitoleate and arachididate in a 1: 2 molar ratio; the octaester of raffinose in which the carboxylic acid ester moieties are linoleate and behenate in a 1: 3 molar ratio; the maltose heptaester, wherein the esterifying carboxylic acid moieties are sunflower seed oil fatty acids and lignocerate in a 3: 4 molar ratio; the octaester of sucrose wherein the esterifying carboxylic acid moieties are oleate and behenate in a 2: 6 molar ratio; and the octaester of sucrose, wherein the esterifying carboxylic acid moieties are laurate, linoleate and behenate in a 1: 3: 4 molar ratio. A preferred solid material is the sucrose polyester in which the degree of esterification is 7-8 and in which the fatty acid moieties are C ?8 mono- and / or di-unsaturated and behenic, in a molar ratio of unsaturated : behenic from 1: 7 to 3: 5. A particularly preferred solid sugar polyester is the octaester of sucrose in which there are approximately 7 fractions of behenic fatty acid and about 1 oleic acid fraction in the molecule. Other materials include sucrose fatty acid esters of cottonseed oil or soybean oil. Ester materials are extensively described in, U.S. Patent No. 2, 831, 854, U.S. Patent No. 4,005,196, P1439 -_--; -. . »I. i it .fcb. tii J ... a jm »--- * Jl8; -b -. m_-?". - _.__, - «._. . ^ »" .__. A-a-tll- ..JÉ for Jandacek, presented on January 25, 1977; U.S. Patent No. 4,005,195, to Jandacek, filed January 25, 1977, U.S. Patent No. 5,306,516, to Letton et al., Filed April 26, 1994; U.S. Patent No. 5,306,515, to Letton et al., Filed April 26, 1994; U.S. Patent No. 5,305,514, to Letton et al., Filed April 26, 1994; U.S. Patent No. 4,797,300, to Jandacek et al., Filed January 10, 1989; U.S. Patent No. 3,963,699, to Rizzi et al., Filed June 15, 1976; U.S. Patent No. 4,518,772, to Volpenhein, filed May 21, 1985; and U.S. Patent No. 4,517,360, to Volpenhein, filed May 21, 1985. Suitable polyolesters of polyol fatty acids used in this invention can be prepared by a variety of well-known methods for those who master the technical field. These methods include: transesterification of the polyol with fatty acid esters of methyl, ethyl or glycerol using a variety of catalysts; acylation of the polyol with a fatty acid chloride; polyol acylation P1439 ? í.4"á .. t .i. ± **. ? - -. i .. - -a-j.- .. --- i. - «f -yjrá r? ftrt-r-t • - • - - • • • • • - • • - - --- ... with a fatty acid anhydride; and acylating the polyol with a fatty acid per se. See, for example, U.S. Patent No. 2,831,854; U.S. Patent No. 4,005,196, to Jandacek, filed January 25, 1977. A particularly preferred material is known by the INCI name of "sacarose policottonseedate", which is an ester of fatty acids of cottonseed oil and saccharose.

Other Skin Care Agents Other skin care agents may be useful in the compositions of the present invention.

Examples of other skin care agents that can be used in the present compositions include: (a) Vi tamine compounds The present compositions may comprise vitamin compounds, precursors and derivatives thereof. These vitamin compounds can be found either naturally or synthetically. Suitable vitamin compounds include, Vitamin A compounds (eg, beta carotene, retinoic acid, retinol, retinoids, retinyl palmitate, retinyl proprionate, etc.), P1439 .-, _, _....- i.

