DE69619530D1 - Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität - Google Patents

Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität

Info

Publication number
DE69619530D1
DE69619530D1 DE69619530T DE69619530T DE69619530D1 DE 69619530 D1 DE69619530 D1 DE 69619530D1 DE 69619530 T DE69619530 T DE 69619530T DE 69619530 T DE69619530 T DE 69619530T DE 69619530 D1 DE69619530 D1 DE 69619530D1
Authority
DE
Germany
Prior art keywords
growth
humor
inhibiting activity
pct
somatostatin analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69619530T
Other languages
English (en)
Other versions
DE69619530T2 (de
Inventor
Romano Deghenghi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ardana Bioscience Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69619530D1 publication Critical patent/DE69619530D1/de
Publication of DE69619530T2 publication Critical patent/DE69619530T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE69619530T 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität Expired - Fee Related DE69619530T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001670A IT1277391B1 (it) 1995-07-28 1995-07-28 Peptidi ciclici analoghi della somatostatina ad attivita' inibitrice dell'ormone della crescita
PCT/EP1996/003149 WO1997005167A1 (en) 1995-07-28 1996-07-17 Somatostatin-analogous cyclic peptides with inhibitory activity on growth hormone

Publications (2)

Publication Number Publication Date
DE69619530D1 true DE69619530D1 (de) 2002-04-04
DE69619530T2 DE69619530T2 (de) 2002-08-08

Family

ID=11372091

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69619530T Expired - Fee Related DE69619530T2 (de) 1995-07-28 1996-07-17 Zyklische somatostatinanaloge mit wachstumhormon inhibierender aktivität

Country Status (15)

Country Link
US (1) US5962409A (de)
EP (1) EP0842193B1 (de)
JP (1) JPH11510147A (de)
KR (1) KR100321448B1 (de)
AT (1) ATE213742T1 (de)
AU (1) AU6700996A (de)
BR (1) BR9609801A (de)
CA (1) CA2227980A1 (de)
DE (1) DE69619530T2 (de)
DK (1) DK0842193T3 (de)
ES (1) ES2171704T3 (de)
HK (1) HK1008225A1 (de)
IT (1) IT1277391B1 (de)
PT (1) PT842193E (de)
WO (1) WO1997005167A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579967B1 (en) 1999-12-14 2003-06-17 The Salk Institute For Biological Studies Receptor-selective somatostatin analogs
GB0018891D0 (en) 2000-08-01 2000-09-20 Novartis Ag Organic compounds
US7019109B2 (en) * 2001-03-16 2006-03-28 The Salk Institute For Bilogical Studies SSTR1-selective analogs
US20040121407A1 (en) * 2002-09-06 2004-06-24 Elixir Pharmaceuticals, Inc. Regulation of the growth hormone/IGF-1 axis
CN1317031C (zh) * 2005-09-14 2007-05-23 上海第二医科大学附属新华医院 增强实体肿瘤细胞化疗敏感性的高效混合制剂
CA2933875C (en) 2005-11-21 2018-06-26 Novartis Ag 40-o-(2-hydroxyethyl)-rapamycin for use as a sole drug substance in the treatment of carcinoid tumors arising from the foregut, midgut, or hindgut
WO2013032012A1 (ja) * 2011-09-04 2013-03-07 株式会社糖鎖工学研究所 糖鎖付加ポリペプチドおよび当該ポリペプチドを含む医薬組成物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4725577A (en) * 1985-04-25 1988-02-16 Administrators Of The Tulane Educational Fund Biologically active lysine containing octapeptides
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
GR862206B (en) * 1985-09-12 1986-12-31 Univ Tulane Therapeutic somatostatin analogs
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
HU207104B (en) * 1991-01-25 1993-03-01 Biosignal Kutato Fejlesztoe Kf Process for producing new somatostatin analogs inhibiting tumour growth and pharmaceutical compositions comprising such compounds
CA2102633A1 (en) * 1991-06-03 1992-12-04 Peter H. Cox Radiolabelled somatostatin derivatives, their preparation and use
CA2110716C (en) * 1991-06-06 2003-10-28 Gary D. Lewis Optical cerebral oximeter

Also Published As

Publication number Publication date
KR100321448B1 (ko) 2002-07-31
US5962409A (en) 1999-10-05
WO1997005167A1 (en) 1997-02-13
KR19990035961A (ko) 1999-05-25
EP0842193B1 (de) 2002-02-27
BR9609801A (pt) 1999-07-06
PT842193E (pt) 2002-06-28
DE69619530T2 (de) 2002-08-08
HK1008225A1 (en) 1999-05-07
CA2227980A1 (en) 1997-02-13
AU6700996A (en) 1997-02-26
ES2171704T3 (es) 2002-09-16
ITMI951670A1 (it) 1997-01-28
EP0842193A1 (de) 1998-05-20
ITMI951670A0 (it) 1995-07-28
DK0842193T3 (da) 2002-04-29
JPH11510147A (ja) 1999-09-07
IT1277391B1 (it) 1997-11-10
ATE213742T1 (de) 2002-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ARDANA BIOSCIENCE LTD., EDINBURGH, GB

8381 Inventor (new situation)

Inventor name: DEGHENGHI, ROMANO, S.-CERGUE, CH

8339 Ceased/non-payment of the annual fee