MX9600484A - Anhidrato de clorhidrato de paroxetina y procedimiento para su preparacion. - Google Patents
Anhidrato de clorhidrato de paroxetina y procedimiento para su preparacion.Info
- Publication number
- MX9600484A MX9600484A MX9600484A MX9600484A MX9600484A MX 9600484 A MX9600484 A MX 9600484A MX 9600484 A MX9600484 A MX 9600484A MX 9600484 A MX9600484 A MX 9600484A MX 9600484 A MX9600484 A MX 9600484A
- Authority
- MX
- Mexico
- Prior art keywords
- paroxetine hydrochloride
- solvent
- substantially free
- anhydrate
- organic solvent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere a anhidrato de clorhidrato de paroxetina sustancialmente libre de propan-2-ol ligado, varias formas de la anterior, procedimientos para prepararlo, nuevos intermediarios utiles para preparar lo anterior y métodos para tratar y/o prevenir ciertas enfermedades administrando los compuestos de la invencion a un ser humano que requiere del mismo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9502297.6A GB9502297D0 (en) | 1995-02-06 | 1995-02-06 | Novel compound |
GBGB9503112.6A GB9503112D0 (en) | 1995-02-17 | 1995-02-17 | Novel compound |
GBGB9509807.5A GB9509807D0 (en) | 1995-05-15 | 1995-05-15 | Novel compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
MX9600484A true MX9600484A (es) | 1997-01-31 |
MX198371B MX198371B (es) | 2000-08-29 |
Family
ID=27267578
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9600484A MX9600484A (es) | 1995-02-06 | 1996-02-02 | Anhidrato de clorhidrato de paroxetina y procedimiento para su preparacion. |
Country Status (47)
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3882224B2 (ja) | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
EP0812827B1 (en) | 1996-06-13 | 2009-09-02 | Sumitomo Chemical Company, Limited | Piperidine derivative as intermediates for the preparation of paroxetine and process for their preparation |
WO1998002556A2 (en) * | 1996-07-15 | 1998-01-22 | Smithkline Beecham Plc | Screening for and use of an esterase for a stereospecific resolution |
US6638948B1 (en) | 1996-09-09 | 2003-10-28 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
US5672612A (en) * | 1996-09-09 | 1997-09-30 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
CA2193939C (en) * | 1996-12-24 | 2002-02-12 | K.S. Keshava Murthy | Useful form of anhydrous paroxetine hydrochloride |
DE29724281U1 (de) * | 1997-06-10 | 2000-08-10 | Synthon Bv | 4-Phenylpiperidin-Verbindungen |
DE59801792D1 (de) * | 1997-08-08 | 2001-11-22 | Aventis Pharma Gmbh | Kristallform von N-(4-Trifluormethylphenyl)-5-methylisoxazol-4-carbonsäureamid |
GB9726907D0 (en) * | 1997-12-19 | 1998-02-18 | Smithkline Beecham Plc | Novel compounds |
CA2323896A1 (en) * | 1998-03-16 | 1999-09-23 | Andrew Simon Craig | Crystalline form of paroxetine |
GB9806312D0 (en) * | 1998-03-24 | 1998-05-20 | Smithkline Beecham Plc | Novel formulations |
US6699882B2 (en) | 1998-03-24 | 2004-03-02 | Smithkline Beecham P.L.C. | Paroxetine compositions |
AU2003200534B2 (en) * | 1998-03-24 | 2004-12-02 | Smithkline Beecham Plc | Paroxetine compositions |
JP3796351B2 (ja) * | 1998-04-13 | 2006-07-12 | 住友化学株式会社 | パロキセチン塩酸塩無水和物の乾燥方法 |
GB9812941D0 (en) * | 1998-06-16 | 1998-08-12 | Smithkline Beecham Plc | Method of treatment |
CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
ES2138937B1 (es) | 1998-07-07 | 2000-10-01 | Medichem Sa | Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen. |
EP1100796B1 (en) * | 1998-08-07 | 2003-05-02 | SmithKline Beecham plc | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride |
GB9824298D0 (en) * | 1998-11-05 | 1998-12-30 | Smithkline Beecham Plc | Novel process |
