MX9800537A - Moduladores de la funcion de receptores fas y otras proteinas. - Google Patents
Moduladores de la funcion de receptores fas y otras proteinas.Info
- Publication number
- MX9800537A MX9800537A MX9800537A MX9800537A MX9800537A MX 9800537 A MX9800537 A MX 9800537A MX 9800537 A MX9800537 A MX 9800537A MX 9800537 A MX9800537 A MX 9800537A MX 9800537 A MX9800537 A MX 9800537A
- Authority
- MX
- Mexico
- Prior art keywords
- receptor
- proteins
- modulators
- function
- fas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/641—Cysteine endopeptidases (3.4.22)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
- C12N9/6475—Interleukin 1-beta convertase-like enzymes (3.4.22.10; 3.4.22.36; 3.4.22.63)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Holo Graphy (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invencion provee proteínas capaces de modular o mediar el ligando de receptor FAS o el efecto TNF sobre células que llevan el receptor FAS o receptor p55 mediante union o interaccion con la proteína MORT-1, que a su vez, se une al dominio intracelular del receptor FAS o a otra proteína TRADD que se une al receptor p55; además, también se provee inhibidores de péptidos que interfieren con la actividad proteolítica de proteínas de union MORT-1 que tiene actividad proteolítica, así como un método para diseñarlas.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL11461595A IL114615A0 (en) | 1995-07-16 | 1995-07-16 | Modulators of the function of fas receptors and other proteins |
IL11498695A IL114986A0 (en) | 1995-08-17 | 1995-08-17 | Modulators of the function of fas receptors and other proteins |
IL11531995A IL115319A0 (en) | 1995-09-14 | 1995-09-14 | Modulators of the function of fas receptors and other proteins |
IL11658895A IL116588A0 (en) | 1995-12-27 | 1995-12-27 | Modulators of the function of fas receptors and other proteins |
IL11793296A IL117932A0 (en) | 1996-04-16 | 1996-04-16 | Modulators of the function of FAS receptors and other proteins |
PCT/US1996/010521 WO1997003998A1 (en) | 1995-07-16 | 1996-06-14 | Modulators of the function of fas receptors and other proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9800537A true MX9800537A (es) | 1998-05-31 |
Family
ID=27517674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9800537A MX9800537A (es) | 1995-07-16 | 1996-06-14 | Moduladores de la funcion de receptores fas y otras proteinas. |
Country Status (18)
Country | Link |
---|---|
US (3) | US6586571B1 (es) |
EP (2) | EP2042509B1 (es) |
JP (1) | JP3980641B2 (es) |
KR (1) | KR100491095B1 (es) |
CN (1) | CN100390195C (es) |
AT (1) | ATE431357T1 (es) |
AU (1) | AU708799B2 (es) |
CA (1) | CA2226973C (es) |
DE (1) | DE69637931D1 (es) |
DK (2) | DK2042509T3 (es) |
ES (2) | ES2326704T3 (es) |
HK (1) | HK1016990A1 (es) |
IL (1) | IL114615A0 (es) |
MX (1) | MX9800537A (es) |
NO (1) | NO321092B1 (es) |
PT (2) | PT914325E (es) |
SI (2) | SI2042509T1 (es) |
WO (1) | WO1997003998A1 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5712381A (en) * | 1994-10-19 | 1998-01-27 | Genetics Institute, Inc. | MADD, a TNF receptor death domain ligand protein |
US7097972B1 (en) | 1995-02-13 | 2006-08-29 | Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
US6060238A (en) * | 1995-02-13 | 2000-05-09 | The Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
US6015665A (en) * | 1995-02-13 | 2000-01-18 | The Regents Of The University Of Michigan | Method and composition for regulating apoptosis |
US6747138B1 (en) | 1995-04-03 | 2004-06-08 | Regents Of The University Of Michigan | Methods and compositions for regulating Fas-associated apoptosis |
US7807783B1 (en) | 1995-04-03 | 2010-10-05 | The Regents Of The University Of Michigan | Methods and compositions for regulating FAS-associated apoptosis |
US5976822A (en) * | 1995-05-18 | 1999-11-02 | Coulter International Corp. | Method and reagent for monitoring apoptosis and distinguishing apoptosis from necrosis |
US5712115A (en) * | 1996-03-19 | 1998-01-27 | Incyte Pharmaceuticals, Inc. | Human cell death-associated protein |
US5786173A (en) * | 1996-03-19 | 1998-07-28 | Idun Pharmaceuticals, Inc. | MCH4 and MCH5, apoptotic protease, nucleic acids encoding and methods of use |
US6008042A (en) * | 1996-05-16 | 1999-12-28 | Smithkline Beecham Corporation | Interleukin-1 beta converting enzyme like apoptotic protease-7 |