Vitamin B (for example, niacin, niacinamide, riboflavin, pantothenic acid, etc.), Vitamin C (for example, ascorbic acid, etc.), Vitamin D (for example, ergosterol, ergocalciferol, cholecalciferol, etc.), Vitamin E (for example, tocopherol acetate, etc.) and Vitamin K (for example, phytonadione, menadione, phthiocol, etc.). The preferred vitamin compounds that are used in the compositions of the present invention are the compounds of vitamin B3. The Vitamin B3 compounds are particularly useful for regulating the condition of the skin as described in O-A-97/39733. When present, the compositions of the present invention preferably comprise from about 0.01% to about 50%, more preferably from about 0.1% to about 10%, even more preferably from about 0.5% to about 5%, by weight , of the vitamin B3 compound. As used in this invention, "vitamin B3 compound" means a compound having the following formula: 1 wherein R is -CONH2 (for example, niacinamide), -COOH (by P1439 S ^ -. £, .. -. A .s .. -.- example, nicotinic acid) or -CH20H (for example, nicotinyl alcohol); and the derivatives thereof; and the salts of any of the above. Exemplary derivatives of the above vitamin B3 compounds include nicotinic acid esters, including non-vasodilating esters of nicotinic acid, nicotinyl amino acids, nicotinyl alcohol esters of carboxylic acids, N-oxides of nicotinic acid and N-oxides of niacinamide. Examples of suitable vitamin B3 compounds are well known in the technical field and are commercially available from various sources, for example, Sigma Chemical Company (St. Louis, MO); ICN Biomedicals, Inc. (Irvin, CA) and Aldrich Chemical Company (Milwaukee, Wl). The vitamin compounds may be included as the pure material substantially or as an extract obtained by means of physical and / or chemical isolation suitable from natural sources (for example, plants). (b) Active anti-wrinkle and anti-aging ingredients of the skin Examples of anti-wrinkle and anti-aging active ingredients of the skin that can be used in P1439 , .tl .... to tA ífci-ai ---. . ?? »*. *. . .- • * - t? "H» _-- & . compositions of the present invention including, but not limited to, lactic acid and derivatives - «i -je] _0 m_sm? / Retinoic acid and its derivatives (eg, cis and trans); retinol; retinyl esters; niacinamide, 5 salicylic acid and derivatives thereof; D and L sulfur-containing amino acids and their derivatives and salts, particularly the N-acetyl derivatives, a preferred example of which is N-acetyl-L-cysteine; thiols, for example, ethanethiol; hydroxy acids, phytic acid, lipoic acid; lysophosphatidic acid and agents for exfoliating the skin (eg, phenol and the like). (c) Antimicrobial and antifungal active ingredients Examples of antimicrobial active ingredients 5 and antifungals that can be used in the compositions of the present invention including, but not limited to, R-lactam drugs, quinolone drugs, ciprofloxacin , norfloxacin, tetracycline, erythromycin, amikacin, 2, 4, 4 '-trichloro-2' -0 hydroxy diphenyl ether, 3,4,4'-trichlorocarbanilide, phenoxyethanol, phenoxypropanol, phenoxyisopropanol, doxycycline, capreomycin, chlorhexidine, chlortetracycline, oxytetracycline , clindamycin, ethambutol, hexamidine isethionate, metronidazole, pentamidine, gentamicin, 5 kanamycin, lineomycin, metacycline, methenamine, P1439 - ^^^ '- A? F ^ ?. I Minocycline, neomycin, netilmicin, paromomycin, streptomycin, tobramycin, miconazole, tetracycline hydrochloride, erythromycin, zinc erythromycin, erythromycin estolate, erythromycin stearate, amikacin sulfate, doxycycline hydrochloride, capreomycin sulfate, chlorhexidine gluconate, hydrochloride of chlorhexidine, chlortetracycline hydrochloride, oxytetracycline hydrochloride, clindamycin hydrochloride, ethambutol hydrochloride, metronidazole hydrochloride, pentamidine hydrochloride, gentamicin sulfate, kanamycin sulfate, lineomycin hydrochloride, methacycline hydrochloride, methenamine hippurate, methenamine mandelate Minocycline hydrochloride, neomycin sulfate, netilmicin sulfate, paromomycin sulfate, streptomycin sulfate, tobramycin sulfate, miconazole hydrochloride, amanfadine hydrochloride, amanfadine sulfate, octopyroxine, parachloro metaxylenol, nystatin, tolnaftate, zinc pyrithione and Clotrimazole Polar Solvent The compositions of the present invention may also comprise polar solvents. Any polar solvent suitable for use in cosmetic compositions can be used in this invention. However, the polar solvent must be sufficiently P143.9 --i ...- -._ .. * .. < -.? _-, .., * at -? - 1 »» - • .-.,. jc-Maf .- .., ..... ............ -? Aj fatA: polar to stimulate the formation of vesicles in the present invention. Preferably, the polar solvent used in the compositions of the present invention is water. The present compositions preferably comprise from 10% to 90%, more preferably from 20% to 80%, even more preferably from 30% to 60%, by weight, of polar solvent.

