MX9603194A - Antagonistas de neuroquinina a ciclicos. - Google Patents
Antagonistas de neuroquinina a ciclicos.Info
- Publication number
- MX9603194A MX9603194A MX9603194A MX9603194A MX9603194A MX 9603194 A MX9603194 A MX 9603194A MX 9603194 A MX9603194 A MX 9603194A MX 9603194 A MX9603194 A MX 9603194A MX 9603194 A MX9603194 A MX 9603194A
- Authority
- MX
- Mexico
- Prior art keywords
- antagonists
- neurokinin
- cyclic
- cyclic neurokinin
- antagonism
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Se describen antagonistas de neuroquinina A que son compuestos de hexapéptido y octapéptido cíclicos novedosos. El antagonismo se confirma empleando ensayos bioquímicos y de enlace competitivo convencionales, así como pruebas fisiologicas convencionales, y también se describe el uso de estos derivados en una variedad de condiciones en donde se implica a la neuroquinina A.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/191,571 US5521156A (en) | 1994-02-03 | 1994-02-03 | Cyclic neurokinin A antagonists |
PCT/US1995/000296 WO1995021187A1 (en) | 1994-02-03 | 1995-01-10 | Cyclic neurokinin a antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9603194A true MX9603194A (es) | 1997-05-31 |
Family
ID=22706020
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9603194A MX9603194A (es) | 1994-02-03 | 1995-01-10 | Antagonistas de neuroquinina a ciclicos. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5521156A (es) |
EP (1) | EP0741743B1 (es) |
JP (2) | JPH09511490A (es) |
KR (3) | KR100378726B1 (es) |
CN (1) | CN1139931A (es) |
AT (1) | ATE172205T1 (es) |
AU (1) | AU691246B2 (es) |
CA (1) | CA2182486C (es) |
DE (1) | DE69505351T2 (es) |
DK (1) | DK0741743T3 (es) |
ES (1) | ES2123234T3 (es) |
FI (1) | FI963074A0 (es) |
HU (1) | HUT74383A (es) |
IL (1) | IL112489A0 (es) |
MX (1) | MX9603194A (es) |
NO (1) | NO963255L (es) |
NZ (1) | NZ279595A (es) |
WO (1) | WO1995021187A1 (es) |
ZA (1) | ZA95710B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5830863A (en) * | 1988-06-20 | 1998-11-03 | Merrell Pharmaceuticals Inc. | Neurokinin A antagonists |
US5744120A (en) * | 1993-03-30 | 1998-04-28 | The Dupont Merick Pharmaceutical Company | Ternary radiopharmaceutical complexes |
US5521156A (en) * | 1994-02-03 | 1996-05-28 | Merrell Pharmaceuticals Inc. | Cyclic neurokinin A antagonists |
US5879659A (en) * | 1996-03-13 | 1999-03-09 | Dupont Pharmaceuticals Company | Ternary radiopharmaceutical complexes |
MX9709494A (es) * | 1996-12-04 | 1998-07-31 | Pfizer | Compuestos peptidicos ciclicos, procedimiento para su produccion, composiciones que los contienen y uso de los mismos. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4102877A (en) * | 1976-07-28 | 1978-07-25 | Merck & Co., Inc. | Cyclization of peptides |
US4659691A (en) * | 1985-02-08 | 1987-04-21 | Merck & Co., Inc. | Novel cyclic Hexapeptide LHRH antagonists |
IT1233696B (it) * | 1989-05-29 | 1992-04-14 | Menarini Farma Ind | Peptidi di sintesi antagonisti della neurochinina a. loro sali e relativi procedimenti di fabbricazione |
IT1241761B (it) * | 1990-08-03 | 1994-02-01 | Menarini Farma Ind | Peptidi di sintesi antagonisti della neurochinina a, loro sali e relativi procedimenti di fabbricazione |
ES2103857T3 (es) * | 1991-08-13 | 1997-10-01 | Takeda Chemical Industries Ltd | Peptidos ciclicos y su uso. |
US5521156A (en) * | 1994-02-03 | 1996-05-28 | Merrell Pharmaceuticals Inc. | Cyclic neurokinin A antagonists |
-
1994
- 1994-02-03 US US08/191,571 patent/US5521156A/en not_active Expired - Fee Related
-
1995
- 1995-01-10 KR KR1019960704192A patent/KR100378726B1/ko not_active IP Right Cessation
- 1995-01-10 NZ NZ279595A patent/NZ279595A/en unknown
- 1995-01-10 KR KR10-2002-7014406A patent/KR100380872B1/ko not_active IP Right Cessation
- 1995-01-10 DE DE69505351T patent/DE69505351T2/de not_active Expired - Fee Related
- 1995-01-10 MX MX9603194A patent/MX9603194A/es not_active Application Discontinuation
- 1995-01-10 CN CN95191462A patent/CN1139931A/zh active Pending
