AU2001253258A1 - Human trp-like calcium channel protein-2 (tlcc-2) - Google Patents

Human trp-like calcium channel protein-2 (tlcc-2)

Info

Publication number
AU2001253258A1
AU2001253258A1 AU2001253258A AU5325801A AU2001253258A1 AU 2001253258 A1 AU2001253258 A1 AU 2001253258A1 AU 2001253258 A AU2001253258 A AU 2001253258A AU 5325801 A AU5325801 A AU 5325801A AU 2001253258 A1 AU2001253258 A1 AU 2001253258A1
Authority
AU
Australia
Prior art keywords
tlcc
nucleic acid
calcium channel
acid molecules
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001253258A
Inventor
Rory A. J. Curtis
Inmaculada Silos-Santiago
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Millennium Pharmaceuticals Inc
Original Assignee
Millennium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharmaceuticals Inc filed Critical Millennium Pharmaceuticals Inc
Publication of AU2001253258A1 publication Critical patent/AU2001253258A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated TLCC-2 nucleic acid molecules, which encode novel TRP-like calcium channel molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing TLCC-2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a TLCC-2 gene has been introduced or disrupted. The invention still further provides isolated TLCC-2 proteins, fusion proteins, antigenic peptides and anti-TLCC-2 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
AU2001253258A 2000-04-07 2001-04-06 Human trp-like calcium channel protein-2 (tlcc-2) Abandoned AU2001253258A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54479700A 2000-04-07 2000-04-07
US09/544,797 2000-04-07
PCT/US2001/011442 WO2001077331A1 (en) 2000-04-07 2001-04-06 Human trp-like calcium channel protein-2 (tlcc-2)

Publications (1)

Publication Number Publication Date
AU2001253258A1 true AU2001253258A1 (en) 2001-10-23

Family

ID=24173629

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001253258A Abandoned AU2001253258A1 (en) 2000-04-07 2001-04-06 Human trp-like calcium channel protein-2 (tlcc-2)

Country Status (7)

Country Link
US (2) US20020035056A1 (en)
EP (1) EP1294872B1 (en)
AT (1) ATE419350T1 (en)
AU (1) AU2001253258A1 (en)
DE (1) DE60137222D1 (en)
ES (1) ES2319386T3 (en)
WO (1) WO2001077331A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7041448B2 (en) * 2000-08-18 2006-05-09 The ML4 Foundation Gene encoding a new TRP channel is mutated in mucolipidosis IV
DE10120834A1 (en) * 2001-04-27 2002-11-07 Boehringer Ingelheim Pharma New pain relievers that are inhibitors of TRP channels
WO2003068966A2 (en) * 2002-02-12 2003-08-21 Bayer Healthcare Ag REGULATION OF HUMAN Ca2+-PERMEABLE NONSELECTIVE CATION CHANNEL
WO2003087158A2 (en) * 2002-04-16 2003-10-23 Bayer Healthcare Ag Regulation of human transient receptor potential channel

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
CA2344100A1 (en) * 1998-09-23 2000-03-30 Human Genome Sciences, Inc. 31 human secreted proteins
JP2003527089A (en) * 1999-08-17 2003-09-16 インサイト・ゲノミックス・インコーポレイテッド Membrane-related proteins

Also Published As

Publication number Publication date
WO2001077331A1 (en) 2001-10-18
WO2001077331A9 (en) 2002-12-19
EP1294872B1 (en) 2008-12-31
DE60137222D1 (en) 2009-02-12
ES2319386T3 (en) 2009-05-07
EP1294872A1 (en) 2003-03-26
US20020197680A1 (en) 2002-12-26
ATE419350T1 (en) 2009-01-15
US20020035056A1 (en) 2002-03-21

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