MX9605313A - Proceso para preparar intermediarios para la sintesis de agentes antifungicos. - Google Patents

Proceso para preparar intermediarios para la sintesis de agentes antifungicos.

Info

Publication number
MX9605313A
MX9605313A MX9605313A MX9605313A MX9605313A MX 9605313 A MX9605313 A MX 9605313A MX 9605313 A MX9605313 A MX 9605313A MX 9605313 A MX9605313 A MX 9605313A MX 9605313 A MX9605313 A MX 9605313A
Authority
MX
Mexico
Prior art keywords
synthesis
antifungal agents
preparing intermediates
alkyl
formula
Prior art date
Application number
MX9605313A
Other languages
English (en)
Inventor
Anantha Sudhakar
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of MX9605313A publication Critical patent/MX9605313A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62—Halogen-containing esters
    • C07C69/65—Halogen-containing esters of unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se da a conocer un proceso para la preparacion de los compuestos de la formula I (Ver Formula); donde R representa alquilo C1-C6, que comprende el calentamiento de una mezcla de un derivado de difluorbenceno, aleno, un dialquilmalonato de la formula CH2(CO2R)2, donde R representa alquilo C1-C6 y una base, en un solvente orgánico polar en presencia de un catalizador, en un recipiente sellado y con una presion dentro del recipiente de 1 a 10 psig.
MX9605313A 1994-05-09 1995-05-04 Proceso para preparar intermediarios para la sintesis de agentes antifungicos. MX9605313A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/239,488 US5442093A (en) 1994-05-09 1994-05-09 Process for preparing intermediates for the synthesis of antifungal agents
PCT/US1995/005216 WO1995030638A1 (en) 1994-05-09 1995-05-04 Process for preparing intermediates for the synthesis of antifungal agents

Publications (1)

Publication Number Publication Date
MX9605313A true MX9605313A (es) 1997-12-31

Family

ID=22902372

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9605313A MX9605313A (es) 1994-05-09 1995-05-04 Proceso para preparar intermediarios para la sintesis de agentes antifungicos.

Country Status (15)

Country Link
US (1) US5442093A (es)
EP (1) EP0759024B1 (es)
JP (1) JP3744538B2 (es)
KR (1) KR970702838A (es)
CN (1) CN1088056C (es)
AT (1) ATE196133T1 (es)
AU (1) AU701315B2 (es)
CA (1) CA2189128C (es)
DE (1) DE69518748T2 (es)
ES (1) ES2150568T3 (es)
HU (1) HUT75109A (es)
IL (1) IL113628A (es)
MX (1) MX9605313A (es)
NZ (1) NZ285508A (es)
WO (1) WO1995030638A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ325566A (en) * 1995-12-20 1999-05-28 Schering Corp Process for preparing a crystalline chiral hydroxy ester intermediate for the synthesis of antifungal agents
US5756830A (en) * 1995-12-20 1998-05-26 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents
DE19827417B4 (de) * 1998-06-19 2004-10-28 Hahn, Rainer, Dr.Med.Dent. Material zur unterschiedlichen Modifizierung der optischen Eigenschaften unterschiedlicher Zellen
KR20060050746A (ko) 2004-08-31 2006-05-19 엘지전자 주식회사 카메라로 촬영된 문서 영상 처리 방법
CN105777539B (zh) * 2016-03-30 2018-04-10 浙江大学宁波理工学院 一种2‑[2‑（2，4‑二氟苯基）烯丙基]‑1，3‑丙二酸二乙酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE115577T1 (de) * 1987-11-20 1994-12-15 Schering Corp Tri- und tetrasubstituierte oxetane und tetrahydrofurane und deren zwischenprodukte.
US5039676A (en) * 1990-05-11 1991-08-13 Schering Corporation Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
US5349099A (en) * 1993-12-13 1994-09-20 Schering Corporation Process for preparing intermediates for the synthesis of antifungal agents

Also Published As

Publication number Publication date
ATE196133T1 (de) 2000-09-15
US5442093A (en) 1995-08-15
HUT75109A (en) 1997-04-28
DE69518748T2 (de) 2001-05-31
NZ285508A (en) 1998-02-26
IL113628A (en) 2000-07-26
CN1147807A (zh) 1997-04-16
KR970702838A (ko) 1997-06-10
CA2189128A1 (en) 1995-11-16
HU9603113D0 (en) 1997-01-28
EP0759024A1 (en) 1997-02-26
EP0759024B1 (en) 2000-09-06
JPH09512820A (ja) 1997-12-22
ES2150568T3 (es) 2000-12-01
CA2189128C (en) 2005-01-11
IL113628A0 (en) 1995-08-31
JP3744538B2 (ja) 2006-02-15
DE69518748D1 (de) 2000-10-12
AU701315B2 (en) 1999-01-28
WO1995030638A1 (en) 1995-11-16
AU2462495A (en) 1995-11-29
CN1088056C (zh) 2002-07-24

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