IL111125A0 - Soluble oligomeric tnf/ngf super family ligand receptors and their use - Google Patents

Soluble oligomeric tnf/ngf super family ligand receptors and their use

Info

Publication number
IL111125A0
IL111125A0 IL11112594A IL11112594A IL111125A0 IL 111125 A0 IL111125 A0 IL 111125A0 IL 11112594 A IL11112594 A IL 11112594A IL 11112594 A IL11112594 A IL 11112594A IL 111125 A0 IL111125 A0 IL 111125A0
Authority
IL
Israel
Prior art keywords
ngf
family ligand
super family
soluble oligomeric
ligand receptors
Prior art date
Application number
IL11112594A
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL109632A external-priority patent/IL109632A/en
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL11112594A priority Critical patent/IL111125A0/en
Publication of IL111125A0 publication Critical patent/IL111125A0/en
Priority to PCT/US1995/005854 priority patent/WO1995031544A1/en
Priority to JP52974895A priority patent/JP3966387B2/en
Priority to EP95919787A priority patent/EP0759984A4/en
Priority to CNB951940953A priority patent/CN1173033C/en
Priority to KR1019960706405A priority patent/KR100404737B1/en
Priority to CNB2004100748451A priority patent/CN1329512C/en
Priority to CA002490080A priority patent/CA2490080A1/en
Priority to CA002189983A priority patent/CA2189983A1/en
Priority to AU25469/95A priority patent/AU703919B2/en
Priority to MX9605531A priority patent/MX9605531A/en
Priority to NO19964741A priority patent/NO321514B1/en
Priority to FI964509A priority patent/FI964509A/en
Priority to AU97160/98A priority patent/AU714907B2/en
Priority to US10/349,977 priority patent/US7186682B2/en
Priority to US11/615,609 priority patent/US20070232520A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
IL11112594A 1994-05-11 1994-10-02 Soluble oligomeric tnf/ngf super family ligand receptors and their use IL111125A0 (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IL11112594A IL111125A0 (en) 1994-05-11 1994-10-02 Soluble oligomeric tnf/ngf super family ligand receptors and their use
AU25469/95A AU703919B2 (en) 1994-05-11 1995-05-11 Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors
MX9605531A MX9605531A (en) 1994-10-02 1995-05-11 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors.
KR1019960706405A KR100404737B1 (en) 1994-05-11 1995-05-11 Tumor Necrosis Factor / Nerve Growth Factor (TNF / NGF) Superfamily Receptor and Water-soluble Oligomeric Tumor Necrosis Factor / Nerve Growth Factor
CA002189983A CA2189983A1 (en) 1994-05-11 1995-05-11 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors
EP95919787A EP0759984A4 (en) 1994-05-11 1995-05-11 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors
CNB951940953A CN1173033C (en) 1994-05-11 1995-05-11 Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors
PCT/US1995/005854 WO1995031544A1 (en) 1994-05-11 1995-05-11 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors
CNB2004100748451A CN1329512C (en) 1994-05-11 1995-05-11 Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors
CA002490080A CA2490080A1 (en) 1994-05-11 1995-05-11 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors
JP52974895A JP3966387B2 (en) 1994-05-11 1995-05-11 TNF / NGF superfamily receptors and soluble oligomers Modulators of TNF / NGF superfamily receptors
FI964509A FI964509A (en) 1994-05-11 1996-11-08 TNF / NGF superfamily receptor transformers and soluble, oligomeric superfamily receptors
NO19964741A NO321514B1 (en) 1994-05-11 1996-11-08 DNA sequence encoding modulators of TNF / NGF superfamily receptors, as well as protein, pharmaceutical composition, vector, methods and uses thereof.
AU97160/98A AU714907B2 (en) 1994-05-11 1998-12-17 Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors
US10/349,977 US7186682B2 (en) 1994-05-11 2003-01-24 Modulator of TNF/NGF superfamily receptors and soluble oligomeric TNF/NGF superfamily receptors
US11/615,609 US20070232520A1 (en) 1994-05-11 2006-12-22 Modulator of tnf/ngf superfamily receptors and soluble oligomeric tnf/ngf superfamily receptors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL109632A IL109632A (en) 1994-05-11 1994-05-11 Modulators of the function of tnf receptors
IL11112594A IL111125A0 (en) 1994-05-11 1994-10-02 Soluble oligomeric tnf/ngf super family ligand receptors and their use

Publications (1)

Publication Number Publication Date
IL111125A0 true IL111125A0 (en) 1994-12-29

Family

ID=26322830

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11112594A IL111125A0 (en) 1994-05-11 1994-10-02 Soluble oligomeric tnf/ngf super family ligand receptors and their use

Country Status (10)

Country Link
EP (1) EP0759984A4 (en)
JP (1) JP3966387B2 (en)
KR (1) KR100404737B1 (en)
CN (2) CN1173033C (en)
AU (1) AU703919B2 (en)
CA (1) CA2189983A1 (en)
FI (1) FI964509A (en)
IL (1) IL111125A0 (en)
NO (1) NO321514B1 (en)
WO (1) WO1995031544A1 (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5663070A (en) * 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5852173A (en) * 1994-10-19 1998-12-22 Genetics Institute, Inc. TNF receptor death ligand proteins and inhibitors of ligand binding
US5849501A (en) * 1994-10-19 1998-12-15 Genetics Institute, Inc. TNF receptor death domain ligand proteins and method to identify inhibitors of ligand binding
US5712381A (en) * 1994-10-19 1998-01-27 Genetics Institute, Inc. MADD, a TNF receptor death domain ligand protein
US5847099A (en) * 1994-10-19 1998-12-08 Genetics Institute, Inc. TNF receptor death domain ligand proteins
IL114615A0 (en) 1995-07-16 1995-11-27 Yeda Res & Dev Modulators of the function of fas receptors and other proteins
US7097972B1 (en) 1995-02-13 2006-08-29 Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6060238A (en) * 1995-02-13 2000-05-09 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
US6015665A (en) * 1995-02-13 2000-01-18 The Regents Of The University Of Michigan Method and composition for regulating apoptosis
WO1996025941A1 (en) * 1995-02-22 1996-08-29 Yeda Research And Development Co. Ltd. Modulators of regulatory proteins
US6355780B1 (en) 1995-02-22 2002-03-12 Yeda Research And Development Co. Ltd. Antibodies to the death domain motifs of regulatory proteins
US6747138B1 (en) 1995-04-03 2004-06-08 Regents Of The University Of Michigan Methods and compositions for regulating Fas-associated apoptosis
US7807783B1 (en) 1995-04-03 2010-10-05 The Regents Of The University Of Michigan Methods and compositions for regulating FAS-associated apoptosis
US6399327B1 (en) 1995-07-16 2002-06-04 Yeda Research And Development Co. Ltd. Modulators of the function of FAS receptors and other proteins
US6998116B1 (en) 1996-01-09 2006-02-14 Genentech, Inc. Apo-2 ligand
US6030945A (en) * 1996-01-09 2000-02-29 Genentech, Inc. Apo-2 ligand
EP1541689B1 (en) 1996-02-20 2012-09-05 Merck Serono SA Hybrid proteins which form heterodimers
NZ331539A (en) 1996-02-20 2000-01-28 Applied Research Systems Hybrid proteins from two coexpressed receptors to form a heterodimer
EP1500702A1 (en) 1996-04-01 2005-01-26 Genentech, Inc. APO-2LI and APO-3 apoptosis polypeptides from the TNFR1 familiy
AU6721696A (en) * 1996-07-15 1998-03-06 Human Genome Sciences, Inc. Cd44-like protein
US6462176B1 (en) 1996-09-23 2002-10-08 Genentech, Inc. Apo-3 polypeptide
EP0960126A4 (en) 1996-11-05 2004-05-19 Univ Texas Compositions and uses for sentrin, a cell-death protecting protein
US6593456B1 (en) 1996-11-06 2003-07-15 The Regents Of The University Of California Tumor necrosis factor receptor releasing enzyme
NZ335864A (en) 1996-11-06 2001-09-28 Univ California Isolated tumor necrosis factor receptor releasing enzyme (TRRE), compositions comprising the enzyme and methods of the use in modulation of TNF levels
US6930084B1 (en) 1996-11-06 2005-08-16 The Regents Of The University Of California Treating arthritis with TNF receptor releasing enzyme
US5858990A (en) * 1997-03-04 1999-01-12 St. Elizabeth's Medical Center Fas ligand compositions for treatment of proliferative disorders
US6342369B1 (en) 1997-05-15 2002-01-29 Genentech, Inc. Apo-2-receptor
JP2002512521A (en) * 1997-05-30 2002-04-23 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド 32 human secreted proteins
US7001992B2 (en) 1997-05-30 2006-02-21 Human Genome Sciences, Inc. Antibodies to secreted protein HEMCM42
IL121746A0 (en) * 1997-06-05 1998-02-22 Yeda Res & Dev Modulators of intracellular cell death and cell survival pathways
US6051385A (en) * 1997-10-22 2000-04-18 The Regents Of The University Of Michigan Compositions and methods for identifying and testing therapeutics against HSV infection
WO1999028465A2 (en) * 1997-11-28 1999-06-10 The Regents Of The University Of California Pias molecules that recognize and bind stat proteins and uses thereof
DE69939732D1 (en) 1998-01-15 2008-11-27 Genentech Inc APO-2 LIGAND
US6207422B1 (en) 1998-04-17 2001-03-27 The Metrohealth System Protein that enhances expression of potassium channels on cell surfaces and nucleic acids that encode the same
EP1022027A1 (en) * 1999-01-22 2000-07-26 Applied Research Systems ARS Holding N.V. Tumor necrosis factor antagonists and their use in endometriosis
JP2001078776A (en) 1999-09-14 2001-03-27 Inst Of Physical & Chemical Res Nade-binding protein
US9791452B2 (en) 2008-12-10 2017-10-17 Joslin Diabetes Center, Inc. Methods of diagnosing and predicting renal disease
WO2014127835A1 (en) 2013-02-22 2014-08-28 Christian-Albrechts-Universität Zu Kiel Plant-derived resistance gene

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
ATE194384T1 (en) * 1989-09-12 2000-07-15 Hoffmann La Roche TNF-BINDING PROTEINS
EP0510691B1 (en) * 1991-04-26 2004-11-03 Osaka Bioscience Institute DNA coding for human cell surface antigen

Also Published As

Publication number Publication date
NO964741D0 (en) 1996-11-08
JPH10500568A (en) 1998-01-20
EP0759984A1 (en) 1997-03-05
CN1173033C (en) 2004-10-27
FI964509A (en) 1997-01-09
CA2189983A1 (en) 1995-11-23
WO1995031544A1 (en) 1995-11-23
NO321514B1 (en) 2006-05-15
JP3966387B2 (en) 2007-08-29
NO964741L (en) 1997-01-09
AU2546995A (en) 1995-12-05
FI964509A0 (en) 1996-11-08
CN1616661A (en) 2005-05-18
EP0759984A4 (en) 2002-06-26
CN1152937A (en) 1997-06-25
KR970703419A (en) 1997-07-03
CN1329512C (en) 2007-08-01
AU703919B2 (en) 1999-04-01
KR100404737B1 (en) 2004-05-03

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