MX366230B - Composiciones multipolimericas para liberación transdermica de farmaco. - Google Patents

Composiciones multipolimericas para liberación transdermica de farmaco.

Info

Publication number
MX366230B
MX366230B MX2015008286A MX2015008286A MX366230B MX 366230 B MX366230 B MX 366230B MX 2015008286 A MX2015008286 A MX 2015008286A MX 2015008286 A MX2015008286 A MX 2015008286A MX 366230 B MX366230 B MX 366230B
Authority
MX
Mexico
Prior art keywords
polymer
drug delivery
polymer compositions
transdermal drug
compositions
Prior art date
Application number
MX2015008286A
Other languages
English (en)
Other versions
MX2015008286A (es
Inventor
Kulakofsky Joshua
Liu Puchun
Original Assignee
Noven Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noven Pharma filed Critical Noven Pharma
Publication of MX2015008286A publication Critical patent/MX2015008286A/es
Publication of MX366230B publication Critical patent/MX366230B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen composiciones multipolimericas para la liberación transdermica de fármacos, tal como fármacos amino funcionales, en una forma flexible finita. Las composiciones comprenden una matriz polimerica que incluye un fármaco o una sal farmacéuticamente aceptable del mismo y una matriz polimerica que comprende polímeros acrílicos, polímeros de poliisobutileno y copolimeros en bloque de estireno - isopreno - estereno. También se describen métodos de elaboración y métodos para usar las composiciones.
MX2015008286A 2012-12-28 2013-12-27 Composiciones multipolimericas para liberación transdermica de farmaco. MX366230B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261747117P 2012-12-28 2012-12-28
PCT/US2013/077934 WO2014106016A1 (en) 2012-12-28 2013-12-27 Multi-polymer compositions for transdermal drug delivery

Publications (2)

Publication Number Publication Date
MX2015008286A MX2015008286A (es) 2015-12-09
MX366230B true MX366230B (es) 2019-07-03

Family

ID=49956518

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015008286A MX366230B (es) 2012-12-28 2013-12-27 Composiciones multipolimericas para liberación transdermica de farmaco.

Country Status (8)

Country Link
US (2) US9295726B2 (es)
EP (1) EP2938335B1 (es)
JP (1) JP6359032B2 (es)
AU (1) AU2013370297A1 (es)
CA (1) CA2896347A1 (es)
ES (1) ES2864327T3 (es)
MX (1) MX366230B (es)
WO (1) WO2014106016A1 (es)

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US8614716B2 (en) 2010-10-01 2013-12-24 Apple Inc. Recording a command stream with a rich encoding format for capture and playback of graphics content
TW201431554A (zh) 2012-12-28 2014-08-16 Noven Pharma 左炔諾孕酮（ｌｅｖｏｎｏｒｇｅｓｔｒｅｌ）及乙烯***之經皮藥物遞送系統
US11337936B2 (en) 2013-03-14 2022-05-24 Noven Pharmaceuticals, Inc. Amphetamine transdermal compositions with acrylic block copolymer
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
CN105607772B (zh) * 2014-11-13 2020-11-03 现代自动车株式会社 触摸输入装置以及包括该装置的车辆
TWI689321B (zh) 2015-02-06 2020-04-01 美商諾芬藥品公司 用於經皮藥物傳送之壓力敏感性黏合劑
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
JP7149287B2 (ja) 2016-12-20 2022-10-06 エルテーエス ローマン テラピー－ジステーメ アーゲー アセナピンおよびポリシロキサンまたはポリイソブチレンを含有する経皮治療システム
US20180193283A1 (en) 2016-12-20 2018-07-12 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
EP3644973B1 (en) 2017-06-26 2021-03-24 LTS LOHMANN Therapie-Systeme AG Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
BR112020026099A2 (pt) 2018-06-20 2021-03-23 Lts Lohmann Therapie-Systeme Ag sistema terapêutico transdérmico que contém asenapina
CA3203042A1 (en) 2021-01-07 2022-07-14 Deboprosad MONDAL Amphetamine carbamate compounds and methods
AR124577A1 (es) 2021-01-07 2023-04-12 Noven Pharma Composiciones transdérmicas de anfetamina con bajos niveles de carbamato

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US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5474783A (en) 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5719197A (en) 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5234957A (en) 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
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US6024974A (en) 1995-01-06 2000-02-15 Noven Pharmaceuticals, Inc. Composition and methods for transdermal delivery of acid labile drugs
AU718096C (en) 1995-06-07 2001-11-22 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
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EP2506838A1 (en) 2009-12-01 2012-10-10 Noven Pharmaceuticals, INC. Transdermal testosterone device and delivery
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CN103501770B (zh) * 2011-04-18 2015-04-29 久光制药株式会社 贴附剂的制造方法及贴附剂
CA2891467A1 (en) 2012-10-15 2014-04-24 Noven Pharmaceuticals, Inc. Compositions and methods for the transdermal delivery of methylphenidate
US9474722B2 (en) 2012-10-25 2016-10-25 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of amphetamine
TW201431554A (zh) 2012-12-28 2014-08-16 Noven Pharma 左炔諾孕酮（ｌｅｖｏｎｏｒｇｅｓｔｒｅｌ）及乙烯***之經皮藥物遞送系統
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Also Published As

Publication number Publication date
JP2016504368A (ja) 2016-02-12
WO2014106016A1 (en) 2014-07-03
CA2896347A1 (en) 2014-07-03
ES2864327T3 (es) 2021-10-13
US9295726B2 (en) 2016-03-29
EP2938335B1 (en) 2021-03-17
AU2013370297A1 (en) 2015-07-16
US20140186424A1 (en) 2014-07-03
JP6359032B2 (ja) 2018-07-18
US20170007548A1 (en) 2017-01-12
MX2015008286A (es) 2015-12-09
EP2938335A1 (en) 2015-11-04

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