Thickeners The compositions of the present invention, preferably, comprise thickeners. Any suitable thickener to be used in cosmetic compositions can be used in this invention. Preferred thickeners are selected from water-soluble nonionic polymers, fatty alcohols and mixtures thereof. Suitable nonionic polymers include water-soluble polymers such as cellulose ethers (for example hydroxybutyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl methyl cellulose, ethylhydroxyethyl cellulose, hydrophobically modified hydroxyethyl cellulose and hydroxyethyl cellulose), poly (ethylene oxide) , polyvinyl alcohol, polyvinyl pyrrolidone, hydroxypropyl guar gum, amulose, hydroxyethyl amylose, starch and starch derivatives. The suitable fatty alcohols are alcohols P143- 9 Üte 'J-. IÍ - 1. Í tfcJSJ.f », ... .IJMI-Mdil! * - .. *!» ». * I,: -,,. , .__. .. -. . ... i. ...._ > -JB-MUlt »-. , _-.-. .. .--TO,."..-. ,. ..? _ *. .fel- * high molecular weight, non-volatile primary, which have the general formula RCH2OH wherein R is a (C8-C2o) alkyl • They can be produced from natural fats or oils by reducing the COOH grouping of the fatty acid to the hydroxyl function. Alternatively, identical fatty alcohols or alcohols of similar structure can be produced according to conventional synthesis methods known in the technical field. Suitable fatty alcohols include, but are not limited to, behenylalcohol, C9-Cu alcohols, C12-C3 alcohols, C2-C5 alcohols, C2-C6 alcohols, C6-C5 alcohols, alcohol. caprylic, cetearyl alcohol, coconut alcohol, decyl alcohol, isocetyl alcohol, isostearyl alcohol, lauryl alcohol, oleyl alcohol, palm kernel alcohol, stearyl alcohol, cetyl alcohol, beef tallow alcohol, tridecyl alcohol or myristyl alcohol.

Other optional ingredients The compositions of the present invention may comprise a wide range of other optional components. These additional components must be pharmaceutically P1439 _fc_J ..-. A. *. -_ _ _ ... fc. . .. ^. fc ..--. ....TO . -. • - .. acceptable Examples including, but not limited to, functional classes of suitable ingredients that are used in the compositions of the present invention: abrasives, absorbers, anti-acne active ingredients, anti-caking agents, anti-dandruff agents, antiperspirant agents, antioxidants, antiviral active ingredients , active ingredients and accelerators for artificial tanning, biological additives, bleaches, bleach activators, brighteners, builders, pH buffering agents, chelating agents, chemical additives, dyes, cosmetics, cleansers, cosmetic astringents, cosmetic biocides, denaturants, deodorants, ingredients active ingredients for desquamation, epilators, astringent drugs, dyes, dye transfer agents, enzymes, external analgesics, foam generators, flavorings, film formers, fragrance components, insect repellents, fungicides, active ingredients anti-inflammatory agents, opacifying agents, oxidant dyes, oxidizing agents, ingredients for pest control, pH adjusters such as citric acid, pH buffer solutions, pharmaceutical active ingredients, plasticizers, preservatives, radical containers, bleaching agents skin, hair or nails, conditioners for skin, hair or nails, P1439 - "> ..; «. T_tJ • --- *» penetration enhancers for skin, hair or nails, stabilizers, surfactants, surface conditioners, reducing agents, temperature depressants, viscosity modifiers and heat generators such as exothermic zeolites . Also useful in this invention are the aesthetic components such as colorants, essential oils and skin repairing agents. Other optional materials of this invention include pigments. Suitable pigments that are used in the compositions of the present invention can be organic or inorganic. Also included within the term pigment, are materials that have a low color or luster such as agents for matte finish and also agents that provide a screen to light. Examples of suitable pigments are iron oxides, iron oxides, aciglutamate, titanium dioxide, ultramarine blue, D & C, carmine and mixtures thereof.

