MX363050B - Composición inmunogénica para modulación del sistema inmune y su uso, metodo de tratamiento y prevención de enfermedades, método para inducir la regeneración celular y procedimiento para la reconducción de la respuesta inmune. - Google Patents

Composición inmunogénica para modulación del sistema inmune y su uso, metodo de tratamiento y prevención de enfermedades, método para inducir la regeneración celular y procedimiento para la reconducción de la respuesta inmune.

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Publication number
MX363050B
MX363050B MX2013010669A MX2013010669A MX363050B MX 363050 B MX363050 B MX 363050B MX 2013010669 A MX2013010669 A MX 2013010669A MX 2013010669 A MX2013010669 A MX 2013010669A MX 363050 B MX363050 B MX 363050B
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Prior art keywords
diseases
present
treating
immune response
immune
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MX2013010669A
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MX2013010669A (es
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Alexandre Eduardo Nowill
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Alexandre Eduardo Nowill
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Publication of MX2013010669A publication Critical patent/MX2013010669A/es
Publication of MX363050B publication Critical patent/MX363050B/es

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Abstract

La presente invención se refiere a composiciones inmunogénicas para la modulación del sistema inmune que comprende una cantidad terapéuticamente efectiva de dos o más agentes antigénicos imunoactivos que presentan patrones moleculares asociados a patógenos (PAMPS) y / o patrones moleculares asociados a peligro (DAMPS) y o más de un vehículo, excipiente o diluyente fisiológicamente aceptable. Las composiciones inmunogénicas de la presente invención se utilizan en la fabricación de medicamentos para la prevención y / o tratamiento y en la prevención y / o tratamiento de enfermedades infecciosas, enfermedades autoinmunes, enfermedades alérgicas, inflamación, artritis, enfermedades inflamatorias, rechazo de trasplantes, enfermedades causadas por los trastornos vasculares, enfermedades causadas por eventos cardiovasculares hemorrágicos o isquémica, isquemia, infarto y hemorragia que conduce a destrucción del tejido cardiaca, renal, respiratoria o enfermedad de hígado, cáncer, tumores y lesiones benignas y malignas. La presente invención se refiere además a métodos para inducir la regeneración celular, la regeneración de tejidos, la regeneración de órganos y la regeneración de los sistemas orgánicos, tales como el sistema circulatorio, sistema nervioso y sistema endocrino. Por último, la presente invención se refiere a métodos para la renovación de la respuesta inmune en u animal, particularmente seres humanos.
MX2013010669A 2011-03-18 2012-03-19 Composición inmunogénica para modulación del sistema inmune y su uso, metodo de tratamiento y prevención de enfermedades, método para inducir la regeneración celular y procedimiento para la reconducción de la respuesta inmune. MX363050B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BRPI1100857-1A BRPI1100857A2 (pt) 2011-03-18 2011-03-18 agente imunomodulador e suas combinaÇÕes, seu uso e mÉtodo imunoterÁpico para a recontextualizaÇço, reprogramaÇço e reconduÇço do sistema imune em tempo real
PCT/BR2012/000072 WO2012122618A1 (pt) 2011-03-17 2012-03-19 Composição imunogênica para modulação do sistema imune e seu uso, método de tratamento e prevenção de doenças, método para induzir a regeneração celular e método para recondução da resposta imune

Publications (2)

Publication Number Publication Date
MX2013010669A MX2013010669A (es) 2014-10-14
MX363050B true MX363050B (es) 2019-03-06

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MX2013010669A MX363050B (es) 2011-03-18 2012-03-19 Composición inmunogénica para modulación del sistema inmune y su uso, metodo de tratamiento y prevención de enfermedades, método para inducir la regeneración celular y procedimiento para la reconducción de la respuesta inmune.

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US (1) US9566330B2 (es)
EP (1) EP2687227B1 (es)
JP (2) JP6181636B2 (es)
KR (1) KR102008535B1 (es)
CN (1) CN103717233B (es)
AU (1) AU2012229902B2 (es)
BR (2) BRPI1100857A2 (es)
CA (1) CA2837348A1 (es)
CL (1) CL2013002712A1 (es)
CO (1) CO6831973A2 (es)
DK (1) DK2687227T3 (es)
ES (1) ES2699264T3 (es)
MX (1) MX363050B (es)
PT (1) PT2687227T (es)
RU (1) RU2678317C2 (es)
WO (1) WO2012122618A1 (es)

Families Citing this family (39)