GB9826175D0 (en) * | 1998-11-28 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9826176D0 (en) * | 1998-11-28 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9826180D0 (en) * | 1998-11-30 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9826171D0 (en) * | 1998-11-30 | 1999-01-20 | Smithkline Beecham Plc | Novel compounds |
EP1135383B1 (en) * | 1998-11-30 | 2003-12-03 | SmithKline Beecham plc | Mixed paroxetine propan-2-ol solvates |
GB9826242D0 (en) * | 1998-11-30 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9826178D0 (en) * | 1998-11-30 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
GB9828767D0 (en) * | 1998-12-29 | 1999-02-17 | Smithkline Beecham Plc | Novel process |
ATE311883T1 (de) * | 1999-03-12 | 2005-12-15 | Aesica Pharmaceuticals Ltd | Stabile pharmazeutische anwendungsform für paroxetin-anhydrat |
GB9914583D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel process |
GB9914585D0 (en) * | 1999-06-22 | 1999-08-25 | Smithkline Beecham Plc | Novel process |
GB9919001D0 (en) * | 1999-08-12 | 1999-10-13 | Smithkline Beecham Plc | Novel process |
GB9923446D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
GB9923439D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
GB9923445D0 (en) * | 1999-10-04 | 1999-12-08 | Smithkline Beecham Plc | Novel process |
HU226912B1 (en) * | 2000-04-07 | 2010-03-01 | Richter Gedeon Nyrt | New paroxetin salt and medicament containing it |
WO2002022609A1 (fr) * | 2000-09-14 | 2002-03-21 | Asahi Glass Company, Limited | Procede de production de sel de paroxetine sensiblement exempt de solvant organique |
JP2005524656A (ja) * | 2002-02-22 | 2005-08-18 | テバ ファーマシューティカル インダストリーズ リミティド | 新規中間物質を用いるパロキセチンの調製 |
KR20080055990A (ko) * | 2005-11-22 | 2008-06-19 | 테바 파마슈티컬 인더스트리즈 리미티드 | 시나칼셋 HCl의 결정형 및 이의 제조 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
GB8430581D0 (en) * | 1984-12-04 | 1985-01-09 | Ferrosan As | Treatment |
EP0223403B1 (en) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Piperidine derivative, its preparation, and its use as medicament |
GB8626936D0 (en) * | 1986-11-11 | 1986-12-10 | Ferrosan As | Treatment |
DK716088D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Reduktion af piperidin-dion-derivater samt intermediat |
DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
KR930702000A (ko) * | 1990-11-24 | 1993-09-08 | 데이빗 로버츠 | 노년기 치매, 식용항진, 편두통, 또는 식용불량의 치료를 위한 파로세틴의 사용 |
GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
-
1996
- 1996-02-01 AR ARP960101230A patent/AR001982A1/es not_active Application Discontinuation
- 1996-02-01 SK SK143-96A patent/SK283608B6/sk not_active IP Right Cessation
- 1996-02-02 AU AU43328/96A patent/AU701518C/en not_active Ceased
- 1996-02-02 IE IE960104A patent/IE80500B1/en not_active IP Right Cessation
- 1996-02-02 MY MYPI96000383A patent/MY132529A/en unknown
- 1996-02-02 RO RO96-00183A patent/RO112426B1/ro unknown
- 1996-02-02 EP EP03078024A patent/EP1378508A1/en not_active Withdrawn
- 1996-02-02 WO PCT/EP1996/000447 patent/WO1996024595A1/en active IP Right Grant
- 1996-02-02 DE DE1996631298 patent/DE69631298T2/de not_active Expired - Lifetime
- 1996-02-02 AU AU47864/96A patent/AU4786496A/en not_active Abandoned
- 1996-02-02 EP EP01115079A patent/EP1136490B1/en not_active Expired - Lifetime
- 1996-02-02 MC MC2329A patent/MC2411A1/xx unknown
- 1996-02-02 EP EP96903970A patent/EP0808314B1/en not_active Expired - Lifetime
- 1996-02-02 DE DE19603797A patent/DE19603797C2/de not_active Revoked
- 1996-02-02 DE DE69621777T patent/DE69621777T2/de not_active Expired - Lifetime
- 1996-02-02 BR BR9600534A patent/BR9600534A/pt not_active IP Right Cessation
- 1996-02-02 LV LVP-96-31A patent/LV11618B/en unknown
- 1996-02-02 MX MX9600484A patent/MX9600484A/es not_active IP Right Cessation
