MX9206339A - Nueva proteina inhibidora de trombina a partir de chinches de monte - Google Patents

Nueva proteina inhibidora de trombina a partir de chinches de monte

Info

Publication number
MX9206339A
MX9206339A MX9206339A MX9206339A MX9206339A MX 9206339 A MX9206339 A MX 9206339A MX 9206339 A MX9206339 A MX 9206339A MX 9206339 A MX9206339 A MX 9206339A MX 9206339 A MX9206339 A MX 9206339A
Authority
MX
Mexico
Prior art keywords
pct
trombine
new
cys
gly
Prior art date
Application number
MX9206339A
Other languages
English (en)
Inventor
Thomas Friedrich
Siegfried Bialojan
Burkhard Kroeger
Christiph Kuenast
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of MX9206339A publication Critical patent/MX9206339A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855Proteins from animals other than mammals or birds
    • Y10S530/856Snakes; venom
MX9206339A 1991-11-06 1992-11-04 Nueva proteina inhibidora de trombina a partir de chinches de monte MX9206339A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4136513A DE4136513A1 (de) 1991-11-06 1991-11-06 Neues thrombininhibitorisches protein aus raubwanzen

Publications (1)

Publication Number Publication Date
MX9206339A true MX9206339A (es) 1993-05-01

Family

ID=6444190

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9206339A MX9206339A (es) 1991-11-06 1992-11-04 Nueva proteina inhibidora de trombina a partir de chinches de monte

Country Status (10)

Country Link
US (1) US5523287A (es)
EP (1) EP0612349B1 (es)
JP (1) JPH07500964A (es)
AT (1) ATE149568T1 (es)
CA (1) CA2121352A1 (es)
DE (2) DE4136513A1 (es)
DK (1) DK0612349T3 (es)
ES (1) ES2097931T3 (es)
MX (1) MX9206339A (es)
WO (1) WO1993009232A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19848785A1 (de) * 1998-10-22 2000-04-27 Max Planck Gesellschaft Gen für einen Thrombininhibitor aus Raubwanzen und Protein mit thrombinhemmender Wirkung
CZ301524B6 (cs) * 1999-03-18 2010-03-31 Merck Patent Gmbh Polypeptid z H. medicinalis, zpusob jeho prípravy a použití, farmaceutický prostredek, polynukleotid, expresní vektor, hostitelská bunka, protilátka a její použití
MY128992A (en) 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
WO2007038749A2 (en) * 2005-09-28 2007-04-05 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
US20110034396A1 (en) * 2005-09-28 2011-02-10 Biovascular, Inc. Methods and compositions for inhibiting cell migration and treatment of inflammatory conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1092421A (en) * 1964-02-28 1967-11-22 Nat Res Dev Improvements relating to anticoagulant materials
DE3819078A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
US5019056A (en) * 1988-09-22 1991-05-28 Aegis Medical, Inc. Bowel care apparatus
DE3931839A1 (de) * 1989-09-23 1991-04-04 Basf Ag Neue proteine und ihre herstellung

Also Published As

Publication number Publication date
ES2097931T3 (es) 1997-04-16
CA2121352A1 (en) 1993-05-13
DE59208142D1 (de) 1997-04-10
DE4136513A1 (de) 1993-05-13
EP0612349A1 (de) 1994-08-31
DK0612349T3 (da) 1997-07-28
WO1993009232A1 (de) 1993-05-13
ATE149568T1 (de) 1997-03-15
US5523287A (en) 1996-06-04
JPH07500964A (ja) 1995-02-02
EP0612349B1 (de) 1997-03-05

Similar Documents

Publication Publication Date Title
DE69736441D1 (de) Pharmazeutische zusammensetzung zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
PT723538E (pt) Compostos triciclicos de carbamato uteis para a ainibicao da funcao da proteina g e para o tratamento de doencas proliferativas
DE69822665D1 (de) Verwendung von 9-desoxy-2',9-alpha-methano-3-oxa-4,5,6-trinor-3,7-(1',3'-interphenylen)-13,14-dihydroprostaglandin-f1 zur behandlung von peripheren vaskulären erkrankungen
FI962591A (fi) Kasvuhormonia vapauttavia ominaisuuksia sisältäviä yhdisteitä
DE69625691D1 (de) Verabreichung von peptidylheterocyclen zur behandlung von thrombin in zusammenhang stehenden krankheiten
MY132529A (en) Paroxetine hydrochloride anhydrate
DE69030582T2 (de) Herstellung eines rekombinanten menschlichen interleukin-1-hemmers
SE9103332D0 (sv) Method for the diagnosis of blood coagulation desorders
DE69228997T2 (de) Menschliche il-3-varianten
NO941681L (no) Humane IL-4 mutant proteiner
DE69228749D1 (de) Neuartige polypeptide und ihre verwendung
FI973221A0 (fi) 1-aryyli-2-asyyliammo-etaaniyhdisteitä ja niiden käyttö neurokiniiniantagonisteina, erityisesti neurokiniini 1 antagonisteina
DE69225410T2 (de) Herstellung von n-acetylneuraminsäure-derivaten
DK0568554T3 (da) Fremgangsmåde til påvisning af anti-RNA-antistoffer
MX9206339A (es) Nueva proteina inhibidora de trombina a partir de chinches de monte
DE59206961D1 (de) Neue peptide (didemnine), ihre herstellung und verwendung
ES2108122T3 (es) Composicion a base de amilina o de un analogo de amilina conteniendo opcionalmente insulina, para el tratamiento de la anorexia y de las patologias asociadas.
DE69302375T2 (de) Kosmetische zusammensetzung zur erhaltung der frisur enthaltend ein milchprotein und/oder ein milchproteinhydrolysate und ein hydrolysate
BG103905A (en) New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine
DE69619530D1 (de) Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität
DE59006159D1 (de) Verwendung von macrolactonen als antiallergica.
ES2094930T3 (es) Nueva proteina inhibidora de trombina aislada de garrapatas.
DE69712182D1 (de) Peptide und ihre verwendung in der therapie von krankheiten des zöliakie-formenkreises
ES2109373T3 (es) Nueva proteina inhibidora de trombina a partir de garrapatas.
DK0825859T3 (da) Anvendelse af forskolin eller ekstrakter indeholdende dette til fremstilling af et lægemiddel til behandling af alkoholafhængighed