Formulation Processes Preferably, the compositions of the present invention are prepared in such a way that the quaternary ammonium compounds form vesicles. It is preferable that the vesicles also comprise a humectant. Preferably the vesicles also comprise an emollient. Even more preferred, the vesicles comprise active ingredients of sunscreen. In order to ensure optimum performance characteristics, it is preferred that the compositions of the present invention be prepared in the following manner: (i) all or part of the quaternary ammonium agent is mixed with a humectant, sunscreen active ingredients soluble in water, water-soluble skin care active ingredients (where included) and preferably a polar solvent at a temperature higher than the melting point of the quaternary ammonium agent; (ii) optionally, the mixture is stirred vigorously; (iii) the emulsion is prepared in a separate vessel in the following manner; the oil phase containing the emollients, the relevant thickener in case the thickener is soluble in oil, the active ingredients of the oil-soluble sunscreen and any remaining quaternary ammonium agent are mixed together at a temperature higher than the point of fusion of the quaternary ammonium agent; The aqueous phase is prepared separately. The water, the relevant thickener, in case the thickener is soluble in water and the remaining water-soluble ingredients are heated to the same temperature at the same time.

P1439 that is the oil phase. (iv) the temperature of the oil and aqueous phases of the emulsion are approximately equal and the aqueous phase is combined with the oil phase by means of stirring. (v) On the production of the emulsion, the mixture formed in step (i) is added to the aforesaid emulsion with stirring.

Methods of Use The cosmetic compositions of the present invention can be used in a conventional manner for the treatment of the skin. An effective amount of the composition, typically from about 0.1 grams to about 50 grams, preferably from about 1 gram to about 20 grams, is applied to wet or dry, preferably wet, skin. Application of the composition typically includes working the composition on the skin, usually with the hands and fingers. The composition is then left on the skin or, preferably, the skin is rinsed. The preferred method for treating the skin, therefore, comprises the steps of: (a) applying an effective amount of the cosmetic composition on the skin, P1439 -. £ .1 * 1. -i * -. »-. t? AíJf. t. (b) rinsing the skin. A preferred aspect of the present invention involves the above method with an application of the composition on dry skin before application on wet skin. Accordingly, a preferred method comprises: (i) application to the dry skin of an effective amount of the cosmetic composition; (ii) rinsing the skin under a shower; (iii) an additional application of the composition; and (iv) an additional rinse. Much of the deterioration to human skin is caused by repeated exposure to compositions containing surfactants during the washing routine. It has been found that this deterioration can be mitigated using the present compositions. Therefore, another preferred method comprises: (i) skin washing using a composition comprising surfactants; (ii) skin rinsing; (iii) application to the wet skin of a composition according to the present invention; (iv) rinsing the skin. It has also been found that the compositions P1439 the i.¡--; .i.i ..? ...? _ & _ z -a. . ?? These are particularly useful when incorporated as part of a regular routine. Accordingly, another preferred method comprises: (i) applying to the skin a composition comprising: (a) at least one quaternary ammonium compound; (b) a humectant; and (ii) rinsing the skin; 10 (iii) repetition of steps (i) and (ii) within a 48-hour period. The present compositions may also be useful for mitigating the deterioration caused by exposure of the skin to ultraviolet radiation, the 15 deterioration caused by exposure of the skin to water during swimming or exercises based on similar water, deterioration caused by shaving or exfoliation or deterioration caused by exposure of the skin to water during the daily bath. EXAMPLES The following examples further illustrate the preferred embodiments within the scope of the present invention. The examples are provided only with the 25 purpose of illustrating and should not be construed as P1439 limitations of the present invention since a variety of variations of the invention are possible without departing from its spirit or scope. Unless indicated otherwise, all ingredients are expressed as a percentage by weight of the active ingredient.