US5932694A (en) * | 1996-06-24 | 1999-08-03 | Ludwig Institute For Cancer Research | Nucleic acid molecule encoding a bifunctional protein, the protein so encoded and uses thereof |
EP0842665A3 (en) * | 1996-11-14 | 2002-12-18 | Smithkline Beecham Corporation | Interleukin-1 beta converting enzyme like apoptotic proteases and their agonists |
US5932425A (en) * | 1997-02-18 | 1999-08-03 | Signal Pharmaceuticals, Inc. | Compositions and methods for modulating cellular NF-κB activation |
US20040230039A1 (en) | 1997-03-01 | 2004-11-18 | Yeda Research And Development Co., Ltd. | Cash (caspase homologue) with death effector domain, modulators of the function of FAS receptors |
IL120759A0 (en) | 1997-03-03 | 1997-09-30 | Yeda Res & Dev | Modulators of the function of fas receptors and other proteins |
ATE238416T1 (de) * | 1997-06-27 | 2003-05-15 | Ono Pharmaceutical Co | Neue plasmid-dns, die ein reportergen enthält, und ihre verwendung. |
JPH1175859A (ja) * | 1997-09-08 | 1999-03-23 | R P R Jienseru Kk | アポト−シス関連遺伝子発現性のウイルスベクター系 |
EP1054991A1 (en) | 1998-02-11 | 2000-11-29 | Genvec, Inc. | Vectors, cells and methods for the production of deleterious viral eukaryotic gene transfer vectors |
US6207458B1 (en) * | 1998-05-07 | 2001-03-27 | University Of Washigton/Stowers Insitute For Medical Research | Proteins capable of regulating NF-κB JNK and apoptosis pathways and methods of using the same |
US6759041B1 (en) | 1998-05-29 | 2004-07-06 | Mochida Pharmaceutical Co., Ltd. | Preventives/remedies for autoimmune demyelinating diseases |
EP1100932A2 (en) | 1998-07-27 | 2001-05-23 | PHARMACIA & UPJOHN COMPANY | Method for autoactivation of procaspase 8 |
AU2222000A (en) * | 1998-12-31 | 2000-07-31 | St. Jude Children's Research Hospital | A tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein |
US7052834B1 (en) | 1998-12-31 | 2006-05-30 | St. Jude Children's Research Hospital | Tumor suppressor protein involved in death signaling, and diagnostics, therapeutics, and screening based on this protein |
WO2010006177A2 (en) * | 2008-07-10 | 2010-01-14 | Dana-Farber Cancer Institute, Inc. | Muc1, caspase-8,and ded-containing proteins |
Family Cites Families (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
US4737462A (en) | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
US4588585A (en) | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4518584A (en) | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
US4699880A (en) | 1984-09-25 | 1987-10-13 | Immunomedics, Inc. | Method of producing monoclonal anti-idiotype antibody |
US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
IL73883A (en) | 1984-12-20 | 1990-12-23 | Yeda Res & Dev | Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha |
US5116943A (en) | 1985-01-18 | 1992-05-26 | Cetus Corporation | Oxidation-resistant muteins of Il-2 and other protein |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4766067A (en) | 1985-05-31 | 1988-08-23 | President And Fellows Of Harvard College | Gene amplification |
EP0247091B1 (en) | 1985-11-01 | 1993-09-29 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
US5017691A (en) | 1986-07-03 | 1991-05-21 | Schering Corporation | Mammalian interleukin-4 |
GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US4879111A (en) | 1986-04-17 | 1989-11-07 | Cetus Corporation | Treatment of infections with lymphokines |
US4889818A (en) | 1986-08-22 | 1989-12-26 | Cetus Corporation | Purified thermostable enzyme |
US4795699A (en) | 1987-01-14 | 1989-01-03 | President And Fellows Of Harvard College | T7 DNA polymerase |
US4921794A (en) | 1987-01-14 | 1990-05-01 | President And Fellows Of Harvard College | T7 DNA polymerase |
IL83878A (en) | 1987-09-13 | 1995-07-31 | Yeda Res & Dev | Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it |
US4965195A (en) | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
US4904584A (en) | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
US5149782A (en) | 1988-08-19 | 1992-09-22 | Tanox Biosystems, Inc. | Molecular conjugates containing cell membrane-blending agents |
US5000000A (en) * | 1988-08-31 | 1991-03-19 | University Of Florida | Ethanol production by Escherichia coli strains co-expressing Zymomonas PDC and ADH genes |
IL94039A (en) | 1989-08-06 | 2006-09-05 | Yeda Res & Dev | Antibodies to tbp - 1 and their use |
US5142033A (en) | 1988-09-23 | 1992-08-25 | Hoffmann-La Roche Inc. | Structure-independent DNA amplification by the polymerase chain reaction |
US5091310A (en) | 1988-09-23 | 1992-02-25 | Cetus Corporation | Structure-independent dna amplification by the polymerase chain reaction |
US5066584A (en) | 1988-09-23 | 1991-11-19 | Cetus Corporation | Methods for generating single stranded dna by the polymerase chain reaction |
US4994370A (en) | 1989-01-03 | 1991-02-19 | The United States Of America As Represented By The Department Of Health And Human Services | DNA amplification technique |
US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
AU636608B2 (en) | 1989-05-18 | 1993-05-06 | Yeda Research And Development Co. Ltd. | Tumor necrosis factor binding protein II, it's purification and antibodies thereto |
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
IL101769A (en) | 1992-05-03 | 2007-02-11 | Yeda Res & Dev | Modulation of TNF receptor action |
IL104355A (en) | 1993-01-10 | 2006-08-20 | Yeda Res & Dev | Tnf receptor promoter |
IL109633A (en) | 1994-05-11 | 2005-05-17 | Yeda Res & Dev | Tnf receptor promoter |
IL111125A0 (en) | 1994-05-11 | 1994-12-29 | Yeda Res & Dev | Soluble oligomeric tnf/ngf super family ligand receptors and their use |
US6538121B1 (en) * | 1994-11-01 | 2003-03-25 | Human Genome Sciences, Inc. | Interleukin-1 β converting enzyme like apoptosis protease-3 and 4 |
CN1105725C (zh) * | 1994-12-15 | 2003-04-16 | 耶达研究与发展有限公司 | Fas/ap01受体功能的调节物 |
AU5133296A (en) * | 1995-02-22 | 1996-09-11 | Yeda Research And Development Co. Ltd. | Modulators of regulatory proteins |
ES2242195T3 (es) * | 1995-02-22 | 2005-11-01 | YEDA RESEARCH & DEVELOPMENT COMPANY, LTD. | Moduladores de proteinas reguladoras. |
US7807783B1 (en) * | 1995-04-03 | 2010-10-05 | The Regents Of The University Of Michigan | Methods and compositions for regulating FAS-associated apoptosis |
US5786173A (en) | 1996-03-19 | 1998-07-28 | Idun Pharmaceuticals, Inc. | MCH4 and MCH5, apoptotic protease, nucleic acids encoding and methods of use |
US5712115A (en) | 1996-03-19 | 1998-01-27 | Incyte Pharmaceuticals, Inc. | Human cell death-associated protein |
US6008042A (en) * | 1996-05-16 | 1999-12-28 | Smithkline Beecham Corporation | Interleukin-1 beta converting enzyme like apoptotic protease-7 |
AU6162496A (en) | 1996-06-05 | 1998-01-05 | Human Genome Sciences, Inc. | Interleukin-1 beta converting enzyme like apoptotic protease-7 |
US5837837A (en) | 1997-02-27 | 1998-11-17 | Millennium Pharmaceuticals, Inc. | Nucleic acids molecules encoding Caspase-8h and Caspase-8i |
DE19713393C2 (de) | 1997-04-01 | 2002-12-05 | Apotech Res & Dev Ltd | Flip-Gen und Flip-Protein |
-
1995
- 1995-07-16 IL IL11461595A patent/IL114615A0/xx unknown
-
1996
- 1996-06-14 MX MX9800537A patent/MX9800537A/es active IP Right Grant
- 1996-06-14 SI SI9630778T patent/SI2042509T1/sl unknown
- 1996-06-14 CA CA2226973A patent/CA2226973C/en not_active Expired - Lifetime
- 1996-06-14 SI SI9630769T patent/SI0914325T1/sl unknown
- 1996-06-14 EP EP08018971A patent/EP2042509B1/en not_active Expired - Lifetime
- 1996-06-14 DK DK08018971.5T patent/DK2042509T3/da active
- 1996-06-14 EP EP96919472A patent/EP0914325B1/en not_active Expired - Lifetime
- 1996-06-14 ES ES96919472T patent/ES2326704T3/es not_active Expired - Lifetime
- 1996-06-14 WO PCT/US1996/010521 patent/WO1997003998A1/en not_active Application Discontinuation
- 1996-06-14 KR KR10-1998-0700354A patent/KR100491095B1/ko active IP Right Grant
- 1996-06-14 PT PT96919472T patent/PT914325E/pt unknown
- 1996-06-14 ES ES08018971T patent/ES2405657T3/es not_active Expired - Lifetime
- 1996-06-14 PT PT80189715T patent/PT2042509E/pt unknown
- 1996-06-14 DE DE69637931T patent/DE69637931D1/de not_active Expired - Lifetime
- 1996-06-14 JP JP50667597A patent/JP3980641B2/ja not_active Expired - Lifetime
- 1996-06-14 DK DK96919472T patent/DK0914325T3/da active
- 1996-06-14 AT AT96919472T patent/ATE431357T1/de active
- 1996-06-14 CN CNB961966580A patent/CN100390195C/zh not_active Expired - Lifetime
- 1996-06-14 AU AU61805/96A patent/AU708799B2/en not_active Expired
-
1998
- 1998-01-15 NO NO19980198A patent/NO321092B1/no not_active IP Right Cessation
-
1999
- 1999-05-04 HK HK99101995A patent/HK1016990A1/xx not_active IP Right Cessation
-
2000
- 2000-03-01 US US09/516,747 patent/US6586571B1/en not_active Expired - Lifetime
-
2003
- 2003-02-20 US US10/368,438 patent/US20030219411A1/en not_active Abandoned
-
2006
- 2006-09-18 US US11/522,472 patent/US7799901B2/en not_active Expired - Fee Related
Also Published As
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