MX9700928A - Derivado de triazian y medicina que lo contiene. - Google Patents

Derivado de triazian y medicina que lo contiene.

Info

Publication number
MX9700928A
MX9700928A MX9700928A MX9700928A MX9700928A MX 9700928 A MX9700928 A MX 9700928A MX 9700928 A MX9700928 A MX 9700928A MX 9700928 A MX9700928 A MX 9700928A MX 9700928 A MX9700928 A MX 9700928A
Authority
MX
Mexico
Prior art keywords
triazine derivative
medicine
nitrogen
substituted
nr1r2 represents
Prior art date
Application number
MX9700928A
Other languages
English (en)
Inventor
Fusao Ueda
Takayuki Ozaki
Ken-Ichi Nakamura
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of MX9700928A publication Critical patent/MX9700928A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invencion se relaciona con una composicion medicinal constituida de un derivado de triazina de la siguiente formula general (I): o un solvato del mismo, o una sal del mismo, como un ingrediente activo. En la formula anterior, R1 y R2 pueden ser iguales o diferentes y cada uno representa hidrogeno, alquilo, aralquilo, o alquenilo no sustituido o sustituido, o de manera conjunta representan amino cíclico (NR1R2) en combinacion con el átomo de nitrogeno adyacente. El amino cíclico puede contener nitrògeno, oxígeno o azufre como un miembro del anillo además del nitrogeno adyacente y de manera adicional puede estar sustituido. Se excluye el caso en cual NR1R2 es NH2. El compuesto de la invencion es util como un medicamento terapéutico para tratar la hepatitis.
MX9700928A 1994-08-08 1995-08-08 Derivado de triazian y medicina que lo contiene. MX9700928A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18581094 1994-08-08
PCT/JP1995/001577 WO1996004914A1 (fr) 1994-08-08 1995-08-08 Derive de triazine et medicament

Publications (1)

Publication Number Publication Date
MX9700928A true MX9700928A (es) 1997-04-30

Family

ID=16177293

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9700928A MX9700928A (es) 1994-08-08 1995-08-08 Derivado de triazian y medicina que lo contiene.

Country Status (10)

Country Link
EP (1) EP0775487A4 (es)
KR (1) KR970704444A (es)
AU (1) AU703263B2 (es)
BR (1) BR9508539A (es)
CA (1) CA2197091A1 (es)
HU (1) HUT77735A (es)
MX (1) MX9700928A (es)
RU (1) RU2147233C1 (es)
TW (1) TW340115B (es)
WO (1) WO1996004914A1 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4890196A (en) * 1995-03-09 1996-10-02 Nippon Shinyaku Co. Ltd. Remedy for pancreatitis
US5962454A (en) * 1995-04-20 1999-10-05 Nippon Shinyaku Co., Ltd. Neovascularization inhibitor
DE19704922A1 (de) 1997-02-10 1998-08-13 Hoechst Schering Agrevo Gmbh 2,4-Diamino-1,3,5-triazine, ihre Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
DE19735800A1 (de) * 1997-08-18 1999-02-25 Boehringer Ingelheim Pharma Triazine mit adenosinantagonistischer Wirkung
US6335339B1 (en) 1998-01-13 2002-01-01 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
EP1053230A1 (en) * 1998-01-13 2000-11-22 Scriptgen Pharmaceuticals, Inc. Triazine antiviral compounds
US6218408B1 (en) 1999-06-30 2001-04-17 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
ATE361917T1 (de) * 1999-04-22 2007-06-15 Lundbeck & Co As H Selektive npy(y5)-antagonisten
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US7273880B2 (en) 1999-06-30 2007-09-25 H. Lunbeck A/S Selective NPY (Y5) antagonists
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
WO2004000318A2 (en) 2002-06-21 2003-12-31 Cellular Genomics, Inc. Certain amino-substituted monocycles as kinase modulators
EP1644358A2 (en) * 2003-07-16 2006-04-12 Neurogen Corporation Biaryl piperazinyl-pyridine analogues
US7223759B2 (en) 2003-09-15 2007-05-29 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
MY145822A (en) 2004-08-13 2012-04-30 Neurogen Corp Substituted biaryl piperazinyl-pyridine analogues
GB2465405A (en) * 2008-11-10 2010-05-19 Univ Basel Triazine, pyrimidine and pyridine analogues and their use in therapy
CN102344416B (zh) * 2010-08-02 2015-09-16 中国人民解放军军事医学科学院毒物药物研究所 哒嗪衍生物及其作为抗小rna病毒感染药物的用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5845429B2 (ja) * 1976-03-29 1983-10-08 日本新薬株式会社 ベンゾグアナミン誘導体
JPS5735587A (en) * 1980-06-04 1982-02-26 Nippon Shinyaku Co Ltd Benzoguanamine derivative
JPS57203083A (en) * 1981-06-05 1982-12-13 Nippon Shinyaku Co Ltd Nicotinic acid derivative
JPS5855423A (ja) * 1981-09-25 1983-04-01 Nippon Shinyaku Co Ltd ベンゾグアナミン類を主成分としする医薬
JPS59106473A (ja) * 1982-12-10 1984-06-20 Nippon Shinyaku Co Ltd トリアジン誘導体
AU6058690A (en) * 1989-08-09 1991-03-11 Nippon Shinyaku Co. Ltd. Remedy

Also Published As

Publication number Publication date
TW340115B (en) 1998-09-11
WO1996004914A1 (fr) 1996-02-22
KR970704444A (ko) 1997-09-06
AU703263B2 (en) 1999-03-25
BR9508539A (pt) 1997-10-28
RU2147233C1 (ru) 2000-04-10
CA2197091A1 (en) 1996-02-22
EP0775487A4 (en) 1999-03-10
AU3192095A (en) 1996-03-07
HUT77735A (hu) 1998-07-28
EP0775487A1 (en) 1997-05-28

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