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Publication number Priority date Publication date Assignee Title
US10213504B2 (en) 2011-03-18 2019-02-26 Alexandre Eduardo Nowill Immunogenic composition for modulating the immune system and methods to treat bacterial infections in a subject
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
SG11201510150VA (en) 2013-06-21 2016-01-28 Ondek Pty Ltd Immunotherapy composition and use thereof
PE20170298A1 (es) 2014-03-28 2017-04-18 Opko Diagnostics Llc Composiciones y metodos relacionados con el diagnostico del cancer de prostata
KR101631312B1 (ko) * 2014-06-16 2016-06-20 연세대학교 산학협력단 재조합 람블편모충 결합 면역글로블린 단백질을 포함하는 면역증강 조성물
CN104546937B (zh) * 2014-09-30 2019-02-01 深圳华大基因科技有限公司 系结梭菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
HUE037476T2 (hu) 2014-12-23 2018-08-28 4D Pharma Res Ltd Pirin polipeptid és immunmodulálás
LT3065748T (lt) 2014-12-23 2018-03-12 4D Pharma Research Limited Bacteroides thetaiotaomicron padermė ir jos panaudojimas uždegimo sumažinimui
PT3253800T (pt) 2015-03-27 2021-04-28 Opko Diagnostics Llc Padrões de antigénio da próstata e suas utilizações
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
RS59308B1 (sr) 2015-06-15 2019-10-31 4D Pharma Res Ltd Kompozicije koje sadrže bakterijske sojeve
EP3636272A1 (en) 2015-06-15 2020-04-15 4D Pharma Research Limited Compositions comprising bacterial strains
LT3650033T (lt) 2015-06-15 2022-04-11 4D Pharma Research Limited Kompozicijos, apimančios bakterinius kamienus
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB2561748B (en) 2015-11-20 2019-05-08 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
TW201733601A (zh) 2016-03-04 2017-10-01 4D製藥有限公司 包含細菌菌株之組合物
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
TWI802545B (zh) 2016-07-13 2023-05-21 英商4D製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
IL268626B2 (en) * 2017-02-13 2024-04-01 Alexandre Eduardo Nowill Immunogenic preparations to adjust the immune system and methods to treat bacterial infections in the patient
MA48940A (fr) 2017-05-22 2020-04-08 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3630942B1 (en) 2017-05-24 2022-11-30 4D Pharma Research Limited Compositions comprising bacterial strain
MD3638271T2 (ro) 2017-06-14 2021-03-31 4D Pharma Res Ltd Compoziții cuprizând tulpini bacteriene
DK3804737T3 (da) 2017-06-14 2022-07-25 4D Pharma Res Ltd Sammensætninger omfattende bakteriestammer
RU2699540C2 (ru) * 2017-08-17 2019-09-06 Павел Павлович Несмиянов Композиция, содержащая пробиотические бактерии или их компоненты, и способ ее применения в лечении иммунных заболеваний кожи
AU2019215191A1 (en) * 2018-02-02 2020-09-17 University Of Washington Compositions and methods for inducing tripartite motif-containing protein 16 (trim16) signaling
CN109010824A (zh) * 2018-08-27 2018-12-18 广州汇高生物科技有限公司 一种特异性卵黄免疫球蛋白组合物及其制剂
WO2020106158A1 (en) * 2018-11-20 2020-05-28 Acd Pharmaceuticals As Serratia liquefaciens variant
ES2962407T3 (es) * 2018-12-04 2024-03-18 Sabiotec Spin Off S L Inmunoestimulante para su uso contra patógenos
CN110156885B (zh) * 2019-05-23 2020-11-24 南京林业大学 松材线虫的病原相关模式分子蛋白BxCDP1及其应用
WO2022040768A1 (en) * 2020-08-28 2022-03-03 Nowill Alexandre Eduardo Compositions for uses in methods of treating coronavirus infections
CN113244273A (zh) * 2021-03-16 2021-08-13 广州中科蓝华生物科技有限公司 疟原虫在制备联合放射疗法用于抗肿瘤的制剂中的应用
CN114606317B (zh) * 2022-03-22 2022-12-02 中山大学附属第一医院 一种预测胃癌***转移的菌群标志物及其应用
DE202023103094U1 (de) 2023-06-06 2023-06-30 Dasari Chandransh Ein System zur Regeneration menschlicher Zellen mit isoliertem regenerativem Gen eines Planarienorganismus

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
SI1659178T1 (sl) * 1998-02-05 2010-07-30 Glaxosmithkline Biolog Sa Postopek za čiščenje ali proizvodnjo MAGE proteina
US6432710B1 (en) * 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
AT410635B (de) * 2000-10-18 2003-06-25 Cistem Biotechnologies Gmbh Vakzin-zusammensetzung
WO2004096270A1 (en) * 2003-04-30 2004-11-11 Medi Service S.R.L. Immunomodulating composition comprising a particulate fraction of bacterial mechanical lysates
WO2005077408A2 (en) * 2004-02-06 2005-08-25 Vaxinnate Corporation Compositions of pamps and listeria monocytogenes and methods of use
PL1765391T3 (pl) * 2004-06-07 2013-08-30 Qu Biologics Inc Kompozycje bakteryjne do leczenia nowotworów
EP1807446A2 (en) * 2004-10-08 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Immunogenic and therapeutic compositions for streptococcus pyogenes
US20100047266A1 (en) * 2006-07-27 2010-02-25 Ligocyte Pharmaceuticals, Inc. Chimeric virus-like particles
EP2977456B1 (en) * 2006-08-15 2017-10-25 The Trustees Of The University Of Pennsylvania Compositions comprising hmw-maa and fragments thereof for treating cancer
EP1938835A1 (en) * 2006-12-29 2008-07-02 Pevion Biotech AG Non-specific immunostimulating agents
WO2009073133A1 (en) * 2007-11-29 2009-06-11 Vaxinnate Corporation Compositions of toll-like receptor agonists and papillomavirus antigens and uses thereof
EP2303236A4 (en) * 2008-07-01 2012-09-26 Univ Emory SYNERGISTIC INDUCTION OF HUMOR AND CELLULAR IMMUNITY BY COMBINATORY ACTIVATION OF TOLL-LIKE RECEPTORS
WO2010037402A1 (en) * 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
US20120093855A1 (en) * 2008-11-18 2012-04-19 Ligocyte Pharmaceuticals, Inc. RSV F VLPs AND METHODS OF MANUFACTURE AND USE THEREOF

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