P1439 i > Í ¿S? ACE? .fci i • P1439 ».",? and. ? Í .. ít.;., "* _". "., _" ... ii tí.-¿^ .-- ea *. a, ^ _ > --- *. * P1439 Í.ffí.? A? * AFÍBÁi .. f.i..f._. f-'f ^ - • P1439 ...... £ .i íí.í.-ít i- 1; Commercially available in Croda 2; Commercially available at Floratech, AZ, USA 3; Commercially available at Hoffman La Roche, NJ, USA 4; Commercially available in Amerchol, NJ, USA P1439 t r & ii-.á? : Í: -. ,, __- B, •? -i i..a 5; Commercially available in Rhodia, NJ, USA • In Examples 1, 4, 7, 9, 17, 20, 22, 24, 28, 36, 38, 47, 49, 53, 56 the quaternary ammonium compound used is chloride distearyl dimethyl ammonium supplied by Goldschmidt, trade name Varisoft TA100. • In examples 2, 3, 5, 6, 8, 10, 15, 16, 18, 19, 21, 23, 26, 27, 31, 33, 34, 35, 37, 41, 45, 46, 48, 50, 51, 52, 54, 55 the quaternary ammonium compounds used are N, N-di (canolyl-oxy-ethyl) -N methyl, N- (2-hydroxyethyl) ammonium sulfate supplied by Goldschmidt, trade name Rewoquat V3620. • In Example 11 the quaternary ammonium compound used is N, N-di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium sulfate supplied by Goldschmidt, trade name Rewoquat E18. • In Example 12 the quaternary ammonium compound used is N, N-di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium chloride, supplied by Goldschmidt, development material (E25). • In Example 13 the quaternary ammonium compound used is methylbis (hydrogenated tallowamidoethyl) (2-hydroxyethyl) ammonium sulfate supplied by Goldschmidt, trade name Varisoft 110. • In Example 14 the quaternary ammonium compound P1439 ÍX j A X.? .? ílkÍ, í > r .. i? ...,. ..-,. i. . I ^ J,,. Í.Í .. -. "I .. used .- is methylbis (tallowamidoethyl) (2-hydroxyethyl) ammonium methyl sulfate supplied by Goldschmidt, trade name Varisoft 222. • In the example 25 the quaternary ammonium compound used is methyl-l-tallowylethyl-2-seboimidazoline supplied by Goldschmidt, development material • In Example 29 the quaternary ammonium compound used is methyl-l-tallowamidoethyl-2-seboimidazoline supplied by Goldschmidt, development material • In Example 30 the The quaternary ammonium compound used is methyl-l-tallowylethyl-2-seboimidazolinium methyl sulfate supplied by Goldschmidt, • In Example 32 the quaternary ammonium compound used is methyl-l-tallowamidoethyl-2-seboimidazolinium methyl sulfate supplied by Goldschmidt, trade name Varisoft 475, Varisoft 445 • In example 39 the quaternary ammonium compound used is N, N-dimethyl-N- (canolyl-oxy-ethyl) -N- (canolamidoethyl) amine, supplied by Kao . • In Example 40 the quaternary ammonium compound used is N, N-dimethyl-N- (canolyl-oxy-ethyl) -N- (canolamidoethyl) ammonium sulfate methyl, supplied by Kao. • In Example 42 the quaternary ammonium compound used is N, N '-bis (2-tallowoyloxyethyl) -N, N, N', N "- P1439 tetramethylene diammonium dichloride, as disclosed in U.S. Patents US4728337, US 4721512, US 4906413 of Ciba-Geigy Corporation. • In Example 43 the quaternary ammonium compound used is N, N'-bis (2-canolyloxyethyl) -N, N'-dimethyl-N, N'- (2-hydroxyethyl) -1,6-hexan dimethyl sulfate. ammonium, as disclosed in EP 0503155A1 & EP 0803498 from Goldschmidt -Witco. • In Example 44 the quaternary ammonium compound used is the di and oligo ester quat made by the reaction of the fatty acid, difunctional (or multifunctional) acid and triethanolamine followed by quaternization as revealed in W098 / 49132 by Kao and in U.S. Patent 5880289 by Henkel.

Process For those examples that include component C: 1. Premix 1: Combine the components of group A together, at a temperature higher than the transition temperature of the chosen quaternary ammonium compound, keeping behind a predetermined part of the quaternary ammonium compound and water. Shake this premix vigorously. 2. Premix 2: Combine the components of groups B and C with the remaining parts of the compounds of P1439 . i i.

Quaternary ammonium and water not previously used in premix 1. Heat above the melting point of quat and oils. 3. Combine premixes 1 & 2 and allow it to cool to a temperature of 40 ° C, stir in the perfume.

For those examples that include component D: 1. Premix 1: Combine the components of group A together, at a temperature higher than the transition temperature of the quaternary ammonium compound, keeping behind a predetermined part of water. Shake this premix vigorously. 2. Premix 2: Combine with agitation the components of group D with water that was not previously used in premix 1. 3. Combine premixes 1 & 2 and the components of the B & amp; E. Shake vigorously. The compositions of the previous examples provide the benefits of good skin care, such as good wetting, good hydration, pleasant skin feeling, marked softness and / or smoothness of the skin, with low levels of effects negative such as greasy feeling, sticky feeling or adhesion.

P1439

Claims (10)

1. CLAIMS; A cosmetic composition comprising: (a) at least one quaternary ammonium agent; and (b) at least one active ingredient of a sunscreen. 2. A composition according to claim 1, wherein the composition further comprises a skin care agent. 3. A composition according to any preceding claim, wherein the composition further comprises a skin care agent selected from the group consisting of humectant, emollient and mixtures thereof. A composition according to any preceding claim, wherein the active ingredient is selected from the group consisting of N, N-dimethyl-p-aminobenzoate 2-ethylhexyl, p-methoxycinnamate 2-ethylhexyl, octocrylene, octyl salicylate, salicylate of homomenthyl, p-aminobenzoic acid, oxybenzone, 2-phenylbenzimidazole-5-sulfonic acid, DEA p-methoxycinnamate, 4,4'-methoxy-t-butyldibenzoyl methane, 4-isopropyl dibenzoyl methane, 3- (4-methylbenzylidene) camphor, 3-benzylidene camphor, 4-N, N- (2-ethylhexyl) methylaminobenzoic acid ester with 4- (2-hydroxyethoxy) dibenzoyl methane, P1439 * titanium dioxide, zinc oxide, iron oxide and mixtures thereof. 5. A composition according to any of the preceding claims, wherein the composition 5 comprises from 0.01% to 20%, more preferably from 0.1% to 10% by weight of active ingredient of the sunscreen. 6. A composition according to any of the preceding claims, wherein the quaternary ammonium agent is selected from those having the formula 10 general (II) or (III): (R5) 4- m N + - ((CH2) n Q- R 6 Jm X "(ll) (R5) 4.r N + - (CH2) n- - 15 where, each R5 unit is selected independently of the group which is composed of hydrogen, straight or branched chain (C? -C6) alkyl, hydroxyalkyl (C? -C6) straight or branched chain and Mixtures thereof, preferably methyl and hydroxyethyl; each Rs unit is independently a linear or branched alkyl (Cn-C22), alkenyl (Cn-C22) P1439 Linear or branched, and mixtures thereof; X "is an anion that is compatible with the active ingredients for skin care and with the adjunct ingredients; m is a number from 1 to 4, preferably 2; n is a number from 1 to 4, preferably 2 and Q is a carbonyl unit selected from the group consisting of: -CO- O -O - c - o - R7 or -N-C- O R7 -C-N-, and wherein R7 is hydrogen, (C? -C4) alkyl, hydroxyalkyl (C1-? P1439 C4) and mixtures thereof. A composition according to any one of the preceding claims, wherein the quaternary ammonium agent is selected from N, N-di (canolyl-oxy-ethyl) -N, N-dimethyl ammonium chloride, N, N-di (canolyl) -oxi-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium methylisulfate, N, N- di (canolyl-oxy-ethyl) -N-methyl, N- (2-hydroxyethyl) ammonium chloride and mixtures thereof. 8. A composition according to any of the preceding claims, wherein the composition comprises vesicles, the vesicles comprising quaternary ammonium compounds together with a sunscreen ingredient. 9. A composition according to any of the preceding claims, wherein the composition comprises less than 5%, preferably less than 3%, preferably 0% by weight of an anionic surfactant. 10. The use of a composition according to any of the preceding claims for the treatment of the skin. P1439