- 1996-02-02 FR FR9601297A patent/FR2730232B1/fr not_active Expired - Fee Related
- 1996-02-02 CZ CZ0032096A patent/CZ297171B6/cs not_active IP Right Cessation
- 1996-02-03 SG SG1996000861A patent/SG43787A1/en unknown
- 1996-02-03 KR KR1019960002620A patent/KR100289885B1/ko not_active IP Right Cessation
- 1996-02-04 DZ DZ960030A patent/DZ1989A1/fr active
- 1996-02-05 SI SI9600036A patent/SI9600036B/sl not_active IP Right Cessation
- 1996-02-05 IL IL11703596A patent/IL117035A/xx unknown
- 1996-02-05 CA CA002210022A patent/CA2210022C/en not_active Expired - Fee Related
- 1996-02-05 GR GR960100038A patent/GR1002466B/el not_active IP Right Cessation
- 1996-02-05 UA UA96020442A patent/UA49796C2/uk unknown
- 1996-02-05 IT IT96MI000203A patent/IT1289532B1/it active IP Right Grant
- 1996-02-05 TW TW085101374A patent/TW503238B/zh not_active IP Right Cessation
- 1996-02-05 SI SI9600378A patent/SI21923B/sl not_active IP Right Cessation
- 1996-02-05 CA CA002210023A patent/CA2210023C/en not_active Expired - Fee Related
- 1996-02-05 LU LU88711A patent/LU88711A1/fr unknown
- 1996-02-05 HU HU9600255A patent/HUP9600255A1/hu unknown
- 1996-02-05 NL NL1002248A patent/NL1002248C2/xx not_active IP Right Cessation
- 1996-02-05 BG BG100333A patent/BG62967B1/bg unknown
- 1996-02-05 JP JP8018679A patent/JP2915338B2/ja not_active Expired - Fee Related
- 1996-02-05 CN CNB2004100855519A patent/CN1289496C/zh not_active Expired - Fee Related
- 1996-02-05 MA MA24157A patent/MA23802A1/fr unknown
- 1996-02-05 ES ES09600262A patent/ES2114471B1/es not_active Expired - Fee Related
- 1996-02-05 NO NO960472A patent/NO301009B1/no not_active IP Right Cessation
- 1996-02-05 CA CA002211522A patent/CA2211522C/en not_active Expired - Fee Related
- 1996-02-05 NZ NZ280943A patent/NZ280943A/en not_active IP Right Cessation
- 1996-02-05 DK DK011996A patent/DK11996A/da not_active Application Discontinuation
- 1996-02-05 FI FI960519A patent/FI111544B/fi not_active IP Right Cessation
- 1996-02-05 CN CN96103526A patent/CN1090187C/zh not_active Expired - Fee Related
- 1996-02-05 SE SE9600406A patent/SE521084C2/sv not_active IP Right Cessation
- 1996-02-05 BE BE9600101A patent/BE1009112A3/fr not_active IP Right Cessation
- 1996-02-05 RU RU96102180A patent/RU2125052C1/ru not_active IP Right Cessation
- 1996-02-05 AT AT0021096A patent/AT407528B/de not_active IP Right Cessation
- 1996-02-05 CA CA002168829A patent/CA2168829C/en not_active Expired - Fee Related
- 1996-02-05 PL PL96312646A patent/PL189247B1/pl unknown
- 1996-02-06 TR TR96/00096A patent/TR199600096A2/xx unknown
- 1996-02-06 CH CH00304/96A patent/CH688353A5/de not_active IP Right Cessation
- 1996-02-06 CH CH02051/98A patent/CH689804A5/de not_active IP Right Cessation
- 1996-02-06 CH CH01510/97A patent/CH689229A5/de not_active IP Right Cessation
- 1996-02-06 PT PT101827A patent/PT101827B/pt not_active IP Right Cessation
- 1996-02-06 OA OA60773A patent/OA10261A/en unknown
-
1997
- 1997-02-28 NO NO19970939A patent/NO311519B1/no not_active IP Right Cessation
- 1997-05-08 HK HK59397A patent/HK59397A/xx not_active IP Right Cessation
-
1998
- 1998-12-02 JP JP10342812A patent/JPH11228571A/ja active Pending
-
2000
- 2000-08-31 CN CN001268872A patent/CN1216055C/zh not_active Expired - Fee Related
-
2001
- 2001-02-12 DK DKPA200100223 patent/DK200100223A/da not_active Application Discontinuation
- 2001-10-18 NO NO20015070A patent/NO20015070D0/no not_active Application Discontinuation
-
2002
- 2002-10-18 AR ARP020103931A patent/AR036856A2/es unknown
-
2003
- 2003-02-03 FI FI20030162A patent/FI20030162A/fi unknown
- 2003-03-12 FI FI20030370A patent/FI20030370A/fi not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |