MX9703676A - Immunogens for stimulating mucosal immunity. - Google Patents

Immunogens for stimulating mucosal immunity.

Info

Publication number
MX9703676A
MX9703676A MX9703676A MX9703676A MX9703676A MX 9703676 A MX9703676 A MX 9703676A MX 9703676 A MX9703676 A MX 9703676A MX 9703676 A MX9703676 A MX 9703676A MX 9703676 A MX9703676 A MX 9703676A
Authority
MX
Mexico
Prior art keywords
immunogens
mucosal immunity
stimulating mucosal
pathogen
mucosal
Prior art date
Application number
MX9703676A
Other languages
Spanish (es)
Inventor
Michael Richard Lebens
Jan Roland Holmgren
Original Assignee
Maxim Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maxim Pharm Inc filed Critical Maxim Pharm Inc
Publication of MX9703676A publication Critical patent/MX9703676A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This patent application relates to immunogens for stimulating mucosal immunity to a pathogen capable of infecting its host through contact with mammalian mucosal membranes. In particular, this invention discloses a number of polypeptides and genetic constructs that include a membrane binding polypeptide operably linked to a peptide from a pathogen. Methods are detailed throughout the claims and the specification for introducing these immunogens into a mammal to stimulate mucosal immune responses.
MX9703676A 1994-11-17 1995-11-17 Immunogens for stimulating mucosal immunity. MX9703676A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34224194A 1994-11-17 1994-11-17
PCT/GB1995/002708 WO1996016178A1 (en) 1994-11-17 1995-11-17 Immunogens for stimulating mucosal immunity

Publications (1)

Publication Number Publication Date
MX9703676A true MX9703676A (en) 1998-03-31

Family

ID=23340968

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9703676A MX9703676A (en) 1994-11-17 1995-11-17 Immunogens for stimulating mucosal immunity.

Country Status (7)

Country Link
EP (1) EP0792365A1 (en)
JP (1) JPH10509325A (en)
CN (1) CN1173204A (en)
AU (1) AU3876795A (en)
CA (1) CA2205130A1 (en)
MX (1) MX9703676A (en)
WO (1) WO1996016178A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9626864D0 (en) * 1996-12-24 1997-02-12 Smithkline Beecham Biolog Vaccine
FR2766193B1 (en) 1997-07-18 2001-09-14 Inst Curie CHEMICAL POLYPEPTIDE COMPRISING FRAGMENT B OF TOXIN SHIGA AND PEPTIDES OF THERAPEUTIC INTEREST
US20020081307A1 (en) 1998-05-15 2002-06-27 Allan M. Green Verotoxin b subunit for immunization
CN100365120C (en) * 1998-12-08 2008-01-30 科里克萨有限公司 Compounds and methods for treatment and diagnosis of chlamydial infection
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
WO2002080648A2 (en) * 2001-04-05 2002-10-17 Chiron Corporation Mucosal boosting following parenteral priming
AU2002320314A1 (en) 2001-07-05 2003-01-21 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
CA2609038A1 (en) 2005-05-18 2006-11-23 Trinity Biosystems, Inc. Methods and compositions for immunizing against chlamydia infection
EP2190862A1 (en) * 2007-08-20 2010-06-02 New York University Immunogen presenting hiv gp120 v3 loop in a conformation that induces broadly neutralizing antibodies
CN106543287B (en) * 2015-09-16 2021-04-06 上海亨臻实业有限公司 Conformational epitope vaccines and uses
CN113813398B (en) * 2021-04-23 2023-11-07 天津医科大学 Method for delivering recombinant protein to cells with ganglioside-rich surface

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE143414T1 (en) * 1985-01-14 1996-10-15 Chiron Corp MAIN PROTEIN OF THE OUTER MEMBRANE OF CHLAMYDIA
AU4754490A (en) * 1988-12-07 1990-06-26 University Of Leicester Heat-labile toxin b subunit fusion proteins
JPH02181236A (en) * 1989-01-05 1990-07-16 Nec Corp Debug device
DE69005572T2 (en) * 1989-09-08 1994-04-07 Takeda Chemical Industries Ltd Fusion proteins and their production.
IL96475A0 (en) * 1989-11-29 1991-08-16 Innovative Tech Center Chimeric proteins
GB9112553D0 (en) * 1991-06-11 1991-07-31 Wellcome Found Fusion proteins

Also Published As

Publication number Publication date
EP0792365A1 (en) 1997-09-03
JPH10509325A (en) 1998-09-14
AU3876795A (en) 1996-06-17
CA2205130A1 (en) 1996-05-30
CN1173204A (en) 1998-02-11
WO1996016178A1 (en) 1996-05-30

Similar Documents

Publication Publication Date Title
FR19C1020I1 (en) NEW B7-4 MOLECULES AND THEIR USES
AU4778101A (en) Novel polypeptides, and nucleic acids encoding the same
AU7599500A (en) Novel gl50 molecules and uses therefor
BG100771A (en) Hematopoeic protein and ways and methods for its preparation
MX9703676A (en) Immunogens for stimulating mucosal immunity.
EP1798239A3 (en) G-protein coupled receptors and uses therefor
EP1847549A3 (en) Papillomavirus polyprotein constructs
HK1062444A1 (en) Methods and compounds for the targeting of protein to exosomes
ES8407097A1 (en) Fused genes encoding hybrid proteins, cloning vectors containing them and the use thereof.
UA42760C2 (en) Method of the direction of cellular immune response against the hiv-positive cell of mammal, membrane binding chimerical receptor protein, dna encoded chimerical receptor, vector containing thereof
EP1054683A4 (en) Modified heat shock protein-antigenic peptide complex
AU3885793A (en) Hyaluronan receptor (rhamm = receptor for hyluronan mediated mobility) and hyaluronan binding peptides
NZ333203A (en) Tumour antigen proteins, genes thereof, and tumour antigen peptides
CA2303478A1 (en) Group a streptococcal vaccines
GR3025978T3 (en) Ryegrass pollen allergen
WO2000070351A3 (en) Protein-protein interactions and methods for identifying them
WO2000059942A3 (en) Human obesity protein binding protrein-2 homolog and uses thereof
WO2002000718A3 (en) A human calcium channel protein and uses thereof
WO2002016591A3 (en) Human transporter family members and uses thereof
AU2001280639A1 (en) 13237,18480,2245 or 16228 human protein kinase molecules and uses therefor
CA2163805A1 (en) Novel activating factor of leukocytes
EP1900816A3 (en) GL50 molecules and uses therefor
AU2001253258A1 (en) Human trp-like calcium channel protein-2 (tlcc-2)
WO2000047229A3 (en) Polynucleotide encoding multimers of antigenic peptides in order to enhance presentation of the antigenic peptide by mhc molecules
WO2002029041A3 (en) 32146 and 57259, novel human transporters and uses thereof