- 1995-01-10 JP JP7520264A patent/JPH09511490A/ja not_active Ceased
- 1995-01-10 HU HU9602157A patent/HUT74383A/hu unknown
- 1995-01-10 KR KR10-2002-7014405A patent/KR100380873B1/ko not_active IP Right Cessation
- 1995-01-10 ES ES95908459T patent/ES2123234T3/es not_active Expired - Lifetime
- 1995-01-10 WO PCT/US1995/000296 patent/WO1995021187A1/en active IP Right Grant
- 1995-01-10 DK DK95908459T patent/DK0741743T3/da active
- 1995-01-10 EP EP95908459A patent/EP0741743B1/en not_active Expired - Lifetime
- 1995-01-10 CA CA002182486A patent/CA2182486C/en not_active Expired - Fee Related
- 1995-01-10 AU AU16771/95A patent/AU691246B2/en not_active Ceased
- 1995-01-10 AT AT95908459T patent/ATE172205T1/de not_active IP Right Cessation
- 1995-01-30 ZA ZA95710A patent/ZA95710B/xx unknown
- 1995-01-31 IL IL11248995A patent/IL112489A0/xx unknown
-
1996
- 1996-08-02 NO NO963255A patent/NO963255L/no unknown
- 1996-08-02 FI FI963074A patent/FI963074A0/fi not_active IP Right Cessation
-
2004
- 2004-09-24 JP JP2004278581A patent/JP2005089471A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
ES2123234T3 (es) | 1999-01-01 |
KR100380872B1 (ko) | 2003-04-18 |
JPH09511490A (ja) | 1997-11-18 |
KR100380873B1 (ko) | 2003-04-18 |
ZA95710B (en) | 1995-10-16 |
NZ279595A (en) | 1997-12-19 |
CN1139931A (zh) | 1997-01-08 |
EP0741743A1 (en) | 1996-11-13 |
FI963074A (fi) | 1996-08-02 |
DE69505351D1 (de) | 1998-11-19 |
HU9602157D0 (en) | 1996-09-30 |
AU691246B2 (en) | 1998-05-14 |
AU1677195A (en) | 1995-08-21 |
FI963074A0 (fi) | 1996-08-02 |
CA2182486C (en) | 2002-10-08 |
KR100378726B1 (ko) | 2003-10-04 |
NO963255D0 (no) | 1996-08-02 |
CA2182486A1 (en) | 1995-08-10 |
US5521156A (en) | 1996-05-28 |
ATE172205T1 (de) | 1998-10-15 |
WO1995021187A1 (en) | 1995-08-10 |
JP2005089471A (ja) | 2005-04-07 |
DE69505351T2 (de) | 1999-06-02 |
DK0741743T3 (da) | 1999-06-23 |
IL112489A0 (en) | 1995-03-30 |
HUT74383A (en) | 1996-12-30 |
NO963255L (no) | 1996-10-02 |
EP0741743B1 (en) | 1998-10-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TR200001603T2 (tr) | Yeni bileşikler | |
MX9605128A (es) | Nuevos derivados de aminoacidos, procedimientos para su preparacion y composiciones farmaceuticas que contienen estos compuestos. | |
MX9705414A (es) | Antagonistas de vasopresina triciclicos. | |
HU9503826D0 (en) | Heterocycles useful as neurokinin antagonists | |
EG18081A (en) | Combination of angiotensin-converting enzyme inhibitors with calcium antagonists as well as the use indurugs | |
MX9702307A (es) | Pirrolo (2,3-d)pirimidinas y su uso. | |
IT1230803B (it) | Corredo per il collegamento a sicurezza di stabilita' di due macchine elettrodomestiche sovrapposte. | |
NO893431L (no) | Fremgangsmaate for fremstilling av neuropeptid y antagonister. | |
FR2799148B3 (fr) | Agrafeuse avec indication de la quantite d'agrafes restantes | |
AU1667500A (en) | N-(2-phenyl-4-piperidinybutyl)-5,6,7,8-tetrahydro-1-naphthal necarboxamides and their use as neurokinin 1 (nk1) and/or neurokinin 2 (nk2) receptor antagonists | |
PL337221A1 (en) | Carboxamides as antagonists of 5-ht1f | |
MX9704050A (es) | P-amidinobencilamidas de dipeptido novedosas con radicales sulfonilo o aminosulfonilo en terminal n. | |
TR199900363T2 (xx) | NK1 ve NK2 antagonistleri olarak asilaminoalkenilen-amid t�revleri. | |
HU9602157D0 (en) | Cyclic neurokinin a antagonists | |
CA2022740A1 (en) | Cyclic neurokinin a antagonists | |
EP0347802A3 (en) | Neurokinin a antagonists | |
MX9603199A (es) | Antagonistas de receptores a endotelina. | |
DE69805988D1 (de) | Herstellung von 1,3-diaminopentan durch hydrierung von 3-aminopentanitril | |
NZ330464A (en) | Methods for the preparation of biphenyl isoxazole sulfonamides | |
TR200000602T2 (tr) | Yeni karbonik asit türevleri, üretimleri ve kullanımları. | |
MY100938A (en) | Arylkylimidazole derivatives. | |
IE862569L (en) | Decapeptide antagonists of neurokinin b | |
PH25534A (en) | Alpha adrenergic receptor antagonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |